Coffee and non-alcoholic fatty liver disease: brewing evidence for hepatoprotection?

abstract：BACKGROUND AND AIM:The rate of fibrosis progression per year can predict the time for the development of cirrhosis in chronic hepatitis C (CHC). We assessed the rate of fibrosis progression and the predictors of disease severity in Indian CHC patients. METHODS:Of the 355 treatment-naïve, histologically-proven CHC pati...

journal_title：Journal of gastroenterology and hepatology

authors： Hissar SS,Kumar M,Tyagi P,Goyal A,Suneetha PV,Agarwal S,Rastogi A,Sakhuja P,Sarin SK

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND AIM:Tobacco smoking is a risk factor for gastrointestinal disorders, causing mucosal damage and impairing immune responses. However, smoking has been found to be protective against ulcerative colitis (UC). Human leukocyte antigen (HLA) is a major susceptibility locus for UC, and HLA-DRB1*15:02 has the st...

journal_title：Journal of gastroenterology and hepatology

authors： Lee HS,Kim K,Jung S,Hong M,Kim BM,Yoo DS,Moon JW,Baek J,Hwang SW,Park SH,Yang SK,Han B,Song K,Ye BD

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIM:This study aimed to estimate the time to precursor progression and to identify significant predicators. METHODS:One hundred thirty-three precursor and 311 normal cases detected in a population-based screening were surveyed for 5.5 years. Precursor progression was defined as worsening of dysplasia or...

journal_title：Journal of gastroenterology and hepatology

authors： Wen D,Zhang L,Wang X,Li Y,Ma C,Liu X,Zhang J,Wen X,Yang Y,Zhang F,Wang S,Shan B

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND AND AIM:Data about the efficacy of de novo combination therapies, or optimization strategy by adding the other drug based on the virological response at week 24 of low genetic barrier antiviral agents is still limited. This study aimed to compare the efficacy at week 104 of lamivudine monotherapy (MONO), lam...

journal_title：Journal of gastroenterology and hepatology

authors： Liang X,Cheng J,Sun Y,Chen X,Li T,Wang H,Jiang J,Chen X,Long H,Tang H,Yu Y,Sheng J,Chen S,Niu J,Ren H,Shi J,Dou X,Wan M,Jiang J,Xie Q,Shi G,Ning Q,Chen C,Tan D,Ma H,Sun J,Jia J,Zhuang H,Hou J

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The liver is the major iron storage organ in the body and, as a result, total body iron stores closely regulate hepatocyte iron uptake, storage and release. Transferrin, transferrin receptor and ferritin facilitate these processes. METHODS:Expression of the three proteins was localized by immunohistochemist...

journal_title：Journal of gastroenterology and hepatology

authors： Basclain KA,Jeffrey GP

更新日期：1999-07-01 00:00:00

abstract：:The identification of activated hepatic stellate cells and related cell types as key fibrogenic effectors during liver injury has led to intense evaluation of transcriptional events underlying their behavior. While initial studies focused on characterizing interactions between transcription factors and regulatory regi...

journal_title：Journal of gastroenterology and hepatology

authors： Friedman SL

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Slow waves play an important role in controlling the frequency and propagation of gastrointestinal contractions. However, mechanisms involved in the modulation of slow wave activity in vivo are still unclear. In this study, the roles of different neurotransmitters in the regulation of gastrointestin...

journal_title：Journal of gastroenterology and hepatology

authors： Liu S,Xu J,Chen JDz

更新日期：2007-07-01 00:00:00

abstract：:The key issues that determine the decision between reusable versus disposable accessories are cost and functionality. In most health-care systems the availability and dissemination of endoscopic services relates directly to the resources (i.e. budget) of that system. Given the limitations of health-care budgets, acces...

journal_title：Journal of gastroenterology and hepatology

authors： Haber G

更新日期：2000-10-01 00:00:00

abstract：:The author visited China in 1981 and 1984 and obtained data comparing the incidence of duodenal ulcer in the rice eating districts of the south with the incidence in the wheat, maize and millet eating areas of the north. The evidence suggested a higher prevalence of duodenal ulcer in the rice eating areas than in the ...

journal_title：Journal of gastroenterology and hepatology

authors： Tovey FI

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND AND AIM:The present study was designed to investigate the expression of and humoral response against NY-ESO-1 in patients with hepatocellular carcinoma and to analyze the relationship between expression of NY-ESO-1 mRNA and clinicopathological features. METHODS:NY-ESO-1 mRNA and protein expression in surgic...

