[Restless legs syndrome: a clinical study in adult general population and in uremic patients].

Abstract:

BACKGROUND:The restless legs syndrome (RLS) is a movement disorder characterized by an imperative urge to move the legs, associated with paraesthesias, motor restlessness and worsening of symptoms at night with at least partial relief by activity. Its prevalence ranges between 2-15% of general adult population and 20-30% of uremic patients. AIM:To evaluate the frequency and the clinical features of RLS in a sample of general adult population and in uremic patients, in Chile, correlating it with biochemical parameters. METHOD:100 relatives of outpatients and 166 uremic patients undergoing chronic haemodialysis were interviewed assessing the presence and severity of RLS according to current diagnostic criteria. Biochemical parameters assessed were hematocrit, serum ferritin, phosphate, intact parathyroid hormone (iPTH) levels. RESULTS:13% of the general population sample was affected, 15% of them were severe. Forty three cases were found among uremic patients (25.9%) (p < 0.01 vs general population), 60% of them were severe and women were affected with higher frequency (p < 0.05) and severity (p < 0.01). Four patients presented RLS even during hemodialysis. No correlation was found with biochemical parameters. Most RLS cases had not been diagnosed previously. CONCLUSIONS:In our population RLS is common and undetected. It is especially prevalent and severe in uremic patients: we found no evidence that anaemia, iron deficiency or iPTH level play a major pathogenic role. Our findings emphasize the need of greater medical awareness of RLS because available therapy may improve the quality of life.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Miranda M,Araya F,Castillo JL,Durán C,González F,Arís L

subject

Has Abstract

pub_date

2001-02-01 00:00:00

pages

179-86

issue

2

eissn

0034-9887

issn

0717-6163

journal_volume

129

pub_type

杂志文章
  • [Molecular genetic study of a severe growth hormone deficiency in a Chilean family].

    abstract::The first and so far the only form of isolated growth hormone deficiency to accede to molecular genetic analysis is IGHD 1A, which has an autosomal recessive mode of inheritance. Several sizes of growth hormone gene deletions, ranging from 6.7 to 8.5 Kb are responsible for IGHD 1A. It has been reported that children w...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Aguirre E,Benítez R,Youlton R,Carvallo P

    更新日期:1993-09-01 00:00:00

  • [DSM-5: the definitive inclusion of psychiatry in medicine?]

    abstract::DSM-5 is a significant factor in promoting the "remedicalization" of psychiatry as the focus of psychiatric knowledge, developed by the evidence-based medicine movement, shifted from the clinically-based biopsychosocial model to a research-based medical model. DSM-5 purposes are 1]clinical: diagnosis, prevention, earl...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872019000400475

    authors: Figueroa G

    更新日期:2019-04-01 00:00:00

  • [Association between chronic periodontitis and rheumatoid arthritis. A systematic review].

    abstract::Rheumatoid arthritis (RA) and chronic periodontitis (CP) may be related due to a bidirectional etiology. The evidence shows that CP could alter the clinical course of RA. We performed a systematic search to determine if CP alters the morbidity of RA, analyzing its clinical and molecular aspects. Of 552 initial article...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872019000600762

    authors: Wen S,Beltrán V,Chaparro A,Espinoza F,Riedemann JP

    更新日期:2019-06-01 00:00:00

  • [Medical leave in hospital personnel].

    abstract::We investigated medical leaves of personnel at Temuco's hospital from 1986 to 1987. 57% of persons had at least one leave and 54% of these had 2 or more leaves. Women and paramedicals had more medical leaves. Most absences occurred in june, july, august (p less than 0.01). Most leaves were caused by respiratory diseas...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Silva CG,Baechler R

    更新日期:1989-07-01 00:00:00

  • [Comparison of Shigella susceptibility to commonly used antimicrobials in the Temuco Regional Hospital, Chile 1990 - 2001].

    abstract:BACKGROUND:The permanent surveillance of antimicrobial susceptibility of Shigella sp in the Temuco Regional Hospital, allowed us to define the empirical use of antimicrobials in dysenteric syndrome. AIM:To study antimicrobial susceptibility of Shigella strains collected from 1997 to May 2001 and compare the results wi...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Boehme C,Iglesias T,Loyola A,Soto L,Rodríguez G,Reydet P,Illesca V

