Abstract:
BACKGROUND:Framingham risk score (FRS) has limitations and can underestimate risk. Carotid ultrasound to measure intima media thickness or plaques is recommended for cardiovascular risk assessment. AIM:To determine the prevalence of subclinical atherosclerosis in asymptomatic subjects classified as low and intermediate risk. MATERIAL AND METHODS:Cross-sectional study performed in subjects without cardiovascular disease. Cardiovascular risk was estimated using the Chilean FRS and the General Cardiovascular Disease FRS. Carotid ultrasound was performed in all subjects. We defined subclinical atherosclerosis as the presence of carotid plaque or intima media thickness greater than 75th percentile by gender and age. RESULTS:We studied 203 subjects aged 47.2 ± 9.6 years (54% males). Mean intima media thickness was 0.62 ± 0.1 mm. An abnormal value was detected in 68 subjects (33%) and carotid plaques in 32 subjects (15.7%). Based on Chilean FRS, 96% were considered at low risk, 4% at intermediate, and none at high risk. In the low risk group the prevalence of abnormal intima media thickness and plaques was 40 and 14% respectively. Presence of plaques was more common in women than men (23 and 7% respectively, p < 0.01). According to the General Cardiovascular Disease FRS, 23% were at low, 39% at low intermediate and 28% at high intermediate risk. In the low risk group the prevalence of an abnormal intima media thickness was 34% and no subject had plaques. CONCLUSIONS:Carotid plaques were detected in Chilean subjects classified as having a low FRS risk. The underestimation of risk was higher in Chilean women.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Varleta P,Concepción R,Julio P,Casanova H,Navarrete Cdoi
10.4067/S0034-98872016000100005subject
Has Abstractpub_date
2016-01-01 00:00:00pages
30-8issue
1eissn
0034-9887issn
0717-6163pii
S0034-98872016000100005journal_volume
144pub_type
杂志文章abstract::Low plasma HDL cholesterol levels are an independent risk factor for atherosclerotic cardiovascular disease. During the past years, the study of HDL has been stimulated by the discovery of novel genes and proteins, which have provided new insights into the molecular and cellular mechanisms involved in HDL metabolism. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872005000700011
更新日期:2005-07-01 00:00:00
abstract::We analyze the effect of inspiratory muscle training (IMT) in patients with chronic obstructive pulmonary disease (COPD), with special emphasis on its effects on inspiratory muscle function and clinical outcomes. We reviewed only randomized, controlled studies that have either controlled both the load and the breathin...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1998-05-01 00:00:00
abstract::Microbiology starts in Chile at the end of the XIXth century as part of the effort to develop basic sciences at the University of Chile Medical School. Publications by Vicente Izquierdo on gonorrheae and Alejandro del Río on the organisms of dysenteriae were pioneer works in this area. The field was progressively deve...
journal_title:Revista medica de Chile
pub_type: 历史文章,杂志文章
doi:
更新日期:1992-04-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006000500006
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000800831
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
abstract::In the last decades, there has been an increase in life expectancy in the world, with the consequent modification in the proportion of adults over 60 years. This is accompanied by an increase in pathologies for which aging is the main risk factor, such as dementia and hearing loss, which profoundly affect the quality ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872020000801128
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:In Chile, Thyroid cancer (TC) is included in a list of diseases that have a guaranteed access to treatment, endorsed by the Ministry of Health. The care burden of the disease will depend on its incidence. AIM:To estimate the incidence of TC in Chilean patients with access to thyroid surgery and describe its...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872020000500573
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journal_title:Revista medica de Chile
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更新日期:2000-06-01 00:00:00
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000400005
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:2004-09-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000700823
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000200009
更新日期:2012-02-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 历史文章,杂志文章
doi:
更新日期:1996-04-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
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journal_title:Revista medica de Chile
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doi:
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
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journal_title:Revista medica de Chile
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doi:10.4067/s0034-98872006000800011
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journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872011000300013
更新日期:2011-03-01 00:00:00
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journal_title:Revista medica de Chile
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
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