journal_title：Journal of gastroenterology and hepatology

authors： Nakamura S,Nouso K,Noguchi Y,Higashi T,Ono T,Jungbluth A,Chen YT,Old LJ,Nakayama E,Shiratori Y

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND AIM:Dendritic cells (DCs) are observed on the Helicobacter pylori-infected gastric mucosa. DCs generally play an important role in the regulation of inflammation. Although stimulation of gastric epithelial cells with H. pylori vacuolating cytotoxin (VacA) has been reported to induce apoptosis and endopla...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JM,Kim JS,Kim N,Ko SH,Jeon JI,Kim YJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND AIM:White opaque substance (WOS) is a novel endoscopic finding in gastric neoplasms, indicating the intracellular accumulation of lipid droplets (LDs). However, gastric lipid metabolism has not been extensively investigated, even in normal mucosa. We investigated the expression profiles of lipid-metaboli...

journal_title：Journal of gastroenterology and hepatology

authors： Enjoji M,Kohjima M,Ohtsu K,Matsunaga K,Murata Y,Nakamuta M,Imamura K,Tanabe H,Iwashita A,Nagahama T,Yao K

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND AIM:Chronic alcoholic liver disease is associated with hepatic insulin resistance, dysregulated lipid metabolism with increased toxic lipid (ceramide) accumulation, lipid peroxidation, and oxidative and endoplasmic reticulum (ER) stress. Peroxisome-proliferator activated receptor (PPAR) agonists are insu...

journal_title：Journal of gastroenterology and hepatology

authors： Ramirez T,Tong M,Chen WC,Nguyen QG,Wands JR,de la Monte SM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:Non-invasive markers are essential to assess the progression of chronic liver diseases to fibrosis/ cirrhosis and the effectiveness of therapeutic strategies. The aim of this study was to evaluate the ability of non-invasive markers to identify significant fibrosis, severe fibrosis, and cirrhosis in ...

journal_title：Journal of gastroenterology and hepatology

authors： Sheptulina A,Shirokova E,Nekrasova T,Blum H,Ivashkin V

更新日期：2016-12-01 00:00:00

abstract：:Despite a high prevalence of liver disease in Viet Nam, there has been no nationwide approach to the disease and no systematic screening of at-risk individuals. Risk factors include chronic hepatitis B (estimated prevalence of 12%), chronic hepatitis C (at least 2% prevalence), and heavy consumption of alcohol among m...

journal_title：Journal of gastroenterology and hepatology

authors： Gish RG,Bui TD,Nguyen CT,Nguyen DT,Tran HV,Tran DM,Trinh HN,International Group for Liver Health in Viet Nam.

更新日期：2012-02-01 00:00:00

abstract：:Infiltrating leucocytes are activated to generate reactive oxygen species or to produce several molecules in inflamed colonic mucosa. To clarify the phenotypical and functional properties of activating cells in colitic mucosa, 23 patients with ulcerative colitis and 13 controls were studied using a combined method for...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Sawa Y,Hara J,Adachi K,Nakamura S,Matsumoto T,Arakawa T,Kuroki T

更新日期：1997-12-01 00:00:00

abstract：:A case-control study was conducted to evaluate the efficacy of ursodeoxycholic acid (UDCA) in the treatment of Chinese patients with chronic hepatitis C. Patients who failed to have sustained responses to interferon (IFN) therapy, refused to take IFN or were unsuitable for IFN treatment were enrolled into this study. ...

journal_title：Journal of gastroenterology and hepatology

authors： Lu CL,Chan CY,Hwang SJ,Lu RH,Lee SD

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatic arterial infusion (HAI) chemotherapy has a number of limitations, including a low rate of complete response and frequent extrahepatic recurrence, in colorectal cancer patients with non-resectable hepatic metastases. METHODS:Twenty-nine colorectal cancer patients with non-resectable hepatic m...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JC,Kim HC,Lee KH,Yu CS,Kim TW,Chang HM,Ryu MH,Kim JH,Ha HK,Lee MG

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND AIM:Symptoms and complications of primary biliary cirrhosis (PBC) have been shown to impair patients' health-related quality of life (HRQOL) in the West. We aimed to measure the HRQOL and to determine the factors associated with worse HRQOL among the Chinese PBC patients in Hong Kong. METHODS:Chinese pa...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Law FM,Wong VW,Hui AY,Chan FK,Sung JJ,Chan HL

