Abstract:
PURPOSE:To evaluate relationships between the Disc Damage Likelihood Scale (DDLS), global and sectoral structural parameters provided by the Heidelberg Retina Tomograph (HRT), and global and regional functional loss in visual field (VF) testing. DESIGN:Consecutive observational case series. PARTICIPANTS:One hundred ten eyes from 110 patients categorized as glaucoma, glaucoma suspect, or normal. METHODS:Participants were examined clinically to grade the DDLS score and were tested with HRT and Swedish Interactive Threshold Algorithm standard 24-2 VF tests. All tests were performed within 6 months of each other by examiners masked to the other findings. For each patient, the eye with the worse mean deviation (MD) of the VF test was enrolled in the study. Each field was divided into 6 sectors based on a published scheme, and the MD for each sector was calculated. The relationships among clinical DDLS score, HRT parameters, and VF indexes were analyzed by correlation coefficients and linear regression analysis. MAIN OUTCOME MEASURES:The relationship between the DDLS score, global and sectoral optic disc (HRT) parameters, and global and sectoral VF MDs was evaluated. RESULTS:The DDLS showed significant correlation with all global and sectoral VF indexes (r = -0.39 to -0.62, all Ps < 0.0001) and with sectoral rim area HRT measurements (r = -0.27 to -0.51, all Ps < 0.006). The DDLS correlated most strongly with superior and inferior regional data from HRT and VF, and less well with temporal and nasal data. Heidelberg Retina Tomograph rim area and rim volume were the only HRT parameters to correlate moderately with global VF MD (r = 0.30, P = 0.0018, and r = 0.28, P = 0.0030, respectively). Sectoral HRT rim area correlated moderately strongly with the corresponding sectoral VF MDs in the superior and inferior sectors (r = 0.35-0.46, P = <0.0001-0.04). CONCLUSION:Clinical disc assessment and laser tomographic data that determine the state of the neuroretinal rim are associated with sensitivity loss in VF testing in corresponding regions.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Danesh-Meyer HV,Ku JY,Papchenko TL,Jayasundera T,Hsiang JC,Gamble GDdoi
10.1016/j.ophtha.2005.10.055subject
Has Abstractpub_date
2006-04-01 00:00:00pages
603-11issue
4eissn
0161-6420issn
1549-4713pii
S0161-6420(05)01441-7journal_volume
113pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract::From 1984 to 1989, 24 patients with desperate ocular surface wetting problems due to mucus deficiency syndrome with extensive symblephara or lid fusion were treated by autologous free transplants of nasal mucosa from the nasal conchae. This procedure covers the ocular surface not only with nonkeratinizing epithelium b...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(90)32471-5
更新日期:1990-08-01 00:00:00
abstract:OBJECTIVE:To report the effects of intravenous immunoglobulin treatment of ten patients with progressive ocular cicatricial pemphigoid who did not respond to conventional immunomodulatory regimens. DESIGN:Noncomparative, interventional case series. PARTICIPANTS:Ten patients with biopsy-proven progressive cicatricial ...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/S0161-6420(99)90496-7
更新日期:1999-11-01 00:00:00
abstract:PURPOSE:The purpose of this article is to demonstrate how mobilization of the orbicularis oculi muscle can improve viability, appearance, and function of free skin grafts in the periocular region. By enhancing blood supply with this technique, healing often can be achieved in difficult reconstructive cases. METHODS:Se...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(95)30995-5
更新日期:1995-03-01 00:00:00
abstract:PURPOSE:To determine whether scatter and grid laser photocoagulation (laser) adds benefit to ranibizumab injections in patients with macular edema from retinal vein occlusion (RVO) and to compare 0.5-mg with 2.0-mg ranibizumab. DESIGN:Randomized, double-masked, controlled clinical trial. PARTICIPANTS:Thirty-nine pati...
