Abstract:
:The relationship of microcalcification to lobulo-ductal dysplasia and non-invasive carcinoma was studied in 20 women with in situ carcinoma of the breast. All had microcalcification on the mammogram and in half there was also mammographic evidence of disruption of the breast structure. Three-quarters of the women presented with breast symptoms. Multifocal carcinoma was found in seven patients and the histology suggested that not all foci may progess to extensive duct infiltration or invasion. Calcification was found to occur both in carcinoma and in adjacent benign breast lesions and in three cases no evidence of calcification was found in the carcinoma, but was present in adjacent epitheliosis. The origin and distribution of microcalcification appears to be the same in epithelial hyperplasia, non-invasive carcinoma and invasive carcinoma and there may be a relationship between the amount of calcification and the activity of the epithelial cells. Microcalcification is not specific to breast cancer, but is a product of increased cellular activity in the lobulo-ductal complex and may be extruded into the surrounding interstitial tissue. This implies that microcalcification on the mammogram, particularly if sparse, demonstrates a high risk area of breast rather than a certainty of the presence of carcinoma.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Price JL,Gibbs NMdoi
10.1016/s0009-9260(78)80109-3subject
Has Abstractpub_date
1978-07-01 00:00:00pages
447-52issue
4eissn
0009-9260issn
1365-229Xpii
S0009-9260(78)80109-3journal_volume
29pub_type
杂志文章abstract::Biochemical, radiological and histological indicators of dialysis bone disease were studied before, 6 months (58 patients) and 12 months (48 patients) after starting treatment with 1 alpha-OH D3. Radiographic healing of subperiosteal erosions was seen after 6 months in 60% and after 12 months in 77% of affected patien...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(82)80330-9
更新日期:1982-01-01 00:00:00
abstract::There is a pressing clinical need to develop accurate, efficient non-contrast magnetic resonance angiography (NC-MRA) techniques. Our efforts in the field have focused on a novel non-subtractive technique called quiescent-interval slice-selective (QISS) MRA. Compared with other NC-MRA techniques, QISS has the advantag...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.12.003
更新日期:2019-01-01 00:00:00
abstract::Of 50 successive in-patients with normal blood urea levels who received ioxaglate (Hexabrix 320; May & Baker Ltd), 60% showed gall-bladder opacification 12-25 h later. None of these patients had been asked to fast after receiving the ioxaglate. This has not been reported previously with any of the presently available ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80198-7
更新日期:1985-09-01 00:00:00
abstract:AIM:To demonstrate the value of pelvic magnetic resonance imaging (MRI) in mapping tumour extension after chemoradiotherapy and before anterior pelvic exenteration in patients with primary carcinoma of the urethra. MATERIALS AND METHODS:The Institutional Review Board approved and issued a waiver of informed consent fo...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2011.07.039
更新日期:2011-11-01 00:00:00
abstract::This study was undertaken to determine whether three commonly used combinations of CT display window settings permit accurate measurement of pulmonary nodule size during thoracic CT examination. Forty-five rounded nodules of synthetic material of approximate soft tissue density (+70 Hounsfield units; HU), varying in s...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81130-4
更新日期:1993-04-01 00:00:00
abstract::Pulmonary cysts, cavities, and honeycombing are seen in a number of systemic disorders. The purpose of this review is to discuss the findings on thin-section computed tomography (CT) in both congenital and acquired multisystem conditions that give rise to multiple cystic spaces in the lungs. Conditions discussed inclu...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2008.09.015
更新日期:2009-04-01 00:00:00
