[Comparison of Shigella susceptibility to commonly used antimicrobials in the Temuco Regional Hospital, Chile 1990 - 2001].

Abstract:

BACKGROUND:The permanent surveillance of antimicrobial susceptibility of Shigella sp in the Temuco Regional Hospital, allowed us to define the empirical use of antimicrobials in dysenteric syndrome. AIM:To study antimicrobial susceptibility of Shigella strains collected from 1997 to May 2001 and compare the results with those reported in 1990. MATERIAL AND METHODS:Two hundred and seventeen Shigella strains, coming from stool cultures of pediatric patients, were studied. RESULTS:In the period 1989-1990 Shigella flexneri was the main species isolated (83%) whereas, in the period 1997-2001, Shigella sonnei (55.8%) predominated. In the second period, an increase of antimicrobial resistance, as compared with the period 1989-1990, was observed for ampicillin (74.5 and 42% respectively), for cotrimoxazol (57.5 and 45% respectively) and tetracycline (64 and 8% respectively). Chloramphenicol resistance increased from 0 to 57.5%. In the second period no resistance to ciprofloxacin was detected. There was simultaneous resistance to four drugs in 30% of the strains, predominating multiresistance in S flexneri (52.1%). CONCLUSIONS:In the two periods studied, a significant increase was detected in the resistance of Shigella strains to antimicrobials.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Boehme C,Iglesias T,Loyola A,Soto L,Rodríguez G,Reydet P,Illesca V

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

1021-6

issue

9

eissn

0034-9887

issn

0717-6163

journal_volume

130

pub_type

杂志文章
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