[Treatment results of early breast cancer: a retrospective review].

Abstract:

BACKGROUND:Breast cancer will develop in one out of ten women during their lifetime. Early diagnosis has increased in recent years. AIM:To describe a population of women with breast cancer stage T1N0M0. To analyze radiation therapy toxicity and to evaluate treatment results. MATERIAL AND METHODS:Retrospective review of the medical records of 125 women (aged 35 to 80 years) with breast cancer T1N0M0, that were treated between January 1997 and May 2004, with breast conserving surgery and postoperative radiation therapy at an oncology center. Patients lost from follow up were contacted by telephone. RESULTS:An abnormal screening mammography was the reason for consult in 62% of cases. The average tumor size was 11.6 mm. Tumors detected with screening mammogram were smaller than those detected on physical exam. The most common radiotherapy toxicity was erithema, which was severe in 2.5% of cases. No patient had to stop the radiation treatment due to toxicity. One patient developed arm edema. Tamoxifen was prescribed for 5 years to 80% of patients and 17 patients received chemotherapy. After an average follow up of 40 months, no patient has developed local breast relapse, three patients developed contralateral breast cancer and three developed distant metastasis. Two patients died from breast cancer. Disease free survival was 95%. CONCLUSIONS:Radiotherapy was well tolerated and had excellent local control. Screening mammography detects small tumors. Survival is excellent for early stage breast cancer.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Sánchez C,Bustos M,Camus M,Alvarez M,Goñi I,León A,Besa de C P

doi

10.4067/s0034-98872007000400003

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

427-35

issue

4

eissn

0034-9887

issn

0717-6163

pii

S0034-98872007000400003

journal_volume

135

pub_type

杂志文章
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  • [Application of a system of serological surveillance of Chagas disease in a region of high chagasic endemia. I. Prevalence of Trypanosoma cruzi infection in Salamanca].

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    authors: Donoso H,Osorio J

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  • [Appendectomies for suspected acute appendicitis during pregnancy: experience at a Chilean public hospital].

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  • [Synchronous tumors detected with contrast-enhanced F18-FDG positron emission tomography/computed tomography (PET/CTc) in colorectal cancer].

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    abstract::Background The treatment of choice of newly diagnosed multiple myeloma (NDMM) is an induction with proteasome inhibitors followed autologous stem cell transplantation (HSCT). Since 2013, the treatment of these patients in the public system is based on CTD (cyclophosphamide, thalidomide, and dexamethasone). Aim To eval...

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  • [Immunophenotyping of peripheral blood lymphocytes from Chilean chronic chagasic patients by flow cytometry].

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    authors: Sánchez G,Zulantay I,Gajardo M,Venegas J,Villanueva R,Pérez A,Liendo F,Apt W,Solari A

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  • [Spontaneous bacterial peritonitis: a frequent and recurrent complication in cirrhotic patients with ascites].

    abstract::One hundred and twenty consecutive patients with liver cirrhosis and ascites were prospectively studied in order to analyze the frequency, clinical and bacteriological features, recurrence, and prognosis of spontaneous bacterial peritonitis (SBP). Two variants of SBP were defined: culture positive SBP and culture nega...

    journal_title:Revista medica de Chile

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    authors: Chesta J,Brahm J,Poniachik J,Latorre R,Hurtado C,Novoa X,Velasco M

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  • [Renal artery thrombosis after withdrawal from anticoagulation therapy in a kidney transplant recipient with thrombophilia: report of one case].

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    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000100014

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  • [Cell differentiation of cultured mammary epithelium].

    abstract::The functional differentiation of mammary epithelial cells requires specific hormones, growth factors and chemical signals of the cellular environment. These signals consist in cell communication with the extracellular matrix and cell-cell interactions which through an intrincated mechanism lead to the events that tri...

    journal_title:Revista medica de Chile

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    doi:

    authors: Cornejo R,Rocha H

    更新日期:1996-04-01 00:00:00

  • [Myeloid sarcoma: report of one case with trisomy 11].

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    更新日期:2011-07-01 00:00:00

  • [Tuberculosis and diabetes mellitus: a longitudinal-retrospective study in a teaching hospital].

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    journal_title:Revista medica de Chile

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    doi:

    authors: Olmos P,Donoso J,Rojas N,Landeros P,Schurmann R,Retamal G,Meza M,Martinez C

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