Abstract:
AIM:To examine whether Positron Emission Tomography Response Criteria in Solid Tumours (PERCIST) is useful to predict tumour response and prognosis of patients with oesophageal cancer who received neoadjuvant chemoradiotherapy (NACRT) followed by surgery. MATERIALS AND METHODS:This multicentre retrospective study included 60 patients with oesophageal cancer who underwent 2-[18F]-fluoro-2-deoxy-d-glucose positron-emission tomography/computed tomography (18F-FDG-PET/CT) before and after NACRT prior to surgery from January 2007 and June 2016. The correlation between pathological response and PERCIST was assessed by χ2 test. The prognostic significance was assessed by the Kaplan-Meier method and Cox regression analysis. RESULTS:There were 30 responders and 30 non-responders pathologically. The complete metabolic response (CMR), partial metabolic response (PMR), stable metabolic disease (SMD), and progressive metabolic disease (PMD) were seen in 22, 29, seven, and two patients, respectively. There was a significant correlation between pathological response and PERCIST (p<0.001). Forty patients showed eventual progression, and 20 patients were alive without progression between the start of NACRT and last clinical follow-up (median follow-up period; 27 months [range, 3-107]). Pathological stage and PERCIST were significant for progression-free survival (PFS; p=0.044 and 0.006, respectively) and also significant for overall survival (OS; p=0.009 and 0.001, respectively) at univariate analysis. Pathological lymph node staging was also significant for OS at univariate analysis (p=0.018). At multivariate analysis, PERCIST remained significant and independent for PFS (hazard ratio [HR]: 1.59, p=0.046) and OS (HR: 1.82, p=0.008). CONCLUSION:PERCIST may be useful for predicting tumour response and prognosis of patients with oesophageal cancer who received NACRT.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Nakajo M,Kitajima K,Kaida H,Morita T,Minamimoto R,Ishibashi M,Yoshiura Tdoi
10.1016/j.crad.2019.09.132subject
Has Abstractpub_date
2020-01-01 00:00:00pages
79.e9-79.e18issue
1eissn
0009-9260issn
1365-229Xpii
S0009-9260(19)30574-4journal_volume
75pub_type
杂志文章,多中心研究abstract::In the past four decades, a variety of methods for minimal or non-invasive diagnosis and treatment of breast cancer have been introduced. Although breast imaging has become more and more specific for diagnosis, specimen biopsy with histopathological confirmation is still necessary. Core-needle biopsy under ultrasound ...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.10.018
更新日期:2018-08-01 00:00:00
abstract::The gigantiform cementoma presents as multiple opacities in the tooth-bearing areas of the jaws. Sixteen cases are presented, six of British Negresses and 10 of Hong Kong Chinese females. The differential diagnosis and management are briefly reviewed. ...
journal_title:Clinical radiology
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doi:10.1016/s0009-9260(05)80082-0
更新日期:1992-05-01 00:00:00
abstract::In this report, we illustrate the imaging findings of diseases in the subperitoneal space of the broad ligament and sigmoid mesocolon and discuss the pathways of subperitoneal spread of disease. The subperitoneal space of the broad ligament and sigmoid mesocolon is continuous with that of the parietal peritoneum overl...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(98)80213-4
更新日期:1998-12-01 00:00:00
abstract::A histological review of 271 cases of nodular sclerosing Hodgkin's disease, patients presenting with clinical Stage I, II and III disease but not subjected to a staging laparotomy, has been undertaken. Cases were categorised according to the cytological appearances of the cellular nodules and the degree of sclerosis w...
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doi:10.1016/s0009-9260(83)80148-2
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abstract:AIMS:To report the outcomes of elective and emergency embolization of renal angiomyolipoma and describe an angiographic sign that will help localize the symptomatic aneurysm in emergency cases. MATERIALS AND METHODS:A retrospective review of all patients undergoing embolization of renal angiomyolipoma at a two centres...
journal_title:Clinical radiology
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doi:10.1016/j.crad.2008.02.005
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abstract::Renal artery stenosis (RAS) causes chronic, progressive ischaemic nephropathy and is the most common cause of secondary hypertension. Radiology plays a large part in the diagnosis, with a variety of imaging techniques available. Each has relative advantages and disadvantages depending on each unique clinical setting. ...
journal_title:Clinical radiology
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abstract:AIM:To assess the predictive value of the U classification and the significance of follow-up ultrasound in those managed conservatively. MATERIALS AND METHODS:A retrospective observational study was carried out among 1,465 patients who underwent thyroid ultrasound in 2016 at a teaching hospital in UK. Details regardin...