    更新日期:2002-09-01 00:00:00

  • [Fascioliasis in populations of rural areas with high prevalence of animal infection].

    abstract::Between January 1986 and December 1990 the prevalence of F. hepatica infection was studied in 5861 rural inhabitants of the provinces of Curico, Talca and Linares, VII Region, an hyperendemic zone of animal fascioliasis. Every one was screened by intradermal (IDR), complement fixation (CF), double diffusion (DD) count...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Apt W,Aguilera X,Vega F,Zulantay I,Retamal C,Apt P,Sandoval J

    更新日期:1992-06-01 00:00:00

  • [Effectiveness of oral hypoglycemic drugs in the metabolic control of patients with gestational diabetes].

    abstract::Gestational Diabetes is characterized by different degrees of glucose intolerance that produce a series of fetal and perinatal alterations. During many years, in those cases of gestational diabetes that did not respond to nutritional interventions, the use of insulin was a proven treatment to achieve metabolic control...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:/S0034-98872008000700015

    authors: Valdés R E,Soto-Chacón E,Lahsen M R,Barrera H C,Candía P P

    更新日期:2008-07-01 00:00:00

  • [Digoxin is effective in th treatment of patients with heart failure and sinus rhythm].

    abstract::Due to differences in treatment effect in studies on the effectiveness of digoxin in patients with congestive heart failure in sinus rhythm, a cross-over placebo-controlled, randomized double blind clinical trial was performed. Thirty one patients, without previous treatment with digoxin, in New York Heart Association...

    journal_title:Revista medica de Chile

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Lanas F,Standen D,Steinmann WC,Montecinos A,Stockins B

    更新日期:1994-10-01 00:00:00

  • [A workshop to improve written communication skills of medical students].

    abstract:BACKGROUND:Despite being among the best academically prepared of the country, many medical students have difficulties to communicate in writing. In 2005, the School of Medicine at the Pontificia Universidad Católica de Chile introduced a writing workshop in the undergraduate curriculum, to enhance the students' writing...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872009000500004

    authors: Bitran M,Zúñiga D,Flotts P,Padilla O,Moreno R

    更新日期:2009-05-01 00:00:00

  • [Ectopic or migrating spleen and supernumerary spleens: detection and identification with 99mTc, 51Cr and 113In radioisotopes].

    abstract::Congenital malformations of the spleen are rare. We report a patient with an ectopic spleen located in the left iliac fossa, which was excised in order to prevent severe complications such as torsion of the pedicle, rupture or infection. A second patient with idiopathic thrombocytopenic purpura presented with an acces...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Etcheverry R,Allamand JP,Guzmán G,Robinson MI

    更新日期:1989-12-01 00:00:00

  • [International policies towards sick leave: A referent to analyze the Chilean situation].

    abstract::This is a comparative review of sick leave and wage replacement policies among countries of the Organization for Economic Co-operation and Development (EOCD), an organism that Chile joined recently. This review also deals with the main transformations applied to the system to improve its effciency and the variables th...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:/S0034-98872011000400013

    authors: Vergara M

    更新日期:2011-04-01 00:00:00

  • [Glucotoxicity and lipotoxicity: factors in the pathogenesis and evolution of type 2 diabetes].

    abstract::Glucose toxicity refers to the structural and functional damage in the beta cells and target tissues of insulin, caused by chronic hyperglycemia. These alterations cause a lower hormonal secretion and action (insulin resistance). Lipid toxicity refers to the damage caused by persistently high free fatty acid levels, a...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Durruty P,García de los Ríos M

    更新日期:2001-06-01 00:00:00

  • [Bone metastases of a gallbladder carcinoma detected by positron emission tomography/computed tomography: Case report].

    abstract::Signet ring gallbladder carcinoma is a rare aggressive variant of mucinous adenocarcinoma with poor prognosis. Positron emission tomography/computed tomography (PET/CT) with Fluor18 deoxyglucose (F18-FDG) is a useful tool in the staging of gallbladder cancer. We report a 68 years old man with a surgically resected acu...

