Abstract:
:Cytomegalovirus (CMV) is the most commonly transmitted virus in utero with a prevalence of up to 1.5%. The infection has potentially debilitating and devastating consequences for the infected fetus, being a leading cause for neurological disability worldwide. Once acquired, it often goes undetected with only an assumed 10% of infected neonates displaying the classic clinical or imaging features. Viral DNA polymerase chain reaction (PCR) of saliva or urine obtained within the first 21 days of life is required to make the diagnosis. As the majority of infected neonates are initially asymptomatic, diagnosis is often delayed. An abnormal routine neonatal hearing test and characteristic antenatal cranial ultrasound imaging findings may raise the suspicion of congenital CMV (cCMV) in the asymptomatic group. Ultimately, the aim is to facilitate early diagnosis and timely treatment. In this article, we highlight diagnostic and treatment challenges of the commonest congenital infection, we present the current available central nervous system imaging severity grading systems, and highlight the need for an internationally agreed diagnostic grading system that can aid treatment decision-making.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Gaur P,Ffrench-Constant S,Kachramanoglou C,Lyall H,Jan Wdoi
10.1016/j.crad.2020.02.009subject
Has Abstractpub_date
2020-08-01 00:00:00pages
644.e7-644.e16issue
8eissn
0009-9260issn
1365-229Xpii
S0009-9260(20)30078-7journal_volume
75pub_type
杂志文章,评审abstract:AIM:To evaluate the usefulness of pseudo-continuous arterial spin labelling (pCASL) imaging in grading and differentiating histological subtypes of meningiomas. MATERIALS AND METHODS:In this prospective study, conventional magnetic resonance imaging (MRI) with contrast-enhanced T1-weighted images and pCASL were acquir...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.08.005
更新日期:2018-02-01 00:00:00
abstract::Biochemical, radiological and histological indicators of dialysis bone disease were studied before, 6 months (58 patients) and 12 months (48 patients) after starting treatment with 1 alpha-OH D3. Radiographic healing of subperiosteal erosions was seen after 6 months in 60% and after 12 months in 77% of affected patien...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(82)80330-9
更新日期:1982-01-01 00:00:00
abstract:AIM:To evaluate the predictive role of radiomics based on computed tomography (CT) in discriminating focal organising pneumonia (FOP) from peripheral lung adenocarcinoma (LA). MATERIALS AND METHODS:Institutional research board approval was obtained for this retrospective study. One hundred and seventeen patients with ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2018.08.014
更新日期:2019-01-01 00:00:00
abstract:AIM:To compare the performance of axial images of the ankle joint on three-dimensional (3D) volume isotropic turbo spin echo acquisition (VISTA) with that of two-dimensional (2D) fast spin echo (FSE) T2-weighted images for the diagnosis of anterior talofibular ligament (ATFL) injury. MATERIALS AND METHODS:This retrosp...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.12.007
更新日期:2016-04-01 00:00:00
abstract:AIM:This prospective study was performed to establish the correlation between colour Doppler ultrasound (US) observations and venography in detecting catheter-related thrombosis. METHOD:Forty-four patients with subclavian venous catheters were studied. The sensitivity and specificity of colour Doppler US was determine...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)83313-6
更新日期:1995-10-01 00:00:00
abstract:AIM:To compare combined 2-[18F]-fluoro-2-deoxy-d-glucose (FDG)-positron-emission tomography (PET) and cardiac magnetic resonance imaging (CMR) for the diagnosis and therapy monitoring of cardiac sarcoidosis (CS). MATERIALS AND METHODS:Eighty patients with sarcoidosis and a suspicion of CS who underwent PET and CMR wer...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2018.09.015
更新日期:2019-01-01 00:00:00
abstract:AIM:To assess the rate of upgrade in our screening population to determine whether open excision biopsy of mucocoele-like lesions (MLL) is still required. MATERIALS AND METHODS:A retrospective review of the breast screening database from 1999-2014 was performed. RESULTS:MLL were identified on core biopsy in 113 women...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.06.012
更新日期:2017-11-01 00:00:00
abstract::Twenty-seven patients with a T1 or T2 N0M0 breast carcinoma were treated by local excision of the lump followed by radical radiotherapy, using orthovoltage X-rays. The crude survival rate was 100% at three years, 92% at five years, 95% at 10 years. The local recurrence rate was 8% at three years, 12% at five years, 10...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(81)80246-2
更新日期:1981-01-01 00:00:00
abstract:AIM:To evaluate the value of magnetic resonance (MR) diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADC) maps in the diagnosis of intraparenchymal epidermoid cysts (ECs). MATERIALS AND METHODS:Six cases of histopathologically proven intraparenchymal ECs were studied. All patients were examined w...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2008.01.008
更新日期:2008-07-01 00:00:00
abstract:AIM:To evaluate the image quality of contrast-enhanced chest computed tomography (CT) with low tube voltage settings using an iterative reconstruction algorithm (iDose4) and standard dose filtered back projection (FBP) CT in patients with normal body mass index (BMI). MATERIALS AND METHODS:Eighty patients with normal ...
