[Prognostic factors for gastric cancer without lymph node involvement].

Abstract:

BACKGROUND:The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis. AIM:To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma. MATERIAL AND METHODS:Review of pathological records of a regional general hospital, identifying patients with a N0 gastric cancer surgically excised between 1986 and 2003. RESULTS:In the study period, 459 gastrectomies were performed for gastric cancer and in 32%, the tumor was devoid of lymph node involvement. These later patients were followed for a median of 64 months with a 71% five years actuarial survival. Bivariate analysis identified age, tumor size, gastric wall infiltration, pathological type according to Lauren and Ming, lymphovascular involvement, number of lymph nodes excised and TNM stage as prognostic values Multivariate analysis disclosed the level of gastric wall infiltration, the presence of a poorly differentiated tumor, lymphatic vascular involvement, number of excise lymph nodes and tumor size as independent prognostic factors. CONCLUSIONS:N0 gastric tumors are found in 32% of gastrectomies for gastric cancer and have a 71% five years actuarial survival. Gastric wall infiltration, pathological degree of differentiation tumor size and lymphovascular involvement are independent prognostic factors.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Tapia O,Villaseca M,Bellolio E,Araya JC,Roa JC

doi

/S0034-98872011000400003

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

432-8

issue

4

eissn

0034-9887

issn

0717-6163

pii

S0034-98872011000400003

journal_volume

139

pub_type

杂志文章
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