Abstract:
BACKGROUND:The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk. METHOD:We identified all people (n=568) aged 16-64 years presenting to secondary services with their first psychotic symptoms in three well-defined English areas (over a 2-year period in Southeast London and Nottingham and a 9-month period in Bristol). Standardized incidence rates and incidence rate ratios (IRR) for all major psychosis syndromes for all main ethnic groups were calculated. RESULTS:We found remarkably high IRRs for both schizophrenia and manic psychosis in both African-Caribbeans (schizophrenia 9.1, manic psychosis 8.0) and Black Africans (schizophrenia 5.8, manic psychosis 6.2) in men and women. IRRs in other ethnic minority groups were modestly increased as were rates for depressive psychosis and other psychoses in all minority groups. These raised rates were evident in all age groups in our study. CONCLUSIONS:Ethnic minority groups are at increased risk for all psychotic illnesses but African-Caribbeans and Black Africans appear to be at especially high risk for both schizophrenia and mania. These findings suggest that (a) either additional risk factors are operating in African-Caribbeans and Black Africans or that these factors are particularly prevalent in these groups, and that (b) such factors increase risk for schizophrenia and mania in these groups.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Fearon P,Kirkbride JB,Morgan C,Dazzan P,Morgan K,Lloyd T,Hutchinson G,Tarrant J,Fung WL,Holloway J,Mallett R,Harrison G,Leff J,Jones PB,Murray RM,AESOP Study Group.doi
10.1017/S0033291706008774subject
Has Abstractpub_date
2006-11-01 00:00:00pages
1541-50issue
11eissn
0033-2917issn
1469-8978pii
S0033291706008774journal_volume
36pub_type
杂志文章,多中心研究abstract:INTRODUCTION:Cognitive therapy (CT) for bipolar disorder emphasizes the monitoring and regulation of mood, thoughts and behaviour. The Sense of Hyper-Positive Self Scale (SHPSS) measures the extent to which bipolar patients value themselves and perceive themselves to possess personal attributes (e.g. dynamism, persuasi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704002910
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:The goal of this study is to determine the association between panic attacks in adolescence and the risk of personality disorders during young adulthood. METHOD:Data were drawn from the Children in the Community Study, a longitudinal epidemiological study of psychopathology across the life-course in 717 indi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704003319
更新日期:2005-02-01 00:00:00
abstract::The validity of the twin method depends on the equal environment assumption (EEA)--that monozygotic (MZ) and dizygotic (DZ) twins are equally correlated in their exposure to environmental factors of aetiological importance for the trait under study. Parents may treat MZ twins more similarly than DZ twins thereby poten...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700027732
更新日期:1994-08-01 00:00:00
abstract::Patients diagnosed on the basis of structured interviews as having affective psychoses were less sensitive in detecting the presence of a transient auditory signal than were schizophrenic patients or non-patients. Patients with affective psychoses also benefited more (their reaction time was more reduced) than the oth...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700056622
更新日期:1975-08-01 00:00:00
abstract::A consecutive series of 45 female bulimic patients treated by one of us was followed four to six years after termination of treatment. Thirty-five (78%) were successfully followed, six refused to participate in the study and four were untraced. At least seven (16%) had diagnosable bulimia nervosa at follow-up, and at ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700005766
更新日期:1989-11-01 00:00:00
abstract::Instruments designed to assess psychiatric disorders in people with learning difficulties (mental handicap) were critically reviewed from a psychometric perspective. Major trends were found in the assessment of psychopathology related to DSM-III and depressive disorders although research in other areas was patchy. Alt...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/s0033291700014732
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:Generalized anxiety disorder (GAD) is highly co-morbid with depression. Depression is associated with elevated levels of the inflammation marker C-reactive protein (CRP), cross-sectionally and over time. To date, no studies have looked at the association between CRP and GAD. METHOD:A total of nine waves of ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000554
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Findings from family and twin studies support a genetic contribution to the development of sexual orientation in men. However, previous studies have yielded conflicting evidence for linkage to chromosome Xq28. METHOD:We conducted a genome-wide linkage scan on 409 independent pairs of homosexual brothers (90...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714002451
更新日期:2015-05-01 00:00:00
abstract::A monotonous voice is produced by schizophrenic patients whose expression of emotion is damped down and by patients with a severe degree of depression. Clinically, the distinction between these two diagnostic entities is virtually impossible to establish auditorily on the basis of voice quality alone. The laryngograph...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700041349
更新日期:1981-11-01 00:00:00
abstract:BACKGROUND:Several studies have reported smaller hippocampal volume (HcV) in depression patients; however, the temporality of the association remains unknown. One proposed hypothesis is that depression may cause HcV loss. This study evaluates whether previous depression and recent depressive symptoms are associated wit...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714003055
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:The methodology for measuring the needs of patients with severe mental illness is now well established through the MRC Needs for Care Assessment Schedule and its modification in the form of the Cardinal Needs Assessment. This paper reports the rationale and construction of a relatives' version of the Cardina...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329179800662x
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:A number of studies have suggested that indirect semantic priming is enhanced in thought-disordered schizophrenics. However, research on direct semantic priming has produced conflicting results. The aim of the present study was to resolve some of the ambiguities of previous findings. METHODS:For the present...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003105
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:Resting pulse is robustly and inversely associated with the risk for externalizing disorders and may be positively associated with internalizing disorders. We know little about the causal nature of these associations. METHODS:We examined resting pulse at conscription examination in 369 301 males born 1960-8...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000549
