[Acquired hemophagocytic syndrome treated with HLH 94-04 chemotherapy protocol: Report of four cases].

Abstract:

:Hemophagocytic syndrome is a severe condition of excessive immune activation that has a high mortality in the absence of treatment. The syndrome is classified as primary if associated with congenital or hereditary problems, or secondary/acquired if associated with infectious, autoimmune or oncology diseases. We report four adult cases of the syndrome, one with viral, two with autoimmune and one with idiopathic causes who were successfully treated with HLH 94-04 chemotherapy protocol. Our experience shows that a high index of suspicion, early diagnosis and an opportune therapy are essential in the treatment of this disease.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Beffermann C N,Pilcante S J,Ocqueteau T M,Sarmiento M M

doi

10.4067/S0034-98872015000900010

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

1172-8

issue

9

eissn

0034-9887

issn

0717-6163

pii

S0034-98872015000900010

journal_volume

143

pub_type

杂志文章,评审
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