[Worsening situation of tuberculosis in Chile].

Abstract:

BACKGROUND:Recent data suggest an increase in tuberculosis (TB) incidence in Chile. AIM:To evaluate recent epidemiological trends, geographic extension and potential factors associated with TB reemergence in Chile. MATERIAL AND METHODS:Data analysis from official sources and trend analysis. RESULTS:TB incidence rate increased from 12.3 (2014) to 14.7 (2017) per 100,000 inhabitants. Morbidity rates also increased in nine out of 15 regions. The proportion of TB cases in specific groups has also increased in the last six years: HIV/AIDS (68%), immigrants (118%), drug users/alcoholics (267%) and homeless people (370%). Several indicators of the national TB program performance have deteriorated including TB case detection, HIV co-infection study and contact tracing activities. Overall results indicate a higher than expected case-fatality ratio (> 3%), high rates of loss from follow-up (> 5%), and low percentage of cohort healing rate (< 90%). This decline is associated with a Control Program with scarce human resources whose central budget decreased by 90% from 2008 to 2014. New molecular diagnostic tools and liquid media culture were only recently implemented. CONCLUSIONS:TB trends and overall program performance indicators have deteriorated in recent years in Chile and several factors appear to be involved. Multiple strategies will be required to rectify this situation.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Fica A,Herrera T,Aguilera X

doi

10.4067/S0034-98872019000801042

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

1042-1052

issue

8

eissn

0034-9887

issn

0717-6163

pii

S0034-98872019000801042

journal_volume

147

pub_type

杂志文章
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  • [Prevalence of sexual dysfunction in climacteric women. Influence of menopause and hormone replace therapy].

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    doi:

    authors: Blümel JE,Araya H,Riquelme R,Castro G,Sánchez F,Gramegna G

    更新日期:2002-10-01 00:00:00

  • [Characteristics of acute myocardial infarction in patients with diabetes mellitus].

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    authors: Kunstmann S,Corbalán R,Rodríguez JA,Casanegra P,Varela ML

    更新日期:1993-06-01 00:00:00

  • [Ecologic dynamics of infectious diseases. II. Periodic recurrence of epidemics].

    abstract::The incidence of hepatitis, mumps, poliomyelitis, scarlet fever, pertussis and measles from 1954 to 1984 was studied from the annual records of infectious diseases. Fluctuations were evaluated by Fourier analysis. Periodic recurrency was detected for poliomyelitis, scarlet fever, pertussis and measles and was likely f...

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    authors: Canals M,Martínez L,Firinguetti L

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  • [Risk markers for insulin-dependent diabetes mellitus and duration of exposure to gluten in celiac patients].

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  • [Legalization of medically assisted death: its potential impact on the development of palliative care].

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    journal_title:Revista medica de Chile

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    更新日期:2008-07-01 00:00:00

  • [Factor analysis and internal consistency of pedagogical practices questionnaire among health care teachers].

    abstract:BACKGROUND:Teaching practice is one of the most complex topics of the training process in medicine and other health care careers. The Teaching Practices Questionnaire (TPQ) evaluates teaching skills. AIM:To assess the factor structure and internal consistency of the Spanish version of the TPP among health care teacher...

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  • [Etiologic diagnosis of pneumonia in HIV-AIDS patients. Usefulness of fibrobronchoscopy].

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    pub_type: 杂志文章

    doi:

    authors: Henríquez A,Srur E,Giglio M,Fernández A,Cona E,Lorca M,García A,Northland R,Segovia J,Gutiérrez S

    更新日期:1993-03-01 00:00:00

  • [Multiplex PCR assay in spinal fluid to identify simultaneously bacterial pathogens associated to acute bacterial meningitis in Chilean children].

    abstract:BACKGROUND:Acute bacterial meningitis (ABM) is a serious disease that needs rapid diagnosis for an accurate treatment. The most important etiological agents are: Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae type b. Overall pathogen detection rate in patients with ABM in Chile is 83%. AIM...

