[Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units].

Abstract:

:Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, these new therapies, along with greater patient survival, are associated with an increase in untoward effects, particularly in the cardiovascular system. Although cardiotoxicity induced by oncologic treatments affects predominantly the myocardium, it can also involve other structures of the cardiovascular system, becoming one of the main causes of morbidity and mortality in those who survive cancer. The main objective of cardio-oncology is to achieve the maximum benefits of oncologic treatments while minimizing their deleterious cardiovascular effects. It harbors the stratification of patients at risk of cardiotoxicity, the implementation of diagnostic tools (imaging techniques and biomarkers) for early diagnosis, preventive strategies and early treatment options for the complications. Herein, we discuss the basic knowledge for the implementation of cardio-oncology units and their role in the management of cancer patients, the diagnostic tools available to detect cardiotoxicity and the present therapeutic options.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Hameau R,Gabrielli L,Garrido M,Guzmán AM,Retamal I,Vacarezza MJ,Greig D,Ocqueteau M,Sánchez C,Pizarro M,Corvalán A,Lavandero S,Castro PF,Martínez G

doi

10.4067/s0034-98872018000100068

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

68-77

issue

1

eissn

0034-9887

issn

0717-6163

pii

S0034-98872018000100068

journal_volume

146

pub_type

杂志文章,评审
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  • [Contribution of iron of bread to the Chilean diet].

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    pub_type: 历史文章,杂志文章

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  • [Malignant infarct of the middle cerebral artery in a patient with bacterial meningitis].

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  • [Glucotoxicity and lipotoxicity: factors in the pathogenesis and evolution of type 2 diabetes].

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    doi:

    authors: Durruty P,García de los Ríos M

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  • [The Revista Médica de Chile, 100 years ago].

    abstract::The september 1888 issue of the Journal contains an article by Luis Asta-Buruaga MD, "Ambulances in New York: a system to be instituted in Santiago. In addition to encouraging this project, the idea of establishing small hospitals in peripheral quarters of the city is discussed. Dr Asta-Buruaga was a graduate from Col...

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    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Costa-Casaretto C

    更新日期:1989-01-01 00:00:00

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    authors: Valenzuela C,Avendaño A,Huerta J,Wells P,Gana R

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  • [Seasonal patterns of infectious disease: similarity and differences].

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  • [Echotomographic findings in gastric cancer].

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  • [Interferon Lambda 4 RS12979860 C>T polymorphism is not associated with liver fibrosis in patients with hepatitis C].

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