Abstract：
BACKGROUND:Felodipine is a calcium channel inhibitor with high vascular selectivity. AIM:To study the effectiveness of felodipine in the treatment of essential hypertension in subjects older than 64 years old. PATIENTS AND OUTCOME:Fifty subjects were studied. After a washout period of four weeks, subjects received a placebo for two weeks followed by the active drug given in an initial dose of 5 mg/day, adjusted to 10 and 20 mg every 21 days if normal blood pressure levels were not attained. RESULTS:Compared to the placebo period, Felodipine treatment reduced blood pressure from 173 +/- 7.5/102 +/- 3.3 mm Hg to 158 +/- 6.3/91 +/- 4.2 mm Hg. There was no orthostatic reduction of blood pressure, and 87% of subjects attained systolic and diastolic pressure levels below 140 and 90 mm Hg respectively. Adverse reactions (edema, cephalea and flushing) were reported by 38% of subjects and in three, the drug was discontinued. There were no changes in laboratory parameters during the treatment period. Quality of life improved during treatment in the items of concentration, health status perception, mood, physical condition, depression, effects of hypertension on life events and initiative. CONCLUSIONS:Felodipine is effective in the treatment of elders with essential hypertension.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Fasce E,Peña L,Fasce Msubject
Has Abstractpub_date
1996-07-01 00:00:00pages
821-7issue
7eissn
0034-9887issn
0717-6163journal_volume
124pub_type
临床试验,杂志文章abstract：:This paper presents recommendations on the care of HIV infected adults based upon the authors' personal experience with close to 700 patients in a multiprofessional pilot center. This medical care has 5 main objectives: 1) Promotion of good health (through standard recommendation of hygiene, health habits and regular ...
journal_title：Revista medica de Chile
pub_type： 杂志文章,评审
doi：
更新日期：1996-08-01 00:00:00
abstract：:Fifty three patients were studied with dipyridamole thallium myocardial scintigraphy, 4 to 6 days after a first episode of myocardial infarction. Localization of infarction was anterior in 25 and inferior in 28. Infarction was confirmed by myocardial scintigraphy in 87% of cases. A non q wave myocardial infarction was...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:Intestinal tuberculosis is rare compared to other forms of the disease. A review of the last 10 years in a General University hospital identified 21 cases diagnosed at autopsy and 8 during life. Most patients were males, older than 30 years of age, alcoholics and originating in southern Chile. Evidence of concomitant ...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:The aim of this study was to assess the predictive value for mortality of admission and daily APACHE II score, mortality due to multiple organ failure and the Organ Failure Score in patients with acute hepatic failure. We retrospectively studied 15 such patients admitted to an intensive care unit. Thirteen patients di...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：:The content and bioavailability of iron contained in Chilean bread was studied in a random sample from 301 bakeries. A wet digestion procedure followed by a colorimetric method was used. Iron bioavailability was examined in 9 adult women using the extrinsic radioactive tag method. The iron content of bread was 2.4 +/-...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：BACKGROUND:The pathophysiological hallmark of the hepatorenal syndrome (HRS) is renal vasoconstriction. Doppler ultrasonography can be used to assess the vascular resistance in small renal intraparenchymal vessels through analysis of the Doppler waveform by a parameter termed Resistive Index (RI). We postulated that th...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：2002-02-01 00:00:00
abstract：:A narrative review of the evidence regarding the role of inflammation in the pathophysiology of coronary heart disease and depression is presented. As a common pathogenic factor, inflammation could explain the frequent association of both diseases. We discuss the benefit of exercise and diet modifications in both cond...
journal_title：Revista medica de Chile
pub_type： 杂志文章,评审
doi：10.4067/s0034-98872020000200224
更新日期：2020-02-01 00:00:00
abstract：:This essay looks into the meaning of today's professionalism and the apparent inconsistency between its growing status and a context of profound changes and dissatisfaction with medical practice. The cultural climate of our times is reviewed, as the framework for understanding changes in the social organization of med...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：10.4067/s0034-98872006000400017
更新日期：2006-04-01 00:00:00
abstract：:DSM-5 is a significant factor in promoting the "remedicalization" of psychiatry as the focus of psychiatric knowledge, developed by the evidence-based medicine movement, shifted from the clinically-based biopsychosocial model to a research-based medical model. DSM-5 purposes are 1]clinical: diagnosis, prevention, earl...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：10.4067/S0034-98872019000400475
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Psychological and biological symptoms occur in the perimenopausal period. However the real prevalence of these, is not well known in Chile. AIM:To determine the prevalence of biological and psychological symptoms and self care sexual health practices of perimenopausal women of Temuco, Chile. PATIENTS AND M...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:Andrés Bello, a Venezuelan intellectual arrived in Chile in 1829. He had a decisive influence on the development of natural sciences and medical sciences in this country. The first formal teaching program in Medicine appeared in 1833, with few students due to the low social prestige of Medicine at that time. The Facul...
journal_title：Revista medica de Chile
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：:The prevalence of obesity among children and teenagers is increasing by 1.5% per year, probably due to a higher consumption of highly caloric foods and to physical inactivity. Hypercholesterolemia, increased insulin levels and high blood pressure of childhood obesity, precede atherosclerosis, coronary artery disease, ...
journal_title：Revista medica de Chile
pub_type： 杂志文章,评审
doi：
更新日期：2000-01-01 00:00:00
abstract：:The september 1888 issue of the Journal contains an article by Luis Asta-Buruaga MD, "Ambulances in New York: a system to be instituted in Santiago. In addition to encouraging this project, the idea of establishing small hospitals in peripheral quarters of the city is discussed. Dr Asta-Buruaga was a graduate from Col...