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80108-4
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2001.0767
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
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更新日期:2020-06-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(99)91086-3
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2000.0579
更新日期:2001-06-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(87)80388-4
更新日期:1987-01-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80060-5
更新日期:1986-09-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2011.08.009
更新日期:2012-02-01 00:00:00
abstract::Osteonecrosis is a relatively common condition, which may be idiopathic or secondary to a variety of clinical situations. It may involve the subarticular region of a joint, when it is commonly referred to as ischaemic necrosis, or the metaphyseal regions of long bones, when it is referred to as bone infarction. In bot...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2004.04.014
更新日期:2004-12-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2006.01.013
更新日期:2006-07-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.01.016
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2014.01.005
更新日期:2014-05-01 00:00:00
abstract::A communication between the left ascending lumbar vein and the left renal vein may be mistaken for a para-aortic mass on abdominal computed tomography due to a localised dilatation at the confluence of these veins. The use of contiguous closely collimated sections and the injection of intravenous contrast medium overc...
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pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80244-7
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journal_title:Clinical radiology
pub_type: 杂志文章,meta分析
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更新日期:2005-09-01 00:00:00
abstract::In order to estimate the rate of local complications of phlebography we studied a one-year series of 477 patients. Half of the patients were examined with a comparatively highly concentrated contrast medium and half with a more diluted one. Eight patients had local complications, verified by biopsy and/or thermography...
journal_title:Clinical radiology
pub_type: 杂志文章
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abstract::Neuronal migration anomalies form a spectrum of congenital brain malformations with a variety of clinical manifestations. The widespread use of MRI in the investigation of neurological symptoms, and particularly in the imaging of epilepsy, has made the correct recognition and interpretation of these disorders importan...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(96)80211-x
更新日期:1996-01-01 00:00:00
abstract::A randomized prospective trial was undertaken to compare the relative effectiveness of two commonly used bowel preparations (senna tablets and sodium picosulphate powder) administered to patients before they underwent out-patient intravenous urography. Their 'control' films were compared with plain 'kidneys, ureters, ...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1991-11-01 00:00:00
abstract:AIM:To demonstrate the value of pelvic magnetic resonance imaging (MRI) in mapping tumour extension after chemoradiotherapy and before anterior pelvic exenteration in patients with primary carcinoma of the urethra. MATERIALS AND METHODS:The Institutional Review Board approved and issued a waiver of informed consent fo...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2011.07.039
更新日期:2011-11-01 00:00:00
abstract:AIMS:To determine if the number of flecks of calcification retrieved at stereotaxic core needle biopsy or the number of core samples obtained containing calcification are related to biopsy sensitivity, and to determine how many calcifications or cores containing calcification the radiologist should aim to retrieve when...
journal_title:Clinical radiology
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doi:10.1053/crad.1999.0483
更新日期:2000-07-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.1999.0380
更新日期:2000-04-01 00:00:00
abstract:AIM:To determine whether radiographers are able to perform and interpret barium swallows and meals (BSM) to an acceptable standard. MATERIALS AND METHODS:A retrospective audit was performed of all radiographer-managed BSMs over a 4-year period in an acute hospital. Descriptive statistics were used to analyse patient d...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2009.04.008
更新日期:2009-08-01 00:00:00
abstract::Hip arthroplasty is an extremely common orthopaedic procedure and there is a wide array of implants that are in current use in the UK. The follow-up of patients who have undergone insertion of a hip prosthesis is shifting from a consultant-lead hospital service towards primary care. As this change in patient care cont...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2009.03.011
更新日期:2009-10-01 00:00:00