Abstract:
BACKGROUND:Patients on chronic hemodialysis have a lower immune response to vaccination against hepatitis B virus (HBV) than the general population. AIM:To identify factors that may interfere with immunization against hepatitis B virus (HBV) in Brazilian hemodialysis patients and analyze the evolution of the level of antibodies. PATIENTS AND METHODS:A retrospective longitudinal study, using records of patients on hemodialysis in the years 2000-2008. Non-responder patients, defined as a level of anti-HBs less than 10 IU/mL, were identified. The effect of social and demographic factors, clinical and laboratory data on the lack of response was evaluated. Logistic regression analysis was used to assess the independent effect of each factor. The difference between initial and final anti-HBs levels (24 months), was also analyzed. RESULTS:Fifty seven percent of patients responded adequately to vaccination. After adjustment with other variables, the only factor associated with immune response was serum ferritin. Responding patients of less than 40 years of age did not have a significant decrease in antibody titers over time. The initial anti-HBs title, influenced the final title. Fifty percent of non-responders achieved serum levels of protection after revaccination. CONCLUSIONS:The study showed that ferritin may be a marker of reduced immune response. Patients aged less than 40 years were the only ones who maintained over time their initial anti-HBs levels.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Pereira ZT,Mendoza-Sassi RAdoi
10.4067/S0034-98872012000700008subject
Has Abstractpub_date
2012-07-01 00:00:00pages
882-8issue
7eissn
0034-9887issn
0717-6163pii
S0034-98872012000700008journal_volume
140pub_type
杂志文章abstract::We are reporting a 37 year old male with severe oligozoospermia and a history of infertility for thirteen years and surgery for severe unilateral varicocele. The hormonal levels for FSH, LH and T, and karyotype were within the normal range. Multiplex PCR revealed the presence of a de novo microdeletion in the azoosper...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:A change in the social structure of medicine and its impact on clients has occurred in the last decades. AIM:To perform a survey about subjective wellbeing among physicians. MATERIAL AND METHODS:A physician’ professional satisfaction survey consisting in 90 questions, was applied to 580 physicians (7...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011001000009
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Mitral balloon valvuloplasty (MBV) is the therapy of choice for the treatment of symptomatic mitral stenosis with suitable anatomy. Although its short and mid-term results are favorable, there is a paucity of information about long-term follow-up. AIM:To assess the late results of MBV. MATERIAL AND METHODS...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014001100001
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:The economic impact of irritable bowel syndrome (IBS) in Mexico in terms of excessive diagnostic testing can be considerably reduced if the recommendations of the Latin American Consensus (LATAM) for IBS are followed. AIM:To estimate the economic impact of IBS in terms of excessive diagnostic testing. MATE...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872008001100005
更新日期:2008-11-01 00:00:00
abstract::Hemophagocytic syndrome is a severe condition of excessive immune activation that has a high mortality in the absence of treatment. The syndrome is classified as primary if associated with congenital or hereditary problems, or secondary/acquired if associated with infectious, autoimmune or oncology diseases. We report...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872015000900010
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Chronic obstructive pulmonary disease (COPD) has a relevant impact on health-related quality of life (HRQoL). Short Form 6 dimensions (SF-6D) quality of life tool allows researchers to calculate preference-based utilities using data from SF-12 or SF-36 questionnaires. AIM:To provide normative values of SF-6...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000200001
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Recent studies have described a high percentage of small intestinal bacterial overgrowth (SIBO) in patients with irritable bowel syndrome (IBS). However, the prevalence of SIBO has not been well established in other functional disorders. AIM:To evaluate the prevalence of SIBO in patients with different func...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872007001000003
更新日期:2007-10-01 00:00:00
abstract::Addisonian crisis as a first manifestation of metastatic disease secondary to cancer is uncommon. We report a 63-year-old man with a history of one year of fatigue, weakness, weight loss and repeated symptomatic hypoglycemia. The cortisol stimulation test with ACTH confirmed primary adrenal insufficiency. While receiv...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000900013
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:There are doubts wether generic medications have the same bioavailability and efficacy compared with the original drugs developed by pharmaceutical companies with research capabilities. AIM:To compare the pharmacokinetics and clinical (motor) responses of Sinemet and Grifoparkin (generic carbidopa/levodopa ...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-06-01 00:00:00
abstract::We report a 11 years old male diagnosed as a X-linked hyper-IgM syndrome that presented with recurrent infections and sclerosing cholangitis and later developed a gallbladder cancer. Immunological evaluation showed decreased levels of serum IgG and IgA with elevated levels of IgM. Study of CD40 ligand expression on mi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872007000400003
更新日期:2007-04-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::Mirizzi syndrome is estimated to occur in about 1% of cases requiring urgent or elective biliary tract surgery. The key anatomic finding is extrinsic compression of the common duct by a stone located in the gallbladder or cystic duct. Among patients operated on in the last 12 years we have found 77 patients meeting cr...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00
abstract::We report a 34-years-old male, with a history of hepatitis B and human immunodeficiency virus (HIV) infection that was admitted to the hospital with malaise, weight loss, frontal behavior and chest pain. Imaging studies showed two frontal cortical/subcortical nodules. A stereotactic cerebral biopsy showed reactive gli...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000200012
更新日期:2011-02-01 00:00:00
abstract::The new Chilean regulation about patients' rights and duties is generating a significant change in the information that health care professionals must provide to their patients. This issue will gravitate on medical liability. If this duty is accomplished incorrectly, professionals would fall into an illicit act and be...