journal_title:Clinical radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.crad.2012.12.009
更新日期:2013-05-01 00:00:00
abstract:AIM:To investigate the utility of diffusion-weighted (DW) magnetic resonance imaging (MRI) in the diagnosis of abdominal wall endometrioma (AWE) and to compare the ADC (apparent diffusion coefficient) values of AWE with those of the uterine endometrium during two different phases of the menstrual cycle. MATERIALS AND ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2013.08.015
更新日期:2014-02-01 00:00:00
abstract:AIM:To determine the diagnostic yield of each of three core passes when sampling abnormal lymph nodes in patients presenting with breast cancer. MATERIALS AND METHODS:All patients suspected of having breast cancer had axillary ultrasound as part of initial assessment. Radiologically abnormal nodes (cortical thickness ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2011.10.006
更新日期:2012-05-01 00:00:00
abstract:AIM:To perform a retrospective review of all the conventional radiographic and magnetic resonance imaging (MRI) studies performed in patients with early postoperative pain following cobalt-chrome metal-on-metal total hip arthroplasty. METHODS:A retrospective review of the radiology, surgical findings and histology in ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2007.07.012
更新日期:2008-01-01 00:00:00
abstract::The aim of this study was to determine the incidence and cause of axillary lymphadenopathy detected by screening mammography and to devise a management protocol for this pathology. In a retrospective study of 95,806 consecutive screening mammograms, 37 cases of 'pathological' axillary nodes were identified using two o...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(97)80008-6
更新日期:1997-06-01 00:00:00
abstract::We have assessed the diagnostic accuracy of a flat or concave left mid-cardiac border (the region of the left atrial appendage) on conventional postero-anterior chest radiographs as a predictor of the presence of thrombi in the left atrium or its appendage in 80 patients with rheumatic mitral stenosis who subsequently...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80543-4
更新日期:1991-05-01 00:00:00
abstract::Sepsis with gas-forming organisms, e.g. Clostridium perfringens and anaerobic streptococci occurred in three of 120 liver-transplant recipients (2.5%). The diagnosis was made in all three patients by bedside ultrasound, before blood cultures revealed bacterial growth. Floating high amplitude echoes within the extra- a...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80568-9
更新日期:1991-06-01 00:00:00
abstract::Radiation therapy of the length of the spinal column presents various clinical and physical problems. The completed plan may be complicated to set up, be time-consuming and require daily variation to achieve reasonable dose homogeneity. A case of medulloblastoma is used to illustrate the steps in producing a plan for ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80126-4
更新日期:1985-03-01 00:00:00
abstract::In this George Simon Lecture, I have tried to present a simplistic yet philosophical approach to the physiological processes of adaptation of circulatory and respiratory function in response to pathophysiological challenge. The objective of the body is to achieve a normal ventilation-perfusion ratio of 1 in order to o...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80092-1
更新日期:1985-03-01 00:00:00
abstract::Iocetamic acid (Cholebrin) and calcium ipodate (Solubiloptin) were randomly allocated to two groups of 50 patients. Each patient completed a detailed questionnaire for side effects. There was no significant difference between the contrast media in their ability to opacify the gallbladder. Cholebrin was superior to Sol...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(78)80046-4
更新日期:1978-09-01 00:00:00
abstract:AIM:To assess the effect of changing from an "appointment" to a "same-day" ultrasound (US) service on referral pattern, departmental workload, and patient satisfaction. MATERIALS AND METHODS:To reduce US waiting time of 3 weeks for routine examinations, a "same-day" service was started for outpatients and general prac...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2009.09.009