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    authors: Reyes S M,Torres T JP,Prado J V,Vidal A R

    更新日期:2008-03-01 00:00:00

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    doi:

    authors: Oyarzún A,Santos JL,Carrasco E,Albala C,Salinas A,Pérez F

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  • [Constrictive pericarditis as a serious and rare presentation of systemic lupus erythematosus: Report of one case].

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    doi:

    authors: Nazer Herrera J,Cifuentes L,Ruiz G

    更新日期:1993-09-01 00:00:00

  • [The relevance of environmental health and the scope of pediatric environmental health specialty units].

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    journal_title:Revista medica de Chile

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    doi:/S0034-98872009000100016

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  • [HIV infection. Diagnosis in the national network of laboratories in Chile].

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    pub_type: 杂志文章

    doi:

    authors: Sánchez G,Vera L,Soto G,Mora J,Ramírez E

    更新日期:1991-11-01 00:00:00

  • [Recent case law about the right to die].

    abstract::This paper reviews the sentences dictated between 1993 and 2002 by the Supreme Courts of Canada and the Unites States, the House of Lords and Supreme Court of the United Kingdom and the European Human Rights Court, about the validity of the legal prohibition of assistance for suicide. These sentences constituted a jud...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872016000400009

    authors: Bascuñán R A

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  • [Prevalence of calorie protein malnutrition among patients in chronic hemodialysis].

    abstract:BACKGROUND:Malnutrition has been strongly associated with morbidity and mortality in hemodialysis patients. In the other hand, dialysis allows a nutritional improvement in patients with more than 12 months in dialysis. AIM:To study the prevalence of malnutrition among patients in hemodialysis. PATIENTS AND METHODS:We...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

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    authors: Huidobro A,Velasco N,Rojas T

    更新日期:2001-05-01 00:00:00

  • [Frequency of oral squamous cell carcinoma and oral epithelial dysplasia in oral and oropharyngeal mucosa in Chile].

    abstract:BACKGROUND:Oral cancer in Chile corresponds approximately to 1.6% of all cancer cases. There are few studies about oral epithelial dysplasia and oral squamous cell carcinoma in the Chilean population. AIM:To determine the frequency of hyperkeratosis, mild, moderate and severe oral epithelial dysplasia, in situ carcino...

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    authors: Martínez C,Hernández M,Martínez B,Adorno D

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  • [Duffy blood group in malformed newborns and their mothers].

    abstract::The aim of this work is to analyze the distribution of Duffy blood group and the reproductive history of 148 malformed newborns and their mothers compared to 131 control pairs. The mother-child segregation of the system is analyzed using ITO matrixes. A higher frequency of heterozygote mothers for the system was found...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Cifuentes L,Nazer J,Armanet L,Ruiz G,Vargas J

    更新日期:1994-09-01 00:00:00

  • [Potential difference of the gastric mucosa in gastroduodenal disease. Relation with endoscopical and histologic findings].

    abstract::Most studies of gastric transmucosal potential difference concern acute damage. We studied this phenomenon in 168 patients with different pathologic processes: erosive gastritis, duodenal and prepyloric ulcer, atrophic gastritis, gastric ulcer and normal controls. Ag-AgCl electrodes and Agar-KCl bridges were used to r...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Defilippi C,Morales A,Smok G,Angelo S

    更新日期:1989-04-01 00:00:00

  • [Use of drugs in a urban population].

    abstract::We surveyed 605 households selected by conglomerate random sampling in a typical Chilean city in order to study patterns of utilization of medicinal agents. The critical item investigated drug use in the week preceding the interview. The 95% confidence limits for drug utilization were 24.1 and 26.8% and for medicinal ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Danhier A,Brieva J,Villegas G,Yates T,Pérez H,Boggiano G

    更新日期:1991-03-01 00:00:00

  • [Airway tridimensional printing].

    abstract::Tridimensional printing is becoming relevant in medicine, specially in surgical and interventional specialties. We review the technical aspects and clinical application of airway tridimensional printing. Using this technique, simulation models for bronchoscopy and models for diagnostic and therapeutic procedures such ...