abstract::The incidence of malignant melanoma in the UK is still rising despite public health warnings about the risks of excessive sun exposure. This aggressive tumour can metastasize to virtually any organ, even years after resection of the primary lesion and cause a variety of radiological appearances. This review provides e...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2003.09.020
更新日期:2004-04-01 00:00:00
abstract:AIM:To describe the radiological appearances of immune reconstitution inflammatory syndrome (IRIS) in human immunodeficiency virus (HIV)-infected patients with mycobacterial infections starting highly active anti-retroviral therapy (HAART). MATERIALS AND METHODS:Five consecutive HIV infected patients with IRIS due to ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2003.12.002
更新日期:2004-06-01 00:00:00
abstract:AIM:To gather and compare related clinical studies, and to investigate the accuracy and reliability of deep learning in detecting orthopaedic fractures. MATERIALS AND METHODS:This study is a retrospective combination and interpretation of prospectively acquired data. Articles from PubMed, EMBASE, the Cochrane library ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2020.05.021
更新日期:2020-09-01 00:00:00
abstract::Widespread use of MRI now allows the routine identification of previously unevaluated traumatic bone marrow oedema and haemorrhage. Similar marrow oedema is identified in patients with tumours, hyperaemia and medullary congestion. Patterns and extent of traumatic bone marrow oedema and haemorrhage are dictated by mech...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1053/crad.2000.0585
更新日期:2001-01-01 00:00:00
abstract::The most commonly used modalities in the diagnosis of chronic pancreatitis are ultrasonography, computed tomography (CT) and endoscopic retrograde pancreatography (ERP). Computed tomography scanning is only of value in severe chronic pancreatitis. Both ultrasound and pancreatography are capable of showing ductal chang...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80339-8
更新日期:1988-01-01 00:00:00
abstract::Colour Doppler scans were carried out on 80 patients with breast carcinoma. Both the tumour and the lower axilla were scanned in all 80 patients. Seventy-five patients subsequently underwent axillary lymph node dissection and histological examination. The sensitivity of colour Doppler scanning for axillary node involv...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81774-x
更新日期:1994-03-01 00:00:00
abstract::Healthcare expenditure is continually increasing and projected to accelerate in the future, with an increasing proportion being spent on interventional radiology. The role of cost effectiveness studies in ensuring the best allocation of resources is discussed, and the role of National Institute of Health and Care Exce...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2020.09.017
更新日期:2020-10-17 00:00:00
abstract::Eighty infants have been treated for neonatal necrotising enterocolitis within a period of five years. Twenty-five per cent developed strictures of the small or large intestine. Four cases of atresia including two with multiple cyst formation were seen. Four patients developed severe malabsorption requiring hyperalime...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(79)80036-7
更新日期:1979-01-01 00:00:00
abstract:AIM:To establish a "one-stop" dysphagia service in which a consultation, barium swallow and endoscopy can all be performed in the same hospital visit. MATERIALS AND METHODS:In order to allow both barium swallow examination and endoscopy to be performed on the same day, a novel technique for clearing barium from the up...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2000.0637
更新日期:2001-01-01 00:00:00
abstract:AIM:To evaluate the image quality of contrast-enhanced chest computed tomography (CT) with low tube voltage settings using an iterative reconstruction algorithm (iDose4) and standard dose filtered back projection (FBP) CT in patients with normal body mass index (BMI). MATERIALS AND METHODS:Eighty patients with normal ...
