Abstract:
BACKGROUND:Oral cancer in Chile corresponds approximately to 1.6% of all cancer cases. There are few studies about oral epithelial dysplasia and oral squamous cell carcinoma in the Chilean population. AIM:To determine the frequency of hyperkeratosis, mild, moderate and severe oral epithelial dysplasia, in situ carcinoma and squamous cell carcinoma of the oral and oropharyngeal mucosa in a registry of the Oral Pathology Reference Institute of the Faculty of Dentistry, Universidad de Chile, in a ten years period. MATERIAL AND METHODS:Review of clinical records and pathological plates of 389 patients, obtained between 1990 and 2009. Cases were selected according to their pathological diagnosis, including hyperkeratosis, oral epithelial dysplasia, in situ carcinoma, squamous cell carcinoma and verrucous carcinoma. RESULTS:Forty four percent of cases were squamous cell carcinoma, followed by hyperkeratosis in 37% and mild epithelial dysplasia in 11%. Squamous cell carcinoma was more common in men aged over 50 years. Most of the potentially malignant disorders presented clinically as leukoplakia and squamous cell carcinoma were clinically recognized as cancer. CONCLUSIONS:In this study, men aged over 50 years are the highest risk group for oral cancer. Early diagnosis is deficient since most of these lesions were diagnosed when squamous cell carcinoma became invasive. Leukoplakia diagnosis is mostly associated with hyperkeratosis and epithelial dysplasia, therefore biopsy of these lesions is mandatory to improve early diagnosis.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Martínez C,Hernández M,Martínez B,Adorno Ddoi
10.4067/S0034-98872016000200004subject
Has Abstractpub_date
2016-02-01 00:00:00pages
169-74issue
2eissn
0034-9887issn
0717-6163pii
S0034-98872016000200004journal_volume
144pub_type
杂志文章abstract::Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, these new therapies, along with greater patient survival, are associated with an increase in untoward effects, particularly in the cardiovascular system. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872018000100068
更新日期:2018-01-01 00:00:00
abstract::We performed real time echotomographic studies in 203 patients with a clinical diagnosis of obstructive jaundice. All patients were operated on and a diagnosis of choledocholithiasis was established in 125. The same diagnosis had been made by echo in 69 of them for a 63% sensitivity rate. The specificity was 92% and t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::ECMO (Extracorporeal Membrane Oxygenation) is an extracorporeal life support system in catastrophic lung failure, shock and cardiopulmonary resuscitation, in different age groups, with multiple physiologic features. When the candidate to be submitted is too unstable to be transported to a hospital with ECMO, cannulati...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872020000300349
更新日期:2020-03-01 00:00:00
abstract::Bacteria have developed sophisticated and successful genetic mechanisms to evade the action of antimicrobials. Bacterial multiresistance has caused serious problems in the treatment of nosocomial infections. Integrons and gene cassettes are considered the main genetic elements in the evolution of plasmids and transpos...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872004000500013
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Crowding in Emergency Departments (ED), results from the imbalance between the simultaneous demand for health care and the ability of the system to respond. The NEDOCS scale (National Emergency Department Crowding Scale) measures the degree of crowding in an ED. AIM:To describe ED Crowding characteristics, ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872017000500001
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Maps have played a critical role in public health since 1855, when John Snow associated a cholera outbreak with contaminated water source in London. After cardiovascular diseases, cancer is the second leading cause of death in Chile. Cancer was responsible for 22.7% of all deaths in 1997-2004 period. AIM:To...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872007001100005
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:p53/p21WAF1/CIP1 and mdm-2 proteins play an important role in cell cycle regulation. The study of the pathogenesis of gastric cancer is important to understand how these tumors progress during their natural history. AIM:To study the relationship between the immunohistochemical expression of p53/p21WAF1/CIP1...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract::In our country, acute cecal volvulus is responsible of 3.3% of mechanical large bowel obstructions. More than half of these cases have a history compatible with intermittent cecal volvulus, an usually overlooked diagnosis. The author reports two cases of intermittent cecal volvulus, treated in the last ten years. Both...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract::A 19 yr-old female patient with the diagnosis of late onset adrenal hyperplasia was treated since age 15 with different glucocorticoid preparations and dosage schedules plus spironolactone. In spite of a very good response in terms of amelioration of their hirsutism she experienced cushingoid manifestations associated...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract::Melkersson-Rosenthal syndrome is characterized by facial or lip edema, peripheral facial palsy and scrotal tongue. We report three patients with the syndrome. A 17 years old male had malar and superior lip enlargement that coincided with a peripheral facial palsy. A 40 years old male with recurrent facial palsy presen...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND:Autologous hematopoietic cell transplantation (THA) in patients with multiple myeloma and amyloidosis is the standard of care to promote disease free survival and quality of life. AIM:To report our experience with THA in patients with multiple myeloma. MATERIAL AND METHODS:Retrospective review of the hemat...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014001200001