更新日期:2020-03-24 00:00:00
abstract:BACKGROUND:Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed depression is scarce. We examined job strain as a risk factor for ...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1017/S003329171600355X
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Certain personality traits predispose to criminal behavior (CB). We further clarify this relationship in a Swedish national sample. METHOD:Psychological strength (PS) was assessed on a nine-point scale at personal interview in 1 653 721 Swedish men aged 18-20 years. We examined the association between PS an...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715001403
更新日期:2016-01-01 00:00:00
abstract::Neuropsychological tests of frontal lobe functions were undertaken in 46 chronic schizophrenic patients who were also rated for movement disorders. Tardive dyskinesia was found to have significant associations with most of these psychological tests. The possible mechanisms are discussed within the context of known neo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700032748
更新日期:1992-02-01 00:00:00
abstract::Recent studies have suggested that expanded CAG/CTG repeats contribute to the genetic aetiology of schizophrenia and bipolar disorder. However, the nature of this contribution is uncertain and difficult to predict from other known trinucleotide repeat diseases that display much simpler patterns of inheritance. We have...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700035868
更新日期:1996-11-01 00:00:00
abstract::Parental representation was assessed with the Parental Bonding Instrument (PBI) in 12 monozygotic (MZ) and 19 dizygotic (DZ) same-sexed twin pairs discordant for DSM-III-R schizophrenia. The schizophrenic twins reported less care and more overprotection from both parents than the non-schizophrenic co-twins. Multiple r...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700028439
更新日期:1993-05-01 00:00:00
abstract::There is little evidence of a curvilinear relationship between pre-operative emotionality and post-operative adjustment, as predicted by a model which supposes that moderate preoperative anxiety assists adjustment. This paper suggests that the negative affect, or stress, associated with the work of worry should be dis...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700041246
更新日期:1981-11-01 00:00:00
abstract:BACKGROUND:We examined the relationship between childhood sexual abuse (CSA), and interviewees' recollections of pathogenic parenting, testing for possible retrospective biases in the recollections of those who have experienced CSA. METHODS:Information about CSA, parental divorce and interviewees' recollections of par...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002809
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:The attenuated positive symptoms syndrome (APSS) is considered an at-risk indicator for psychosis. However, the characteristics and developmental aspects of the combined or enriched risk criteria of APSS and basic symptom (BS) criteria, including self-experienced cognitive disturbances (COGDIS) remain under-...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715002627
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Individuals with depression are often found to perform worse on cognitive tests and to have an increased risk of dementia. The causes and the direction of these associations are however not well understood. We looked at two specific hypotheses, the aetiological risk factor hypothesis and the reverse causalit...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720003037
更新日期:2020-09-11 00:00:00
abstract::Five hundred and eighty schoolgirls living in a small North Indian industrial town were screened using the EAT-26. Although twenty-nine per cent scored above the threshold for the questionnaire (greater than or equal to 20), closer scrutiny of the pattern of responses revealed misinterpretations of a large number of q...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700005675
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND:Older adults have the lowest prevalence and incidence of major depressive disorder, although it has been hypothesized that this finding is due in part to differences in expression of psychopathology in later life. The aim of this study was to examine variation in depressive symptomatology in the general popu...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S003329171200027X
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Recent anthropological studies have documented the importance of understanding the relation of culture to the experience of mental illness. The use of interviews that elicit explanatory models has facilitated such research, but currently available interviews are lengthy and impractical for epidemiological st...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291798007065
更新日期:1998-09-01 00:00:00
abstract::In an effort to distil major findings about the nature of human ageing, seven propositions are presented as a guiding frame of reference. This propositional framework is then used to specify some conditions for a positive culture of old age and to advance one possible model of good psychological ageing. This model foc...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/s0033291700029846
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:In a recent placebo-controlled, double-blind crossover trial (n = 52), significant beneficial effects on memory (d = 0.30) and negative symptoms (d = 0.29) were found after 12 weeks of memantine augmentation in patients with clozapine-refractory schizophrenia. In this open-label 1-year extension study we rep...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291716002476
更新日期:2017-01-01 00:00:00
abstract::Diagnostic communication between doctors and patients is thought to differ radically between Japan and Western countries. To understand diagnostic disclosure to psychiatric patients, a questionnaire with six case vignettes was sent to practising psychiatrists in Japan (N = 166) and North America (N = 112). While over ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700032803
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:The ability to decode emotional information from facial expressions is crucial for successful social interaction. Borderline personality disorder (BPD) is characterized by serious problems in interpersonal relationships and emotional functioning. Empirical research on facial emotion recognition in BPD has be...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708004273
更新日期:2009-05-01 00:00:00
abstract::The psychiatric status of patients with chronic fatigue syndrome (N = 34) and muscle disease (N = 24) attending a general medical clinic was studied. Among fatigue patients 14 (41.2%) were cases and a further 9 (26.5%) were subcases of psychiatric disorder as defined by CATEGO. A variety of diagnoses was found. Signif...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170002225x
更新日期:1991-08-01 00:00:00