journal_title:Ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ophtha.2015.04.006
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:This study aimed to examine the characteristics of intraretinal changes associated with macular holes and epiretinal membranes by scanning retinal thickness analysis. STUDY DESIGN:The study design was a nonconsecutive case series. PATIENTS:Fifty-six eyes of patients who had either a suspected or clinically ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(98)91274-x
更新日期:1998-01-01 00:00:00
abstract::Computed tomographic scanning is an excellent modality for evaluation of most orbital and intracranial tumors and strokes. However, MR scanning is definitely superior to CT when evaluating for multiple sclerosis, posterior fossa lesions (evaluation of gaze palsies, internuclear ophthalmoplegia, and downbeat nystagmus)...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0161-6420(89)32877-6
更新日期:1989-04-01 00:00:00
abstract:PURPOSE:To evaluate the effect of systemic factors on best-corrected visual acuity (BCVA) achieved with ranibizumab (Lucentis; Genentech, Inc, South San Francisco, CA) for treatment of diabetic macular edema (DME) in the RIDE and RISE phase 3 studies. DESIGN:Exploratory, post hoc analysis of 2 randomized, double-maske...
journal_title:Ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ophtha.2016.03.038
更新日期:2016-07-01 00:00:00
abstract::Radial keratotomy was performed in 33 rabbits using an eight-incision technique. At various postoperative intervals up to 90 days, these eyes were enucleated and subjected to increasing quantitated trauma until ocular rupture occurred. Control animals (13 eyes) were subjected to similar trauma. The eyes that had surge...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(83)34502-4
更新日期:1983-06-01 00:00:00
abstract:PURPOSE:To investigate the characteristics and prognosis of immune rejection after allogeneic cultivated limbal epithelial transplantation (CLET). DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Forty-two eyes of 41 patients undergoing allogeneic CLET for total limbal stem cell deficiency who completed...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.11.001
更新日期:2013-05-01 00:00:00
abstract::Optical penalization for distance is a useful alternative to occlusion for treating amblyopia, and as maintenance therapy following occlusion. It is particularly useful in cases of patching noncompliance. The major key to patient acceptance is choosing the minimal amount of penalization necessary, while still ensuring...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)33821-6
更新日期:1985-11-01 00:00:00
abstract::This report describes a peculiar syndrome occurring as a complication of cataract extraction. The syndrome is characterized initially by (1) acute loss of central and paracentral vision discovered usually on the first postoperative day; (2) diffuse and patchy whitening of the outer retinal layers in the posterior fund...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34615-1
更新日期:1982-12-01 00:00:00
abstract::Midfacial trauma causes a variety of functional and cosmetic problems that concern many surgical specialties. Fractures of the lacrimal sac fossa and lacrimal canal and compromise of the intrinsic membranous pathways are frequently not addressed, requiring late lacrimal bypass surgery in many cases. Silicone intubatio...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(87)33466-9
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND/PURPOSE:To assess the potential of a new diagnostic technique called optical coherence tomography for imaging macular disease. Optical coherence tomography is a novel noninvasive, noncontact imaging modality which produces high depth resolution (10 microns) cross-sectional tomographs of ocular tissue. It is ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(95)31032-9
更新日期:1995-02-01 00:00:00
abstract:PURPOSE:To assess the relationship between cardiovascular disease and cardiovascular risk factors, other than smoking, and risk of long-term incident age-related macular degeneration (AMD). DESIGN:Population-based cohort study. PARTICIPANTS:There were 3654 baseline (1992-1994) participants aged > or = 49 years includ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.09.033
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To describe variations in retinal nerve fiber layer (RNFL) thickness based on spectral-domain (SD) OCT in a multiethnic Asian population. DESIGN:Population-based, cross-sectional study. PARTICIPANTS:Ethnic Chinese, Malay, and Indian adults older than 48 years without glaucoma who were recruited from the Singa...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2018.11.031
更新日期:2019-05-01 00:00:00
abstract::Intraocular lenses have been regulated by the Bureau of Devices of the Food and Drug Administration since February 9, 1978. One year ago, data were reported through August 9, 1979, at which time more than 177,000 lenses of four different classes had been implanted. In the meantime, appeals and legal action by the Publ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)35014-3
更新日期:1981-05-01 00:00:00
abstract::Enophthalmos with an associated superior sulcus syndrome is a common finding in the anophthalmic socket. Two common causes are: (1) progressive relaxation of the lower eyelid leading to downward migration of the prosthesis and associated ectropion formation; and (2) decreased volume of the orbit. Relaxation of the low...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35091-4
