Abstract:
:In the past four decades, a variety of methods for minimal or non-invasive diagnosis and treatment of breast cancer have been introduced. Although breast imaging has become more and more specific for diagnosis, specimen biopsy with histopathological confirmation is still necessary. Core-needle biopsy under ultrasound guidance is the appropriate first choice for the diagnosis of most lesions. Fine-needle aspiration is of interest for identification of the presence of metastatic disease in abnormal lymph nodes. For microcalcifications, vacuum-assisted biopsy is recommended, especially with stereotactic guidance. In recent years different therapeutic techniques have been developed for the treatment of solid lesions, including breast cancer. Certainly, with the improvement of technology and medical scientific progress, it is becoming more common to use minimal- or non-invasive therapies. The proposed minimally invasive techniques may offer complete treatment of breast cancer, with better cosmetic results, less psychological stress, and shorter hospital stays. In this article, the strengths and weaknesses of the different diagnostic and therapeutic techniques are presented, and promising techniques for the future are discussed.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Sanderink WBG,Mann RMdoi
10.1016/j.crad.2017.10.018subject
Has Abstractpub_date
2018-08-01 00:00:00pages
724-734issue
8eissn
0009-9260issn
1365-229Xpii
S0009-9260(17)30513-5journal_volume
73pub_type
杂志文章,评审abstract::18F-sodium fluoride (NaF) is a PET bone imaging agent and is commonly used in imaging patients with cancer; however, similar to technetium-99m medronic acid (99mTc-MDP), it can be useful in the evaluation of benign bone and joint conditions. NaF is an excellent bone-seeking agent with high bone uptake due to rapid sin...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2018.09.007
更新日期:2019-02-01 00:00:00
abstract::Two paediatric cases of acquired ossification of the cervical anterior longitudinal ligament are described. This has not been previously reported in childhood. The first was associated with corrosive ingestion requiring oesophagectomy and colonic interposition and the second with acute lymphoblastic leukaemia initiall...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)82993-9
更新日期:1995-02-01 00:00:00
abstract:AIMS:Magnetic resonance colonography (MRC) is emerging as a potential complementary investigation for the diagnosis of colorectal cancer (CRC) and also for benign pathology such as diverticular disease. A meta-analysis reporting the use of MRC is yet to be performed. The aim of this study was to evaluate the diagnostic...
journal_title:Clinical radiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.crad.2005.04.015
更新日期:2005-09-01 00:00:00
abstract:AIM:To investigate the relationship between mammographic breast density (MGD) and background parenchymal enhancement (BPE) at breast MRI and histopathological features of invasive breast cancers. MATERIALS AND METHODS:A total of 178 women with unilateral invasive breast cancer who preoperatively underwent mammography ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.02.017
更新日期:2015-07-01 00:00:00
abstract:AIM:To determine the effect of two different contrast agent volumes on quantitative and semi-quantitative vascular parameters as measured by perfusion computed tomography (CT) in colorectal cancer. MATERIALS AND METHODS:Following ethical approval and informed consent, eight prospectively recruited patients with proven...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2008.08.018
更新日期:2009-04-01 00:00:00
abstract:AIM:To quantify the volume of bone marrow oedema surrounding focal bone lesions and to identify its relevance relative to diagnosis. METHODS:Three hundred and eighty-eight of 1456 patients included in the orthopaedic oncology database who underwent magnetic resonance imaging (MRI) demonstrated bone marrow oedema and w...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2006.07.007
更新日期:2006-12-01 00:00:00
abstract::We report the findings of computed tomography and magnetic resonance imaging in two cases of surgically proven benign cavernous haemangiomas of the mediastinum. Both techniques produced similar results, although both were non-diagnostic for haemangioma as was percutaneous needle biopsy, which was performed in one pati...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81585-5
更新日期:1991-02-01 00:00:00
abstract::Pelvic phleboliths were demonstrated in 1000 subjects aged 16--79 years (mean 42.1, s.d. 12.7). They occurred in 44.2% of the subjects, in 37.3% of the males and 50.1% of the females. Among subjects between the ages of 35 and 54, phleboliths occurred more frequently in the females than in the males. In addition the ol...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(80)80095-x
