Abstract:
:Hemophagocytic syndrome is a severe condition of excessive immune activation that has a high mortality in the absence of treatment. The syndrome is classified as primary if associated with congenital or hereditary problems, or secondary/acquired if associated with infectious, autoimmune or oncology diseases. We report four adult cases of the syndrome, one with viral, two with autoimmune and one with idiopathic causes who were successfully treated with HLH 94-04 chemotherapy protocol. Our experience shows that a high index of suspicion, early diagnosis and an opportune therapy are essential in the treatment of this disease.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Beffermann C N,Pilcante S J,Ocqueteau T M,Sarmiento M Mdoi
10.4067/S0034-98872015000900010subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1172-8issue
9eissn
0034-9887issn
0717-6163pii
S0034-98872015000900010journal_volume
143pub_type
杂志文章,评审abstract::Geographical inequalities arising in the death of children under 1 year are studied. Causes regarded as avoidable at the present moment and leading to death are determined and the 27 Regional Chilean Health Services are ranked from best to worse in levels of mortality using cluster analysis. Results show that: 1) t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1982-04-01 00:00:00
abstract::A 37-year-old female with systemic lupus erythematosus and chronic treatment with steroids developed spontaneous bilateral rupture of tendons of both quadriceps muscles below the patella. Surgical treatment was undertaken with good results. The histologic features and a review of the literature are included. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1990-09-01 00:00:00
abstract::This paper reviews the sentences dictated between 1993 and 2002 by the Supreme Courts of Canada and the Unites States, the House of Lords and Supreme Court of the United Kingdom and the European Human Rights Court, about the validity of the legal prohibition of assistance for suicide. These sentences constituted a jud...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872016000400009
更新日期:2016-04-01 00:00:00
abstract::Mycoplasma infections have extrapulmonary manifestations that may be associated with respiratory symptoms and may have skin, heart, gastrointestinal, rheumatologic, neurologic, hematologic involvement. Cold agglutinin mediated autoimmune hemolytic anemia is the most common hematological manifestation. We report a 27-y...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014001000015
更新日期:2014-10-01 00:00:00
abstract::Celiac disease (CD), with a 1% worldwide prevalence, is an enteropathy caused by an autoimmune reaction to gluten in genetically susceptible individuals, which codify for histocompatibility molecules HLA DQ-2/DQ-8. From the anatomical point of view, CD is characterized by intestinal villous atrophy, crypt hyperplasia,...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872009001200012
更新日期:2009-12-01 00:00:00
abstract::This article analyzes important changes in medical practice, focusing in those most deeply perceived by a group of physiciansfrom the Metropolitan Region of Santiago, included in a joint research conducted by the Departments of Psychiatry and Mental Health (East) of the Medical Faculty at the University of Chile and P...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872004000600015
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Autologous hematopoietic cell transplantation (THA) in patients with multiple myeloma and amyloidosis is the standard of care to promote disease free survival and quality of life. AIM:To report our experience with THA in patients with multiple myeloma. MATERIAL AND METHODS:Retrospective review of the hemat...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014001200001
更新日期:2014-12-01 00:00:00
abstract::The new Chilean regulation about patients' rights and duties is generating a significant change in the information that health care professionals must provide to their patients. This issue will gravitate on medical liability. If this duty is accomplished incorrectly, professionals would fall into an illicit act and be...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000800909
更新日期:2018-08-01 00:00:00
abstract::We analyzed the infectious complications associated with the use of permanent central venous catheters (PVC) in pediatric and adult cancer patients. 62 patients used 74 PVC (54 external, 20 subcutaneous), which were in place for an average of 200 days with a total observation period of 14,876 days, 152 febrile episode...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::Impetigo Herpetiformis is a high-risk gestational skin disease that represents a risk for both the mother and offspring. Its management is based on multisystemic support and maternal steroid therapy. When these measures are insufficient to control the disease, the association of ciclosporine to the treatment has been ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872005000900011
更新日期:2005-09-01 00:00:00
abstract::Kidney graft loss because arterial thrombosis is not common and is related to risk factors such as recurrent vascular hemodialysis access thrombosis, collagen-vascular disease, repeated miscarriage, diabetes mellitus and thrombophilia. Patients having this last disorder have an increased risk of repeated thrombosis in...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872007000100014
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis. AIM:To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma. MATERIAL AND METHODS:Review of pathological r...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000400003
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Primary plasma cell leukemia (pPCL) is uncommon, aggressive and has a different biology than multiple myeloma (MM). AIM:To report the features of patients with pPCL. MATERIAL AND METHODS:Review of databases of the Hematology Department and the Hematology laboratory. RESULTS:Of 178 patients with monoclonal...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019000100018
更新日期:2019-01-01 00:00:00
abstract::An analysis of the interaction of evolutionary factors such as migration, mutation, selection random drift, and consanguinity upon the genome of Easter islanders is attempted. As many primitive populations, the Easter islanders genome has at least 2/3 of genetic loci in an isogenic state. The HLA system is reduced; ot...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:A high proportion of women consulting for depression have a history of childhood abuse and trauma. AIM:To compare the efficacy and costs associated with a treatment that enquires directly into childhood trauma and understands present interpersonal difficulties as a compulsion to repeat the traumatic past, v...
