[Identification of B and F human immunodeficiency virus subtypes in Chilean patients].

Abstract:

BACKGROUND:Type I human immunodeficiency virus (HIV) is characterized by a great genetic variability. There are three groups of virus throughout the world: O, N and M. Group M is responsible for AIDS pandemic and is subdivided in 9 genetic subtypes. Most viral strains in South America are subtype B. AIM:To determine the frequency of HIV subtypes in Chilean patients. MATERIAL AND METHODS:Genetic analysis of C2-V3-C3 region of the gene env in HIV strains coming from 77 Chilean subjects infected by different means. DNA heteroduplex mobility assay was used to determine HIV subtypes. RESULTS:Sixty eight cases were infected with subtype B (88.3%) and nine cases were infected with subtype F (11.7%). CONCLUSIONS:Subtype B is the predominant HIV in Chile, but subtype F is also present.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Ríos M,Villanueva C,San Martín C,Ramírez E

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

711-8

issue

7

eissn

0034-9887

issn

0717-6163

journal_volume

131

pub_type

杂志文章
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