Interventional stem cell therapy.

Abstract:

:The ability to deliver cells in appropriate doses to their targeted site of action is a well-known obstacle to optimising stem cell therapy. Systemic administration of cells results in pulmonary "trapping," which significantly decreases the number of available circulating cells to impact underlying disorders. Directed delivery of stem cells in interventional radiology may provide an additional option for bypassing the lungs, as well as introduce novel potential avenues for decreasing doses required to effect cellular therapy, efficiently obtain local paracrine effects, and/or to simplify targeting strategies.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

Prologo JD,Hawkins M,Gilliland C,Chinnadurai R,Harkey P,Chadid T,Lee Z,Brewster L

doi

10.1016/j.crad.2016.01.005

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

307-11

issue

4

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(16)00010-6

journal_volume

71

pub_type

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