[Soft tissue sarcoma. Combined treatment of drug therapy, radiotherapy and conservative surgery].

Abstract:

:The preliminary results of a prospective and cooperative protocol for the treatment of soft tissue sarcomas of trunk and extremities, stages IB-IIIB are presented. Thirty one patients (17 males, 22 with a tumor larger than 5 cm) aged 16 to 68 years, were treated with one dose of epirubicin 70 mg/m2 i.v. and radiotherapy (3000 rads in 10 fractions) Two or three weeks later an ample surgical complications occurred in 6 patients and were all of infectious origin. The median follow up period has been of 26 months. During this period 5 patients presented late surgical complications (edema in 4 and a pathological fracture in 1), 2 patients had a local tumor recurrence and distant metastases appeared in 7. Actuarial survival was 60% at 48 months. Ninety six percent of surviving patients conserved their extremity. It is concluded that with this treatment modality local recurrence is acceptable, morbidity is low and that the majority of patients do not require amputations or crippling resection.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

San Martín S,Pérez R,Sepúlveda M,Rodríguez M,Durán B,Trujillo C,Arraztoa J

subject

Has Abstract

pub_date

1993-02-01 00:00:00

pages

144-7

issue

2

eissn

0034-9887

issn

0717-6163

journal_volume

121

pub_type

杂志文章
  • [The impact of domestic violence on children's health].

    abstract:BACKGROUND:There is close association between maltreatment during pregnancy and child abuse after birth. AIM:To compare anthropometric growth and use of health services of children whose mothers suffered maltreatment with children coming from families without domestic violence. SUBJECTS AND METHODS:A longitudinal stu...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Arcos E,Uarac M,Molina I

    更新日期:2003-12-01 00:00:00

  • [Hydrostatic reduction of intestinal intussusception in children. Experience in 43 cases].

    abstract:BACKGROUND:Intestinal intussusception, a medical emergency, is more commonly idiopathic and ileocolic and occurs with higher frequency in children aged 6 months to 2 years. Barium enema confirms the diagnosis and allows its hydrostatic reduction, that is the treatment of choice of this condition. AIM:To report our exp...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: García C,Flores P,Zúñiga S,Accorsi E,Monsalva R,Lastra M,Montes P

    更新日期:1997-01-01 00:00:00

  • [University students and sex: what they think, what they know, what they do].

    abstract::Using the social survey technique, a random sample of 464 students from the Universidad Austral answered a structured questionnaire about behavior and attitudes towards sex. Results show that the majority of students have had sexual experiences. Men and women differ significantly in motivations and age at the start of...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Repossi A,Araneda JM,Bustos L,Puente C,Rojas C

    更新日期:1993-02-01 00:00:00

  • [SPECT tomography with F 18-fluorodeoxyglucose in a recent myocardial infarction clinical case].

    abstract::We report a 50-year-old woman with a recent myocardial infarction in whom a myocardial perfusion single photon emission computed tomography (SPECT) with Thallium201 was done simultaneously with a F18-fluorodeoxyglucose (FDG) SPECT to study glucose metabolism. Myocardial infarction was located in the anteroseptal and a...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: González P,Coll C,Massardo T,Sierralta P,Humeres P,Aramburú I,Brugère S,Yovanevich J,Ramírez A,Jofré J,Chamorro H,Kuntsmann S,López H

    更新日期:2000-09-01 00:00:00

  • [Presence of DRD4/7R and DAT1/10R allele in Chilean family members with attention deficit hyperactivity disorder].

    abstract:BACKGROUND:Genes for dopamine receptor DRD4 and dopamine transporter DAT1 have been implicated in attention deficit with hyperactivity disorder (ADHD). However, the findings are not conclusive. More studies in populations with different genetic backgrounds may contribute to solve the discrepancies observed. AIM:To tes...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872004000900004

    authors: Carrasco X,Rothhammer P,Moraga M,Henríquez H,Aboitiz F,Rothhammer F

    更新日期:2004-09-01 00:00:00

  • [An update on the pathogenesis of celiac disease].

