Abstract:
:Instruments designed to assess psychiatric disorders in people with learning difficulties (mental handicap) were critically reviewed from a psychometric perspective. Major trends were found in the assessment of psychopathology related to DSM-III and depressive disorders although research in other areas was patchy. Although some psychometrically sophisticated measures were identified the area was characterized by an absence of important psychometric data for many measures. Future research should attend to developing assessments of schizophrenia, psycho-sexual disorders, adjustment disorders and the validation of screening procedures and instrument formats. Future studies should include more people with severe and profound learning difficulties.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Sturmey P,Reed J,Corbett Jdoi
10.1017/s0033291700014732subject
Has Abstractpub_date
1991-02-01 00:00:00pages
143-55issue
1eissn
0033-2917issn
1469-8978journal_volume
21pub_type
杂志文章,评审abstract:BACKGROUND:Most studies underline the contribution of heritable factors for psychiatric disorders. However, heritability estimates depend on the population under study, diagnostic instruments, and study designs that each has its inherent assumptions, strengths, and biases. We aim to test the homogeneity in heritability...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718002039
更新日期:2019-05-01 00:00:00
abstract::This paper describes a modified version of the MRC Needs for Care Schedule (the Cardinal Needs Schedule), for measuring needs for psychiatric and social care amongst patients with severe psychiatric disorders. The modified schedule has three new features: (i) it is quick and easy to use; (ii) it takes systematic accou...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700033511
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:We sought to clarify the etiological contribution of genetic and environmental factors to total criminal behavior (CB) measured as criminal convictions in men and women, and to violent (VCB), white-collar (WCCB) and property criminal behavior (PCB) in men only. METHOD:In 21 603 twin pairs from the Swedish T...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714002098
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Delusion is the most characteristic symptom of psychosis. While researchers suggested an association between changes of the cortical salience network (CSN) and delusion, whether these CSN findings are a cause or a consequence of delusion remains unknown. METHOD:To assess the effect of CSN functioning to for...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716001057
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Most research on the prevalence, distribution, and psychiatric comorbidity of intellectual disability (ID) relies on clinical samples, limiting the generalizability and utility of ID assessment in a legal context. This study assessed ID prevalence in a population-representative sample of US adolescents and e...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718001605
更新日期:2019-04-01 00:00:00
abstract::Recent literature on insight has paid little attention to patients' social backgrounds and cultures. Discharge summaries from 357 patients with a psychotic illness were examined to investigate factors associated with insight. A highly significant association was found between British white ethnic origin and being thou...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700035406
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Agitated patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians differ in opinion and practice. In Lebanon, the use of the triple therapy haloperidol plus promethazine plus chlorpromazine (HPC) is frequently used but no studies involving t...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004869
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:Impaired spatial working memory (SWM) is a robust feature of schizophrenia and has been linked to the risk of developing psychosis in people with an at-risk mental state (ARMS). We used functional magnetic resonance imaging (fMRI) to examine the neural substrate of SWM in the ARMS and in patients who had jus...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710000280
更新日期:2010-12-01 00:00:00
abstract::The incidence of cavum septum pellucidum (CSP), which has been widely regarded as a developmental anomaly of little clinical importance in neuropathology, was examined in 113 patients with affective disorders (69 with bipolar disorder and 44 with major depression), 40 schizophrenic patients, and 92 control subjects by...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700034838
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Several lines of evidence indicate a role of the brain-derived neurotrophic factor (BDNF) in the modulation of eating behaviour. Therefore, alterations in the physiology of this neurotrophin may be involved in the pathogenesis of eating disorders. In the present study, we investigated serum levels of BDNF in...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704003368
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Decreased white matter (WM) integrity in patients with psychotic disorder has been a consistent finding in diffusion tensor imaging (DTI) studies. However, the contribution of environmental risk factors to these WM alterations is rarely investigated. The current study examines whether individuals with (incre...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291718001320
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:We studied whether heterogeneous profiles of cognitive function are relevant to survival in patients with early Alzheimer's disease. METHODS:CAMCOG subscales of cognitive function were used as predictors of survival, together with gender in 157 consecutively referred patients with early Alzheimer's disease....
