Abstract:
:This report describes a comparison of combination chemotherapy (CHOP) with total body irradiation (TBI) in the management of Stages III and IV Grade 2 non-Hodgkin's lymphoma. This prospective randomised study was carried out by the BNLI between 1974 and 1978. One hundred and fourteen previously untreated patients were accepted: 66 received CHOP and 48 TBI. Complete remission was obtained in 39% of patients treated with CHOP and 23% with TBI. This difference is not significant. However, when comparison is stratified for Stage III disease the survival of the CHOP-treated group is statistically significant (chi(2) = 4.125: 0.05 greater than P greater than 0.025). This difference in favour of CHOP is most marked in patients with poorly differentiated histology. Only 46% of patients receiving CHOP remain alive at the time of this report. There is urgent need for more effective treatment in the management of this type of lymphoma.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Pettingale KWdoi
10.1016/s0009-9260(81)80186-9subject
Has Abstractpub_date
1981-09-01 00:00:00pages
553-6issue
5eissn
0009-9260issn
1365-229Xpii
S0009-9260(81)80186-9journal_volume
32pub_type
临床试验,杂志文章,随机对照试验abstract:AIM:To determine the prevalence and association of mesenteric panniculitis (MP) in a group of patients with non-Hodgkin's lymphoma (NHL) compared to control group. MATERIALS AND METHODS:We retrospectively evaluated computed tomography (CT) and combined positron-emission tomography (PET) with CT examinations of a total...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.05.008
更新日期:2017-10-01 00:00:00
abstract:AIM:To evaluate the efficacy and safety of internally cooled wet (ICW) electrodes, which provide interstitial infusion of saline and intra-electrode cooling simultaneously, in the percutaneous radiofrequency ablation (RFA) of liver metastases from colorectal cancer. MATERIALS AND METHODS:From February 2008 to October ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2011.08.009
更新日期:2012-02-01 00:00:00
abstract::Left ventriculography with selective coronary angiography was performed on 13 patients with acute myocardial infarcts complicated by cardiogenic shock of left ventricular failure and hypotension. Twelve patients (92-3%) tolerated the procedure well. Irreversible ventricular fibrillation resulting in death occurred in ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(77)80105-0
更新日期:1977-03-01 00:00:00
abstract:AIM:To determine the follow-up protocol for interval assessment of patients following radical nephrectomy for renal cell cancer and to compare them with the recommendations proposed in the literature. METHODS:Consultant urologists across Britain and Ireland completed a postal questionnaire. One follow-up mailing was u...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2006.05.006
更新日期:2006-10-01 00:00:00
abstract:AIM:To describe the radiological appearances of immune reconstitution inflammatory syndrome (IRIS) in human immunodeficiency virus (HIV)-infected patients with mycobacterial infections starting highly active anti-retroviral therapy (HAART). MATERIALS AND METHODS:Five consecutive HIV infected patients with IRIS due to ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2003.12.002
更新日期:2004-06-01 00:00:00
abstract::Fibrous dysplasia affecting the spine is unusual. A further 11 cases are reported and the radiological features are described. The complications and difficulties with the diagnosis of this condition are discussed. ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80222-8
更新日期:1988-09-01 00:00:00
abstract::Radiologically demonstrable abnormalities of the duodenum are common in cystic fibrosis and are most prevalent in the second part of the duodenum. Out of 14 upper gastrointestinal barium studies performed on patients with cystic fibrosis over a period of 10 years, radiographic abnormalities of the duodenum were found ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(83)80168-8
更新日期:1983-09-01 00:00:00
abstract::The clinical and radiological presentation of four cases of spontaneous aorto-caval fistula is described. This is an unusual complication of an abdominal aortic aneurysm and presents with abdominal pain, a pulsatile abdominal mass and an abdominal bruit. Our cases illustrate the variable clinical presentation, outline...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(83)80432-2
更新日期:1983-11-01 00:00:00
abstract::A prospective randomised trial was performed to examine the value of ureteric compression in intravenous urography. Calyceal distension improved during the urogram in 68% of kidneys when compression was used, in contrast to an improvement of 43% in patients not receiving compression. In both heavy patients and those w...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(87)80026-0
更新日期:1987-03-01 00:00:00
abstract:AIM:To measure contrast-to-noise ratios of liver lesions on conventional enhanced and digitally subtracted multidetector row computed tomography (CT) images. MATERIALS/METHODS:This study was approved by our hospital internal review board (IRB) and all collected data were evaluated in a Health Insurance Portability and...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2009.03.013
更新日期:2009-11-01 00:00:00
abstract:AIMS:To determine if the number of flecks of calcification retrieved at stereotaxic core needle biopsy or the number of core samples obtained containing calcification are related to biopsy sensitivity, and to determine how many calcifications or cores containing calcification the radiologist should aim to retrieve when...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.1999.0483
更新日期:2000-07-01 00:00:00
abstract::Radiographs of the shoulder girdle were examined in 180 women who attended the breast follow-up clinic at the Department of Radiotherapy, Edinburgh. These comprised 52 controls who had been treated by radical mastectomy alone and 128 patients who had received post-operative X-ray therapy. The significance of osteoporo...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(77)80134-7
更新日期:1977-01-01 00:00:00
abstract::Currarino et al. in 1981 described an association between an anterior sacral defect, congenital anorectal stenosis or another type of low anorectal malformation and a presacral mass. We are only aware of one previous report in the English literature of the association of a rectovaginal fistula with this triad and to o...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81859-8
更新日期:1994-04-01 00:00:00
abstract::The findings in 50 patients examined by computed tomography (CT) of the pituitary fossa are described. The appearances in 43 were judged to be abnormal, four were normal and three were 'doubtful'. Abnormal features included deviation of the pituitary stalk (seven), localised increased enhancement after intravenous inj...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(84)80094-x
