Residency training in internal medicine: time for a change?

abstract：OBJECTIVE:To determine, through structured methodologic review of published articles, the effectiveness of short-course (< or = 2 weeks) antibiotic therapy for catheter-related Staphylococcus aureus bacteremia. DATA SOURCES:English-language publications on catheter-related S. aureus bacteremia identified using MEDLINE...

journal_title：Annals of internal medicine

authors： Jernigan JA,Farr BM

更新日期：1993-08-15 00:00:00

abstract：BACKGROUND:The Department of Health and Human Services recently called for public comment on human subjects research protections. OBJECTIVE:To assess variability in reviews across institutional review boards (IRBs) for a multisite, minimal-risk trial of financial incentives for evidence-based hypertension care and to ...

journal_title：Annals of internal medicine

authors： Petersen LA,Simpson K,Sorelle R,Urech T,Chitwood SS

更新日期：2012-05-15 00:00:00

abstract：:Forty patients with systemic lupus erythematosus randomly received inactivated bivalent (A/NJ and A/Victoria) influenza vaccine or saline in a double-blind study. During 20 weeks of follow-up, no deterioration in major organ function or increase in disease flares was observed in the immunized group as compared with th...

journal_title：Annals of internal medicine

authors： Williams GW,Steinberg AD,Reinertsen JL,Klassen LW,Decker JL,Dolin R

更新日期：1978-06-01 00:00:00

abstract：:Population screening for hemochromatosis done by using the transferrin saturation test has been advocated by experts to permit the initiation of therapeutic phlebotomy before the onset of clinical disease. The discovery of a gene associated with hemochromatosis has made DNA testing another option for screening and dia...

journal_title：Annals of internal medicine

authors： Cogswell ME,McDonnell SM,Khoury MJ,Franks AL,Burke W,Brittenham G

更新日期：1998-12-01 00:00:00

abstract：:Chinese herbal medicine (CHM) formulas are the major components of traditional Chinese medicine (TCM) interventions. The general reporting quality of randomized controlled trials (RCTs) of CHM formulas is disappointing, although CONSORT (Consolidated Standards of Reporting Trials) Statement extensions for herbal medic...

journal_title：Annals of internal medicine

authors： Cheng CW,Wu TX,Shang HC,Li YP,Altman DG,Moher D,Bian ZX,CONSORT-CHM Formulas 2017 Group.

更新日期：2017-06-27 00:00:00

abstract：OBJECTIVE:To determine if polyvalent IgG is promising therapy for severe IgG nephropathy. DESIGN:Open prospective cohort study. SETTING:Referral nephrology unit. PATIENTS:11 adult patients with severe IgA nephropathy (9 who had idiopathic disease and 2 who had Henoch-Schönlein purpura) and indicators of poor prognos...

journal_title：Annals of internal medicine

authors： Rostoker G,Desvaux-Belghiti D,Pilatte Y,Petit-Phar M,Philippon C,Deforges L,Terzidis H,Intrator L,André C,Adnot S,Bonin P,Bierling P,Remy P,Lagrue G,Lang P,Weil B

更新日期：1994-03-15 00:00:00

abstract：OBJECTIVE:To assess the accuracy of Histoplasma capsulatum variety capsulatum polysaccharide antigen testing for the identification of histoplasmosis relapse in patients with the acquired immunodeficiency syndrome (AIDS). DESIGN:A retrospective study using stored specimens. SETTING:A referral center and several priva...

journal_title：Annals of internal medicine

authors： Wheat LJ,Connolly-Stringfield P,Blair R,Connolly K,Garringer T,Katz BP

更新日期：1991-12-15 00:00:00

abstract：OBJECTIVE:To determine the efficacy of ciprofloxacin therapy in eradicating convalescent fecal excretion of salmonellae after acute salmonellosis. DESIGN:Randomized, placebo-controlled, double-blind trial of ciprofloxacin, with prospective follow-up of nonparticipants. SETTING:An acute care community hospital experie...

