[Autologous hematopoietic cell transplantation in patients with multiple myeloma. Experience in 53 patients].

Abstract:

BACKGROUND:Autologous hematopoietic cell transplantation (THA) in patients with multiple myeloma and amyloidosis is the standard of care to promote disease free survival and quality of life. AIM:To report our experience with THA in patients with multiple myeloma. MATERIAL AND METHODS:Retrospective review of the hematopoietic cell transplantation database of a hospital of a Medical School. Forty seven patients with multiple myeloma and six with amyloid light chain amyloidosis were identified. Clinical and demographic data were obtained from the records. RESULTS:The overall five year survival of patients was 55%. Transplant-related or non-relapse mortality occurred in 7%. We found no differences in outcomes among patients younger or older than 50 years. CONCLUSIONS:Our data supports that THA can be done in our country with similar results to those obtained in international transplantation centers. Chronological age should not be a limitation to offer this therapy to patients with multiple myeloma and amyloidosis.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Sarmiento M,Lira P,Ocqueteau M,Rodríguez MA,García MJ,Jara V,Bertín P,Ramírez P

doi

10.4067/S0034-98872014001200001

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

1497-501

issue

12

eissn

0034-9887

issn

0717-6163

pii

S0034-98872014001200001

journal_volume

142

pub_type

杂志文章
  • [A national online survey applied to patients with celiac disease in Chile].

    abstract:BACKGROUND:Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. Its prevalence in Europe and the USA is 0.5 to 1%. AIM:To analyze epidemiological aspects and degree of compliance with gluten-free diet (GFD) among Chilean individuals with CD....

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872011000700003

    authors: Espino A,Castillo L C,Guiraldes E,Santibáñez H,Miquel JF

    更新日期:2011-07-01 00:00:00

  • [Non-specific cecal ulcer in a patient with chronic renal failure in hemodialysis treatment. Case report].

    abstract::We report a 65 years old female undergoing hemodialysis, presenting with intense pain in the lower right quadrant and moderate hematochezia. Since symptoms did not abate after an appendectomy, a colonoscopy and barium enema were performed, whose results suggested an advanced cecal carcinoma. Biopsies were negative for...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Bannura G,Melo C,Villamán J,Muñoz M,Levy I

    更新日期:1999-05-01 00:00:00

  • [Causes of blindness and disability pensions in the eastern metropolitan area of Santiago].

    abstract::Between June 1983 and September 1987, 2799 disability pensions were given in the East Santiago Area, population 676,269. Of them, 222 (7.9%) were due to ophthalmological causes. Blindness as defined by the WHO was present in 57 cases. It was caused by myopia (33%), glaucoma (21%), diabetic retinopathy (9.8%), retinal ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Schweikart A,Charlin R,Stoppel J,Jara R,Maul de la Puente E

    更新日期:1991-05-01 00:00:00

  • [Medical, ethical and legal issues in cryopreservation of human embryos].

    abstract::Embryo cryopreservation improves efficiency and security of assisted reproduction techniques. Nonetheless, it can be questionable, so it must be justified from technical, legal and ethical points of view. This article analyses these perspectives. Embryo cryopreservation maximizes the probability of pregnancy, avoids n...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014000700011

    authors: Beca JP,Lecaros A,González P,Sanhueza P,Mandakovic B

    更新日期:2014-07-01 00:00:00

  • [Addisonian crisis caused by metastatic lung cancer. Report of one case].

    abstract::Addisonian crisis as a first manifestation of metastatic disease secondary to cancer is uncommon. We report a 63-year-old man with a history of one year of fatigue, weakness, weight loss and repeated symptomatic hypoglycemia. The cortisol stimulation test with ACTH confirmed primary adrenal insufficiency. While receiv...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872011000900013

    authors: Utreras C,Díaz RE,Ascui R,Caro R,Véliz J,Wohllk N

    更新日期:2011-09-01 00:00:00

  • [The link between obesity and cancer].

    abstract::While some genetic factors may explain the development of cancer, its main causes are related to environmental exposure to carcinogenic agents as well as to the effect of determined lifestyles and habits. Several epidemiological studies have shown a consistent relation between obesity and cancer. In non smokers, obesi...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872014000200010

    authors: Sánchez R C,Ibáñez C,Klaassen J

    更新日期:2014-02-01 00:00:00

  • [The notion of decision making capacity in medical and legal practice].

