Characterization of ndh gene of isoniazid resistant and susceptible Mycobacterium tuberculosis isolates from Brazil.

abstract：:In many helminth infected hosts the number of eosinophils increases dramatically, often without any concurrent increases in the number of other leukocytes, so that eosinophils become the dominant cell type. Many experimental investigations have shown that the eosinophilia is induced by interleukin-5 (IL-5) but its fun...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ovington KS,Behm CA

更新日期：1997-01-01 00:00:00

abstract：:Small molecular weight compounds from Mandevilla velutina and from Eclipta prostata were found to be active against snakebite. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mors WB

更新日期：1991-01-01 00:00:00

abstract：:The high level of protection elicited in rodents and primates by the radiation-attenuated schistosome vaccine gives hope that a human vaccine relying on equivalent mechanisms is feasible. In humans, a vaccine would be undoubtedly administered to previously or currently infected individuals. We have therefore used the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Coulson PS,Kariuki TM

更新日期：2006-09-01 00:00:00

abstract：:The present report describes an alternative method for in vitro detection of HIV-1-specific antibody secretion in 24h of culture employing as stimulant of peripheral blood mononuclear cells the disrupted inactivated whole virus adsorbed onto microwells in a commercial ELISA kit plates. The results obtained from this t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Caterino-de-Araujo A

更新日期：1992-04-01 00:00:00

abstract：:Toxocara cati is a common feline parasite transmitted by the ingestion of embryonated eggs, by the transmammary route or by predation of paratenic hosts harbouring third-stage larvae in their bodies. In the present study, the larval distribution of T. cati in tissues and organs of Rattus norvegicus experimentally infe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos SV,Lescano SZ,Castro JM,Chieffi PP

更新日期：2009-09-01 00:00:00

abstract：:Triatoma brasiliensis is composed of at least four geographic populations (brasiliensis, melanica, macromelasoma, and juazeiro) that have distinct chromatic, morphologic, biologic and ecologic patterns, and genetic composition. Reciprocal crosses between all pairwise combinations were carried out in order to evaluate ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Costa J,Almeida CE,Dujardin JP,Beard CB

更新日期：2003-07-01 00:00:00

abstract：:A longitudinal study was conducted in Manaus, Brazil, to monitor changes of adult Aedes aegypti (L.) abundance. The objectives were to compare mosquito collections of two trap types, to characterise temporal changes of the mosquito population, to investigate the influence of meteorological variables on mosquito collec...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Degener CM,Ázara TM,Roque RA,Codeço CT,Nobre AA,Ohly JJ,Geier M,Eiras ÁE

更新日期：2014-12-01 00:00:00

abstract：:An unusually high incidence of microcephaly in newborns has recently been observed in Brazil. There is a temporal association between the increase in cases of microcephaly and the Zika virus (ZIKV) epidemic. Viral RNA has been detected in amniotic fluid samples, placental tissues and newborn and fetal brain tissues. H...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Noronha Ld,Zanluca C,Azevedo ML,Luz KG,Santos CN

更新日期：2016-05-01 00:00:00

abstract：:There is a general consensus that during chronic Trypanosoma cruzi infection, the host immune system induces complex processes to ensure the control of parasite growth while preserving the potential to mount and maintain a life-long controlled humoral and cellular immune response against the invading pathogen. This re...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sathler-Avelar R,Vitelli-Avelar DM,Teixeira-Carvalho A,Martins-Filho OA

更新日期：2009-07-01 00:00:00

abstract：:This paper presents epidemiological, laboratory, and clinical data on 12 years of dengue virus activity in the State of Rio de Janeiro from the time the disease was first confirmed virologically in April 1986 through April 1998. DEN-1 and DEN-2 viruses are the serotypes circulating in the state and were responsible fo...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nogueira RM,Miagostovich MP,Schatzmayr HG,dos Santos FB,de Araújo ES,de Filippis AM,de Souza RV,Zagne SM,Nicolai C,Baran M,Teixeira Filho G

更新日期：1999-05-01 00:00:00

abstract：:[This corrects the article doi: 10.1590/0074-02760180073]. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors：