journal_title：Annals of internal medicine

authors： Neill MA,Opal SM,Heelan J,Giusti R,Cassidy JE,White R,Mayer KH

更新日期：1991-02-01 00:00:00

abstract：:Adult salicylate intoxication has been considered to be easily recognized and assciated with low morbidity and mortality. In the present study of 73 consecutive adults hospitalized with salicylate intoxication, 27% of patients were undiagnosed for as long as 72 h after admission. The initial physical findings and labo...

journal_title：Annals of internal medicine

authors： Anderson RJ,Potts DE,Gabow PA,Rumack BH,Schrier RW

更新日期：1976-12-01 00:00:00

abstract：OBJECTIVE:To describe the course of rheumatoid arthritis over 5 years in adults and to evaluate the effect of parenterally administered gold salts on that course. DESIGN:A prospective observational study of adults with rheumatoid arthritis. Data derived from annual interviews with patients from 1983 to 1988 and from p...

journal_title：Annals of internal medicine

authors： Epstein WV,Henke CJ,Yelin EH,Katz PP

更新日期：1991-03-15 00:00:00

abstract：:Coronary artery spasm is an important pathogenetic mechanism in some forms of myocardial ischemic disease. Factors that may be important in the genesis of spasm include the autonomic nervous system, prostaglandins, endoperoxides, thromboxanes, and the calcium availability to the contractile apparatus. Spasm results in...

journal_title：Annals of internal medicine

authors： Luchi RJ,Chahine RA,Raizner AE

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVE:To provide a rational strategy for the evaluation and long-term management of epilepsy. DATA SOURCES:Articles written between 1964 and 1993, obtained from a MEDLINE search on epilepsy-related topics as well as from the author's personal files, major reference books on antiepileptic drugs, and references iden...

journal_title：Annals of internal medicine

authors： French J

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Prediction of perioperative cardiac complications is important in the medical management of patients undergoing noncardiac surgery. Several indices have been developed to aid prediction, but their performance has not been systematically compared. OBJECTIVE:To compare four existing methods for predicting per...

journal_title：Annals of internal medicine

authors： Gilbert K,Larocque BJ,Patrick LT

更新日期：2000-09-05 00:00:00

abstract：:Very low calorie diets used to treat moderate and severe obesity produce average weight losses of 20 kg in 12 weeks. This paper reviews the development of very low calorie diets from research on fasting in the late 1950s and examines data on the amount of dietary protein needed to achieve positive nitrogen balance. Th...

journal_title：Annals of internal medicine

authors： Wadden TA,Stunkard AJ,Brownell KD

更新日期：1983-11-01 00:00:00

abstract：:The second National Health and Nutrition Examination Survey found that 26% of U.S. adults, or about 34 million people aged 20 to 75 years, are overweight. The survey used a body mass index of 27.8 kg/m2 or greater for men and 27.3 or greater for women to define overweight. Prevalence of overweight increases with advan...

journal_title：Annals of internal medicine

authors： Van Itallie TB

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of minocycline in the treatment of rheumatoid arthritis. DESIGN:A double-blind, randomized, multicenter, 48-week trial of oral minocycline (200 mg/d) or placebo. SETTING:6 clinical centers in the United States. PATIENTS:219 adults with active rheumatoid arthritis who had p...

journal_title：Annals of internal medicine

authors： Tilley BC,Alarcón GS,Heyse SP,Trentham DE,Neuner R,Kaplan DA,Clegg DO,Leisen JC,Buckley L,Cooper SM,Duncan H,Pillemer SR,Tuttleman M,Fowler SE

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:Left bundle-branch block (BBB) is considered an important predictor of poor outcome in patients with acute myocardial infarction, but the consequences of right BBB are not well understood. OBJECTIVES:To 1) estimate the prevalence of left and right BBB in patients with myocardial infarction; 2) compare the c...

journal_title：Annals of internal medicine

authors： Go AS,Barron HV,Rundle AC,Ornato JP,Avins AL

更新日期：1998-11-01 00:00:00

abstract：:Plasma lipid and lipoprotein-cholesterol levels were measured in 10 insulin-dependent (Type I) diabetics taking their usual dose of conventionally administered insulin during 6 months of a continuous subcutaneous insulin infusion delivered with a small, portable, battery-powered pump. With this insulin delivery system...