    abstract:BACKGROUND:The relationship between patients and health professionals emphasizes deliberation and joint decision making, that derives in the informed consent. AIM:To evaluate decision making of patients in health care and to identify the notion of capacity for decision making, according to lawyers and physicians. MAT...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000900009

    authors: Bórquez E G,Raineri B G,Horwitz C N,Huepe O G

    更新日期:2007-09-01 00:00:00

  • [Long term results of mitral balloon valvuloplasty].

    abstract:BACKGROUND:Mitral balloon valvuloplasty (MBV) is the therapy of choice for the treatment of symptomatic mitral stenosis with suitable anatomy. Although its short and mid-term results are favorable, there is a paucity of information about long-term follow-up. AIM:To assess the late results of MBV. MATERIAL AND METHODS...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014001100001

    authors: Martínez R G,Fajuri N A,Córdova A S,Braun J S,Marchant D E,Guarda S E,Veas P N,Méndez L M,Lindefjeld C D,Pérez P O,Flores A,Valenzuela E,Martínez S A

    更新日期:2014-11-01 00:00:00

  • [Age of menarche and genetic blood markers].

    abstract::In 160 girls from low and middle socio-economic class of Santiago we correlated the age at menarque with genetic markers such as ABO blood group, Rh, MN, Xg, haptoglobins, Esterase D and Phosphoglucomutase. No significant association of these markers and age at menarque was found. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Valenzuela C,Avendaño A,Huerta J,Wells P,Gana R

    更新日期:1990-07-01 00:00:00

  • [Cerebral vasodilators].

    abstract::Cerebral vasodilators (CVD) account for 1.6% of the annual expenditure on drugs in Chile. Two kinds are typified: what we have called orthodox CVD and calcium-channel blockers. They have two main uses in neurology: firstly, in acute ischaemic stroke where orthodox CVD (buflomedil, codergocrine mesylate, and nicergolin...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Alvarez G,Vacarezza R

    更新日期:1990-07-01 00:00:00

  • [Concentration of cefotaxime in the exudate from ischemic ulcer after systemic and regional administration].

    abstract::We evaluated the concentration of cefotaxime in the exudate from ischemic leg ulcers in 9 subjects with severe obstructive arterial disease. The administration of the drug was either systemic (1 g in 250 ml of saline given in 30 min) or regional at a vein of the foot while a tourniquet was applied at the level of the ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Acevedo A,Schoop W

    更新日期:1990-03-01 00:00:00

  • [Antimicrobial prophylaxis for transient bacteremia during dental procedures].

    abstract::This review examines the evidence about the relationship between dental procedures and the incidence of transient bacteremia. One of the main obstacles was to define "invasive dental procedure" as an indication for antimicrobial prophylaxis for patients with high risk of bacteremia. A search in WorldWideScience and Sc...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/s0034-98872018000700899

    authors: Fernández E,Reyes C,Benavides C,Irarrázaval T,Padilla P

    更新日期:2018-07-01 00:00:00

  • [Polymorphic reticulosis: a type of lymphoma? Report of 3 cases].

    abstract::Three patients seen at the Medicine Department of Del Salvador Hospital between 1986 and 1990 are reported. All had a history of purulent or bloody nasal discharge and recurrent sinusitis, before the appearance of progressive and painful destructive phenomena that affected the rhino faucial region. The diagnosis was m...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Wainstein E,Vergara I,Segovia A,Guzmán L

    更新日期:1992-11-01 00:00:00

  • [Consensus proposal on the use of 131I in the treatment of thyrotoxicosis and thyroid cancer].

    abstract::A consensus meeting held by the Chilean Endocrinological Society reached to 22 consensus proposals on the use of iodine-131 in hyperthyroidism and thyroid cancer, that are reported in this paper. Some of these propositions are: 1) Hyperthyroidism: A previous 131I uptake test must be performed. A calculated or an ablat...

    journal_title:Revista medica de Chile

    pub_type: 共识发展会议,杂志文章,评审

    doi:

    authors: Michaud P

    更新日期:1998-07-01 00:00:00

  • [Myeloid sarcoma: report of one case with trisomy 11].