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291798007375
更新日期:1999-03-01 00:00:00
abstract::Social anxiety disorder is one of the most common comorbid conditions in eating disorders (EDs). The aim of the current review and meta-analysis is to provide a qualitative summary of what is known about social anxiety (SA) in EDs, as well as to compare levels of SA in those with EDs and healthy controls. Electronic d...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291718000752
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Studies have suggested that patients with schizophrenia are impaired at recognizing emotions. Recently, it has been shown that the neuropeptide oxytocin can have beneficial effects on social behaviors. METHOD:To examine emotion recognition deficits in patients and see whether oxytocin could improve these de...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711001413
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Despite markedly different clinical presentations, few studies have reported differences in neuropsychological functioning between mania and depression. Recent work has suggested that differences may emerge on cognitive tasks requiring affective processing, such as decision-making. The present study sought t...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003804
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:The goal of this study is to determine the association between panic attacks in adolescence and the risk of personality disorders during young adulthood. METHOD:Data were drawn from the Children in the Community Study, a longitudinal epidemiological study of psychopathology across the life-course in 717 indi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704003319
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Capturing service users' perspectives can highlight additional and different concerns to those of clinicians, but there are no up to date, self-report psychometrically sound measures of side effects of antipsychotic medications. Aim To develop a psychometrically sound measure to identify antipsychotic side e...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000903
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Maternal smoking has consistently been associated with multiple adverse childhood outcomes including externalizing disorders. In contrast the association between maternal smoking during pregnancy (MSDP) and internalizing (anxiety and depressive) disorders in offspring has received less investigation. METHOD...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716003627
更新日期:2017-01-19 00:00:00
abstract:BACKGROUND:Almost nothing is known about the potential negative effects of Internet-based psychological treatments for depression. This study aims at investigating deterioration and its moderators within randomized trials on Internet-based guided self-help for adult depression, using an individual patient data meta-ana...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291716001562
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Approximately 25% of people with bulimia nervosa (BN) who undertake therapy are treated in groups. National guidelines do not discriminate between group and individual therapy, yet each has potential advantages and disadvantages and it is unclear how their effects compare. We therefore evaluated how group th...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1017/S0033291713002791
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Cognitive models propose that auditory verbal hallucinations arise through defective self-monitoring and external attribution of inner speech. We used a paradigm that engages verbal self-monitoring to examine how deficits in this process are related to symptoms and diagnosis in patients with psychosis. METH...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291705006628
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the d...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002794
更新日期:2020-12-01 00:00:00
abstract::Clinical psychiatric and medical assessments were carried out on a randomly selected sample of Australian prisoners of war captured by the Japanese in 1942 and a sample of combatants from Pacific theatres of war who were not captured. Prisoners of war had significantly more anxiety and depressive 'neuroses' and more m...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700011843
更新日期:1986-11-01 00:00:00
abstract::It has been proposed that a high level of agreement between informants' reports about events and happenings ('objective' data) is a sound basis for establishing (a) the validity of the measure which is based on the reports, and (b) the nature of objective reality. In this paper it is argued that such agreement may not...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700047486
更新日期:1980-08-01 00:00:00
abstract:BACKGROUND:Despite the demonstrable influence of both genes and the family environment on children's behavioural and emotional development, the mechanisms by which these factors are transmitted from parents to their children are not known. Numerous aspects of the family have long been associated with behavioural and em...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291703008948
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Both past depressive episodes and the personality trait of depressive rumination are strong risk factors for future depression. Depression is associated with abnormal emotional processing, which may be a neurobiological marker for vulnerability to depression. A consistent picture has yet to emerge as to how ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711000043
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Depression is a challenge to diagnose reliably and the current gold standard for trials of DSM-5 has been in agreement between two or more medical specialists. Research studies aiming to objectively predict depression have typically used brain scanning. Less expensive methods from cognitive neuroscience may ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720003608
更新日期:2020-11-09 00:00:00
abstract:BACKGROUND:There is still a relative paucity of information about the long-term course of depression. METHODS:Consecutive patients admitted to a teaching hospital psychiatry unit with symptoms of depression, previously assessed at 6 months and 2, 5 and 15 years after index admission, were reviewed at 25 years (N = 49,...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701004743
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:Although family, twin and adoption studies have suggested that lifetime major depression (MD) is a heritable condition, nearly all these studies have relied for the diagnosis on long-term human memory, which is fallible and potentially biased. Could the estimates of heritability of MD be biased by the well-de...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003695
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:The World Mental Health Survey Initiative (WMHSI) has advanced our understanding of mental disorders by providing data suitable for analysis across many countries. However, these data have not yet been fully explored from a cross-national lifespan perspective. In particular, there is a shortage of research o...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713001116
更新日期:2014-03-01 00:00:00