更新日期:2010-01-01 00:00:00
abstract::Thirty-five cases of 'Q' fever have been admitted and confirmed serologically over the past 20 years. Thirty-two of these cases had chest films on admission, and lung changes were present in 87%. The lung changes were: 1. Multiple round segmental consolidations, 5--10 cm in diameter, of ground glass density and usuall...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(78)80092-0
更新日期:1978-07-01 00:00:00
abstract::Five adult females with swelling, tenderness and similar sclerotic changes of the sternal end of the clavicle are presented. They were recognised during a 10-year period, suggesting that the condition is rare and may be misdiagnosed. In three patients strain of the sternoclavicular joint seemed to be an aetiological f...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80010-6
更新日期:1985-01-01 00:00:00
abstract:AIM:To determine whether a combination of clinical factors, the future liver remnant (FLR) ratio, and hepatic uptake of gadoxetic acid can be used to predict post-hepatectomy liver failure (PHLF) and other major complications (OMC). MATERIALS AND METHODS:Sixty-five consecutive patients who underwent pre-hepatectomy ga...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.02.004
更新日期:2017-07-01 00:00:00
abstract:AIM:To identify the differences between ultrasound (US) features of parathyroid carcinoma (PC) and benign parathyroid (BP) lesions in patients with primary hyperparathyroidism (PHPT). MATERIAL AND METHODS:Twenty-one patients with PC and 64 consecutive patients with BP, whose diagnoses were confirmed at surgery, were e...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2019.10.004
更新日期:2020-03-01 00:00:00
abstract:AIM:To compare excretory phase, helical computed tomography (CT) with intravenous (IV) urography for evaluation of the urinary tract in patients with painless haematuria. MATERIALS AND METHODS:Ninety-one out-patients had IV urography followed by helical CT limited to the urinary tract. Both IV urograms and CT images w...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(02)00464-6
更新日期:2003-04-01 00:00:00
abstract:AIM:To review the outcome of further assessment of breast abnormalities detected incidentally by multidetector computed tomography (MDCT) and to determine whether any MDCT imaging features were predictive of malignancy. MATERIAL AND METHODS:The outcome of 34 patients referred to the Primrose Breast Care Unit with brea...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2009.01.005
更新日期:2009-05-01 00:00:00
abstract::There is a pressing clinical need to develop accurate, efficient non-contrast magnetic resonance angiography (NC-MRA) techniques. Our efforts in the field have focused on a novel non-subtractive technique called quiescent-interval slice-selective (QISS) MRA. Compared with other NC-MRA techniques, QISS has the advantag...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.12.003
更新日期:2019-01-01 00:00:00
abstract::The accuracy of high field, endorectal MRI in the staging of localized prostate cancer has been the focus of many previous reports. We present our findings with a mid-field magnet. Twenty-two patients with clinically localized prostate cancer were prospectively staged with endorectal MRI using a 0.5 T magnet. All pati...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(96)80133-4
更新日期:1996-08-01 00:00:00
abstract::Two paediatric cases of acquired ossification of the cervical anterior longitudinal ligament are described. This has not been previously reported in childhood. The first was associated with corrosive ingestion requiring oesophagectomy and colonic interposition and the second with acute lymphoblastic leukaemia initiall...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)82993-9
更新日期:1995-02-01 00:00:00
abstract:AIM:To validate an imaging protocol for the management of solitary central cartilage tumours (CCTs) of the proximal humerus and around the knee. MATERIALS AND METHODS:Over a 10-year period, 387 patients were identified with a CCT in the proximal humerus, distal femur, and proximal tibia, who were referred to a single ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2019.08.017
更新日期:2019-12-01 00:00:00