    journal_title:Revista medica de Chile

    pub_type:

    doi:10.4067/S0034-98872017000400013

    authors: Humeres P,González P,González J,Prado E,Hiplan E

    更新日期:2017-04-01 00:00:00

  • [A scientometric radiography of Revista Médica de Chile].

    abstract::In the context of a festschrift to commemorate the 125th anniversary of the Revista Médica de Chile, "radiography" of the journal has been depicted using several scientometric indicators. Among the mainstream journals in the category of Medicine, General & Internal and taking into account the wide editorial coverage a...

    journal_title:Revista medica de Chile

    pub_type: 历史文章,杂志文章

    doi:

    authors: Krauskopf M

    更新日期:1997-07-01 00:00:00

  • [Primary hyperthyroidism after excision of a Struma ovarii].

    abstract::Struma ovarii is a teratoma composed of thyroid tissue and can be a rare cause of hyperthyroidism. We report a 35 years old woman with a left ovarian mass whose pathology revealed a Struma ovarii. This tumor was partially excised initially to avoid fertility problems and after a successful gestation, the tumor was com...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Sapunar J,Roa JC,Meissner A

    更新日期:2003-07-01 00:00:00

  • [Concentration of cefotaxime in the exudate from ischemic ulcer after systemic and regional administration].

    abstract::We evaluated the concentration of cefotaxime in the exudate from ischemic leg ulcers in 9 subjects with severe obstructive arterial disease. The administration of the drug was either systemic (1 g in 250 ml of saline given in 30 min) or regional at a vein of the foot while a tourniquet was applied at the level of the ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Acevedo A,Schoop W

    更新日期:1990-03-01 00:00:00

  • [Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units].

    abstract::Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, these new therapies, along with greater patient survival, are associated with an increase in untoward effects, particularly in the cardiovascular system. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/s0034-98872018000100068

    authors: Hameau R,Gabrielli L,Garrido M,Guzmán AM,Retamal I,Vacarezza MJ,Greig D,Ocqueteau M,Sánchez C,Pizarro M,Corvalán A,Lavandero S,Castro PF,Martínez G

    更新日期:2018-01-01 00:00:00

  • [Environmental risk factors in the development and evolution of inflammatory bowel disease].

    abstract::Environmental factors may influence the development of Inflammatory Bowel Disease and modify its natural history. The objective of this review is to evaluate current evidence about environmental factors associated with the disease. A better knowledge about the pathogenesis of the disease can lead to better treatment s...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/s0034-98872019000200212

    authors: Meligrana NE,Quera R,Figueroa C,Ibáñez P,Lubascher J,Kronberg U,Flores L,Simian D

    更新日期:2019-02-01 00:00:00

  • [The etiopathogenesis of the acute stress ulcer. The role of oxygen free radicals].

    abstract::We evaluated the role of oxygen free radicals in the induction of acute stress gastric ulcer in rats. After 12 hr of immobility, ulcers of up to 4 mm were observed in the gastric mucosa. Pretreatment with allopurinol, a xanthine oxidase inhibitor, produced a significant reduction in the number and size of lesions (p <...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Mancinelli S,de la Fuente G,Manríquez V,Aracena M,Múñoz R,Mancinelli S,Múñoz S

    更新日期:1990-09-01 00:00:00

  • [Scientific research: a cultural legacy].

    abstract::This is the conference given by Jorge Mardones, Emeritus Professor of the University of Chile on the occasion of receiving the Juvenal Hernández award. A biographical trace of Professor Mardones scientific career and its motivations, including his relation to outstanding Chilean scientists is included. A remembrance o...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Mardones J

    更新日期:1989-02-01 00:00:00

  • [Anterior cervical bronchogenic cyst simulating a thyroid lesion. Report of case].

    abstract::Bronchogenic cysts are congenital malformations of the tracheo-bronchial tree usually located intrathoraxically. We report a 44 years old male with a bronchogenic cyst located exceptionally in the pre tracheal anterior cervical region, simulating a thyroid lesion. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Majlis S,Horvath E,Castro L,Martínez V

    更新日期:1999-08-01 00:00:00

  • [Use of drugs in a urban population].

