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Studies on the glutathione S-transferase of human platelets.

Abstract：

:The glutathione S-transferases of human platelets have been compared with those of erythrocytes. Although wide variations in activity were found, in individual subjects, the activity in these cell types was significantly correlated. The enzymes demonstrated similar isoelectric points and electrophoretic mobilities and it appears that the platelet enzyme is also a product of the GST3 locus. There was no correlation between platelet enzyme activity and plasma concentrations of retinol and cholesterol, but in men, the relationship between activity and carotene was significant. It is suggested that GST3 isoenzyme activity depends on vitamin A.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Rogerson KS,Mitchell D,Lawton A,Ibbotson R,Cotton W,Strange RC

doi

10.1016/0006-291x(84)90490-x

subject

Has Abstract

pub_date

1984-07-18 00:00:00

pages

407-12

issue

1

eissn

0006-291X

issn

1090-2104

pii

0006-291X(84)90490-X

journal_volume

122

pub_type

杂志文章

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