Role of aluminum in dialysis dementia.

Abstract:

:Between September 1972 and January 1976 an outbreak of dialysis dementia affected 20 patients maintained by long-term hemodialysis. The clinical picture was characterized by an insidious onset of altered behaviour, dementia, speech disturbance, myoclonus, and convulsions. Nineteen patients died, but one patient has survived for 16 months. It was later established that in June 1972 the city had altered its method of water purification and that this resulted in higher water aluminum levels. The temporal relation between periods of high water-aluminum content and the appearance of new cases supports the view that aluminum may play a role in the causation of dialysis dementia.

journal_name

Ann Intern Med

authors

Dunea G,Mahurkar SD,Mamdani B,Smith EC

doi

10.7326/0003-4819-88-4-502

subject

Has Abstract

pub_date

1978-04-01 00:00:00

pages

502-4

issue

4

eissn

0003-4819

issn

1539-3704

journal_volume

88

pub_type

杂志文章
  • Prospective study of color duplex ultrasonography compared with contrast venography in patients suspected of having deep venous thrombosis of the upper extremities.

    abstract:BACKGROUND:The optimal strategy for diagnosis of deep venous thrombosis (DVT) is less well established for the upper extremities than for the lower extremities. Duplex color ultrasonography can be difficult to perform in the upper extremities because of their anatomy, and contrast venography is often indicated. Moreove...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-136-12-200206180-00007

    authors: Baarslag HJ,van Beek EJ,Koopman MM,Reekers JA

    更新日期:2002-06-18 00:00:00

  • Qui tam: suing physicians who make false claims.

    abstract::The 1986 False Claims Act Amendments authorize private citizens to sue on behalf of the U.S. government to recover federal funds from fraudulent recipients. The "relator" receives a share of any proceeds from a successful lawsuit. Originally enacted because of defense procurement scandals, this statute also applies to...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-114-12-1050

    authors: Hsia DC

    更新日期:1991-06-15 00:00:00

  • Routine vitamin supplementation to prevent cardiovascular disease: a summary of the evidence for the U.S. Preventive Services Task Force.

    abstract:BACKGROUND:Antioxidant vitamins are thought to play a role in atherosclerosis. Supplementation of these nutrients has been explored as a means of reducing cardiovascular morbidity and mortality. PURPOSE:To assess the evidence of the effectiveness of vitamin supplementation, specifically vitamins A, C, and E; beta-caro...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-139-1-200307010-00014

    authors: Morris CD,Carson S

    更新日期:2003-07-01 00:00:00

  • Clinical competence in internal medicine.

    abstract::To describe more explicitly the components of competence required of the internist, The American Board of Internal Medicine has analyzed the medical encounter and defined the major variables involved: the abilities required of the internist, the tasks that must be performed to solve a medical problem, the medical illn...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-90-3-402

    authors:

    更新日期:1979-03-01 00:00:00

  • Serial impedance plethysmography in pregnant patients with clinically suspected deep-vein thrombosis. Clinical validity of negative findings.

    abstract:STUDY OBJECTIVE:To determine the safety of withholding anticoagulant therapy in pregnant patients with clinically suspected deep-vein thrombosis who have negative results by serial impedance plethysmography. DESIGN:Prospective study evaluating prognosis by long-term follow-up to 3 months postpartum in all patients. S...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-112-9-663

    authors: Hull RD,Raskob GE,Carter CJ

    更新日期:1990-05-01 00:00:00

  • Deficiency of fat-soluble vitamins in treated patients with pancreatic insufficiency.

    abstract::Deficiency of fat-soluble vitamins (A,D,E, and K) was evaluated in 15 patients with exocrine pancreatic insufficiency secondary to chronic alcoholic pancreatitis. Mild to moderate steatorrhea was present in all patients despite oral pancreatic enzyme therapy for 27 +/- 4 months (mean +/- SE). Deficiency of a single fa...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-97-4-549

    authors: Dutta SK,Bustin MP,Russell RM,Costa BS

    更新日期:1982-10-01 00:00:00

  • Residency training in internal medicine: time for a change?

    abstract::Internal medicine residencies risk becoming obsolete if they are not adjusted to changing patterns of medical practice. Declining length of hospital stay, increased intensity of hospital care, movement of critical management decisions to outpatient settings, increased proportions of admissions for specific diagnostic ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-104-4-554

    authors: Schroeder SA,Showstack JA,Gerbert B

    更新日期:1986-04-01 00:00:00

  • The common hyperlipoproteinemias: an understanding of disease mechanisms and their control.