    abstract::Celiac disease (CD), with a 1% worldwide prevalence, is an enteropathy caused by an autoimmune reaction to gluten in genetically susceptible individuals, which codify for histocompatibility molecules HLA DQ-2/DQ-8. From the anatomical point of view, CD is characterized by intestinal villous atrophy, crypt hyperplasia,...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:/S0034-98872009001200012

    authors: Herrera MJ,Hermoso MA,Quera R

    更新日期:2009-12-01 00:00:00

  • [Constrictive pericarditis as a serious and rare presentation of systemic lupus erythematosus: Report of one case].

    abstract::Constrictive Pericarditis (CP) is an unusual disease. Its most common causes are idiopathic or secondary to cardiac surgery. Less frequently it is caused by connective tissue diseases. We report a 30 years old woman hospitalized due to progressive dyspnea, chest pain and signs of right sided heart failure. During her ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014000800015

    authors: Lustig N,Florenzano P,Sanhueza LM,Cid X,Ramos G,Thone N,Fullerton DA

    更新日期:2014-08-01 00:00:00

  • [Recurrent Impetigo Herpetiformis: successfully managed with ciclosporine. Report of one case].

    abstract::Impetigo Herpetiformis is a high-risk gestational skin disease that represents a risk for both the mother and offspring. Its management is based on multisystemic support and maternal steroid therapy. When these measures are insufficient to control the disease, the association of ciclosporine to the treatment has been ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872005000900011

    authors: Valdés E,Núñez T,Pedraza D,Muñoz H

    更新日期:2005-09-01 00:00:00

  • [A personal view of endocrinology in Chile].

    abstract::In a short historical review of the outstanding changes occurred in the whole of endocrinology and particularly in Chile over the last 60 years -with the background of an infant mortality drop from 200 per thousand in 1940 to 8 per thousand today and a mean life expectancy increase from 42 to 76 years- the author outl...

    journal_title:Revista medica de Chile

    pub_type: 历史文章,杂志文章

    doi:10.4067/s0034-98872005000600017

    authors: Jadresic A

    更新日期:2005-06-01 00:00:00

  • [Nodular goiter recurrent after surgery. A study of its pathogenesis and incidence].

    abstract::We analyzed 33 patients with recurring nodular goiter (from a population of 2,500 operated patients). Recurrence occurred 0.7 to 12 years after surgery. T4, T3, TSH, perchlorate and TRH tests were performed in 18. Results were similar to those in 13 operated patients without recurrence. Administration of thyroid hormo...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Villaseca R,López Caffarena E

    更新日期:1990-01-01 00:00:00

  • [Fluoride concentration in bottled waters sold in Chile].

    abstract:BACKGROUND:Bottled water consumption has currently increased and their fluoride (F) concentration may not be ideal in terms of caries benefit or risk of fluorosis. While low concentrations would have little anticaries effect, high F concentration would increase the risk of dental fluorosis. AIM:To measure F concentrat...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872014000500011

    authors: Fernández CE,Giacaman RA,Cury JA

    更新日期:2014-05-01 00:00:00

  • [Infective complications of the use of permanent central venous catheters in oncology].

    abstract::We analyzed the infectious complications associated with the use of permanent central venous catheters (PVC) in pediatric and adult cancer patients. 62 patients used 74 PVC (54 external, 20 subcutaneous), which were in place for an average of 200 days with a total observation period of 14,876 days, 152 febrile episode...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Barriga F,Varas M,Capdeville MV,Sapunar F,Lira P,Grebe G

    更新日期:1992-07-01 00:00:00

  • [Undergraduate medical students' expectative of their desired profile as medical doctors].

    abstract:BACKGROUND:During the last few years, multiple new medical schools have emerged in Chile, associated to the constant preoccupation to provide a good quality medical care. This created the need to evaluate medical training programs and to open a discussion about the attributes that a good physician should have. AIM:To ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872006000800001

    authors: García-Huidobro D,Núñez F,Vargas P,Astudillo S,Hitschfeld M,Gennero R,Salvatierra L,Benavente A

    更新日期:2006-08-01 00:00:00

  • [Small intestinal bacterial overgrowth in patients with functional gastrointestinal diseases].

    abstract:BACKGROUND:Recent studies have described a high percentage of small intestinal bacterial overgrowth (SIBO) in patients with irritable bowel syndrome (IBS). However, the prevalence of SIBO has not been well established in other functional disorders. AIM:To evaluate the prevalence of SIBO in patients with different func...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872007001000003

    authors: Madrid AM,Defilippi C C,Defilippi G C,Slimming A J,Quera P R

    更新日期:2007-10-01 00:00:00

  • [Pneumonia caused by Streptococcus pyogenes. Report of one case].