更新日期:1980-12-01 00:00:00
abstract:PURPOSE:To assess distribution, correlations, and prognostic effect of tumor (T), node (N), and metastasis (M) staging on relapse and survival. DESIGN:Retrospective clinical review. PARTICIPANTS:Sixty-three patients diagnosed with primary ocular adnexal lymphoma (OAL) between January 1986 and November 2011. METHODS:...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2013.02.003
更新日期:2013-09-01 00:00:00
abstract::Five patients seen in a one-year period with advanced malignant melanoma of the choroid in eyes with low visual acuity and clear media are reported. The low visual acuity appeared clinically to be antecedent to the malignant tumor; although in certain cases it may have been related to the occult melanoma, this was not...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(79)35423-9
更新日期:1979-06-01 00:00:00
abstract:PURPOSE:To determine the impact that cataract and cataract surgery have on clinical measurements of vision, reading speed, objective mobility performance, and subjective visual functioning. DESIGN:Prospective, population-based study. PARTICIPANTS:A total of 1739 Salisbury Eye Evaluation (SEE) participants without pre...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.10.009
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To determine the antibiotic susceptibility patterns of conjunctival bacterial flora isolated preoperatively from patients undergoing anterior segment surgery. DESIGN:Prospective observational study. PARTICIPANTS:One hundred fifty-six eyes from 139 patients scheduled for anterior segment surgery were enrolled ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(03)00735-8
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To determine the long-term motor and sensory results after early surgical correction of patients with congenital esotropia. DESIGN:Noncomparative interventional case series. PARTICIPANTS:Ten infants with congenital esotropia. INTERVENTION:Patients had bimedial rectus recession between 83 and 159 days of ag...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(99)90337-8
更新日期:1999-09-01 00:00:00
abstract:PURPOSE:To determine the prevalence of and factors associated with diabetic retinopathy (DR) among non-Indigenous and Indigenous Australian adults with self-reported diabetes. DESIGN:Population-based cross-sectional study. PARTICIPANTS:Non-Indigenous Australians (50-98 years of age) and Indigenous Australians (40-92 ...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2017.02.004
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of nerve growth factor (NGF) in patients with neurotrophic keratitis. DESIGN:Prospective, noncomparative, interventional case series. PARTICIPANTS:Forty-five eyes of 43 consecutive patients with moderate (stage 2, n = 17) to severe (stage 3, n = 28) neurotrophic keratitis unresponsi...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/s0161-6420(00)00163-9
更新日期:2000-07-01 00:00:00
abstract:PURPOSE:To evaluate the outcomes of combined deep sclerectomy and trabeculectomy (penetrating deep sclerectomy) in pediatric glaucoma. DESIGN:Retrospective, nonconsecutive, noncomparative, interventional case series. PARTICIPANTS:Children suffering from pediatric glaucoma who underwent surgery between March 1997 and ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.08.039
更新日期:2009-01-01 00:00:00
abstract::It is traditionally taught in ophthalmic optics that the "effective" bifocal add is greater than the prescribed add in aphakic spectacles. Because the reading segment is fabricated on the front surface of the lens, the added back vertex power is significantly greater than the prescribed add. It is taught that the effe...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32744-8
更新日期:1989-08-01 00:00:00
abstract:PURPOSE:To investigate the effect of posterior chamber intraocular lens (PC IOL) size and construction on the capsular bag in human cadaver eyes. METHODS:Studies were done at two timeframes: (1) short term (prospective)--the effect of 12 different IOLs on the capsular bag configuration after experimental implantation;...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(95)30897-4
更新日期:1995-08-01 00:00:00
abstract:OBJECTIVE:To determine whether multiple B-scan averaging improves the quality of spectral-domain optical coherence tomography (SD OCT) images of the retina. DESIGN:Prospective cross-sectional study. PARTICIPANTS:One hundred one eyes of 84 patients with various retinal diseases. METHODS:A prototype SD OCT system was ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.09.001
更新日期:2008-06-01 00:00:00
abstract::The authors examined the relationship of change in tumor height after proton beam irradiation with the risk of metastasis in 700 patients treated for uveal melanoma before July 1, 1986. Rates of change in tumor height were computed for each patient using follow-up ultrasonographic measures during the first 2 years aft...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32685-6
更新日期:1989-10-01 00:00:00
abstract:PURPOSE:To characterize the phenotype and investigate the associations of intraretinal crystalline deposits in a large cohort with type 2 idiopathic macular telangiectasia (MacTel). DESIGN:Case-control study. PARTICIPANTS:Patients with and without retinal crystals from the Macular Telangiectasia Project, an internati...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2011.05.022
更新日期:2011-12-01 00:00:00