Rodent nutritional model of steatohepatitis: effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency.

abstract：BACKGROUND:It has been reported that cathepsin E (CTSE) is a non-secretory and intracellular aspartic proteinase found in the superficial epithelial cells of the stomach and that it is also expressed in pancreatic ductal adenocarcinoma. We evaluated the diagnostic value of CTSE in the pancreatic juice in the diagnosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Uno K,Azuma T,Nakajima M,Yasuda K,Hayakumo T,Mukai H,Sakai T,Kawai K

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Hypothyroidism is commonly thought to cause decreased gastric emptying but is mostly associated with autoimmune disease. In the present study the gastric emptying function of thyroid cancer patients with severe hypothyroidism of short duration was evaluated with a radionuclide solid meal gastric emptying stu...

journal_title：Journal of gastroenterology and hepatology

authors： Kao PF,Lin JD,Chiu CT,Hsu HT,See LC,Tzen KY

更新日期：2004-06-01 00:00:00

abstract：:The effect of tauro-beta-muricholate (beta MC-tau) and tauro-alpha-muricholate (alpha MC-tau) on oestradiol-17 beta-glucuronide (E217G)-induced cholestasis was compared with that of tauroursodeoxycholate (UDC-tau) in rats. Like UDC-tau, alpha MC-tau and beta MC-tau infused at the rate of 0.2 mumol/min per 100 g bodywe...

journal_title：Journal of gastroenterology and hepatology

authors： Takikawa H,Sano N,Aiso M,Takamori Y,Yamanaka M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatic arterial infusion (HAI) chemotherapy has a number of limitations, including a low rate of complete response and frequent extrahepatic recurrence, in colorectal cancer patients with non-resectable hepatic metastases. METHODS:Twenty-nine colorectal cancer patients with non-resectable hepatic m...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JC,Kim HC,Lee KH,Yu CS,Kim TW,Chang HM,Ryu MH,Kim JH,Ha HK,Lee MG

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Sodium chloride (NaCl) is a strong promoter of gastric cancer. We hypothesized that inducible nitric oxide synthase (iNOS) induced by NaCl may be involved in its promoting effects. We investigated iNOS expression by hypertonic NaCl solutions and its pathophysiological roles in the gastric mucosa of rats and ...

journal_title：Journal of gastroenterology and hepatology

authors： Tatemichi M,Ogura T,Sakurazawa N,Nagata H,Sugita M,Esumi H

更新日期：2003-09-01 00:00:00

abstract：:Sinusoidal endothelial cell damage is produced by activation of hepatic macrophages after endotoxin administration in rats pretreated with Cornyebacterium parvum or undergoing 70% hepatectomy. Such damage causes fibrin deposition in the hepatic sinusoids leading to massive hepatic necrosis. In the C. parvum model, cyt...

journal_title：Journal of gastroenterology and hepatology

authors： Mochida S,Ohno A,Arai M,Fujiwara K

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND AIM:Cytokines play an important role in the pathogenesis of acute pancreatitis (AP). The aim of the present paper was to study the profile of anti- and proinflammatory cytokines in AP and to determine their predictive value for severity of AP, organ failure and mortality. METHODS:Consecutive patients wi...

journal_title：Journal of gastroenterology and hepatology

authors： Sathyanarayan G,Garg PK,Prasad H,Tandon RK

更新日期：2007-04-01 00:00:00

abstract：:A novel experimental model of submassive liver necrosis with impaired regeneration has been established. A novel lipid A analogue, FS-112, was injected intravenously into male BALB/c mice, followed 2 days later by a 70% partial hepatectomy. Over the next 9 days, mice became severely jaundiced, with a peak total biliru...

journal_title：Journal of gastroenterology and hepatology

authors： Maeda T,Ohnishi H,Hayashi T,Ishiki Y,Moriwaki H,Muto Y

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) can now provide a cytopathological diagnosis of underlying pancreatic malignancy with higher success rates than endoscopic retrograde pancreatography (ERP). To determine the significance of EUS-FNA for the diagnosis of pancreatic mass without...

journal_title：Journal of gastroenterology and hepatology

authors： Wakatsuki T,Irisawa A,Bhutani MS,Hikichi T,Shibukawa G,Takagi T,Yamamoto G,Takahashi Y,Yamada Y,Watanabe K,Obara K,Suzuki T,Sato Y

更新日期：2005-11-01 00:00:00

abstract：:In November 2001, a 29-year-old woman was admitted to the hospital because of dysphagia due to an apallic state caused by cerebral anoxia. Nutritional support was maintained by nasogastric tube feeding for approximately 3 months. For improvement of the body state maintenance and quality of life, a percutaneous endosco...

journal_title：Journal of gastroenterology and hepatology

authors： Chen W,Kawahara H,Takahasi M,Matsushima A,Takase S

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIM:T-cell responses against hepatitis C are believed to be critical in achieving both natural and treatment-induced clearance. However, rapid clearance of antigen with early treatment of primary infection may result in reduced or poorly sustained cellular immunity. This study longitudinally examined Th1...

journal_title：Journal of gastroenterology and hepatology

authors： Flynn JK,Dore GJ,Hellard M,Yeung B,Rawlinson WD,White PA,Kaldor JM,Lloyd AR,Ffrench RA,ATAHC Study Group.

