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[Predictive value of clinical features and nocturnal oximetry for the detection of obstructive sleep apnea syndrome].

Abstract：

BACKGROUND:Obstructive sleep apnea syndrome (OSA) is an important cause of morbidity and mortality in adults. AIM:To evaluate the diagnostic value of clinical features and oximetric data to screen for obstructive sleep apnea before performing polysomnograpy or respiratory polygraphy. MATERIAL AND METHODS:We studied 328 consecutive adult patients referred for snoring or excessive daytime sleepiness to a sleep clinic in whom a standardized questionnaire and the Sleepiness Epworth Scale were performed and body mass index (BMI), cervical circumference (CC), and nocturnal oximetry were measured. RESULTS:Fifty three percent (n = 173) had evidence of clinically significant OSA (apnea/hypopnea index (AHI) > 15 events/h). Patients with OSA were more likely to be male, obese (BMI ≥ 26 kg/m²), smokers, to have a thick neck (CC > 41 cm), and to have a significant greater prevalence of relative reported apneas and excessive daytime sleepiness, as determined by Epworth scale. Male gender (Odds ratio (OR): 4.00; 95% confidence intervals (CI): 1.59-10.0, p = 0.003), BMI ≥ 26 kg/m² (OR: 3.68; 95%CI: 1.59-8.49, p = 0.002), smoking (OR: 2.29; 95% CI: 1.17-4.47, p = 0.015), Epworth index > 13 (OR: 2.65; 95% CI: 1.35-5.23, p = 0.005) and duration of symptoms over 2 years (OR: 2.35; 95% CI: 1.20-4.58, p = 0.012) were significant independent predictors of OSA. In nocturnal oximetry, the lowest SpO2 (SpO2 min) and the length of registries below 90% (CT-90) were independent predictors of OSA and both correlated significantly with AHI (r = -0.49 and r = 0.46 respectively, p < 0.001). CONCLUSIONS:No single factor was usefully predictive of obstructive sleep apnea. However, combining clinical features and oximetry data may be appropriate to detect clinically significant OSA patients.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Saldías P F,Jorquera A J,Díaz P O

doi

/S0034-98872010000800001

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

941-50

issue

8

eissn

0034-9887

issn

0717-6163

pii

S0034-98872010000800001

journal_volume

138

pub_type

杂志文章

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