Abstract:
:Due to differences in treatment effect in studies on the effectiveness of digoxin in patients with congestive heart failure in sinus rhythm, a cross-over placebo-controlled, randomized double blind clinical trial was performed. Thirty one patients, without previous treatment with digoxin, in New York Heart Association (NYHA) functional class II to IV, with a dilated left ventricle and/or ventricular systolic dysfunction were included. Patients received digoxin, adjusted for blood levels, or placebo, during an 8 week period, prior to crossing over to the other treatment for another 8 weeks. The order of treatments was randomly allocated. Outcome measurement were performed at the end of each 8 week period. Digoxin, compared with placebo, improved NYHA class, 6.9% vs 41.4% (p = 0.013) and increased the treadmill exercise time, 406 +/- 204 s vs 484 +/- 185 s (p = 0.003). During the digoxin treatment the left ventricular and systolic diameter was reduced from 52.9 +/- 8.9 to 50.1 +/- 9.7 mm (p = 0.016) and the shortening fraction increased from 21.4 +/- 8.3 to 24.8 +/- 8.1% (p = 0.009). No significant difference was observed in the left ventricular end diastolic diameter (LVED) of the left ventricle and in a estimation of quality of life. In conclusion, digoxin treatment produced a significant improvement in functional capacity, exercise time, and left ventricular performance.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Lanas F,Standen D,Steinmann WC,Montecinos A,Stockins Bsubject
Has Abstractpub_date
1994-10-01 00:00:00pages
1147-52issue
10eissn
0034-9887issn
0717-6163journal_volume
122pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:Quality of life and psychological well-being are readily hampered by depression. The changes that students face during college life impact their psychological health and well-being, including the emergence of mental health problems like depression Aim: To determine the relationship between depressive symptom...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000500579
更新日期:2019-05-01 00:00:00
abstract::The preliminary results of a prospective and cooperative protocol for the treatment of soft tissue sarcomas of trunk and extremities, stages IB-IIIB are presented. Thirty one patients (17 males, 22 with a tumor larger than 5 cm) aged 16 to 68 years, were treated with one dose of epirubicin 70 mg/m2 i.v. and radiothera...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:In Chile, occupational illnesses are defined by the "Work-related accidents and occupational illnesses law". The institutions that administer that law have the legal obligation to determine the "occupational" or "common" origin of accidents and diseases. AIM:To compare symptoms and problems at work in a gro...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011001000019
更新日期:2011-10-01 00:00:00
abstract::The most significant facts in the development of Chilean cardiology since 1930 are reviewed. The preeminence of great clinicians in the thirties was followed by the creation of Departments of Cardiology in University Hospitals. The emergence of powerful diagnostic tools and cardiac surgery allowed an accelerated devel...
journal_title:Revista medica de Chile
pub_type: 历史文章,杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::One of the main challenges in environmental management is to prevent the public health impact of projects that can cause pollution. To tackle this problem, the new Chilean bill on environmental management has defined the need to determine the potential health risks of a given Project. This paper gives a summary of the...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872011000800015
更新日期:2011-08-01 00:00:00
abstract::Constrictive Pericarditis (CP) is an unusual disease. Its most common causes are idiopathic or secondary to cardiac surgery. Less frequently it is caused by connective tissue diseases. We report a 30 years old woman hospitalized due to progressive dyspnea, chest pain and signs of right sided heart failure. During her ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014000800015
更新日期:2014-08-01 00:00:00
abstract::We report a 56 years old male patient presenting with a sympathetic denervation of the right upper limb due to an apical lung cancer. Vasomotor paralysis of the limb was objectively documented with a contact termography. The clinical presentation of this patient was unusual, considering that the alteration occurred wi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:The age at which children born preterm normalize their bone mineral density, is not well known. AIM:To study if children born preterm have normalized their bone mineral density at age 5 to 7 years. PATIENTS AND METHODS:Twenty six infants born preterm (14 male), were studied at age 5 to 7 years. Birth weigh...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract::Accreditation has acquired special relevance for the habilitation of professional practice, considering the proliferation of teaching institutions, the variety of training programs and the increasing amount of professionals requiring accreditation or revalidation of their titles. The internationalization of profession...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract::Approximately 15% of patients with Wolff Parkinson White's syndrome who undergo electrophysiologic study have more than one accessory pathway. We describe the electrophysiologic testing and findings in 2 patients with multiple pathways. Identification of these is highly relevant since successful surgical therapy depen...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract:BACKGROUNDS AND AIMS:Total parenteral nutrition (TPN) has been traditionally used as an adjunctive therapy in severe ulcerative colitis patients. We performed a prospective study to ascertain the safety, nutritional efficiency, tolerance and costs of total enteral nutrition in this situation. METHODS:After 48 hours of...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract::The association of gastric lymphoma and gastric adenocarcinoma in the same patient is uncommon. We report a 76 year-old male with a previous history of massive upper gastrointestinal bleeding who required a subtotal gastrectomy with Billroth II reconstruction in 1974. Pathology demonstrated a gastric lympho-histiocyti...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872008001000013