更新日期:1980-01-01 00:00:00
abstract::Three patients with pancreatic clonorchiasis were examined with endoscopic retrograde pancreatography. On each of the three cases there was diffuse irregular dilatation of tributaries of the pancreatic duct in the pancreatic tail. The main pancreatic duct and tributaries draining into the body and head portion were no...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80967-5
更新日期:1990-03-01 00:00:00
abstract:AIM:To determine the follow-up protocol for interval assessment of patients following radical nephrectomy for renal cell cancer and to compare them with the recommendations proposed in the literature. METHODS:Consultant urologists across Britain and Ireland completed a postal questionnaire. One follow-up mailing was u...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2006.05.006
更新日期:2006-10-01 00:00:00
abstract::A wide range of pathologies may arise from the submandibular space (SMS) or submandibular gland (SMG) in children. We review herein the normal anatomy of the SMS and describe the role of imaging in the evaluation of SMS lesions. A schematic approach for the categorisation of SMS pathology based on imaging characterist...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2015.03.003
更新日期:2015-07-01 00:00:00
abstract::In order to assess the validity of quantitative duplex Doppler measurements of portal vein flow, 10 patients with proven diffuse liver disease and portal hypertension were examined serially by two independent observers over a 3 month period. Multiple measurements of the portal vein were made using a consistent techniq...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81237-1
更新日期:1993-11-01 00:00:00
abstract::Thw radiological appearances found in the pelvis and hip joints in 79 patients with cerebral palsy, aged 5--16 years, have been studied. These findings have been recorded and correlated with the clinical severity and distribution of the disease. Subluxation of the hip joints was found in 14% and dislocation in a furth...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(77)80099-8
更新日期:1977-03-01 00:00:00
abstract::A review is made of the assessments of the magnitude of harm arising from diagnostic X-ray exposures. Factors influencing the effect of radiation are described. Financial values are estimated for the harm, both from carcinogenesis and genetic injury. The chance of injury to an individual patient is small and the numbe...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(84)80170-1
更新日期:1984-09-01 00:00:00
abstract:AIM:To evaluate whether radiologists can accurately differentiate Wilms' tumours from other paediatric abdominal masses with renal involvement using modern imaging methods alone. METHODS:From February 1993 to June 1997, 23 patients presented to the Paediatric Oncology Service at The Royal Hospital for Sick Children, E...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(99)90563-9
更新日期:1999-05-01 00:00:00
abstract::Thirty-seven instant (unprepared) barium enemas in 30 patients with proven Crohn's colitis were reviewed. Plain films in 28 indicated that confluence or discontinuity of the colitis did not substantially alter the pattern of faecal residue. In only one patient was residue found overlying active mucosal disease. Aphtho...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81454-0
更新日期:1993-05-01 00:00:00
abstract:AIM:Recent protein expression profiling of breast cancer has identified specific subtypes with clinical, biological, and therapeutic implications. The aim of this study was to identify the mammographic correlates of these novel molecular classes of invasive breast cancer. MATERIALS AND METHODS:The mammographic finding...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2008.06.006
更新日期:2008-11-01 00:00:00
abstract::Peri-articular erosions have been described in primary and secondary hyperparathyroidism. Seventy-two patients with chronic renal failure were reviewed for the presence of erosions. These were found in 15 patients while another 20 patients showed other evidence of secondary hyperparathyroidism. The distribution of ero...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(82)80334-6
更新日期:1982-01-01 00:00:00
abstract::Congenital bronchial atresia (CBA) is a rare anomaly that results from a congenital focal obliteration of a proximal segmental or subsegmental bronchus with the normal development of distal structures. The short atretic segment leads to accumulation of mucus within the distal bronchi to form a bronchocoele and underve...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(99)91002-4