    abstract::Myeloid sarcoma is a form of extra-medullary myeloid neoplasia. Cytogenetic characterization is hampered in the absence of invasion to the bone marrow, origin of cells that are usually studied in cytogenetic studies. We report a 13 years old mole presenting with a mass in the right shoulder. A biopsy of the tumor disc...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872011000700013

    authors: Lincopán S A,Valencia M Y,Carrasco L C,Barraza O X

    更新日期:2011-07-01 00:00:00

  • [Cultural and trivial knowledge among Chilean university students].

    abstract:BACKGROUND:Culture is defined by the Webster's dictionary as acquaintance with and taste in fine arts, humanities, and broad aspects of science as distinguished from vocational and technical skills. AIM:To assess the general cultural knowledge of university students. MATERIAL AND METHODS:A test containing 58 question...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872010000300005

    authors: Vargas C NA,Pinochet T D,Juárez E P

    更新日期:2010-03-01 00:00:00

  • [Genetic polymorphism of isoniazid acetylation in Chilean patients with tuberculosis].

    abstract::We studied genetic polymorphism of isoniazid acetylation in 47 tuberculous patients treated with 4 drugs between Aug 1987 and Dec 1988. Inactivation of isoniazid was estimated from urine samples after administration of the drug (10 mg/kg). There were 18 slow and 29 fast acetylators. The frequency of the slow mutant ge...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Ligueros M,Cruz Coke R,Neira S,Saavedra H,Kramer V,Prieto JC,Gelman M,Saavedra A,Nuñez A,Pescio S

    更新日期:1989-12-01 00:00:00

  • [Percutaneous puncture and drainage previous to elective surgical resection of a pheochromocytoma presenting as a retroperitoneal abscess: report of one case].

    abstract::We report a 57 year-old woman with a big partially cystic adrenal pheochromocytoma presenting with high fever and abdominal pain. Based on CT scan images and before knowing urinary catecholamines level, the diagnosis of sepsis secondary to an abscessed adrenal macrotumor was done. A diagnostic percutaneous fine-needle...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872007000400013

    authors: Lam J,Henríquez R,Rojas O,Marina V

    更新日期:2007-04-01 00:00:00

  • [Hyperthyroxinemia and clinical euthyroidism. Report of one case].

    abstract::The association of hyperthyroxinemia and euthyroidism is frequent and characterized by high plasma thyroxin concentrations, normal TSH values and absence of clinical signs of hyperthyroidism. We report an asymptomatic 28 years old male presenting with a serum total plasma thyroxin of 18.5 micrograms/dl (N 6.1-12.5), a...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: López JM,Mosso L,Campino C

    更新日期:1999-02-01 00:00:00

  • Longterm remission of left posterior fascicular ventricular tachycardia due to mechanical trauma.

    abstract::We present a case of a 28 year old woman with paroxysmal left posterior fascicular ventricular tachycardia (LPFVT). Ventricular tachycardia was not inducible after completing of left ventricle 3D reconstruction. Even though catheter ablation was not performed, no LPFVT recurrence has been documented during 60 months f...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872010000800011

    authors: Parizek P,Popelka J,Haman L

    更新日期:2010-08-01 00:00:00

  • [Effects of neomycin on intestinal digestion, absorption and fermentation of carbohydrates in patients with liver cirrhosis: evidence for an alternative therapeutic mechanism in hepatic encephalopathy].

    abstract:BACKGROUND:Despite non absorbable antibiotics and neomycin may have antagonistic effects on intestinal bacterial environment, both have synergistic effects in the treatment of hepatic encephalopathy. This could be due to their action on different enteric flora or a neomycin induced carbohydrate malabsorption. AIM:To i...

    journal_title:Revista medica de Chile

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Chesta J,Antezana C

    更新日期:1994-04-01 00:00:00

  • [Intensive chemotherapy for Burkitt lymphoma in HIV positive patients].

    abstract:BACKGROUND:Burkitt lymphoma has a low incidence, is highly aggressive, may be endemic, sporadic or associated with immunodeficiency and it has a high frequency of extranodal involvement. Overall and relapse free survival in HIV patients is 72 and 71% respectively. However, the current protocol in Chile considers a posi...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872015001200001

    authors: Puga L B,Bustamante K K,Molina E J,Andrade M A

    更新日期:2015-12-01 00:00:00

  • ["Revista Médica de Chile": 120 years (July 1872-July 1992)].