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Primary biliary cirrhosis (PBC) might be complicated by osteoporosis, whose etiology remains unknown but seems to be multifactorial. Prevalence rates of 30% to 60% for distal renal tubular acidosis (DRTA) have been reported in PBC patients, generally as incomplete DRTA. Although it is undisputed tha...

journal_title：Journal of gastroenterology and hepatology

authors： Farias AQ,Gonçalves LL,Cançado EL,Seguro AC,Campos SB,Abrantes-Lemos CP,Carrilho FJ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND AIMS:This study was aimed to find clinical predictors for developing delirium tremens (DT) in alcohol dependence. METHODS:This cohort study was retrospectively carried out among patients who were diagnosed as having alcohol dependence between January 2001 and July 2004. Fifteen parameters were compared ...

journal_title：Journal of gastroenterology and hepatology

authors： Lee JH,Jang MK,Lee JY,Kim SM,Kim KH,Park JY,Lee JH,Kim HY,Yoo JY

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) can now provide a cytopathological diagnosis of underlying pancreatic malignancy with higher success rates than endoscopic retrograde pancreatography (ERP). To determine the significance of EUS-FNA for the diagnosis of pancreatic mass without...

journal_title：Journal of gastroenterology and hepatology

authors： Wakatsuki T,Irisawa A,Bhutani MS,Hikichi T,Shibukawa G,Takagi T,Yamamoto G,Takahashi Y,Yamada Y,Watanabe K,Obara K,Suzuki T,Sato Y

更新日期：2005-11-01 00:00:00

abstract：:Better understanding of hepatitis B virus (HBV) replication and the natural history and immunopathogenesis of chronic hepatitis B, together with the introduction of effective agents with different mechanisms of action, is the basis for better therapeutic strategies against chronic hepatitis B. Substantial experience h...

journal_title：Journal of gastroenterology and hepatology

authors： Liaw YF

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:One-third of patients with exacerbations of ulcerative colitis (UC) require colectomy and 1% die. Although several studies have reported parameters associated with failure of medical treatment, studies using multivariate analysis of various predictors are scanty. METHODS:Demographic, clinical and laboratory...

journal_title：Journal of gastroenterology and hepatology

authors： Kumar S,Ghoshal UC,Aggarwal R,Saraswat VA,Choudhuri G

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND AIM:Melibiose/rhamnose permeability test is used for noninvasive intestinal mucosa barrier testing. However, the possible escape route of the absorbed saccharides through either intact or impaired blood-biliary barriers has not so far been explored. The objective of the present study was therefore two-fo...

journal_title：Journal of gastroenterology and hepatology

authors： Tomsik P,Sispera L,Rezacova M,Niang M,Stoklasova A,Cerman J,Knizek J,Brcakova E,Cermanova J,Micuda S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND AIM:Ecabet sodium is reported to have a bactericidal effect on Helicobacter pylori and inhibit urease activity in vitro. METHODS:Seven male volunteers (mean age, 51.3 years; range, 45-55 years) with H. pylori infection were medicated with 1 g ecabet sodium t.i.d. for 4 weeks. The urea breath test (UBT) ...

journal_title：Journal of gastroenterology and hepatology

authors： Okuda M,Yamamoto N,Fukuda N,Maekawa K,Kusaka T,Hashimoto M,Kotake J,Koizuka H,Fukuda Y

更新日期：2012-04-01 00:00:00

abstract：:Wilson's disease is an autosomal recessive, inborn error of copper metabolism. The basic defect is unknown but decreased biliary excretion of copper is associated with copper accumulation and damage to the liver, brain and other organs with variable clinical expression. The gene for the disease has been mapped to band...

journal_title：Journal of gastroenterology and hepatology

authors： Frydman M

更新日期：1990-07-01 00:00:00

abstract：:Biliary strictures can be categorized according to technical factor as anastomotic or nonanastomotic strictures. Biliary anastomotic stricture is a common complication after living-donor liver transplantation, occasionally causing deaths. The two most commonly used methods for biliary anastomosis are duct-to-duct anas...

journal_title：Journal of gastroenterology and hepatology

authors： Chok KS,Lo CM

更新日期：2014-10-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum ranging from simple steatosis to non-alcoholic steatohepatitis, which causes an increased risk of cirrhosis, type 2 diabetes, and cardiovascular complications. With the worldwide growing incidence of obesity, sedentary lifestyle, and unhealthy dietary pa...

journal_title：Journal of gastroenterology and hepatology

authors： Fan JG,Cao HX

更新日期：2013-12-01 00:00:00