Sulfated components of enveloped viruses.

abstract：:Cloned DNA from the P155 mutant of polyoma virus transforms cells in culture as efficiently as wild-type DNA, but has a much lower tumorigenic potential when injected into newborn rats. Like cells transformed by wild-type DNA, cells transformed by the mutant DNA grow in low serum concentrations, form colonies in agar ...

journal_title：Journal of virology

authors： Gelinas C,Chartrand P,Bastin M

更新日期：1982-09-01 00:00:00

abstract：:The effect of 5-bromodeoxyuridine (BrdU) on vaccinia virus-induced polypeptide synthesis in BSC-1 cells has been investigated. Most virus-induced pre- and post-replicative polypeptides were synthesized in concentrations of 5-bromodeoxyuridine that inhibited virus growth. The synthesis of a few post-replicative polypep...

journal_title：Journal of virology

authors： Pennington TH

更新日期：1976-06-01 00:00:00

abstract：:The membrane glycoproteins G1 and G2 of Uukuniemi virus, a member of the Bunyaviridae family, are cotranslationally cleaved from a common precursor in the endoplasmic reticulum (ER). Here, we show that newly made G1 and G2 associate transiently with calnexin and calreticulin, two lectins involved in glycoprotein foldi...

journal_title：Journal of virology

authors： Veijola J,Pettersson RF

更新日期：1999-07-01 00:00:00

abstract：:The role of cellular genes in West Nile virus (WNV) replication is not well understood. Examination of cellular transcripts upregulated during WNV infection revealed an increase in the expression of the src family kinase (SFK) c-Yes. WNV-infected cell lines treated with the SFK inhibitor PP2 demonstrated a 2- to 4-log...

journal_title：Journal of virology

authors： Hirsch AJ,Medigeshi GR,Meyers HL,DeFilippis V,Früh K,Briese T,Lipkin WI,Nelson JA

更新日期：2005-09-01 00:00:00

abstract：:Reduction of major histocompatibility complex class I cell surface expression occurs in adenovirus-, herpes simplex virus-, human cytomegalovirus (HCMV)-, and murine cytomegalovirus-infected cell systems. Recently, it was demonstrated that the down-regulation mediated by HCMV infection is posttranslational, as a resul...

journal_title：Journal of virology

authors： Jones TR,Hanson LK,Sun L,Slater JS,Stenberg RM,Campbell AE

更新日期：1995-08-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) produces intense pulmonary inflammation, in part through its ability to induce chemokine synthesis in infected airway epithelial cells. RANTES (regulated upon activation, normally T-cell expressed and presumably secreted) is a CC chemokine which recruits and activates monocytes, lymph...

journal_title：Journal of virology

authors： Casola A,Garofalo RP,Haeberle H,Elliott TF,Lin R,Jamaluddin M,Brasier AR

更新日期：2001-07-01 00:00:00

abstract：:Measles virus (MeV), like all viruses of the order Mononegavirales, utilizes a complex consisting of genomic RNA, nucleoprotein, the RNA-dependent RNA polymerase, and a polymerase cofactor, the phosphoprotein (P), for transcription and replication. We previously showed that a recombinant MeV that does not express anot...

journal_title：Journal of virology

authors： Pfaller CK,Bloyet LM,Donohue RC,Huff AL,Bartemes WP,Yousaf I,Urzua E,Clavière M,Zachary M,de Masson d'Autume V,Carson S,Schieferecke AJ,Meyer AJ,Gerlier D,Cattaneo R

更新日期：2020-01-31 00:00:00

abstract：:The 5'-untranslated regions (5' UTRs) of picornavirus genomes contain an internal ribosomal entry site (IRES) that promotes the end-independent initiation of translation. Picornavirus IRESs are classified into four structurally distinct groups, each with different initiation factor requirements. Here, we identify a fi...

journal_title：Journal of virology

authors： Sweeney TR,Dhote V,Yu Y,Hellen CU

更新日期：2012-02-01 00:00:00

abstract：:Nucleotide sequences were determined for the complete M genome segments of two distinct hantavirus genetic lineages which were detected in hantavirus antibody- and PCR-positive white-footed mice (Peromyscus leucopus) from Indiana and Oklahoma. Phylogenetic analyses indicated that although divergent from each other, th...

journal_title：Journal of virology

authors： Morzunov SP,Rowe JE,Ksiazek TG,Peters CJ,St Jeor SC,Nichol ST

更新日期：1998-01-01 00:00:00

abstract：:We have previously shown that alpha/beta interferon (IFN-alpha/beta) and IFN-gamma inhibit hepatitis B virus (HBV) replication noncytopathically in the livers of HBV transgenic mice and in hepatocyte cell lines derived from these mice. The present study was designed to identify transcriptionally controlled hepatocellu...