更新日期：2018-01-01 00:00:00

abstract：:Diphyllobothriasis is an infection of the small intestine by the broad tapeworm Diphyllobothrium sp. The associated symptomatology is nonspecific, but megaloblastic anemia is a well-described complication. Although the infection is common in temperate regions, descriptions in South America have so far been limited to ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos FL,de Faro LB

更新日期：2005-10-01 00:00:00

abstract：:The population biology of three populations of Panstrongylus megistus was compared to determine possible influence on the behaviour and epidemiological importance of this species. The results demonstrated differences in terms of egg eclosion time, nymphal mortality and development rates, and feeding and defaecation ra...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barbosa SE,Soares RP,Pires HH,Diotaiuti L

更新日期：2001-08-01 00:00:00

abstract：:Triatoma nitida was found in 14 (0.4%) out of 3,726 houses located in six departments across Guatemala, which were surveyed from 1994 to 1998 by the man-hour collection method. Compared to previous information, the distribution of T. nitida in Guatemala has increased from five to nine departments; the species is prese...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Monroy C,Bustamante DM,Rodas A,Rosales R,Mejía M,Tabaru Y

更新日期：2003-01-01 00:00:00

abstract：:Schistosoma mansoni is one of the three main causative agents of human schistosomiasis, a major health problem with a vast socio-economic impact. Recent advances in the proteomic analysis of schistosomes have revealed that peptidases are the main virulence factors involved in the pathogenesis of this disease. In this ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva LL,Marcet-Houben M,Zerlotini A,Gabaldón T,Oliveira G,Nahum LA

更新日期：2011-11-01 00:00:00

abstract：:This study objective was to evaluate the cytokines associated with early events of hepatic fibrosis in schistosomiasis mansoni. Hepatic fibrosis was classified by ultrasonography in 94 patients. Immunological evaluation was performed by measurement of secreted cytokines (interleukin IL-5, IL-10, IL-13, interferon-gamm...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Magalhães A,Miranda DG,Miranda RG,Araújo MI,Jesus AA,Silva A,Santana LB,Pearce E,Carvalho EM,Jesus AR

更新日期：2004-01-01 00:00:00

abstract：:The mechanisms that facilitate the adaptation of Trypanosoma cruzi to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that resulted from integ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Zacks MA

更新日期：2007-02-01 00:00:00

abstract：:Mitochondrial DNA of Biomphalaria tenagophila, a mollusc intermediate host of Schistosoma mansoni in Brazil, was sequenced and characterised. The genome size found for B. tenagophila was 13,722 bp and contained 13 messenger RNAs, 22 transfer RNAs (tRNA) and two ribosomal RNAs (rRNA). In addition to sequencing, the mit...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Jannotti-Passos LK,Ruiz JC,Caldeira RL,Murta SM,Coelho PM,Carvalho OS

更新日期：2010-07-01 00:00:00

abstract：:Cytidine deaminase (MtCDA), encoded by cdd gene (Rv3315c), is the only enzyme identified in nucleotide biosynthesis pathway of Mycobacterium tuberculosis that is able to recycle cytidine and deoxycytidine. An M. tuberculosis knockout strain for cdd gene was obtained by allelic replacement. Evaluation of mRNA expressio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Villela AD,Rodrigues-Junior VS,Pinto AFM,Falcão VCA,Sánchez-Quitian ZA,Eichler P,Bizarro CV,Basso LA,Santos DS

更新日期：2017-11-01 00:00:00

abstract：:Qualitative bacteriological analysis was carried out in two sewage treatment plants in the city of Rio de Janeiro during the period 1984-1985. Specific points of the plants were selected for the collection of affluent and effluent samples. The study involved the isolation and the identification of 540 cultures of Esch...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ribeiro Dias JC,Vicente AC,Hofer E

更新日期：1987-07-01 00:00:00

abstract：:The chromatin of Trypanosoma congolense was analyzed by electron microscopy. The chromatin is organized as nucleosome filaments but does not form a 30 nm fiber. There are five groups of histones, including a histone H1-like protein, which as a molecular weight within the range of the core histones, and is extremely hy...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Schlimme W,Burri M,Betschart B,Hecker H

