Abstract:
:The ability to deliver cells in appropriate doses to their targeted site of action is a well-known obstacle to optimising stem cell therapy. Systemic administration of cells results in pulmonary "trapping," which significantly decreases the number of available circulating cells to impact underlying disorders. Directed delivery of stem cells in interventional radiology may provide an additional option for bypassing the lungs, as well as introduce novel potential avenues for decreasing doses required to effect cellular therapy, efficiently obtain local paracrine effects, and/or to simplify targeting strategies.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Prologo JD,Hawkins M,Gilliland C,Chinnadurai R,Harkey P,Chadid T,Lee Z,Brewster Ldoi
10.1016/j.crad.2016.01.005subject
Has Abstractpub_date
2016-04-01 00:00:00pages
307-11issue
4eissn
0009-9260issn
1365-229Xpii
S0009-9260(16)00010-6journal_volume
71pub_type
杂志文章,评审abstract:AIM:To assess multiparametric magnetic resonance imaging (mp-MRI) in predicting prostate biopsy results. MATERIALS AND METHODS:Patients who underwent mp-MRI prior to prostate biopsy were prospectively included. The prostate was subdivided into 14 sectors and mp-MRI findings assessed using a five-level subjective suspi...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2013.10.018
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:To determine the effect of breathing on the detection of small dense pulmonary nodules of threshold conspicuity by spiral computed tomography (SCT). MATERIALS AND METHODS:Forty pulmonary nodules of high density were created by endobronchial deployment of 2 and 4mm diameter beads in the peripheral airways of ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(98)80170-0
更新日期:1998-07-01 00:00:00
abstract::Cavernous haemangiomas (CH) are relatively uncommon non-shunting vascular malformations of the central nervous system and can present with seizures or with neurological deficits due to haemorrhage. Radiologists can often suggest the diagnosis of CH based on characteristic magnetic resonance imaging (MRI) features, thu...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2011.10.013
更新日期:2012-04-01 00:00:00
abstract::In vivo molecular imaging has a great potential to impact medicine by detecting diseases in early stages (screening), identifying extent of disease, selecting disease- and patient-specific treatment (personalized medicine), applying a directed or targeted therapy, and measuring molecular-specific effects of treatment....
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2010.03.011
更新日期:2010-07-01 00:00:00
abstract:AIM:To investigate whether it is possible to reduce the radiation dose during video fluoroscopic feeding studies below the current 30 frames/s (continuous fluoroscopy). METHODS:Ten consecutive children who had supraglottic penetration while swallowing barium were evaluated as part of a video fluoroscopic feeding study...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2008.07.011
更新日期:2009-01-01 00:00:00
abstract::The different methods of classifying paranasal sinus tumours are summarised. Thirty patients with such tumours seen during the last 2 years were noted. All had had plain films and computed tomography (CT) and 16 conventional tomography. The tumours were staged using Lederman's classification after each investigation t...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(82)80054-8
更新日期:1982-03-01 00:00:00
abstract:AIM:Oral contrast media are commonly given prior to computed tomography (CT) examination of the upper abdomen. Although positive oral contrast media are normally used, there is increasing interest in using negative agents such as water and less commonly fat density products. The aim of this study was to compare a posit...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1053/crad.2001.0772
更新日期:2001-08-01 00:00:00
abstract::Fifteen patients with ruptured hepatocellular carcinomas and intraperitoneal bleeding were considered for hepatic arterial embolization. Embolization was attempted in nine patients (60%) with patent or partially patent portal veins. Successful occlusion of the feeding tumour vessels was achieved in eight patients (53%...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80129-1
更新日期:1993-09-01 00:00:00
abstract:AIM:To explore the value of CT spectral imaging in the differential diagnosis of necrotic hepatocellular carcinoma (nHCC) and hepatic abscess (HA) during the arterial phase (AP) and portal venous phase (PP). MATERIALS AND METHODS:Sixty patients with 36 nHCCs and 24 HAs underwent spectral CT during AP and PP. Iodine or...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2014.08.018
更新日期:2014-12-01 00:00:00
abstract::Thirty-six patients in whom peripheral cavernous haemangioma was clinically suspected were examined by 99mTc red blood cell scintigraphy. Twenty-five of these patients had a palpable lump, and they also underwent an ultrasound examination. Seven patients also had computed tomography and angiography was performed in on...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80224-7
更新日期:1991-07-01 00:00:00
abstract::Extracranial carotid artery aneurysms secondary to accidental injury are rare. We have seen eight lesions of this type in the last 10 years. The aneurysm was produced by blunt trauma in four patients, penetrating shrapnel injury in two, stabbing and electrical injury in one each. The left side was involved in seven pa...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80471-4
更新日期:1991-03-01 00:00:00
abstract:AIM:To determine the value of contrast-enhanced computed tomography (CT)-derived radiomic features in the preoperative prediction of Ki-67 expression in adrenocortical carcinoma (ACC) and to detect significant associations between radiomic features and Ki-67 expression in ACC. MATERIALS AND METHODS:For this retrospect...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2020.01.012
更新日期:2020-06-01 00:00:00
abstract::Radiation therapy of the length of the spinal column presents various clinical and physical problems. The completed plan may be complicated to set up, be time-consuming and require daily variation to achieve reasonable dose homogeneity. A case of medulloblastoma is used to illustrate the steps in producing a plan for ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80126-4
更新日期:1985-03-01 00:00:00
abstract::Pneumatocele of the infratemporal fossa caused by herniation of air through a break in the wall of the aerated maxillary sinus is rare. Two cases are reported: one arising from a maxillary pneumocele with a defect in the wall of the zygomatic recess and one associated with maxillary radionecrosis with pathological fra...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81463-1