更新日期:2014-12-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-08-01 00:00:00
abstract::Hospitalization and death due to heart failure and cardiogenic shock is frequent and currently is increasing among the adult population. Although cardiac transplantation is the most effective treatment in patients with end-stage heart failure, its availability is limited. While waiting for transplantation, some patien...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006000800011
更新日期:2006-08-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Myeloid sarcoma is a form of extra-medullary myeloid neoplasia. Cytogenetic characterization is hampered in the absence of invasion to the bone marrow, origin of cells that are usually studied in cytogenetic studies. We report a 13 years old mole presenting with a mass in the right shoulder. A biopsy of the tumor disc...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011000700013
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Twenty to twenty two percent of work related accidents have a direct or indirect relationship with recent alcohol use. AIM:To detect recent alcohol or drug use in patients who required hospitalization for severe work related accidents. PATIENTS AND METHODS:Blood and urine samples were obtained from patient...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::A 51 year old man with acquired immune deficiency syndrome for 2 years developed a chronic leukemia/T cell lymphoma. Anti HTLV-1 antibodies were confirmed by Western Blot. In the last months he developed hypercalcemia and leukocytosis of 130,000. Necropsy confirmed the diagnosis of Leukemia/T cell lymphoma without cut...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::The rapid development of molecular biology techniques as well as recent progress in the understanding of genetic and molecular basis of human diseases have had enormous impact in the practice of clinical pathology. Since new diagnostic (molecular) tools are now available, the concept of Molecular Pathology is emerging...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2001-07-01 00:00:00
abstract::We evaluated the concentration of cefotaxime in the exudate from ischemic leg ulcers in 9 subjects with severe obstructive arterial disease. The administration of the drug was either systemic (1 g in 250 ml of saline given in 30 min) or regional at a vein of the foot while a tourniquet was applied at the level of the ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::We describe findings in 188 patients with Berger's disease, the most frequent primary glomerulopathy in our renal biopsy material (25%). Diagnosis was made by finding IgA and dense mesangial deposits with immunofluorescence and electronmicroscopy, respectively. Patient's age ranged from 3 to 64 years (mean 27), 72 wer...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract::Arterial involvement in Behçet's disease (BD) is less common than venous lesions. The most commonly affected arteries are: the aorta, lower extremity arteries, mesenteric, femoral, coronary, renal, subclavian and pulmonary arteries. The rupture of pulmonary arteries is the main cause of death of patients with EB and t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000400528
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journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1998-04-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010000500015
更新日期:2010-05-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract::The aim of this work is to analyze the distribution of Duffy blood group and the reproductive history of 148 malformed newborns and their mothers compared to 131 control pairs. The mother-child segregation of the system is analyzed using ITO matrixes. A higher frequency of heterozygote mothers for the system was found...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract::A 68 years old male presented with right hypochondrium abdominal pain and jaundice with no other clinical finding. CAT Scan and Ultrasonography showed right lobe bile duct dilatation. Magnetic Resonance Cholangiopancreatography gave an outstanding vision of a restricted right lobe bile duct dilatation associated to ch...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:The nutritional impact of CONIN nutritional recovery centers must be evaluated, considering the current epidemiological situation in Chile and the new therapeutic focus giving more emphasis to ambulatory treatment. AIM:To analyze the nutritional status of children treated at traditional CONIN centers, the r...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Valsartan is an angiotensin AT1 receptor antagonist. Clinical studies have shown that this is an effective and well tolerated drug. AIM:To compare valsartan with other commonly used antihypertensives in a National multicentric study. MATERIAL AND METHODS:Between 1997 and 1998, a pharmacological surveillanc...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2000-05-01 00:00:00
abstract::Docosahexanoic acid (C22:6, DHA) is a highly unsaturated omega-3 fatty acid that forms part of the central nervous and visual system structures. DHA is synthesized from its precursor, alfa-linolenic acid, that is also a omega-3 fatty acid and can be obtained from vegetable oils. Marine organisms, specially fish, are g...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2001-10-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011001200003
更新日期:2011-12-01 00:00:00