更新日期：2013-11-01 00:00:00

abstract：:Quantitative measurement of hepatitis C virus (HCV) RNA is useful in patients with chronic hepatitis C, especially with interferon treatment. We examined the clinical usefulness of the AMPLICOR monitor assay, a newly developed assay for quantitative measurement, by comparing it with two other assays with different pri...

journal_title：Journal of gastroenterology and hepatology

authors： Ichijo T,Matsumoto A,Kobayashi M,Furihata K,Tanaka E

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND AND AIM:Host genetic factors have been reported as influencing the progress to fulminant hepatitis (FH). Our previous data showed the serum level of tumor necrosis factor (TNF)-alpha influenced by gene polymorphisms to be markedly increased. It was investigated whether polymorphisms in the IL-10 gene, in add...

journal_title：Journal of gastroenterology and hepatology

authors： Takakura M,Tokushige K,Matsushita N,Hashimoto E,Shiratori K

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIM:Symptoms and complications of primary biliary cirrhosis (PBC) have been shown to impair patients' health-related quality of life (HRQOL) in the West. We aimed to measure the HRQOL and to determine the factors associated with worse HRQOL among the Chinese PBC patients in Hong Kong. METHODS:Chinese pa...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Law FM,Wong VW,Hui AY,Chan FK,Sung JJ,Chan HL

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND AIM:Intubation of the terminal ileum (TI) demonstrates a complete colonoscopy, but its clinical value during screening exams is unknown. We aimed to determine whether TI intubation during screening colonoscopy is associated with colonoscopy quality measures or identifies subclinical pathology. METHODS:W...

journal_title：Journal of gastroenterology and hepatology

authors： Leiman DA,Jawitz NG,Lin L,Wood RK,Gellad ZF

更新日期：2020-09-01 00:00:00

abstract：:Immune responses against hepatitis C virus (HCV) play a crucial role in the pathogenesis of chronic hepatitis C. HCV infection often persists and leads to chronic hepatitis and eventually cirrhosis. Accumulated data suggest that HCV proteins suppress host immune responses through the suppression of functions of immune...

journal_title：Journal of gastroenterology and hepatology

authors： Hiroishi K,Ito T,Imawari M

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic resection is highly effective treatment option for rectal neuroendocrine tumors (NETs) as they usually present as small localized tumors. However, there are no well-established surveillance strategies following endoscopic resection. We established our own protocol for the surveillance of r...

journal_title：Journal of gastroenterology and hepatology

authors： Chung HG,Goh MJ,Kim ER,Hong SN,Kim TJ,Chang DK,Kim YH

更新日期：2020-08-31 00:00:00

abstract：:Acid-sensing pathways, which trigger mucosal defense mechanisms in response to luminal acid, involve the rapid afferent-mediated "capsaicin pathway" and the sustained "prostaglandin (PG) pathway." Luminal acid quickly increases protective PG synthesis and release from epithelia, although the mechanism by which luminal...

journal_title：Journal of gastroenterology and hepatology

authors： Akiba Y,Kaunitz JD

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known whether routine prophylaxis against Pneumocystis jirovecii pneumonia (PJP) is needed in patients with inflammatory bowel disease (IBD) on immunosuppression, especially in Asian populations. We, therefore, sought to investigate the incidence and risk factors of PJP in patients with IBD...

journal_title：Journal of gastroenterology and hepatology

authors： Nam K,Park SH,Lee J,Jo S,Kim SO,Noh S,Park JC,Kim JY,Kim J,Ham NS,Oh EH,Song EM,Hwang SW,Yang DH,Ye BD,Byeon JS,Myung SJ,Yang SK

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND AIM:Owing to persistent controversy regarding the use of routine antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy and the availability of several new randomized controlled trials (RCTs), we conducted an up-to-date meta-analysis to provide the best current evidence. The ...

