Abstract:
BACKGROUND:Systemic vasculitis are a group of heterogeneous diseases characterized by inflammation and necrosis of blood vessel walls. The etiology is not known, but geographic and environmental factors are implicated. AIM:To describe the clinical features of microscopic polyangiitis (MPA) and Wegener's granulomatosis (WG) in a Chilean cohort of patients. PATIENTS AND METHODS:Retrospective review of the medical records of 123 patients with the diagnosis of systemic vasculitis (65 MPA and 58 WG), seen from 1990 to 2001. The diagnosis were made based on the American College of Rheumatology and Chapel Hill criteria. RESULTS:The mean follow-up for MPA was 15 months (1-120) and for WG, 20 months (1-120). The median age (years) at diagnosis for MPA was 61 (19-82) and WG 50 (20-82). Gender distribution was similar in both groups (male: 68% and 57% respectively). The main clinical features in the MPA group were renal involvement (68%), peripheral nervous system involvement (57%), pulmonary hemorrhage (28%), and skin disease (32%). In the WG group were alveolar hemorrhage (62%), renal involvement (78%), paranasal sinus involvement (57%), and ocular disease (26%). In both, creatinine levels above 2.0 mg/dl were associated with a higher mortality (p< 0.01). ANCA by immunofluorescence was performed in 56 MPA patients (75% had pANCA, 4% had cANCA and 21% were ANCA negative) and in 55 WG patients (17% had pANCA, 79% had cANCA and 4% were ANCA negative). Global mortality was 18% and 17% respectively, and the most common causes of death were infections. CONCLUSIONS:The clinical features of our patients are similar to other published data. In our WG and MPA patients the main predictor for death was a serum creatinine above 2 mg/dl.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Cisternas M,Soto L,Jacobelli S,Marinovic MA,Vargas A,Sobarzo E,Saavedra J,Chauan K,Meléndez G,Foster C,Pacheco D,Wainstein E,Grupo de estudio de las vasculitis, Sociedad Chilena de Reumatología.doi
10.4067/s0034-98872005000300001subject
Has Abstractpub_date
2005-03-01 00:00:00pages
273-8issue
3eissn
0034-9887issn
0717-6163pii
S0034-98872005000300001journal_volume
133pub_type
杂志文章abstract::This paper presents recommendations on the care of HIV infected adults based upon the authors' personal experience with close to 700 patients in a multiprofessional pilot center. This medical care has 5 main objectives: 1) Promotion of good health (through standard recommendation of hygiene, health habits and regular ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:Nasal continuous positive airway pressure therapy (CPAP) in the treatment of choice for adult obstructive sleep apnea (OSA). The diagnosis is established with polysomnography, but this study is expensive and must be repeated in those patients that require CPAP, to titrate the pressure of the therapy. Split p...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006001100004
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:The current recommendations for treatment of patients with newly diagnosed acute promyelocytic leukemia (APL) include all-trans-retinoic acid (ATRA) and anthracycline based chemotherapy. AIM:To evaluate the results of the Chilean protocol following the LPA99 regimen of the Spanish PETHEMA group, except for ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872013001000001
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Recent data suggest an increase in tuberculosis (TB) incidence in Chile. AIM:To evaluate recent epidemiological trends, geographic extension and potential factors associated with TB reemergence in Chile. MATERIAL AND METHODS:Data analysis from official sources and trend analysis. RESULTS:TB incidence rate...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000801042
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:The six minute walk test (6MWT) is an important physical performance measure used in older people. AIM:To assess the total distance walked and the physiological cost of the 6MWT in non-disabled older people. MATERIAL AND METHODS:Fifty six females aged 69 ± 5 years with a body mass index (BMI) of 31 ± 4 kg/...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872015000400010
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Handgrip strength is an important predictor of functional performance among older adults. AIM:To measure handgrip strength in older adults and relate its values to their clinical functional assessment. MATERIAL AND METHODS:Handgrip strength was measured in 1047 older adults living in the community and aged...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872016000500007
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:The restless legs syndrome (RLS) is a movement disorder characterized by an imperative urge to move the legs, associated with paraesthesias, motor restlessness and worsening of symptoms at night with at least partial relief by activity. Its prevalence ranges between 2-15% of general adult population and 20-3...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:In a rapidly changing culture like ours, with emphasis on productivity, there is a strong need to find the meaning of health care work using learning instances that privilege reflection and face to face contact with others. The Diploma in Health and Humanization (DSH), was developed as an interdisciplinary s...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872015000300008
更新日期:2015-03-01 00:00:00
abstract::Atherosclerosis is a systemic disease that may involve more than one territory. Myocardial infarction can occur after carotid endarterectomy and stroke is a well documented morbidity of coronary artery bypass grafting. To optimize results, we have performed concomitant carotid endarterectomy and myocardial revasculari...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::We report a 50-year-old woman with a recent myocardial infarction in whom a myocardial perfusion single photon emission computed tomography (SPECT) with Thallium201 was done simultaneously with a F18-fluorodeoxyglucose (FDG) SPECT to study glucose metabolism. Myocardial infarction was located in the anteroseptal and a...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::One of the main challenges in environmental management is to prevent the public health impact of projects that can cause pollution. To tackle this problem, the new Chilean bill on environmental management has defined the need to determine the potential health risks of a given Project. This paper gives a summary of the...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872011000800015