    abstract::We report a 58-year-old female presenting with fever and vomiting. The initial laboratory examination disclosed two blood cultures that were positive for Streptococcus Pyogenes. An abdominal CAT scan showed a right basal pneumonia. The patient was treated with antimicrobials and discharged with oral cefadroxil for 21 ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872010000700009

    authors: Ramírez C,Arab JP,Eymin G

    更新日期:2010-07-01 00:00:00

  • [Cutaneous infection by mycobacterium marinum: case report].

    abstract::A 45 year old male who manipulated tropical fish ponds developed painless nodular plaques in both hands. Biopsy showed mononuclear infiltrate of the dermis with few granulomata. Repeated cultures revealed M. marinum (diagnosis confirmed at the WHO/PAHO Reference Center in Canada). Good initial results were obtained wi...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Guarda R,Gubelin W,Gajardo J,Rohmann I,Valenzuela MT

    更新日期:1992-09-01 00:00:00

  • [Prevalence of sexual dysfunction in climacteric women. Influence of menopause and hormone replace therapy].

    abstract:BACKGROUND:Few trials have studied the prevalence of sexual dysfunction (SD) and related risk factors in postmenopausal women using the DSM-IV criteria. AIM:To evaluate the prevalence of SD in menopausal women and the impact of risk factors. PATIENTS AND METHODS:Five hundred thirty four healthy women, 40 to 64 years ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Blümel JE,Araya H,Riquelme R,Castro G,Sánchez F,Gramegna G

    更新日期:2002-10-01 00:00:00

  • [The notion of decision making capacity in medical and legal practice].

    abstract:BACKGROUND:The relationship between patients and health professionals emphasizes deliberation and joint decision making, that derives in the informed consent. AIM:To evaluate decision making of patients in health care and to identify the notion of capacity for decision making, according to lawyers and physicians. MAT...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000900009

    authors: Bórquez E G,Raineri B G,Horwitz C N,Huepe O G

    更新日期:2007-09-01 00:00:00

  • [Pharmacokinetic comparison of Sinemet and Grifoparkin (levodopa/carbidopa 250/25 mg) in Parkinson s disease: a single dose study].

    abstract:BACKGROUND:There are doubts wether generic medications have the same bioavailability and efficacy compared with the original drugs developed by pharmaceutical companies with research capabilities. AIM:To compare the pharmacokinetics and clinical (motor) responses of Sinemet and Grifoparkin (generic carbidopa/levodopa ...

    journal_title:Revista medica de Chile

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Chaná P,Fierro A,Reyes-Parada M,Sáez-Briones P

    更新日期:2003-06-01 00:00:00

  • [Use of the Edinburgh Postnatal Depression Scale to detect postpartum depression].

    abstract:BACKGROUND:Postpartum depression is a serious, common, treatable condition, with broad repercussions in mother and family life, but frequently under diagnosed. A screening tool, the Edinburgh Postnatal Depression Scale (EPDS) could improve the detection rate of depressive symptoms. AIM:To assess the efficacy of EPDS i...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872008000700005

    authors: Castañón S C,Pinto L J

    更新日期:2008-07-01 00:00:00

  • [The duty to inform in the Chilean legislation].

    abstract::The new Chilean regulation about patients' rights and duties is generating a significant change in the information that health care professionals must provide to their patients. This issue will gravitate on medical liability. If this duty is accomplished incorrectly, professionals would fall into an illicit act and be...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872018000800909

    authors: Pizarro W C

    更新日期:2018-08-01 00:00:00

  • [Prevalence of hepatitis C virus antibodies in a hemodialysis unit].

    abstract::The prevalence of hepatitis C antibody was studied using the EIA 2 Abbott assay in patients and staff of the San Juan de Dios Hospital Hemodialysis Unit. The antibody was detected in 29.8% of patients, no member of the staff had positive antibodies. Patients with a positive antibody had been on hemodialysis for a long...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Rodríguez MI,Estay R,Soto JR,Wolff C,Plubins L,Child R,Armas R

    更新日期:1993-02-01 00:00:00

  • [Percutaneous mitral valvuloplasty as a treatment of choice for mitral stenosis. Immediate results and long-term follow-up].