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    pub_type: 杂志文章,评审

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  • [Cephalosporins: bacterial resistance measured by penicillin-binding proteins].

    abstract::Antibacterial potency of cephalosporins depends on inhibition (acylation) of one or more penicillin-binding proteins (PBP). Recently, reduced affinity of PBP for cephalosporins and other B-lactam agents has been found in some cases. Mechanism for these changes in affinity are analyzed in this review. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Garrido J,López F

    更新日期:1989-09-01 00:00:00

  • [Microbiology in Chile: development through a century of existence].

    abstract::Microbiology starts in Chile at the end of the XIXth century as part of the effort to develop basic sciences at the University of Chile Medical School. Publications by Vicente Izquierdo on gonorrheae and Alejandro del Río on the organisms of dysenteriae were pioneer works in this area. The field was progressively deve...

    journal_title:Revista medica de Chile

    pub_type: 历史文章,杂志文章

    doi:

    authors: Rodríguez M

    更新日期:1992-04-01 00:00:00

  • [Endoscopy after bariatric surgery: what the endoscopist must know].

    abstract::Endoscopy is essential in the assessment and treatment of the bariatric patient, especially in the postoperative state. Since bariatric surgery is increasing exponentially, endoscopists should be familiar with the anatomy and how to manage possible complications. New less invasive therapeutic tools will have a major i...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872020000100083

    authors: Díaz R,Narvaez A,Welsh L,Pérez JE,Dávalos G,Portenier D,Guerron AD

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  • [Etiology and biomarkers of systemic inflammation in mild to moderate COPD exacerbations].

    abstract:BACKGROUND:The etiology of acute exacerbations of chronic obstructive pulmonary disease (COPD) is heterogeneous and still under discussion. Inflammation increases during exacerbation of COPD. The identification of inflammatory changes will increase our knowledge and potentially guide therapy. AIM:To identify which inf...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872012000100002

    authors: Saldías PF,Díaz PO,Dreyse DJ,Gaggero BA,Sandoval AC,Lisboa BC

    更新日期:2012-01-01 00:00:00

  • [Association between physical fitness parameters and health related quality of life in Chilean community-dwelling older adults].

    abstract:BACKGROUND:There is no conclusive evidence about the association between physical fitness (PF) and health related quality of life (HRQOL) in older adults. AIM:To seek for an association between PF and HRQOL in non-disabled community-dwelling Chilean older adults. MATERIAL AND METHODS:One hundred and sixteen subjects ...

    journal_title:Revista medica de Chile

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    authors: Guede Rojas F,Chirosa Ríos LJ,Fuentealba Urra S,Vergara Ríos C,Ulloa Díaz D,Campos Jara C,Barbosa González P,Cuevas Aburto J

    更新日期:2017-01-01 00:00:00

  • [Current life expectancy in Chile].

    abstract::An increased life expectancy is associated to a nation's progress. Life expectancy at birth is 78 years in developed countries, 72 in Latin America, 70 in China, 63 in Eastern Europe and 51 in Africa. Chile is the Latin American country with the higher increment in life expectancy, reaching 75 years at birth, during t...

    journal_title:Revista medica de Chile

    pub_type: 社论

    doi:

    authors: Medina Lois E

    更新日期:1999-06-01 00:00:00

  • [The Revista Médica de Chile, 100 years ago].

    abstract::The september 1888 issue of the Journal contains an article by Luis Asta-Buruaga MD, "Ambulances in New York: a system to be instituted in Santiago. In addition to encouraging this project, the idea of establishing small hospitals in peripheral quarters of the city is discussed. Dr Asta-Buruaga was a graduate from Col...

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    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Costa-Casaretto C

    更新日期:1989-01-01 00:00:00

  • [Non-toxigenic hemolytic Vibrio cholerae non-O1 non-O139 fatal septicemia. Report of one case].

    abstract::We report a 70-year-old woman, who had recently consumed shellfish, that was admitted to the intensive care unit with septic shock and died 19 hours later due to a multi-organic failure. Microbiological, serological and molecular assays confirmed a hemolytic tdh+ Vibrio cholerae non-01, non 0139 as the etiologic agent...

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