更新日期:1999-03-01 00:00:00
abstract:AIM:The aim of this study was to assess the CT manifestations of bronchocentric granulomatosis. SUBJECTS AND METHODS:The CT results of five patients with bronchocentric granulomatosis were retrospectively analysed. The patients ranged from 20 to 72 years of age and included three men and two women. The diagnosis of br...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.1999.0380
更新日期:2000-04-01 00:00:00
abstract::Thirty patients with testicular teratomas were examined by computed tomography (CT), lymphangiography and chest X-rays/tomography and the role of each investigation in the staging and management of these tumours is examined. It is suggested that CT should be the primary investigation of the abdomen in patients with te...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(81)80338-8
更新日期:1981-11-01 00:00:00
abstract::The uncinate process of the pancreas has been assessed in 106 consecutive patients without pancreatic disease in order to establish normal features. The process measures approximately 1 X 1.3 cm in size, is frequently inseparable from the superior mesenteric vein without contrast enhancement and can adopt a number of ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80024-2
更新日期:1988-03-01 00:00:00
abstract:AIM:To assess the effectiveness and economy of routinely using commercially available in-plane bismuth shielding during CT scanning of the chest and brain. METHODS AND MATERIALS:Forty patients were scanned with thermoluminescent dosemeters (TLDs) in situ to measure the radiation dose to the thyroid and eye during CT s...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2003.10.016
更新日期:2004-05-01 00:00:00
abstract::Myeloproliferative neoplasms (MPNs) are a heterogeneous group of haematological disorders including polycythaemia vera (PV), essential thrombocythaemia (ET), primary myelofibrosis (PMF), and chronic myeloid leukaemia (CML). These disorders show large overlap in genetic and clinical presentations, and can have many dif...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.05.014
更新日期:2017-10-01 00:00:00
abstract::Infiltrating syringomatous adenoma is a recently-recognized locally-invasive breast neoplasm which clinically may mimic carcinoma. We describe bilateral syringomatous adenomata in a screened patient, indistinguishable from carcinoma on mammography and ultrasound examination. The clinical and pathological features whic...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81219-x
更新日期:1993-01-01 00:00:00
abstract::Between January 1949 and June 1955 a clinical trial was held in which patients with operable breast carcinoma were subjected to a radical mastectomy and then randomised to either have immediate post-operative radiotherapy (radiated group) or delayed radiotherapy on recurrence (watched group). Data relating to the 1461...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(89)80099-6
更新日期:1989-03-01 00:00:00
abstract:AIM:To identify magnetic resonance imaging (MRI) features differentiating high-grade (>5% round-cell component) from low-grade myxoid liposarcomas (LPS) (≤5% round-cell component). MATERIALS AND METHODS:Informed consent was waived. Patients with myxoid LPS and MRI before biopsy, neoadjuvant therapy, and surgery were i...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.01.016
更新日期:2017-07-01 00:00:00
abstract:AIM:To assess the effect of the presence and locality of symptomatic lower-limb deep vein thrombosis (DVT) on mortality and morbidity following contrast venography (CV), the reference standard for diagnosing below-knee DVT, with a view to determining the prevalence of recurrent episodes of DVT and post-thrombotic syndr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.12.014
更新日期:2016-04-01 00:00:00
abstract::As part of the development of an auditing system for this department, a pilot study was designed to audit the quality of the product leaving the department. One hundred and six patient investigations were reviewed. For each investigation 26 items which were considered to reflect the quality of information on the reque...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81274-7
更新日期:1991-11-01 00:00:00
abstract::This report describes a comparison of combination chemotherapy (CHOP) with total body irradiation (TBI) in the management of Stages III and IV Grade 2 non-Hodgkin's lymphoma. This prospective randomised study was carried out by the BNLI between 1974 and 1978. One hundred and fourteen previously untreated patients were...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(81)80186-9
更新日期:1981-09-01 00:00:00