Abstract:
:Seventeen patients having a posterior uveal melanoma underwent enucleation following documentation of tumor growth. Duration of follow-up from diagnosis to enucleation ranged from 3 weeks to 30 months. The mean rate of enlargement in cubic tumor volume was 56.3 mm3/mo for eight spindle cell melanomas and 270.3 mm3/mo for nine mixed cell melanomas. The mean tumor doubling time calculated according to the exponential growth equation was 291.6 days for the eight spindle cell melanomas and 128.2 days for the nine mixed cell melanomas. The mean mitotic activity was 3.5 mf/40 hpf for the eight spindle cell melanomas and 5.4 mf/40 hpf for the nine mixed cell melanomas. These results suggest that mixed cell posterior uveal melanomas generally grow faster and have shorter doubling times than do spindle cell melanomas.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Augsburger JJ,Gonder JR,Amsel J,Shields JA,Donoso LAdoi
10.1016/s0161-6420(84)34088-xsubject
Has Abstractpub_date
1984-12-01 00:00:00pages
1709-15issue
12eissn
0161-6420issn
1549-4713pii
S0161-6420(84)34088-Xjournal_volume
91pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract::The authors studied 11 eyes of 10 patients who complained of a recent decrease in vision and whose eyes had the clinical appearance of stage 5 retinopathy of prematurity (ROP) as diagnosed by the presence of a dense, opaque retrolenticular membrane. Patients ranged in age from 4 to 33 years, and birth weights ranged f...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32170-5
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:To assess the safety and efficacy of the Artisan/Verisyse phakic intraocular lens (IOL) for the correction of high myopia. DESIGN:Prospective, open-label, noncomparative, multicenter clinical trial. PARTICIPANTS:A total of 684 adults with axial myopia from -4.5 diopters (D) to -22 D were enrolled: 662 in th...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2007.08.039
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To evaluate relationships between the Disc Damage Likelihood Scale (DDLS), global and sectoral structural parameters provided by the Heidelberg Retina Tomograph (HRT), and global and regional functional loss in visual field (VF) testing. DESIGN:Consecutive observational case series. PARTICIPANTS:One hundred t...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.10.055
更新日期:2006-04-01 00:00:00
abstract::We performed morphologic and tissue culture studies on scleral tissues obtained from a nanophthalmic patient. Seen by light and electron microscopy, collagens in these unusually thick scleral tissues were arranged in irregularly interlacing bundles. The size of the collagen fibers was more variable than that observed ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33704-7
更新日期:1986-04-01 00:00:00
abstract:PURPOSE:To evaluate the outcomes of combined deep sclerectomy and trabeculectomy (penetrating deep sclerectomy) in pediatric glaucoma. DESIGN:Retrospective, nonconsecutive, noncomparative, interventional case series. PARTICIPANTS:Children suffering from pediatric glaucoma who underwent surgery between March 1997 and ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.08.039
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To investigate whether vascular endothelial growth factor (VEGF) or soluble intercellular adhesion molecule 1 (sICAM-1) is related to diabetic macular edema (DME). DESIGN:Retrospective case-control study. PARTICIPANTS:Thirty-three patients who had DME and 13 patients with nondiabetic ocular disease (control g...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2004.11.045
更新日期:2005-05-01 00:00:00
abstract::Eighteen healthy volunteers participated in a histamine challenge, dose response study of cimetidine (H2 antagonist)/pyrilamine (H1 antagonist) eyedrops. This was a randomized, double-masked, multiple-crossover trial, consisting of six visits spaced 48 hours apart. At each visit, subjects were pretreated with one of s...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(86)33789-8
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:Intraoperative floppy iris syndrome (IFIS) caused by systemic alpha-blockers has been associated with an increased risk of cataract surgical complications when the surgeon was unaware of the medication history and did not anticipate its occurrence. This study was undertaken to evaluate the surgical outcomes and...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2007.01.011
更新日期:2007-05-01 00:00:00
abstract::Thirteen keratophakia patients were followed for 13 to 35 months. Eighteen cases of hyperopic keratomileusis or hyperopic keratomileusis using preserved corneal tissue were followed for 2 to 30 months. All 13 patients who underwent keratophakia achieved 20/50 or better acuity. All seven patients having hyperopic kerat...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34957-4
更新日期:1981-08-01 00:00:00
abstract:OBJECTIVE:The purpose of the study was to demonstrate that the arteriovenous shunt at the arteriovenous crossing could occur in major retinal vascular diseases other than Takayasu disease. DESIGN:Clinical review of consecutive case series. PARTICIPANTS:The authors studied 1885 eyes with retinal vascular diseases such...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(98)97030-0
更新日期:1998-07-01 00:00:00
abstract:PURPOSE:To determine the intraocular pressure (IOP) profile during and after systemic dexamethasone treatment in preterm very low birth weight (VLBW; <1500 g) infants. DESIGN:A cohort study at a university-affiliated tertiary neonatal center. PARTICIPANTS:Twenty-seven VLBW infants who received a 3-week dose-tapering ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.01.010
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To describe the observed frequency of oculo-auriculo-vertebral spectrum (OAVS) in patients with dermolipoma. DESIGN:Retrospective case series. PARTICIPANTS:Patients with primary presentation of ocular dermolipoma. METHODS:All patients with ocular dermolipoma or lipodermoid were identified from the authors'...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2013.01.015
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:Ketorolac is a new, parenteral, nonsteroidal, anti-inflammatory agent. The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. METHODS:A prospective, randomized, d...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(94)31238-3
更新日期:1994-05-01 00:00:00