    abstract::We surveyed 605 households selected by conglomerate random sampling in a typical Chilean city in order to study patterns of utilization of medicinal agents. The critical item investigated drug use in the week preceding the interview. The 95% confidence limits for drug utilization were 24.1 and 26.8% and for medicinal ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Danhier A,Brieva J,Villegas G,Yates T,Pérez H,Boggiano G

    更新日期:1991-03-01 00:00:00

  • [Hemoptysis as the initial manifestation of Behçet's disease. Report of two cases].

    abstract::Arterial involvement in Behçet's disease (BD) is less common than venous lesions. The most commonly affected arteries are: the aorta, lower extremity arteries, mesenteric, femoral, coronary, renal, subclavian and pulmonary arteries. The rupture of pulmonary arteries is the main cause of death of patients with EB and t...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872018000400528

    authors: Abarca M,Santamarina M,Vergara C,Vega J

    更新日期:2018-04-01 00:00:00

  • [Contribution of iron of bread to the Chilean diet].

    abstract::The content and bioavailability of iron contained in Chilean bread was studied in a random sample from 301 bakeries. A wet digestion procedure followed by a colorimetric method was used. Iron bioavailability was examined in 9 adult women using the extrinsic radioactive tag method. The iron content of bread was 2.4 +/-...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Peña G,Pizarro F,Hertrampf E

    更新日期:1991-07-01 00:00:00

  • [Laugier-Hunziker syndrome in a patient with Sjögren’s syndrome: Report of one case].

    abstract::Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of lips and buccal mucosa, often accompanied with melanonychia. The main concern with this condition is to rule out other differential diagnosis with systemic repercussions and similar hyperpigmentation patte...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872016000500017

    authors: Fajre X,Aspillaga M,McNab M,Navarrete J,Sanhueza V,Benedetto J

    更新日期:2016-05-01 00:00:00

  • [Accreditation professional degrees and teaching institutions: the case of Chile].

    abstract::Accreditation has acquired special relevance for the habilitation of professional practice, considering the proliferation of teaching institutions, the variety of training programs and the increasing amount of professionals requiring accreditation or revalidation of their titles. The internationalization of profession...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Rosselot E,Mateluna E,Estévez A,Radrigán ME

    更新日期:1998-06-01 00:00:00

  • [Effects of gender and socioeconomic status of older people on the execution of the 6 minute walk test].

    abstract:BACKGROUND:The six minute walk test (6MWT) is an important physical performance measure used in older people. AIM:To assess the total distance walked and the physiological cost of the 6MWT in non-disabled older people. MATERIAL AND METHODS:Fifty six females aged 69 ± 5 years with a body mass index (BMI) of 31 ± 4 kg/...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872015000400010

    authors: Medina PG,Mancilla ES,Muñoz RC,Escobar MC

    更新日期:2015-04-01 00:00:00

  • [Current epidemiological situation of trichinosis in Chile. 1991-2000].

    abstract:BACKGROUND:Human and animal trichinosis has been recorded in Chile since the late XIX century and is irregularly distributed along the country. From high rates of infection in the early 1900, the frequency of this parasitosis in man has progressively decreased. AIM:To describe and discuss the epidemiological situation...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Schenone H,Olea A,Schenone H,Contreras MC,Mercado R,Sandoval L,Pavletic C

    更新日期:2002-03-01 00:00:00

  • [Chronic inflammatory demyelinating polyneuropathy. Report of six cases].

    abstract::Chronic inflammatory demyelinating polyneuropathy is a heterogeneous disease characterized by symmetrical motor and sensitive alterations, absence of tendon reflexes and increased cerebrospinal fluid protein levels. We report 6 patients with the disease, (three males) aged 41 to 70 years old. Four had the classical pr...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Araya P,Fruns M,Silva C,Pedraza L

    更新日期:1996-11-01 00:00:00

  • [KRAS gene mutation in colorectal cancer].

    abstract:BACKGROUND:KRAS oncogene is involved in colorectal carcinogenesis in 22 to 45% of cases. AIM:To determine the frequency, types and distribution of KRAS mutations in colorectal cancer. MATERIAL AND METHODS:KRAS mutations studies were carried out in primary tumors and metastases of colo-rectal cancer from 56 women aged...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872013000900009

    authors: Roa I,Sánchez T,Majlis A,Schalper K

    更新日期:2013-09-01 00:00:00