    abstract::We evaluated 77 patients with symptomatic mitral stenosis for balloon valvuloplasty. Five patients were excluded from the procedure due to the presence of intra-atrial thrombi or mitral valve endocarditis as detected by 2D echocardiography. The mean age of the 72 treated patients was 38 +/- 11 years, 68 were NYHA func...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Olmos A,Gajardo J,Lecannelier E,Seguel I,Lama A,Otero C,Fasce E

    更新日期:1991-01-01 00:00:00

  • [False negative spect parathyroid scintigraphy with sestamibi in patients with primary hyperparathyroidism].

    abstract:BACKGROUND:99mTc-sestamibi parathyroid SPECT scintigraphy is a useful tool in the pre-operative study of hyperparathyroidism. False negatives (FN) have been reported in 5.7-14% of the examinations. AIM:To characterize 99mTc-sestamibi FN in cases referred for primary hyperparathyroidism (PHP) to a university hospital. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872017000801021

    authors: Paillahueque G,Massardo T,Barberán M,Ocares G,Gallegos I,Toro L,Araya AV

    更新日期:2017-08-01 00:00:00

  • [Rising infant mortality in down syndrome in Chile from 1997 to 2013].

    abstract:BACKGROUND:Down syndrome (DS) is associated with higher child mortality especially due to cardiac malformations. AIM:To describe the trend in Chilean infant mortality in DS in the period 1997-2013 as compared to the general population without DS. MATERIAL AND METHODS:Raw data on infant deaths were extracted from the ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872016001100009

    authors: Donoso E,Vera C

    更新日期:2016-11-01 00:00:00

  • [Use of intravenous immunoglobulin for the treatment of toxic epidermal necrolysis and Stevens-Johnson/toxic epidermal necrolysis overlap syndrome. Review of 15 cases].

    abstract:BACKGROUND:Toxic epidemial necrolysis (TEN) is an acute adverse drug reaction, that has an unpredictableprogression and a 30% mortality. The incidence of TEN in the general population is approximately 0.4 to 1.2 cases/million/year. It is characterized pathologically by keratinocyte apoptosis which leads to epidemial de...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872009000300009

    authors: Molgó M,Carreño N,Hoyos-Bachiloglu R,Andresen M,González S

    更新日期:2009-03-01 00:00:00

  • [Masters of internal medicine, in Chile: Manuel García de los Ríos Alvarez MD].

    abstract::Master of Internal Medicine is the highest award granted by the Chilean Society of Internal Medicine (Sociedad Médica de Santiago) to its members. Since this award was instituted, in 1981, the Society has given it periodically to the most distinguished Chilean physicians. All nominees are considered a model as a physi...

    journal_title:Revista medica de Chile

    pub_type: 传,历史文章,杂志文章

    doi:/S0034-98872007001100015

    authors:

    更新日期:2007-11-01 00:00:00

  • [Frequency of K-ras mutation in biliary and pancreatic tumors].

    abstract:BACKGROUND:The ras gene family (H-ras, N-ras and K-ras) are oncogenes that mutate frequently in human cancer, specially in tumors of the biliary tract and pancreas. AIM:To determine the frequency of K-ras gene codon 12 mutation in pancreatic and biliary tumors. MATERIAL AND METHODS:Samples of 35 gallbladder, 15 ampul...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872005001200004

    authors: Roa JC,Anabalón L,Tapia O,Melo A,de Aretxabala X,Roa I

    更新日期:2005-12-01 00:00:00

  • [The contribution of Augusto Orrego Luco to Chilean psychiatry].

    abstract::Augusto Orrego Luco born in 1848 and dead in 1933 in Valparaiso, was one of the greatest clinicians and researchers of chilean medicine during the late nineteenth and early twentieth century. Besides being a psychiatrist he contributed to literature, history, politics and medicine. He received his medical degree in 18...

    journal_title:Revista medica de Chile

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Ruiz Torres A

    更新日期:1996-01-01 00:00:00

  • [The genes of the Pascuense population].

    abstract::An analysis of the interaction of evolutionary factors such as migration, mutation, selection random drift, and consanguinity upon the genome of Easter islanders is attempted. As many primitive populations, the Easter islanders genome has at least 2/3 of genetic loci in an isogenic state. The HLA system is reduced; ot...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:

    authors: Cruz-Coke R

    更新日期:1989-06-01 00:00:00