journal_title：Journal of virology

authors： Wieland SF,Vega RG,Müller R,Evans CF,Hilbush B,Guidotti LG,Sutcliffe JG,Schultz PG,Chisari FV

更新日期：2003-01-01 00:00:00

abstract：:We generated Chinese hamster ovary cell lines that stably express wild-type, secreted, and glycosylphosphatidylinositol (GPI)-anchored envelope glycoprotein of human immunodeficiency virus type 1 (HIV-1). The cells expressing wild-type Env (WT cells) express both the precursor gp160 and the mature gp120/gp41 and readi...

journal_title：Journal of virology

authors： Weiss CD,White JM

更新日期：1993-12-01 00:00:00

abstract：:A distinctive feature of chronic human immunodeficiency virus type 1 (HIV-1) infection is the presence of multiple coexisting genetic variants, or subpopulations, that comprise the HIV-1 population detected in the peripheral blood. Analysis of HIV-1 RNA decay dynamics during the initiation of highly active antiretrovi...

journal_title：Journal of virology

authors： Ince WL,Harrington PR,Schnell GL,Patel-Chhabra M,Burch CL,Menezes P,Price RW,Eron JJ Jr,Swanstrom RI

更新日期：2009-05-01 00:00:00

abstract：:The replication of porcine endogenous retrovirus subgroup A (PERV-A) and PERV-B in certain human cell lines indicates that PERV may pose an infectious risk in clinical xenotransplantation. We have previously reported that human-tropic PERVs isolated from infected human cells following cocultivation with miniature swin...

journal_title：Journal of virology

authors： Wood JC,Quinn G,Suling KM,Oldmixon BA,Van Tine BA,Cina R,Arn S,Huang CA,Scobie L,Onions DE,Sachs DH,Schuurman HJ,Fishman JA,Patience C

更新日期：2004-03-01 00:00:00

abstract：:Venezuelan equine encephalitis (VEE) virus antigenic subtypes and varieties are considered either epidemic/epizootic or enzootic. In addition to epidemiological differences between the epidemic and enzootic viruses, several in vitro and in vivo laboratory markers distinguishing the viruses have been identified, includ...

journal_title：Journal of virology

authors： Powers AM,Brault AC,Kinney RM,Weaver SC

更新日期：2000-05-01 00:00:00

abstract：UNLABELLED:Type I IFN signaling, which is initiated through activation of the alpha interferon receptor (IFNAR), regulates the expression of proteins that are crucial contributors to immune responses. Paramyxoviruses, including human metapneumovirus (HMPV), have evolved mechanisms to inhibit IFNAR signaling, but the sp...

journal_title：Journal of virology

authors： Hastings AK,Erickson JJ,Schuster JE,Boyd KL,Tollefson SJ,Johnson M,Gilchuk P,Joyce S,Williams JV

更新日期：2015-04-01 00:00:00

abstract：:The VP7 and VP4 genes of seven antigenic mutants of simian rotavirus SA11 4fM (serotype 3) selected after 39 passages in the presence of SA11 4fM hyperimmune antiserum, were sequenced. Nucleotide sequence analysis indicated the following. (i) Twice as many amino acid substitutions occurred in the VP7 protein than in V...

journal_title：Journal of virology

authors： Gorziglia M,Larralde G,Ward RL

更新日期：1990-09-01 00:00:00

abstract：:The mechanisms involved in the emergence of virulent mammalian viruses were investigated in the adult immunodeficient SCID mouse infected by the attenuated prototype strain of the parvovirus Minute Virus of Mice (MVMp). Cloned MVMp intravenously inoculated in mice consistently evolved during weeks of subclinical infec...

journal_title：Journal of virology

authors： Rubio MP,López-Bueno A,Almendral JM

更新日期：2005-09-01 00:00:00

abstract：:The DA strain of Theiler's virus, a murine picornavirus, causes a persistent infection of glial cells of the white matter of the spinal cord, associated with chronic inflammation and primary demyelination. The GDVII strain causes an acute fatal grey matter encephalomyelitis. We characterized the target cells of GDVII ...

journal_title：Journal of virology

authors： Aubert C,Brahic M

更新日期：1995-05-01 00:00:00

abstract：:Simian virus 40 tumor (T) antigen, an established viral oncoprotein, causes alterations in cell growth control through interacting with, and altering the function of, cellular proteins. To examine the effects of T antigen on cell growth control, and to identify the cellular proteins with which it may functionally inte...

journal_title：Journal of virology

authors： Nacht M,Reed SI,Alwine JC

更新日期：1995-02-01 00:00:00

abstract：:The VP6 protein of bluetongue virus possesses a number of activities, including nucleoside triphosphatase, RNA binding, and helicase activity (N. Stauber, J. Martinez-Costas, G. Sutton, K. Monastyrskaya, and P. Roy, J. Virol. 71:7220-7226, 1997). Although the enzymatic functions of the protein have been documented, a ...