journal_title:Revista medica de Chile
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
abstract::We evaluated pharmacokinetic parameters and bioavailability of 4 sustained release theophylline preparations. A crossover design was used in 12 healthy males aged 22 to 27 years old. Each individual received 250 mg iv followed by 250 mg orally of each preparation, and then 400 mg rapid acting aminophylline. A 7 day pe...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract::Hospitalization and death due to heart failure and cardiogenic shock is frequent and currently is increasing among the adult population. Although cardiac transplantation is the most effective treatment in patients with end-stage heart failure, its availability is limited. While waiting for transplantation, some patien...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006000800011
更新日期:2006-08-01 00:00:00
abstract::This paper reviews the sentences dictated between 1993 and 2002 by the Supreme Courts of Canada and the Unites States, the House of Lords and Supreme Court of the United Kingdom and the European Human Rights Court, about the validity of the legal prohibition of assistance for suicide. These sentences constituted a jud...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
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更新日期:2016-04-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::Andrés Bello, a Venezuelan intellectual arrived in Chile in 1829. He had a decisive influence on the development of natural sciences and medical sciences in this country. The first formal teaching program in Medicine appeared in 1833, with few students due to the low social prestige of Medicine at that time. The Facul...
journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma is the most frequent primary tumor of the liver. It is associated to chronic liver diseases and has a high prevalence in some regions of Africa and Asia. AIM:To describe the clinical characteristics of patients with hepatocellular carcinoma, admitted to two hospitals of the IX regio...
journal_title:Revista medica de Chile
pub_type: 杂志文章,多中心研究
doi:
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Autologous hematopoietic cell transplantation (THA) in patients with multiple myeloma and amyloidosis is the standard of care to promote disease free survival and quality of life. AIM:To report our experience with THA in patients with multiple myeloma. MATERIAL AND METHODS:Retrospective review of the hemat...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014001200001
更新日期:2014-12-01 00:00:00
abstract::The practice of Medicine is exposed to everyday's ethical ventures that, even though not fundamental in a philosophical scope, are most crucial given its incidence and consequences to accessibility and equity in health care. A very special perception must emerge to allow us looking for those situations where moral con...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Noncardiogenic pulmonary edema is a well recognized complication of upper airway obstruction. We report the case of a previously healthy 18-year-old male who presented this complication following laryngospasm after anesthesia. He developed severe pulmonary edema with hypoxemia, high cardiac output and low pulmonary ca...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract::Cerebral vasodilators (CVD) account for 1.6% of the annual expenditure on drugs in Chile. Two kinds are typified: what we have called orthodox CVD and calcium-channel blockers. They have two main uses in neurology: firstly, in acute ischaemic stroke where orthodox CVD (buflomedil, codergocrine mesylate, and nicergolin...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND:Chromosome aberrations (CA) are the main etiology of multiple congenital malformations, recurrent abortions and intellectual disability (ID) specifically of moderate and severe degree. They account for 0.3 to 1% of newborns (NB) and 6 of 10,000 NB have chromosome imbalances with submicroscopic deletions or d...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000300003
更新日期:2011-03-01 00:00:00
abstract::We performed cerebral biopsy in 4 patients with AIDS and evidence of expanding intracerebral lesions. Three patients had cerebral toxoplasmosis and the fourth had Chagas encephalitis. No patient developed complications. We feel that cerebral biopsy is warranted and safe in patients with AIDS and intracerebral lesions ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND:99mTc-sestamibi parathyroid SPECT scintigraphy is a useful tool in the pre-operative study of hyperparathyroidism. False negatives (FN) have been reported in 5.7-14% of the examinations. AIM:To characterize 99mTc-sestamibi FN in cases referred for primary hyperparathyroidism (PHP) to a university hospital. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The implementation of the marketing strategies in public hospitals provides management advantages and improves the relationship between customers and staff. AIM:To analyze the application of marketing strategies in a public hospital, from the perspective of the staff. MATERIAL AND METHODS:A structured surv...
journal_title:Revista medica de Chile
pub_type: 杂志文章
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更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Evaluation of 24-hour collection accuracy is based on urinary creatinine excretion (UCr), usually using wide ranges indexed by weight. Equations that predict the expected UCr are also available. AIM:To generate an equation for estimating UCr in Chilean population and evaluate its performance in comparison t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872020000600734
更新日期:2020-06-01 00:00:00