Abstract:
AIMS:Magnetic resonance colonography (MRC) is emerging as a potential complementary investigation for the diagnosis of colorectal cancer (CRC) and also for benign pathology such as diverticular disease. A meta-analysis reporting the use of MRC is yet to be performed. The aim of this study was to evaluate the diagnostic accuracy of MRC compared with the gold-standard investigation, conventional colonoscopy (CC). METHODS:A literature search was carried out to identify studies containing comparative data between MRC findings and CC findings. Quantitative meta-analysis for diagnostic tests was performed, which included the calculation of independent sensitivities, specificities, diagnostic odds ratios, the construction of summary receiver operating characteristic (SROC) curves, pooled analysis and sensitivity analysis. The study heterogeneity was evaluated by the Q-test using a random-effect model to accommodate the cluster of outcomes between individual studies. RESULTS:In all, 8 comparative studies were identified, involving 563 patients. The calculated pooled sensitivity for all lesions was 75% (95% CI: 47% to 91%), the specificity was 96% (95% CI: 86% to 98%) and the area under the ROC curve was 90% (weighted). On sensitivity analysis, MRC had a better diagnostic accuracy for CRC than for polyps, with a sensitivity of 91% (95% CI: 97% to 91%), a specificity of 98% (95% CI: 66% to 99%) and an area under the ROC curve of 92%. There was no significant heterogeneity between the studies with regard to the diagnostic accuracy of MRC for CRC. CONCLUSION:This meta-analysis suggests that MRC is an imaging technique with high discrimination for cases presenting with colorectal cancer. The exact diagnostic role of MRC needs to be clarified (e.g. suitable for an elderly person with suspected CRC). Further evaluation is necessary to refine its applicability and diagnostic accuracy in comparison with other imaging methods such as computed tomography colonography.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Purkayastha S,Tekkis PP,Athanasiou T,Aziz O,Negus R,Gedroyc W,Darzi AWdoi
10.1016/j.crad.2005.04.015subject
Has Abstractpub_date
2005-09-01 00:00:00pages
980-9issue
9eissn
0009-9260issn
1365-229Xpii
S0009-9260(05)00170-4journal_volume
60pub_type
杂志文章,meta分析abstract:AIM:To demonstrate the magnetic resonance imaging (MRI) appearances of intact and ruptured Trilucent TM implants with imaging and surgical correlation. The appearances of the implant transponder artefact are also described MATERIALS AND METHODS:A retrospective review of the MRI findings in 34 patients with bilateral s...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2001.0767
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journal_title:Clinical radiology
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journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-08-01 00:00:00
abstract::A prospective study, followed by a retrospective audit, was made of the radiographs and clinical features of 225 consecutive neonates with abdominal distension presenting during a period of 4 years. More than one major cause for the distension was found in a third of cases. Excluding cases of ano-rectal atresia, diagn...
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doi:10.1016/s0009-9260(05)82993-9
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doi:10.1016/j.crad.2015.01.007
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pub_type: 杂志文章,多中心研究
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更新日期:2011-08-01 00:00:00
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更新日期:2003-06-01 00:00:00
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更新日期:2019-01-01 00:00:00
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doi:10.1016/j.crad.2009.01.005
更新日期:2009-05-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(98)80315-2
更新日期:1998-10-01 00:00:00
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journal_title:Clinical radiology
pub_type:
doi:10.1016/s0009-9260(05)80871-2
更新日期:1991-09-01 00:00:00
abstract::The pre-operative images of three patients with biopsy proven esthesioneuroblastoma are presented. The role of computed tomography (CT) and magnetic resonance imaging (MRI) in the pre-operative determination of tumour extent is discussed. ...
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pub_type: 杂志文章
doi:10.1016/s0009-9260(05)83295-7
更新日期:1995-09-01 00:00:00
abstract::Gastrointestinal stromal tumours (GISTs) can lead to emergency situations, such as gastrointestinal bleeding, intestinal obstruction, and tumoural rupture with haemoperitoneum or peritonitis. In addition, if a GIST grows exophytically to a large size, it is often misdiagnosed as a tumour arising from adjacent organs. ...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
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abstract::Extramedullary haematopoiesis (EMH) refers to the formation of non-neoplastic blood cell lines outside the bone marrow and is a common incidental finding when patients with haematological disorders are imaged. EMH presenting as mass (tumefactive EMH) has long been a radiological conundrum as it resembles neoplasms. Se...
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abstract::Sixty patients admitted with a clinical diagnosis of pulmonary embolism underwent a prospective analysis of the value of lung ventilation/perfusion scintigraphy and lower limb colour flow venous Doppler. Twenty-two per cent of scintigrams gave a high probability of pulmonary embolus (PE) and 45% a low probability/norm...
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doi:10.1053/crad.2000.0436
更新日期:2000-05-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.crad.2015.11.007
更新日期:2016-03-01 00:00:00
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doi:10.1016/s0009-9260(05)80072-8
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journal_title:Clinical radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.crad.2004.01.011
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abstract::Intravenous urography is the standard screening test for renovascular hypertension but there is a significant incidence of false negative and false positive results. In an attempt to improve the detection rate, indomethacin was administered orally to nine patients with renal artery stenosis (proven by arteriography an...
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pub_type: 杂志文章
doi:10.1016/s0009-9260(81)80288-7
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2006.07.007
更新日期:2006-12-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1994-05-01 00:00:00
abstract:AIM:To assess the current practice of scaphoid fracture imaging (where initial scaphoid radiographs are normal) in the UK. MATERIALS AND METHODS:A survey monkey questionnaire was sent to 140 eligible NHS trusts derived from the NHS England database following exclusion of all non-acute and specialist centres. Four ques...
journal_title:Clinical radiology
pub_type: 杂志文章
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abstract:AIMS:To determine if the number of flecks of calcification retrieved at stereotaxic core needle biopsy or the number of core samples obtained containing calcification are related to biopsy sensitivity, and to determine how many calcifications or cores containing calcification the radiologist should aim to retrieve when...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.1999.0483
更新日期:2000-07-01 00:00:00