[A new equation to predict urine creatinine values using data from Chilean population].

Abstract:

BACKGROUND:Evaluation of 24-hour collection accuracy is based on urinary creatinine excretion (UCr), usually using wide ranges indexed by weight. Equations that predict the expected UCr are also available. AIM:To generate an equation for estimating UCr in Chilean population and evaluate its performance in comparison to existing formulas. MATERIAL AND METHODS:A total of 464 24-hour urine collections from outpatients aged between 15 and 88 years old were used. Ninety percent of collections (n = 418) were randomly extracted to assess the association between absolute UCr values with sex, age, height and weight of participants. A formula was created to estimate the 24-hour UCr using a multiple linear regression model. In the remaining 10% of urine collections (n = 46), the performance of this formula and others reported in the literature were tested. RESULTS:Age, sex and weight were significantly associated with 24-hour UCr values. The new equation was able to predict UCr values with a similar accuracy than CKD-EPI and Walser equations and outperformed other equations. CONCLUSIONS:Our equation developed with Chilean values predicts 24-hour UCr values accurately.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Huidobro Espinosa JP,Sepúlveda RA,Muñoz GM

doi

10.4067/S0034-98872020000600734

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

734-739

issue

6

eissn

0034-9887

issn

0717-6163

pii

S0034-98872020000600734

journal_volume

148

pub_type

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