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Twenty to twenty two percent of work related accidents have a direct or indirect relationship with recent alcohol use. AIM:To detect recent alcohol or drug use in patients who required hospitalization for severe work related accidents. PATIENTS AND METHODS:Blood and urine samples were obtained from patient...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:There is phenotypic and genetic variability among the species Borrelia burgdorferi that produces Lyme disease. Three gene species and seven serotypes have been defined. AIM:To study the efficacy of two gene species in the serological diagnosis of Borrelia burgdorferi infections in Granada, Spain. MATERIAL ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Enterococcus is a bacterial genus with low virulence. However, in the last years, the importance of some enterococcus species as nosocomial pathogens has increased, specially due to their resistance to some antimicrobial. AIM:To identify enterococcus strains using classical biochemical techniques and genomi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The Chilean Ministry of Health developed a healthy lifestyles intervention directed to adults with overweight and cardiovascular risk factors, called "Program on Healthy Eating and Physical Activity" (PASAF). AIM:To evaluate the impact of PASAF on nutritional status and metabolic parameters. PATIENTS AND M...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014000700001
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Women in childbearing ages (WCBA) represent a strategic intervention group to reverse the global trend of increasing obesity. AIM:To conduct a review of studies reporting obesity prevalence in WCBA in Chile in the last 25 years. MATERIAL AND METHODS:To describe obesity prevalence, we used three approaches,...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872014001100011
更新日期:2014-11-01 00:00:00
abstract::Priapism is a rare complication of hematological diseases. Among leukemia, it is most frequently seen in patients with chronic myeloid leukemia, due to the high leukocyte counts that these patients achieve. We report a 22 years old male who presented with a priapism lasting more than 24 hours. Thirty six hours after a...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract::The incidence of hepatitis, mumps, poliomyelitis, scarlet fever, pertussis and measles from 1954 to 1984 was studied from the annual records of infectious diseases. Fluctuations were evaluated by Fourier analysis. Periodic recurrency was detected for poliomyelitis, scarlet fever, pertussis and measles and was likely f...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Rates of obesity reach high levels in Chile, with geographic, social and school variations. AIM:To identify factors at two levels associated with excessive weight in school children: child-family characteristics and school-neighborhood. MATERIAL AND METHODS:Using a cross-sectional and multi-step design, se...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872007001200002
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Psychiatric disorders that appear during childhood or adolescence should be a public health priority. AIM:To report the results of a national representative survey in the Latin American region examining the prevalence of DSM-IV psychiatric disorders in children and adolescents. MATERIAL AND METHODS:Subject...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000400005
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Microbial invasion of amniotic cavity occurs in 30 to 50% of patients with premature membrane rupture. AIM:To determine the outcomes associated with microbial invasion of the amniotic cavity (MIAC) in patients with preterm premature rupture of membrane (pPROM). PATIENTS AND METHODS:One hundred thirty four ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872005000100007
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Free-text imposes a challenge in health data analysis since the lack of structure makes the extraction and integration of information difficult, particularly in the case of massive data. An appropriate machine-interpretation of electronic health records in Chile can unleash knowledge contained in large volum...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872019001001229
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:In 1992, a consensus conference defined the terms systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis and septic shock. Since then, numerous reports have validated the prognostic usefulness of these operative definitions. AIM:To evaluate if sepsis severity criteria, as defined by the Conse...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract::This review examines the evidence about the relationship between dental procedures and the incidence of transient bacteremia. One of the main obstacles was to define "invasive dental procedure" as an indication for antimicrobial prophylaxis for patients with high risk of bacteremia. A search in WorldWideScience and Sc...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872018000700899
更新日期:2018-07-01 00:00:00
abstract::Sepsis from an infected cardiac valve can lead to bacterial seeding and destruction of the arterial wall with formation of a mycotic aneurysm. The natural history of these lesions is the rupture. We report the case of a 20 year old female who was admitted to our institution with massive mitral regurgitation and emboli...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract::Wernicke encephalopathy is considered a complication of dialytic therapy, but there are few reports of this complication. We report a 57 years old man and a 45 years old woman, with grade IV renal failure, who after acute peritoneodialysis and chronic hemodialysis respectively, had a confusional syndrome that responde...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::Preventive measures for teenage pregnancy (TP), would decrease infant mortality, early undernutrition and statal social expenditure. The cost of programs for TP would decrease with a sensitive risk indicator. We searched some pysoshocial and familial parameters, useful to built up this indicator. Self esteem (Piers-Ha...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract::Chronic kidney disease is a worldwide health problem. The incidence and prevalence of kidney failure is in constant increase, involving poor outcomes and high costs. The leading causes of kidney failure are type 2 diabetes and hypertension. The new initiative "Kidney Disease Improving Global Outcomes (KDIGO)" is a glo...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872005000300011
更新日期:2005-03-01 00:00:00
abstract::Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of lips and buccal mucosa, often accompanied with melanonychia. The main concern with this condition is to rule out other differential diagnosis with systemic repercussions and similar hyperpigmentation patte...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872016000500017
更新日期:2016-05-01 00:00:00