    abstract::The "Revista Medica de Chile" founded in 1872 is the second oldest medical journal in Latin America after the "Gaceta Medica de Mexico" (1864). Among medical journals in the world it is placed 24. It has been published monthly without interruption, except for the period January through December 1891, due to the revolu...

    journal_title:Revista medica de Chile

    pub_type: 历史文章,杂志文章

    doi:

    authors: Costa-Casaretto C

    更新日期:1992-07-01 00:00:00

  • [Predictive value of dipyridamole myocardial perfusion tomography on survival].

    abstract:BACKGROUND:Dipyridamole (DIP) is the most commonly employed pharmacological stressor for myocardial perfusion tomography (SPECT) in patients unable to reach an adequate work load. AIM:To assess the predictive capacity of DIP SPECT on survival. MATERIAL AND METHODS:We included 985 adults aged 66 ±11 years (45% women) ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872018000800831

    authors: Alarcón L,Rau M,Prat H,Fernández R,Carmona J,Zhindon JP,González J,Massardo T

    更新日期:2018-08-01 00:00:00

  • [1st sexual intercourse and 1st pregnancy in puerperal women at a hospital of the metropolitan area].

    abstract::One thousand women hospitalized at a maternity were surveyed after their delivery or abortion about their first sexual intercourse and pregnancy. Mean age at the first sexual intercourse was 18.7 years and only 9.2% used a contraceptive method in spite that 20% were not willing to become pregnant. The mean age of sexu...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Henríquez R,Vargas NA

    更新日期:1995-07-01 00:00:00

  • [Bovine serum albumin (BSA) antibodies in children with recently diagnosed type 1 diabetes with breast feeding and milk exposition].

    abstract:BACKGROUND:Environmental and genetic factors (viruses, toxins and diet) are involved in the aetiology of type 1 diabetes. Among the dietary factors, the role of breast feeding and exposure to cow's milk proteins deserve special attention. AIM:To determine the anti-BSA-IgG levels in type 1 diabetic children and to anal...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Oyarzún A,Santos JL,Carrasco E,Albala C,Salinas A,Pérez F

    更新日期:2003-08-01 00:00:00

  • [Extracorporeal membrane oxygenation in adult respiratory distress syndrome. Experience in 2 patients].

    abstract::We report two female patients with adult respiratory distress syndrome and severe respiratory failure in whom extracorporeal membrane oxygenation was used. Its indication was due to a bad response to conventional treatment with mechanical ventilation and high levels of positive end expiratory pressure. A 2.0 or 2.2 m2...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Alamo M,Castro J,Alvarez E,Brunet L

    更新日期:1995-10-01 00:00:00

  • [Chronic inflammatory demyelinating polyneuropathy. Report of six cases].

    abstract::Chronic inflammatory demyelinating polyneuropathy is a heterogeneous disease characterized by symmetrical motor and sensitive alterations, absence of tendon reflexes and increased cerebrospinal fluid protein levels. We report 6 patients with the disease, (three males) aged 41 to 70 years old. Four had the classical pr...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Araya P,Fruns M,Silva C,Pedraza L

    更新日期:1996-11-01 00:00:00

  • Hepatitis viruses: not always what it seems to be.

    abstract::The classic hepatotropic viruses, hepatitis A through E, are not the only viral agents able to infect the liver. Other systemic viruses may cause hepatic injury that can range from mild and transient elevation of aminotransferases to acute hepatitis and occasionally acute liver failure and fulminant hepatitis. The cli...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:/S0034-98872010001100016

    authors: Gallegos-Orozco JF,Rakela-Brödner J

    更新日期:2010-10-01 00:00:00

  • [Echotomographic findings in gastric cancer].

    abstract::Echotomographic studies were performed in 163 patients with gastric cancer from 1984 to 1990. The technical aspects of the examination and the images obtained in different lesions are described. Emphasis is placed on local or diffuse wall infiltration, ulcerations, vegetations or stenotic lesions. Consideration of the...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Arroyo A,Mánquez P,Traipe E

    更新日期:1992-01-01 00:00:00