更新日期：1994-04-01 00:00:00

abstract：:The enzyme-linked immunosorbent assay (Elisa) was used to examine sera of 104 children and adults in Jos, Plateau State, Nigeria for anti-toxocaral antibodies, out of which 31 (29.8%) were reactive. The seropositive rates were 30.4% for adults, 29.6% for children, 34% for females and 25.9% for males. However, the diff...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ajayi OO,Duhlinska DD,Agwale SM,Njoku M

更新日期：2000-03-01 00:00:00

abstract：:A new species of Brazilian phlebotomine sandfly found in Brazil, municipality of Diamantina, state of Minas Gerais, is described based on males and females collected in a quartzite cave. The body of spermathecae is continuous to the individual duct, lanky and tapering at the end, with conical shaped, not striated and ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barata RA,Serra e Meira PC,Carvalho GM

更新日期：2012-12-01 00:00:00

abstract：:This article presents an overview of the currently available drugs nifurtimox (NFX) and benznidazole (BZN) used against Trypanosoma cruzi, the aetiological agent of Chagas disease; herein we discuss their limitations along with potential alternatives with a focus on ergosterol biosynthesis inhibitors (EBI). These comp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Urbina JA

更新日期：2009-07-01 00:00:00

abstract：:Patients with acute schistosomiasis were studied before and after oxamniquine treatment. They had been exposed to cercariae 5 to 9 weeks before, and presented compatible clinical manifestations, eosinophilia, and high levels of total IgE. Interferon-gamma (IFN-gamma) and interleukin-4 were measured by ELISA in whole b...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Souza JR,Morais CN,Aroucha ML,Miranda PJ,Barbosa CS,Domingues AL,Carvalho Júnior LB,Abath FG,Montenegro SM

更新日期：2007-05-01 00:00:00

abstract：:A survey of the carrion fauna was made at two sites in Curitiba, State of Paraná, with the objective of describing the insects associated with carrion and setting up a preliminary data-base for medico-legal purposes in south Brazil. Vertebrate exclusion experiments were carried out in each season between 1994 and 1995...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Moura MO,de Carvalho CJ,Monteiro-Filho EL

更新日期：1997-03-01 00:00:00

abstract：:Leptospirosis is a zoonotic disease caused by pathogenic spirochetes of the Leptospira genus. Vaccination with bacterins has severe limitations. Here, we evaluated the N-terminal region of the leptospiral immunoglobulin-like B protein (LigBrep) as a vaccine candidate against leptospirosis using immunisation strategies...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Forster KM,Hartwig DD,Oliveira TL,Bacelo KL,Schuch R,Amaral MG,Dellagostin OA

更新日期：2015-12-01 00:00:00

abstract：:To compare the epidemiological profile and socioeconomic factors associated to the infection by Schistosoma mansoni in a rural and an urban endemic area a cross-sectional study was performed in Agua Branca de Minas (rural area) and Bela Fama (urban area), both situated in the State of Minas Gerais, Brazil. Two hundred...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Amorim MN,Rabello A,Contreras RL,Katz N

更新日期：1997-09-01 00:00:00

abstract：:Sand flies were collected in the central region of the state of Rondônia (W 64 degrees 30' to 63 degrees 00' and S 10 degrees 00'to 11 degrees 00') using Shannon and CDC light traps from October 1997 to August 2000. A total of 85,850 specimens representing 78 named species were captured. Of these 14 were new records f...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gil LH,Basano SA,Souza AA,Silva MG,Barata I,Ishikawa EA,Camargo LM,Shaw JJ

更新日期：2003-09-01 00:00:00

abstract：:We investigated the cytokine profile of peripheral mononuclear cells from chronic osteomyelitis (OST) patients following in vitro stimulation with staphylococcal enterotoxin A (SEA). We demonstrate that stimulation with SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-α, i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira GF,Moraes C,Silveira AM,Correa-Oliveira R,Teixeira-Carvalho A,Martins-Filho OA,Moreno EC,do Carmo LS,Fraga LA,Malaquias LC

更新日期：2012-05-01 00:00:00