The prognostic significance of cellular subtypes in nodular sclerosing Hodgkin's disease: an analysis of 271 non-laparotomised cases (BNLI report no. 22).

Abstract:

:A histological review of 271 cases of nodular sclerosing Hodgkin's disease, patients presenting with clinical Stage I, II and III disease but not subjected to a staging laparotomy, has been undertaken. Cases were categorised according to the cytological appearances of the cellular nodules and the degree of sclerosis was examined. Cytological subtypes with extensive and easily recognised areas of lymphocyte depletion or numerous pleomorphic Hodgkin's cells were associated with a decreased survival and clinical stage did not appear to be a good indicator of prognosis in these patients. Pronounced nodal sclerosis was associated with a higher relative frequency of mediastinal disease and the lymphocyte-depleted cytological subtypes.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

Bennett MH,MacLennan KA,Easterling MJ,Vaughan Hudson B,Jelliffe AM,Vaughan Hudson G

doi

10.1016/s0009-9260(83)80148-2

subject

Has Abstract

pub_date

1983-09-01 00:00:00

pages

497-501

issue

5

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(83)80148-2

journal_volume

34

pub_type

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