    abstract::Our review focuses on low density lipoprotein (LD lipoprotein) and very low density lipoprotein (VLD lipoprotein) in their roles as transporters of cholesterol and triglyceride and as factors contributing to premature arteriovascular disease. We describe the clinical manifestations of the common, primary hyperlipoprot...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-85-4-497

    authors: Fisher WR,Truitt DH

    更新日期:1976-10-01 00:00:00

  • Respiratory tract symptoms as a clue to giant cell arteritis.

    abstract::Although many manifestations of giant cell arteries are increasingly recognized, little attention has been paid to respiratory symptoms associated with this disorder. We report the cases of 16 patients with giant cell arteritis who had prominent symptoms related to the respiratory tract including cough, sore throat, a...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-101-5-594

    authors: Larson TS,Hall S,Hepper NG,Hunder GG

    更新日期:1984-11-01 00:00:00

  • Amantadine effect on peripheral airways abnormalities in influenza. A study in 15 students with natural influenza A infection.

    abstract::Amantadine HCl administration has resulted in accelerated resolution of influenza A illness. Prolonged abnormalities in pulmonary function have been described in uncomplicated influenza A. To study the effect of amantadine on these changes, we evaluated young adults with documented natural influenza A with clear chest...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-85-2-177

    authors: Little JW,Hall WJ,Douglas RG Jr,Hyde RW,Speers DM

    更新日期:1976-08-01 00:00:00

  • Screening for abdominal aortic aneurysm: U.S. Preventive Services Task Force recommendation statement.

    abstract:DESCRIPTION:Update of the 2005 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for abdominal aortic aneurysm (AAA). METHODS:The USPSTF commissioned a systematic review that assessed the evidence on the benefits and harms of screening for AAA and strategies for managing small (3.0 to 5.4 cm) sc...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,实务指引

    doi:10.7326/M14-1204

    authors: LeFevre ML,U.S. Preventive Services Task Force.

    更新日期:2014-08-19 00:00:00

  • Very low calorie diets: their efficacy, safety, and future.

    abstract::Very low calorie diets used to treat moderate and severe obesity produce average weight losses of 20 kg in 12 weeks. This paper reviews the development of very low calorie diets from research on fasting in the late 1950s and examines data on the amount of dietary protein needed to achieve positive nitrogen balance. Th...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-99-5-675

    authors: Wadden TA,Stunkard AJ,Brownell KD

    更新日期:1983-11-01 00:00:00

  • Hypophosphatemic osteomalacia: association with prostatic carcinoma.

    abstract::Hypophosphatemic osteomalacia that remits after resection of a coexisting tumor has been described in 35 patients. Because the associated neoplasms have been of mesenchymal origin, it has been inferred that this tumor-induced osteomalacia syndrome is uniquely related to tumours of this derivation. However, in the pres...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-93-2-275

    authors: Lyles KW,Berry WR,Haussler M,Harrelson JM,Drezner MK

    更新日期:1980-08-01 00:00:00

  • Marrow transplantation for the treatment of chronic myelogenous leukemia.

    abstract::One hundred ninety-eight patients with chronic myelogenous leukemia received marrow transplants after intensive chemotherapy and total body irradiation. Multivariate analysis showed disease status at time of transplantation to be the most powerful predictor of survival. The probability of long-term survival for alloge...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-104-2-155

    authors: Thomas ED,Clift RA,Fefer A,Appelbaum FR,Beatty P,Bensinger WI,Buckner CD,Cheever MA,Deeg HJ,Doney K

    更新日期:1986-02-01 00:00:00

  • Incompetent patients with limited care in the absence of family consent. A study of socioeconomic and clinical variables.

    abstract::To understand the factors that distinguish terminally ill, incompetent patients who are given do-not-resuscitate status by physicians against the wishes of the patient's family, I reviewed the charts of 20 such patients (cases) seen in consultation by the ethics committee at the Massachusetts General Hospital over 10 ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-109-10-819

    authors: Brennan TA

    更新日期:1988-11-15 00:00:00

  • Poxvirus Vectored Cytomegalovirus Vaccine to Prevent Cytomegalovirus Viremia in Transplant Recipients: A Phase 2, Randomized Clinical Trial.