abstract::The distribution of fluorescein between the anterior chamber and the anterior vitreous was measured in two groups of patients after oral administration: group I, extracapsular cataract extraction (ECCE) patients with intact capsule and posterior chamber intraocular lens (PC IOL) (n = 12); group II, intracapsular catar...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Two large studies from the Armed Forces Institute of Pathology (AFIP) have listed the various lesions which may clinically resemble malignant melanomas of the posterior uvea (pseudomelanomas). The studies from the AFIP were based upon histologic examination of eyes which were enucleated. The present study reports on 4...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35201-9
更新日期:1980-06-01 00:00:00
abstract::We studied the macrostructural characteristics of papillary changes of the upper tarsal conjunctiva associated with the wearing of polymethyl methacrylate (PMMA) contact lenses. Fifty subjects with elevated conjunctival papillae greater than 0.3 mm in diameter were studied. Macrostructural characteristics recorded wer...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34899-4
更新日期:1981-11-01 00:00:00
abstract::Normal crystalline lenses and a variety of primary and secondary cataracts were photographed with a contact clinical specular microscope having a new W10X long working distance objective. In the normal lens, the anterior and posterior cell pattern and the lens fiber pattern could be seen. In patients with developing c...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(83)34548-6
更新日期:1983-04-01 00:00:00
abstract:PURPOSE:To ascertain operator learning effect, and to quantify the interoperator reproducibility, using the newly introduced GDx VCC (variable corneal compensator) scanning laser polarimeter. DESIGN:Prospective instrument validation study. PARTICIPANTS:Three operators with no prior experience in operating the GDx VCC...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2004.08.013
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:The authors describe the rare condition of an abscess within a hydroxyapatite orbital implant in two patients who had undergone seemingly uncomplicated enucleation and orbital implant surgery. METHODS:In the first patient, 14 weeks postoperatively, a chronic discharge developed and the socket became uncomforta...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(96)30427-2
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate the influence of disc neovascularization on the outcome of vitreous surgery for tractional retinal detachment (TRD) after branch retinal vein occlusion (BRVO). DESIGN:The study design was a retrospective case series. PARTICIPANTS:Twenty-two eyes of 22 patients who had undergo...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(98)93021-4
更新日期:1998-03-01 00:00:00
abstract:PURPOSE:To evaluate structural changes in the cornea and anterior chamber (AC) after LASIK for myopia. DESIGN:Retrospective nonrandomized study. PARTICIPANTS:One hundred sixty-one eyes of 83 patients (mean age, 34.5+/-8.3 years) who underwent uneventful LASIK for myopia and myopic astigmatism. The preoperative refrac...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.09.014
更新日期:2007-06-01 00:00:00
abstract::The clinical and specular microscopic results of 40 cases (39 patients) of penetrating keratoplasty during which a Kelman-style anterior chamber intraocular lens was implanted were reviewed retrospectively. Thirty-one pseudophakic eyes received an intraocular lens exchange and nine aphakic eyes received a secondary in...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32206-1
更新日期:1991-06-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of a single intravitreal injection of ocriplasmin 125 μg across relevant subpopulations of patients with symptomatic vitreomacular adhesion (VMA)/vitreomacular traction (VMT), including when associated with macular hole. DESIGN:Two multicenter, randomized, placebo-controlled, double-ma...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ophtha.2014.07.045
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:The goal of the study was to assess the affect of early surgical resection of capillary hemangiomas on the induced astigmatism of infants. DESIGN:Cohort study. PARTICIPANTS:Three infants younger than 9 months of age are included. INTERVENTION:Total resection of the astigmatism-inducing hemangiomas was perf...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(97)30178-x
更新日期:1997-07-01 00:00:00
abstract::The Amsler grid is a suprathreshold target and thus may fail to detect relative scotomas. If the grid is viewed through two cross-polarizing filters creating low luminance conditions (threshold Amsler grid testing) the test is far more sensitive. Ten patients with disorders of the macula with normal standard white Ams...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(87)33315-9
更新日期:1987-09-01 00:00:00
abstract:PURPOSE:To determine whether scleral buckle placement at the time of primary repair of open-globe injury of the posterior segment is beneficial. DESIGN:Retrospective, comparative, nonrandomized interventional study. PARTICIPANTS:One hundred twenty-five open-globe injuries treated at the Duke University Medical Center...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00212-8
更新日期:2000-10-01 00:00:00
abstract:PURPOSE:To recognize discoid lupus erythematosus (DLE) as a treatable cause of chronic blepharoconjunctivitis. DESIGN:Retrospective observational case series. PARTICIPANTS:Records of 5 patients with biopsy-proven DLE were reviewed. METHODS:Clinical and pathology records were examined. MAIN OUTCOME MEASURES:Patients...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.01.035
更新日期:2005-05-01 00:00:00
abstract::We recently studied members from a family with autosomal dominant iris coloboma. All affected members had either unilateral or bilateral iris coloboma and bilateral peripheral corneal changes indistinguishable from those seen in aniridia. The corneal changes consisted of well-demarcated pannus-like growths extending f...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33738-2
更新日期:1986-03-01 00:00:00
abstract::One hundred twelve patients with vitiligo were examined for ocular abnormalities. Discrete areas of depigmentation with associated pigment hyperplasia clinically appearing to involve the choroid and retinal pigment epithelium were observed in 44 patients, and active uveitis was seen in nine patients. The changes obser...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(79)35413-6
更新日期:1979-06-01 00:00:00
abstract:PURPOSE:Diabetic patients have a greater risk of nonarteritic anterior ischemic optic neuropathy (NAION) than nondiabetic patients. We compare visual outcomes, prevalence of bilateral/sequential ION, and predictors of visual outcomes in NAION between diabetic and nondiabetic patients. DESIGN:Case-control study. PARTI...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2016.11.029
更新日期:2017-04-01 00:00:00