更新日期:1992-01-01 00:00:00
abstract:AIMS:To report the magnetic resonance imaging (MRI) findings of osteomalacic insufficiency fractures of the pelvis. MATERIALS AND METHODS:In all, 12 persons presenting with chronic pelvic pain and with a definitive diagnosis of osteomalacia (OM) were enrolled in this study. Radiological work-up included direct radiogr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2004.04.021
更新日期:2005-01-01 00:00:00
abstract::Neuronal migration anomalies form a spectrum of congenital brain malformations with a variety of clinical manifestations. The widespread use of MRI in the investigation of neurological symptoms, and particularly in the imaging of epilepsy, has made the correct recognition and interpretation of these disorders importan...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(96)80211-x
更新日期:1996-01-01 00:00:00
abstract::A case of a middle-aged man with symptomatic, localised chondrocalcinosis of the knee following irradiation is described. Cartilage damage induced by radiotherapy should be added to the list of local factors which can predispose to chondrocalcinosis. ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80302-7
更新日期:1988-07-01 00:00:00
abstract:AIM:To gather and compare related clinical studies, and to investigate the accuracy and reliability of deep learning in detecting orthopaedic fractures. MATERIALS AND METHODS:This study is a retrospective combination and interpretation of prospectively acquired data. Articles from PubMed, EMBASE, the Cochrane library ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2020.05.021
更新日期:2020-09-01 00:00:00
abstract::The purpose of this article is to review the computed tomography (CT) and histopathological features of uncommon primary neoplasms of the thorax that can manifest clinically malignant features (multiplicity of pulmonary nodules, an invasive nature, and metastases or recurrence after surgery) with little evidence of hi...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2012.03.011
更新日期:2012-11-01 00:00:00
abstract::Fifty-eight patients presenting with axillary symptoms (pain, oedema, etc) following radiation therapy for breast carcinoma were randomized to be investigated by either computed tomography (CT: 29 patients) or magnetic resonance imaging (MRI: 28). The objectives of the study were to compare the efficacy of the two tes...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(05)81103-1
更新日期:1993-12-01 00:00:00
abstract::Patients with leukaemia, on anticoagulant therapy, or with disseminated intravascular coagulation may develop occult pulmonary haemorrhage; it will mimic pulmonary oedema, pulmonary hemosiderosis or opportunistic infections. It can be diagnosed by bronchopulmonary lavage. The radiographic changes are described and the...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(78)80217-7
更新日期:1978-03-01 00:00:00
abstract::The results of 100 attempts at endoscopic retrograde cholangio-pancreatography (ERCP) performed in patients with jaundice have been reviewed. The examination provided a diagnosis in 75% of cases. The reason for failure to cannulate the correct duct was obstruction at the lower end of the common bile duct in 15 patient...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(78)80236-0
更新日期:1978-03-01 00:00:00
abstract:AIM:The purpose of this study was to determine the feasibility of echocardiogram (ECG)-gated multi-slice CT angiography (MCTA) in patients with clinical suspicion of acute venous thromboembolism (VTE), to investigate the effect of ECG-gating on cardiac motion artefacts, and to determine the diagnostic reader agreement ...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(03)00348-9
更新日期:2003-11-01 00:00:00
abstract:AIM:To determine the diagnostic performance of colour mapping and strain ratio for characterizing malignant thyroid nodules on ultrasonographic (US) elastography. MATERIALS AND METHODS:The study was approved by the institutional review board and written informed consent was obtained. One hundred and thirty-one patient...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.crad.2013.06.023
更新日期:2013-12-01 00:00:00
abstract::Variations of normal development and benign incidental anomalies are frequently observed on diagnostic neuroimaging. It is important these are recognised for what they are, as misinterpretation may result in unnecessary further investigation, follow-up imaging and anxiety. In this article, we review benign intracrania...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.06.118
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To report the computed tomography (CT) features of afferent loop syndrome which is often clinically unsuspected. MATERIALS AND METHODS:The CT studies of five patients with afferent loop syndrome were reviewed. These patients had undergone gastroenterostomy and other surgical procedures, for malignant neoplas...
journal_title:Clinical radiology
pub_type: 杂志文章,多中心研究
doi:
更新日期:2002-09-01 00:00:00
abstract::Antenatal diagnosis of lung abnormalities by ultrasound has been a much more frequent occurrence in recent years. There is a range of appearances from uniform increased echogenicity through to lesions containing large echo-free areas. Bilateral uniformly increased echogenicity has a poor outlook but in all other situa...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(98)80188-8
更新日期:1998-11-01 00:00:00
abstract:AIM:To investigate the frequency, distribution, and nature of incidental extra-mammary findings detected with breast MRI. MATERIALS AND METHODS:Incidental findings were defined as unexpected lesions outside the breast, not previously known or suspected at the time of referral. Five hundred consecutive breast MRI studi...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.01.003
更新日期:2015-05-01 00:00:00
abstract::We reviewed the initial imaging studies of 283 children with urinary tract infection in order to decide on the most effective approach. A voiding cystogram was performed in all, complemented by either urography (147 patients), ultrasonography (65), or both (71 patients). In the latter group there was good correlation ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(89)80031-5
更新日期:1989-01-01 00:00:00
abstract::The Essure device is a permanent birth-control device, which is gaining popularity. The micro-inserts are composed of metallic elements that can be seen on radiography, computed tomography, ultrasound, and magnetic resonance imaging. Knowledge of the normal location and appearance of the Essure device will ensure appr...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2012.08.013
更新日期:2012-12-01 00:00:00