    abstract:Background:Triplex vaccine was developed to enhance cytomegalovirus (CMV)-specific T cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT). Objective:To determine the safety and efficacy of Triplex. Design:First-in-patient, phase 2 trial. (ClinicalTrials.gov: NCT02506933). Setting:3...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.7326/M19-2511

    authors: Aldoss I,La Rosa C,Baden LR,Longmate J,Ariza-Heredia EJ,Rida WN,Lingaraju CR,Zhou Q,Martinez J,Kaltcheva T,Dagis A,Hardwick N,Issa NC,Farol L,Nademanee A,Al Malki MM,Forman S,Nakamura R,Diamond DJ,TRIPLEX VACCINE St

    更新日期:2020-03-03 00:00:00

  • Firearm Acquisition Without Background Checks: Results of a National Survey.

    abstract:Background:In 1994, 40% of U.S. gun owners who had recently acquired a firearm did so without a background check. No contemporary estimates exist. Objective:To estimate the proportion of current U.S. gun owners who acquired their most recent firearm without a background check, by time since and manner of acquisition, ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M16-1590

    authors: Miller M,Hepburn L,Azrael D

    更新日期:2017-02-21 00:00:00

  • Right-sided endocarditis in intravenous drug users. Prognostic features in 102 episodes.

    abstract:OBJECTIVE:To describe the clinical, laboratory, and echocardiographic findings in a large group of patients with right-sided endocarditis and to determine whether any of these findings is predictive of prognosis. DESIGN:Retrospective survey of medical records to evaluate the course of hospitalization with follow-up on...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-117-7-560

    authors: Hecht SR,Berger M

    更新日期:1992-10-01 00:00:00

  • What's in placebos: who knows? Analysis of randomized, controlled trials.

    abstract:BACKGROUND:No regulations govern placebo composition. The composition of placebos can influence trial outcomes and merits reporting. PURPOSE:To assess how often investigators specify the composition of placebos in randomized, placebo-controlled trials. DATA SOURCES:4 English-language general and internal medicine jou...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-153-8-201010190-00010

    authors: Golomb BA,Erickson LC,Koperski S,Sack D,Enkin M,Howick J

    更新日期:2010-10-19 00:00:00

  • Cardiovascular disease and mortality in older adults with small abdominal aortic aneurysms detected by ultrasonography: the cardiovascular health study.

    abstract:BACKGROUND:Persons with abdominal aortic aneurysm are more likely to have a higher prevalence of risk factors for and clinical manifestations of cardiovascular disease. It is unknown whether these factors explain the high mortality rate associated with abdominal aortic aneurysm. OBJECTIVE:To describe the risk for mort...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-134-3-200102060-00008

    authors: Newman AB,Arnold AM,Burke GL,O'Leary DH,Manolio TA

    更新日期:2001-02-06 00:00:00

  • In type 2 diabetes, some glucose-lowering drugs reduce HbA1c more than others; drugs do not differ for mortality.

    abstract:SOURCE CITATION:Tsapas A, Avgerinos I, Karagiannis T, et al. Comparative effectiveness of glucose-lowering drugs for type 2 diabetes: a systematic review and network meta-analysis. Ann Intern Med. 2020;173:278-86. 32598218. ...

    journal_title:Annals of internal medicine

    pub_type: 评论,杂志文章

    doi:10.7326/ACPJ202011170-053

    authors: Gandhi GY

    更新日期:2020-11-17 00:00:00

  • Association of fibrinogen with glycemic control and albumin excretion rate in patients with non-insulin-dependent diabetes mellitus.

    abstract:BACKGROUND:The high prevalence of classic cardiac risk factors in patients with non-insulin-dependent diabetes mellitus does not explain the increased cardiovascular-related morbidity and mortality in these patients. Fibrinogen may have a role in this excess risk. OBJECTIVE:To evaluate the following in patients with n...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-125-8-199610150-00005

    authors: Bruno G,Cavallo-Perin P,Bargero G,Borra M,D'Errico N,Pagano G

    更新日期:1996-10-15 00:00:00

  • Indications for arterial blood gas analysis.

