Auditory event-related potentials in schizophrenia and depression.

Abstract:

:Event-related potentials in two auditory target detection paradigms and two auditory paradigms without overt tasks were studied in 22 schizophrenic, 21 depressed, and 28 matched control subjects meeting Research Diagnostic Criteria. In the target detection paradigms, schizophrenics showed a pattern of reduced N120 amplitude and shorter P200 latency to frequently occurring tones, and reduced P300 and Slow Wave amplitude to infrequent target and nontarget tones. This pattern is consistent with impaired selective attention for stimuli. For depressed patients these variables were generally intermediate between those of schizophrenics and controls. In the other paradigms N120 latency was greater for schizophrenics, and P200 amplitude was less for depressed patients.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Roth WT,Pfefferbaum A,Kelly AF,Berger PA,Kopell BS

doi

10.1016/0165-1781(81)90023-8

subject

Has Abstract

pub_date

1981-04-01 00:00:00

pages

199-212

issue

2

eissn

0165-1781

issn

1872-7123

pii

0165-1781(81)90023-8

journal_volume

4

pub_type

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