journal_title:Revista medica de Chile
pub_type: 杂志文章,随机对照试验
doi:/S0034-98872010000400006
更新日期:2010-04-01 00:00:00
abstract::A consensus meeting held by the Chilean Endocrinological Society reached to 22 consensus proposals on the use of iodine-131 in hyperthyroidism and thyroid cancer, that are reported in this paper. Some of these propositions are: 1) Hyperthyroidism: A previous 131I uptake test must be performed. A calculated or an ablat...
journal_title:Revista medica de Chile
pub_type: 共识发展会议,杂志文章,评审
doi:
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:The prevalence of pediatric arterial hypertension (AHT) is approximately 1% to 2%. In the last tenyears, mean blood pressure levels (BP) have raised due to obesity and changes in lifestyles. Family history (FH) of AHT is a risk factor to develop AHT in children. AIM:To assess blood pressure, cardiovascular ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000100006
更新日期:2009-01-01 00:00:00
abstract::The functional differentiation of mammary epithelial cells requires specific hormones, growth factors and chemical signals of the cellular environment. These signals consist in cell communication with the extracellular matrix and cell-cell interactions which through an intrincated mechanism lead to the events that tri...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:Cardiac rehabilitation (CR) programs play an important role in the control and prevention of new cardiac events. AIM:A survey was performed to evaluate the current situation of CR programs in Chile. MATERIAL AND METHODS:A questionnaire evaluating the structure of rehabilitation centers, characteristics of ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000500002
更新日期:2012-05-01 00:00:00
abstract::We report a 65 years old female undergoing hemodialysis, presenting with intense pain in the lower right quadrant and moderate hematochezia. Since symptoms did not abate after an appendectomy, a colonoscopy and barium enema were performed, whose results suggested an advanced cecal carcinoma. Biopsies were negative for...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract::The association of hyperthyroxinemia and euthyroidism is frequent and characterized by high plasma thyroxin concentrations, normal TSH values and absence of clinical signs of hyperthyroidism. We report an asymptomatic 28 years old male presenting with a serum total plasma thyroxin of 18.5 micrograms/dl (N 6.1-12.5), a...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract::Starting of from the notion that medicine presents a plurality of aims, it is proposed that it should be conceived as a "science of actions" rather than as a "science of objects". Health is not a neutral "object" that could be unambiguously defined and approached from any vantage point solely with the standards of a d...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND:Patients on chronic hemodialysis have a lower immune response to vaccination against hepatitis B virus (HBV) than the general population. AIM:To identify factors that may interfere with immunization against hepatitis B virus (HBV) in Brazilian hemodialysis patients and analyze the evolution of the level of ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000700008
更新日期:2012-07-01 00:00:00
abstract::Recently, several groups have studied the influence of possible noxious elements present in the intrauterine environment which may favor the development of several diseases in the adult. There is evidence of an increased prevalence of some disorders in special risk groups of fetuses. In the small for gestational age p...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
abstract::A critical situation surrounds Internal Medicine and the training of internists. The crucial role of Internal Medicine as an integrating discipline in clinical medicine and its relationship with primary care medicine and the specialties is analyzed. The goals of a training program for general internists and specialist...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract:BACKGROUND:Adequate management of high blood pressure (HBP) and Type 2 Diabetes (DM2) is a challenge to the healthcare system in Chile. AIM:To evaluate the effectiveness of a case management (CM) approach to manage HBP and DMII at Primary Healthcare (PHC) level, headed by healthcare technicians with the supervision of...
journal_title:Revista medica de Chile
pub_type: 杂志文章,多中心研究
doi:10.4067/S0034-98872018001101269
更新日期:2018-11-01 00:00:00
abstract::This is a comparative review of sick leave and wage replacement policies among countries of the Organization for Economic Co-operation and Development (EOCD), an organism that Chile joined recently. This review also deals with the main transformations applied to the system to improve its effciency and the variables th...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:/S0034-98872011000400013
更新日期:2011-04-01 00:00:00
abstract::Spontaneous hemoperitoneum secondary to intraabdominal variceal rupture, is an uncommon and highly lethal complication of cirrhosis. We report a case of a 68 years old male submitted because of abdominal pain and fainting. The clinical and laboratory work up concluded that the patient had cirrhosis and hemoperitoneum....
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::Both epidemiological and clinical evidence suggest a relationship between the prenatal environment and the risk of developing diseases during adulthood. The first observations about this relationship showed that prenatal growth retardation or stress conditions during fetal life were associated to cardiovascular, metab...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872006000100015
更新日期:2006-01-01 00:00:00
abstract::A national network including 114 blood banks and laboratories performs screening for HIV infection on approximately 250,000 blood donors a year. This represents 100% coverage of blood transfusions performed in Chile. Up to December 1990. 4956 samples had been sent to the National Reference Center for AIDS for suppleme...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00