journal_title：Journal of gastroenterology and hepatology

authors： Liang B,Dai M,Zou Z

更新日期：2016-05-01 00:00:00

abstract：:This article highlights the importance of hepatotropic viruses as pathogens in patients undergoing transplantation, their contribution to morbidity and mortality after transplantation and the approach to treatment of these pathogens when they cause disease. Although many advances have been made in the management of vi...

journal_title：Journal of gastroenterology and hepatology

authors： Bzowej NH,Wright TL

更新日期：1999-05-01 00:00:00

abstract：:It was recently reported that mutations in the precore and core promoter region of hepatitis B virus (HBV) are associated with fulminant hepatitis. The aim of this study was to investigate the association of mutations in the precore and core promoter region of HBV with fulminant and severe acute hepatitis. We studied ...

journal_title：Journal of gastroenterology and hepatology

authors： Aritomi T,Yatsuhashi H,Fujino T,Yamasaki K,Inoue O,Koga M,Kato Y,Yano M

更新日期：1998-11-01 00:00:00

abstract：:Coffee is one of the most popular beverages in the world. Several studies consistently show that coffee drinkers with chronic liver disease have a reduced risk of cirrhosis and a lower incidence of hepatocellular carcinoma regardless of primary etiology. With the increasing prevalence of non-alcoholic fatty liver dise...

journal_title：Journal of gastroenterology and hepatology

authors： Chen S,Teoh NC,Chitturi S,Farrell GC

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND AIM:Little information is available about the antiviral efficacy of lamivudine (LAM) and entecavir (ETV) in patients with hepatitis B virus (HBV)-related advanced hepatocellular carcinoma (HCC). Thus, we compared the antiviral efficacy of LAM and ETV in these patients. METHODS:The medical records of 134...

journal_title：Journal of gastroenterology and hepatology

authors： Shin HS,Kim SU,Park JY,Kim DY,Han KH,Chon CY,Baatarkhuu O,Ahn SH

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND AIM:Terlipressin has been shown to be effective in the management of hepatorenal syndrome. However, how terlipressin exerts its effect on the renal artery is unknown. The aim of the present study was to assess the effects of terlipressin on systemic, hepatic and renal hemodynamics in cirrhosis. METHODS:...

journal_title：Journal of gastroenterology and hepatology

authors： Narahara Y,Kanazawa H,Taki Y,Kimura Y,Atsukawa M,Katakura T,Kidokoro H,Harimoto H,Fukuda T,Matsushita Y,Nakatsuka K,Sakamoto C

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND AIM:Preoperative chemoradiotherapy (CRT) followed by esophagectomy is a well-known treatment modality for patients with locally advanced esophageal cancer (EC). This study developed an algorithm to predict pathological complete response (CR) in these patients using post-CRT endoscopic category with biops...

journal_title：Journal of gastroenterology and hepatology

authors： Cho CJ,Kang HJ,Park SJ,Kim GH,Park SH,Eo SH,Kim MJ,Kim YH,Park SR,Kim JH,Ahn JY,Kim DH,Choi KD,Song HJ,Jung HY,Park YS,Lee GH

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND AIM:The incidence of colorectal cancer (CC) is increasing in many Asian countries, but decreasing in western countries. The present study examined the local incidence of CC in the past few decades. METHODS:A population based study, using data from Hong Kong (HK) Cancer Registry, was carried out to exami...

journal_title：Journal of gastroenterology and hepatology

authors： Yee YK,Gu Q,Hung I,Tan VP,Chan P,Hsu A,Pang R,Lam CS,Wong BC

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The liver is the major iron storage organ in the body and, as a result, total body iron stores closely regulate hepatocyte iron uptake, storage and release. Transferrin, transferrin receptor and ferritin facilitate these processes. METHODS:Expression of the three proteins was localized by immunohistochemist...

journal_title：Journal of gastroenterology and hepatology

authors： Basclain KA,Jeffrey GP

更新日期：1999-07-01 00:00:00

abstract：:Both celiac disease and non-cirrhotic portal fibrosis are known to be associated with various autoimmune diseases and have numerous immunological abnormalities. Herein two patients with celiac disease having associated non-cirrhotic portal fibrosis are reported. An autoimmune link between the two conditions is likely ...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma BC,Bhasin DK,Nada R

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND AIM:The number of colonoscopies required to reach satisfactory adenoma detection rate (ADR) is not well established. The aim of this study was to identify the appropriate number of procedures required to attain satisfactory ADR for those well-trained endoscopists who have a cecal intubation rate (CIR) ≥ ...

journal_title：Journal of gastroenterology and hepatology

authors： Dong Z,Sun H,Li B,Zhang Q,Sun K,Wang Z,Qian X,Wang J,Zhan T,Jiang Y,Chen Y,Xu S

更新日期：2020-10-26 00:00:00