journal_title:Clinical radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.crad.2012.12.009
更新日期:2013-05-01 00:00:00
abstract:AIM:To evaluate the usefulness of pseudo-continuous arterial spin labelling (pCASL) imaging in grading and differentiating histological subtypes of meningiomas. MATERIALS AND METHODS:In this prospective study, conventional magnetic resonance imaging (MRI) with contrast-enhanced T1-weighted images and pCASL were acquir...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.08.005
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To access concordance between radiological severity of aphthae and the more advanced features of Crohn's disease. PATIENTS AND METHODS:In 75 patients with an established diagnosis of Crohn's disease, we evaluated the radiological severity of colonic aphthae by meticulous double-contrast radiography. The degr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(96)80243-1
更新日期:1996-10-01 00:00:00
abstract:AIM:Recent protein expression profiling of breast cancer has identified specific subtypes with clinical, biological, and therapeutic implications. The aim of this study was to identify the mammographic correlates of these novel molecular classes of invasive breast cancer. MATERIALS AND METHODS:The mammographic finding...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2008.06.006
更新日期:2008-11-01 00:00:00
abstract::Sporadic cases or radiation hepatitis have been reported following doses above 3500 rad delivered in 3-4 weeks to the liver. The authors report their experience of radiation hepatitis in two out of 117 consecutive lymphoma cases treated with total abdominal irradiation. These two patients developed clinically overt ma...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(76)80107-9
更新日期:1976-10-01 00:00:00
abstract::Diffuse lung disease is often a difficult clinical and radiographic problem to resolve. Standard computed tomography (CT) techniques are often unhelpful. By combining practical physiological criteria with narrow section CT a protocol has been developed which yields more accurate information and is now the standard met...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80265-3
更新日期:1986-07-01 00:00:00
abstract:AIM:To evaluate the usage, safety, and efficacy of high-dose intravenous metoprolol for heart rate reduction in computer tomographic (CT) coronary angiography. MATERIALS AND METHODS:As this was retrospective analysis of anonymous data, medical ethics committee approval was waived by the regional health research author...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2014.03.003
更新日期:2014-07-01 00:00:00
abstract::In order to estimate the rate of local complications of phlebography we studied a one-year series of 477 patients. Half of the patients were examined with a comparatively highly concentrated contrast medium and half with a more diluted one. Eight patients had local complications, verified by biopsy and/or thermography...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(78)80207-4
更新日期:1978-11-01 00:00:00
abstract:AIM:To evaluate the short-term results of percutaneous stent placement in treating stenosis in the aorta caused by non-specific aortitis (Takayasu's disease). METHOD:Five patients were treated by this method, all of whom had uncontrolled hypertension, haemodynamically significant stenosis in the aorta and a clinically...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(99)91239-4
更新日期:1999-01-01 00:00:00
abstract:AIM:To examine whether Positron Emission Tomography Response Criteria in Solid Tumours (PERCIST) is useful to predict tumour response and prognosis of patients with oesophageal cancer who received neoadjuvant chemoradiotherapy (NACRT) followed by surgery. MATERIALS AND METHODS:This multicentre retrospective study incl...
journal_title:Clinical radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.crad.2019.09.132
更新日期:2020-01-01 00:00:00
abstract:AIM:To determine the diagnostic performance of unenhanced magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI; NonMRI) for the detection of primary small (≤20 mm) pancreatic solid tumours and prediction of pancreatic ductal adenocarcinoma (PDAC) in comparison with pancreatic computed tomography (CT; P...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.07.009
更新日期:2017-12-01 00:00:00
abstract::Cytomegalovirus (CMV) is the most commonly transmitted virus in utero with a prevalence of up to 1.5%. The infection has potentially debilitating and devastating consequences for the infected fetus, being a leading cause for neurological disability worldwide. Once acquired, it often goes undetected with only an assume...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2020.02.009
更新日期:2020-08-01 00:00:00
abstract::The ability to deliver cells in appropriate doses to their targeted site of action is a well-known obstacle to optimising stem cell therapy. Systemic administration of cells results in pulmonary "trapping," which significantly decreases the number of available circulating cells to impact underlying disorders. Directed...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2016.01.005
更新日期:2016-04-01 00:00:00
abstract::Myeloproliferative neoplasms (MPNs) are a heterogeneous group of haematological disorders including polycythaemia vera (PV), essential thrombocythaemia (ET), primary myelofibrosis (PMF), and chronic myeloid leukaemia (CML). These disorders show large overlap in genetic and clinical presentations, and can have many dif...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.05.014
更新日期:2017-10-01 00:00:00
abstract::Ultrasound examination was conducted in 151 proven cases of amoebic liver abscess. In the majority of patients the lesion was solitary but 25% of patients had multiple lesions; 17% of all the abscesses were in the left lobe of the liver. Most abscesses had no, or very few internal echoes and these were either of the s...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(79)80020-3
更新日期:1979-11-01 00:00:00