journal_title：Revista medica de Chile
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Parents have a control role in the development and treatment of eating disorders among teenagers. AIM:To compare attitudes, beliefs and behaviors between mothers of patients with eating disorders and mothers of teenagers without these disorders. MATERIAL AND METHODS:Twenty one mother-sibling pairs of adole...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：/S0034-98872009000600008
更新日期：2009-06-01 00:00:00
abstract：:We report a 70-year-old woman, who had recently consumed shellfish, that was admitted to the intensive care unit with septic shock and died 19 hours later due to a multi-organic failure. Microbiological, serological and molecular assays confirmed a hemolytic tdh+ Vibrio cholerae non-01, non 0139 as the etiologic agent...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：/S0034-98872009000900008
更新日期：2009-09-01 00:00:00
abstract：:Herpes simplex virus type 1 (HSV-1) is ubiquitous, neurotropic, and the most common pathogenic cause of sporadic acute encephalitis in humans. Herpes simplex encephalitis is associated with a high mortality rate and significant neurological, neuropsychological, and neurobehavioral sequels. HSV-1 infects limbic system ...
journal_title：Revista medica de Chile
pub_type： 杂志文章,评审
doi：/S0034-98872011000600013
更新日期：2011-06-01 00:00:00
abstract：:Two patients with traumatic pancreatic pseudocyst are presented. One patient was treated with percutaneous drainage and the other was operated on to perform a cystoenterostomy. Both patients recovered successfully. Diagnosis and treatment of this condition is discussed. ...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：BACKGROUND:There is a paucity of good quality research about the diagnosis of esophageal varices and the prophylaxis and treatment of variceal bleeding in pediatric patients with portal hypertension There is little consensus and practically no evidence-based approach about the management of these patients. AIM:To desc...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：10.4067/S0034-98872016000700008
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:There are doubts wether generic medications have the same bioavailability and efficacy compared with the original drugs developed by pharmaceutical companies with research capabilities. AIM:To compare the pharmacokinetics and clinical (motor) responses of Sinemet and Grifoparkin (generic carbidopa/levodopa ...
journal_title：Revista medica de Chile
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-06-01 00:00:00
abstract：:In the last decades there has been an important decrease in infant mobidity and mortality, but these achievements are not equally distributed across the whole population. Children are one of the most susceptible groups due to their unique vulnerabilities to environmental factors. Unhealthy environments, indoor polluti...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：/S0034-98872009000100016
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:The permanent surveillance of antimicrobial susceptibility of Shigella sp in the Temuco Regional Hospital, allowed us to define the empirical use of antimicrobials in dysenteric syndrome. AIM:To study antimicrobial susceptibility of Shigella strains collected from 1997 to May 2001 and compare the results wi...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND:Obstructive sleep apnea syndrome (OSA) is an important cause of morbidity and mortality in adults. AIM:To evaluate the diagnostic value of clinical features and oximetric data to screen for obstructive sleep apnea before performing polysomnograpy or respiratory polygraphy. MATERIAL AND METHODS:We studied 3...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：/S0034-98872010000800001
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:Behçet's disease (BD) is a rare multisystemic inflammatory disease that is potentially disabling and may cause death. AIM:To describe the characteristics of BD patients from two Chilean centers. PATIENTS AND METHOD:Retrospective review of the clinical records of patients with BD attended in two rheumatolog...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：/S0034-98872009001000008
更新日期：2009-10-01 00:00:00
abstract：:Noncardiogenic pulmonary edema is a well recognized complication of upper airway obstruction. We report the case of a previously healthy 18-year-old male who presented this complication following laryngospasm after anesthesia. He developed severe pulmonary edema with hypoxemia, high cardiac output and low pulmonary ca...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：BACKGROUND:The number of nonagenarians is rapidly growing in Chile. This age group is mainly female, with higher frailty markers and in higher risk of being placed at nursing homes. AIM:To describe features of nonagenarian women and compare them with a group of women between 60-89 years, both living in nursing homes, ...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：10.4067/s0034-98872004000100005
更新日期：2004-01-01 00:00:00
abstract：AIM:to assess the usefulness of fiberoptic bronchoscopy in the etiologic diagnosis of pulmonary infiltrates in patients with AIDS. PATIENTS AND METHODS:in 25 patients with AIDS and pneumonia, 31 fiberoptic bronchoscopies with bronchoalveolar lavage were performed; in 11 occasions, a transbronchial biopsy was also perf...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:99mTc-sestamibi parathyroid SPECT scintigraphy is a useful tool in the pre-operative study of hyperparathyroidism. False negatives (FN) have been reported in 5.7-14% of the examinations. AIM:To characterize 99mTc-sestamibi FN in cases referred for primary hyperparathyroidism (PHP) to a university hospital. ...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：10.4067/s0034-98872017000801021
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Human and animal trichinosis has been recorded in Chile since the late XIX century and is irregularly distributed along the country. From high rates of infection in the early 1900, the frequency of this parasitosis in man has progressively decreased. AIM:To describe and discuss the epidemiological situation...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：:Priapism is a rare complication of hematological diseases. Among leukemia, it is most frequently seen in patients with chronic myeloid leukemia, due to the high leukocyte counts that these patients achieve. We report a 22 years old male who presented with a priapism lasting more than 24 hours. Thirty six hours after a...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:We studied genetic polymorphism of isoniazid acetylation in 47 tuberculous patients treated with 4 drugs between Aug 1987 and Dec 1988. Inactivation of isoniazid was estimated from urine samples after administration of the drug (10 mg/kg). There were 18 slow and 29 fast acetylators. The frequency of the slow mutant ge...
journal_title：Revista medica de Chile
pub_type： 杂志文章
doi：
更新日期：1989-12-01 00:00:00