journal_title：Journal of virology

authors： Kar AK,Roy P

更新日期：2003-11-01 00:00:00

abstract：:The human cytomegalovirus (HCMV) UL138 protein downregulates the cell surface expression of the multidrug resistance-associated protein 1 (MRP1) transporter. We examined the genetic requirements within UL138 for MRP1 downregulation. We determined that the acidic cluster dileucine motif is essential for UL138-mediated ...

journal_title：Journal of virology

authors： Gelbmann CB,Kalejta RF

更新日期：2019-05-15 00:00:00

abstract：:The matrix (M) protein of vesicular stomatitis virus (VSV) is a potent inhibitor in vivo of transcription by all three host RNA polymerases (RNAP). In the case of host RNA polymerase II (RNAPII), the inhibition is due to lack of activity of the TATA-binding protein (TBP), which is a subunit of the basal transcription ...

journal_title：Journal of virology

authors： Yuan H,Puckett S,Lyles DS

更新日期：2001-05-01 00:00:00

abstract：:The polyomavirus proteins VP1, VP2, and VP3 move from their cytoplasmic site of synthesis into the nucleus, where virus assembly occurs. To identify cellular or viral components which might control this process, we determined the distribution of VP1, VP2, and VP3 in a soluble fraction, a cytoplasmic cytoskeleton fract...

journal_title：Journal of virology

authors： Stamatos NM,Chakrabarti S,Moss B,Hare JD

更新日期：1987-02-01 00:00:00

abstract：:The sequence relations between Kirsten murine sarcoma virus (Ki-SV), Harvey murine sarcoma virus (Ha-SV), and a rat endogenous 30S RNA were studied by electron microscope heteroduplex analysis. The sequence relationships between the sarcoma viruses and their respective parental murine leukemia viruses (Kirsten and Mol...

journal_title：Journal of virology

authors： Chien UH,Lai M,Shih TY,Verma IM,Scolnick EM,Roy-Burman P,Davidson N

更新日期：1979-09-01 00:00:00

abstract：:Human metapneumovirus (hMPV), a recently described paramyxovirus, is a major etiological agent for lower respiratory tract disease in young children that can manifest with severe cough, bronchiolitis, and pneumonia. The hMPV fusion glycoprotein (F) shares conserved functional domains with other paramyxovirus F protein...

journal_title：Journal of virology

authors： Schickli JH,Kaur J,Ulbrandt N,Spaete RR,Tang RS

更新日期：2005-08-01 00:00:00

abstract：:A human endogenous retrovirus-like element (HERV), flanked by long terminal repeats of 502 and 495 nucleotides is inserted into the human pleiotrophin (PTN) gene upstream of the open reading frame. Based on its Glu-tRNA primer binding site specificity and the location within the PTN gene, we named this element HERV-E....

journal_title：Journal of virology

authors： Schulte AM,Wellstein A

更新日期：1998-07-01 00:00:00

abstract：:To study the variability of human immunodeficiency virus type 1 (HIV-1), we used immunotoxins to select for variants within a population of H9 cells persistently infected with a molecular clone of HIV-1 designated NL4-3. Chimeric immunotoxin CD4-PE40 (a chimeric fusion protein consisting of the amino-terminal two doma...

journal_title：Journal of virology

authors： Fang H,Pincus SH

更新日期：1995-01-01 00:00:00

abstract：:The nucleotide sequences of the termini of the mature pseudorabies virus genome and of the junction between these termini in concatemeric DNA were compared. To ensure conservation of unmodified 5' and 3' termini, the end fragments obtained directly (uncloned) from mature viral DNA were sequenced. The sequence obtained...

journal_title：Journal of virology

authors： Harper L,Demarchi J,Ben-Porat T

更新日期：1986-12-01 00:00:00

abstract：:The state of intracellular viral DNA in cells infected with channel catfish virus has been studied by the Hirt selective extraction procedure and by restriction endonuclease digestion. The sedimentation properties and restriction patterns of viral DNA in the Hirt supernatant fraction indicate that the majority, if not...

journal_title：Journal of virology

authors： Cebrian J,Bucchini D,Sheldrick P

更新日期：1983-05-01 00:00:00

abstract：:Chronic viruses such as herpes simplex virus 1 (HSV-1) evade the hosts' immune system by inducing the exhaustion of antiviral T cells. In the present study, we found that exhausted HSV-specific CD8+ T cells, with elevated expression of programmed death ligand-1 (PD-1) and lymphocyte activation gene-3 (LAG-3) receptors...

journal_title：Journal of virology

authors： Roy S,Coulon PG,Prakash S,Srivastava R,Geertsema R,Dhanushkodi N,Lam C,Nguyen V,Gorospe E,Nguyen AM,Salazar S,Alomari NI,Warsi WR,BenMohamed L

更新日期：2019-08-28 00:00:00