更新日期:1984-07-01 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) has spread fast and extensively around the world, with significant mortality and morbidity. As this is a respiratory infection, chest radiography and computed tomography (CT) are important imaging techniques in the work-up of this disease. Given its highly infectious nature, cross-i...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2020.03.028
更新日期:2020-06-01 00:00:00
abstract::A wide spectrum of congenital and acquired abnormalities can affect the superior vena cava (SVC). Congenital anomalies can present either as incidental findings or be associated with underlying cardiac abnormalities; these include left-sided or double SVCs and anomalous venous drainages. Acquired conditions involving ...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2007.04.001
更新日期:2007-09-01 00:00:00
abstract::We reviewed our experience of the therapeutic role of radiology in Budd-Chiari syndrome. Patients with stenosis and/or occlusion of the main hepatic veins and/or inferior vena cava (IVC) are suitable for radiological intervention (35% in our series). Eighteen patients (mean age 37.4 years) have undergone radiological ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(96)80005-5
更新日期:1996-11-01 00:00:00
abstract:AIM:To evaluate the safety, efficacy, and long-term outcomes of ultrasound-guided radiofrequency ablation (RFA) for the treatment of primary papillary thyroid microcarcinoma (PTMC). MATERIALS AND METHODS:A total of 37 patients with 38 PTMC nodules underwent RFA at a power of 20 W between September 2014 and December 20...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2019.05.012
更新日期:2019-09-01 00:00:00
abstract::It is well recognized that a negative mammogram report does not exclude the presence of breast carcinoma. This study examines the accuracy of mammography in patients with palpable breast cancer. In particular, the study evaluates the reasons underlying negative mammography in breast cancer. All patients with Paget's d...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)83454-3
更新日期:1994-02-01 00:00:00
abstract:UNLABELLED:This review considers the process of contracting for a picture archiving and communication system (PACS) using the private finance initiative (PFI) managed service route. The PFI process is reviewed and the advantages and disadvantages of a managed service detailed. During contract negotiations several areas...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1053/crad.2001.0901
更新日期:2002-03-01 00:00:00
abstract:AIM:The purpose of this study was to describe the mammographic findings of localized foreign body granulomas in women who were injected with a foreign body in the cervicofacial area to flatten wrinkles. MATERIALS AND METHODS:The teaching files of our institutions were searched, and nine mammograms of migrated foreign ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2004.03.003
更新日期:2004-09-01 00:00:00
abstract::Aneurysm of the ductus arteriosus has been reported in children more frequently than in adults [1-4]. The rarity of the lesion explains the low rate of recognition by the radiologist, especially because symptoms are non-specific in most cases. Clinically and radiologically, aneurysm of the ductal diverticulum can be c...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(97)80279-6
更新日期:1997-03-01 00:00:00
abstract::Nine patients with bullous emphysema for which surgery was being considered have been investigated with computed tomography (CT). In six out of nine patients (67%) CT showed more extensive disease or bilateral disease where only unilateral was suspected from postero-anterior and lateral chest radiographs. Only one pat...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(84)80232-9
更新日期:1984-01-01 00:00:00
abstract::Thirty-eight patients with an advanced ovarian cancer (FIGO stage III and IV) were randomly allocated to treatment, either with melphalan (M) or a combination of adriamycin, 5-fluorouracil and cyclophosphamide (CAF) to determine the effect on survival. Actuarial survival of the two treatment groups was the same but th...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(82)80049-4
更新日期:1982-03-01 00:00:00
abstract::Mycobacterial infection is re-emerging as a major health care concern. Although Mycobacterium tuberculosis(MTB) is still the most important pathogen, atypical mycobacterium (AMB) infections are becoming increasingly common. We present a pictorial review of the imaging features of these infections in the chest, abdomen...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1053/crad.2001.0755
更新日期:2001-07-01 00:00:00
abstract::A case of multifocal xanthogranulomatous pyelonephritis (XPN) in childhood diagnosed by ultrasound, computed tomography and needle biopsy is described. Following antibiotic therapy, ultrasound and a DMSA renal scintiscan showed no discernible scarring and restoration of function. This has not been previously described...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81705-2
更新日期:1990-05-01 00:00:00
abstract::The incidence of renal cell carcinoma is increasing and image-guided radiofrequency ablation (RFA) is emerging as a safe and effective primary treatment. Therefore, it is essential for radiologists to appreciate the varied computed tomography (CT) imaging features following RFA. Prompt recognition of residual or recur...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2007.07.002
更新日期:2008-02-01 00:00:00
abstract::Ongoing research on malignant and normal cell biology has substantially enhanced the understanding of the biology of cancer and carcinogenesis. This has led to the development of methods to image the evolution of cancer, target specific biological molecules, and study the anti-tumour effects of novel therapeutic agent...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2015.06.082
更新日期:2015-10-01 00:00:00
abstract:AIM:To evaluate the clinical impact of combined 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography/computed tomography (PET/CT) brain imaging performed in selected patients with cognitive impairment at a tertiary referral centre in the UK, and to assess the accuracy of FDG PET/CT to correctly establish...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2016.08.003
更新日期:2017-01-01 00:00:00
abstract::There have been significant advances in the diversity and effectiveness of hearing technologies in recent years. Implanted auditory devices may be divided into those that stimulate the cochlear hair cells (bone conduction devices and middle ear implants), and those that stimulate the neural structures (cochlear implan...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.03.002
更新日期:2018-01-01 00:00:00