    abstract::Arterial blood gas analysis is used to evaluate oxygen and carbon dioxide gas exchange and acid-base status. Few studies identify indications for arterial blood gas analysis, especially with regard to optimizing the quality of patient care. General indications in severely ill adults usually include pathophysiologic ab...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-105-3-390

    authors: Raffin TA

    更新日期:1986-09-01 00:00:00

  • Optimal Timing of Antiretroviral Therapy Initiation for HIV-Infected Adults With Newly Diagnosed Pulmonary Tuberculosis: A Systematic Review and Meta-analysis.

    abstract:BACKGROUND:Initiation of antiretroviral therapy (ART) during tuberculosis (TB) treatment remains challenging. PURPOSE:To assess evidence from randomized, controlled trials of the timing of ART initiation in HIV-infected adults with newly diagnosed pulmonary TB. DATA SOURCES:PubMed, EMBASE, Cochrane Central Register o...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.7326/M14-2979

    authors: Uthman OA,Okwundu C,Gbenga K,Volmink J,Dowdy D,Zumla A,Nachega JB

    更新日期:2015-07-07 00:00:00

  • Characterization of the glomerular antibody in acute poststreptococcal glomerulonephritis.

    abstract::Glomerular-fixed antibody was eluted from the kidney of a 17-year-old patient who died 2 weeks after the onset of acute poststreptococcal glomerulonephritis. Elevated titers of antibodies to streptococcal enzymes were found in the serum but not in the glomerular eluate. Streptococcal M protein and anti-M protein react...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-92-4-478

    authors: Rodríguez-Iturbe B,Rabideau D,García R,Rubio L,McIntosh RM

    更新日期:1980-04-01 00:00:00

  • Secretin-stimulated serum gastrin levels in hyperparathyroid patients from families with multiple endocrine adenomatosis type I.

    abstract::Twenty-three patients with hyperparathyroidism from six families with the multiple endocrine adenomatosis (MEA) I-syndrome were tested by secretin provocation. In nine cases this led to increases in serum gastrin ranging from 298 to 13 300 pg/ml, whereas the maximum rise in gastrin in the other 14 patients was 32 pg/m...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-86-6-719

    authors: Lamers CB,Buis JT,van Tongeren J

    更新日期:1977-06-01 00:00:00

  • Diagnostic utility of ultrasonography of leg veins in patients suspected of having pulmonary embolism.

    abstract:BACKGROUND:The standard diagnostic approach in patients suspected of having pulmonary embolism starts with perfusion-ventilation lung scanning. If the resulting scan is not diagnostic, pulmonary angiography should be done. The use of tests for deep venous thrombosis has been advocated as an adjunct to establishing the ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-126-10-199705150-00005

    authors: Turkstra F,Kuijer PM,van Beek EJ,Brandjes DP,ten Cate JW,Büller HR

    更新日期:1997-05-15 00:00:00

  • Genotyping for Human Papillomavirus Types 16 and 18 in Women With Minor Cervical Lesions: A Systematic Review and Meta-analysis.

    abstract:Background:High-risk human papillomavirus (hrHPV) testing to triage women with minor cervical lesions generates many referrals. Purpose:To evaluate the accuracy of genotyping for HPV types 16 and 18 and its utility as a second triage step after hrHPV testing in women with minor cervical lesions. Data Sources:Searches...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.7326/M15-2735

    authors: Arbyn M,Xu L,Verdoodt F,Cuzick J,Szarewski A,Belinson JL,Wentzensen N,Gage JC,Khan MJ

    更新日期:2017-01-17 00:00:00

  • Aging-related cataract: laboratory investigation and clinical management.

    abstract::Cataract disrupts the crystalline lens, a transparent, elastic, avascular, biconvex structure composed of a capsule, lens epithelium, and lens fiber cells. Many factors contribute to the progression of lens opacity, but aging is most frequently associated with cataract. As aging-related cataract develops, many biochem...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-102-1-82

    authors: Straatsma BR,Foos RY,Horwitz J,Gardner KM,Pettit TH

    更新日期:1985-01-01 00:00:00

  • Lymphadenopathy-associated virus: from molecular biology to pathogenicity.

    abstract::Recent data indicate that the lymphadenopathy-associated virus (LAV) is morphologically similar to animal lentiviruses, such as equine infectious anemia and visna viruses. This finding, together with the cross-reactivity of the core proteins of LAV with those of the equine infectious anemia virus and a similarity in g...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-103-5-689

    authors: Montagnier L

    更新日期:1985-11-01 00:00:00