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Intrahepatic cholestasis of pregnancy (ICP) is a disease of unknown cause characterized by pruritus and biochemical cholestasis in the 3rd trimester of pregnancy. Its pathogenesis may be due to the interaction of abnormalities in the metabolism of estrogens and progesterone, while still unknown environmental...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::We surveyed 605 households selected by conglomerate random sampling in a typical Chilean city in order to study patterns of utilization of medicinal agents. The critical item investigated drug use in the week preceding the interview. The 95% confidence limits for drug utilization were 24.1 and 26.8% and for medicinal ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:Recent studies in mice have demonstrated that the Msx-1 homebox gene is implicated in cleft palate. Thus, it has been suggested that its human homologue, MSX1 (HOX-7), located in chromosome 4 could be involved in the etiology of non syndromic cleft lip palate. AIM:To study the linkage between non syndromic ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract::The rapid development of molecular biology techniques as well as recent progress in the understanding of genetic and molecular basis of human diseases have had enormous impact in the practice of clinical pathology. Since new diagnostic (molecular) tools are now available, the concept of Molecular Pathology is emerging...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2001-07-01 00:00:00
abstract::Ultrasound is a sensible and specific method for the diagnosis, study of natural course and follow up of medical treatment of gallstones. Thus it is important to specify the concordance between echographic and pathological findings of the gallbladder. Ninety one patients were subjected to an ultrasound gallbladder exa...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:The incidence of morbid obesity is increasing and gastric bypass is the most effective surgical treatment. AIM:To assess the long term results of resection gastric bypass among morbidly obese patients aged less than 18 and over 65 years in terms of weight loss and correction comorbidities. MATERIAL AND MET...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008001000003
更新日期:2008-10-01 00:00:00
abstract::Since the first successful pregnancy from a frozen human oocyte was reported, remarkable technological progress has been made in the area of cryopreservation of human oocytes. We report a successful delivery of two healthy babies after transfer of vitrified-warmed embryos derived from intracytoplasmic sperm injection ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000300017
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Measuring the carbon footprint (CF) makes it possible to estimate the contribution of clinical activity to global warming. AIM:To measure the emitter components of CO2 equivalents (CO2e) at the Hospital Base, Puerto Montt (HBPM). MATERIAL AND METHODS:Descriptive study with data collected retrospectively be...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018001201384
更新日期:2018-12-01 00:00:00
abstract::Medical specialization has brought about the need to guarantee suitability for its practice. The progressive changes in knowledge and the incorporation of specific technologies, set forth the need to periodically demonstrate this capacity. In developed countries different initiatives, that sooner or later will become ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::This is the conference given by Jorge Mardones, Emeritus Professor of the University of Chile on the occasion of receiving the Juvenal Hernández award. A biographical trace of Professor Mardones scientific career and its motivations, including his relation to outstanding Chilean scientists is included. A remembrance o...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::Quality has a central role in medical care. The satisfaction of the rights of people to medical care, presupposes good quality medical acts. The meaning of quality goes further than a good attention based on scientific evidence and with competent skills. It comprises patient-physician relationship where professional b...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract::Gabriel Cano de Aponte was Governor of Chile since 1717 and until his death in 1733, being 68 years old. As a soldier, he was an experienced horse rider. The sequence of events that caused his death three months after an equestrian accident is unclear. A systematic clinical analysis of the latter is the main objective...
journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:/S0034-98872008000900020
更新日期:2008-09-01 00:00:00
abstract::Physicians took part in the promotion of public policies that regulated urban and architectural work, before engineers, architects, planners, and even before the State had a chance to take part in the formulation of such policies. Starting in the late nineteenth century, and especially during the first decade of the t...
journal_title:Revista medica de Chile
pub_type: 历史文章,杂志文章
doi:10.4067/S0034-98872016000100015
更新日期:2016-01-01 00:00:00
abstract::This article reports verbatim the National Development Plan for 1978-1983, issued by the Office of the President of the Chilean Republic, and by the Office of National Planning. The document states that an increase in population would be desirable; however, action toward such goal is to be taken by individual couples...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1979-06-01 00:00:00
abstract::This paper undertakes an analysis of the scientific criteria used in the diagnosis of death and underscores the importance of intellectual rigor in the definition of medical concepts, particularly regarding such a critical issue as the diagnosis of death. Under the cardiorespiratory criterion, death is defined as "the...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872004000100015
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Evolutionary theory has contributed with physiological, psychological and behavioral explanations to the comprehension and treatment of eating disorders (ED). The aim of this review is to analyze the relationship between ED and the attachment theory and natural selection based hypotheses (famine flight, repr...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872012000400015
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Obstructive sleep apnea syndrome (OSA) is an important cause of morbidity and mortality in adults. AIM:To evaluate the diagnostic value of clinical features and oximetric data to screen for obstructive sleep apnea before performing polysomnograpy or respiratory polygraphy. MATERIAL AND METHODS:We studied 3...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010000800001
更新日期:2010-08-01 00:00:00
abstract::Inflammatory bowel disease (IBD) is a prevalent chronic disorder, often diagnosed during childhood. Studies have suggested that the incidence of IBD in this group of patients is increasing. Children and adolescents with IBD frequently have more extensive and severe disease than adults. Transition is an important conce...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872015000600010
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Recent studies have described a high percentage of small intestinal bacterial overgrowth (SIBO) in patients with irritable bowel syndrome (IBS). However, the prevalence of SIBO has not been well established in other functional disorders. AIM:To evaluate the prevalence of SIBO in patients with different func...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872007001000003
更新日期:2007-10-01 00:00:00