journal_title：Annals of internal medicine

authors： Dunn FL,Pietri A,Raskin P

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Electrical cardioversion in patients with atrial fibrillation is associated with an increased risk for embolic stroke. Screening for atrial thrombi with transesophageal echocardiography (TEE) before cardioversion should, in many patients, safely permit cardioversion to be done earlier than would be possible ...

journal_title：Annals of internal medicine

authors： Klein AL,Grimm RA,Black IW,Leung DY,Chung MK,Vaughn SE,Murray RD,Miller DP,Arheart KL

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:The current standard initial therapies for deep venous thrombosis are low-molecular-weight heparin and unfractionated heparin. In a dose-ranging study of patients with symptomatic deep venous thrombosis, fondaparinux had efficacy and a safety profile similar to those of low-molecular-weight heparin (daltepar...

journal_title：Annals of internal medicine

authors： Büller HR,Davidson BL,Decousus H,Gallus A,Gent M,Piovella F,Prins MH,Raskob G,Segers AE,Cariou R,Leeuwenkamp O,Lensing AW,Matisse Investigators.

更新日期：2004-06-01 00:00:00

abstract：:Medical technology assessment seeks to improve the care of individual patients (the conventional unit of clinical practice) through evaluation studies conducted in groups of patients (the conventional unit of clinical investigation). This distinction between individuals and groups has practical relevance to the design...

journal_title：Annals of internal medicine

authors： Diamond GA,Denton TA

更新日期：1993-03-15 00:00:00

abstract：BACKGROUND:AL amyloidosis is a fatal disease resulting from tissue deposition of amyloid fibrils derived from monoclonal immunoglobulin light chains. Treatment with oral chemotherapy is minimally effective. OBJECTIVE:To test survival and organ response in a large sample of patients treated with high-dose intravenous m...

journal_title：Annals of internal medicine

authors： Skinner M,Sanchorawala V,Seldin DC,Dember LM,Falk RH,Berk JL,Anderson JJ,O'Hara C,Finn KT,Libbey CA,Wiesman J,Quillen K,Swan N,Wright DG

更新日期：2004-01-20 00:00:00

abstract：BACKGROUND:Although few retrospective studies of high altitude have reported that obesity might be associated with the development of acute mountain sickness (AMS), this association has not been studied prospectively. OBJECTIVE:To determine whether obesity is associated with the development of AMS. DESIGN:Obese and n...

journal_title：Annals of internal medicine

authors： Ri-Li G,Chase PJ,Witkowski S,Wyrick BL,Stone JA,Levine BD,Babb TG

更新日期：2003-08-19 00:00:00

abstract：BACKGROUND:Hyperuricemia is associated with risk for cardiovascular disease and death. However, the role of uric acid independent of established risk factors is uncertain. OBJECTIVE:To examine the relation of serum uric acid level to incident coronary heart disease, death from cardiovascular disease, and death from al...

journal_title：Annals of internal medicine

authors： Culleton BF,Larson MG,Kannel WB,Levy D

更新日期：1999-07-06 00:00:00

abstract：BACKGROUND:Increased prevalence of adolescent obesity requires effective treatment options beyond behavior therapy. OBJECTIVE:To see whether sibutramine reduced weight more than placebo in obese adolescents who were receiving a behavior therapy program. DESIGN:12-month, 3:1 randomized, double-blind trial conducted fr...

journal_title：Annals of internal medicine

authors： Berkowitz RI,Fujioka K,Daniels SR,Hoppin AG,Owen S,Perry AC,Sothern MS,Renz CL,Pirner MA,Walch JK,Jasinsky O,Hewkin AC,Blakesley VA,Sibutramine Adolescent Study Group.

更新日期：2006-07-18 00:00:00

abstract：OBJECTIVE:To define the temporal characteristics of cocaine-induced coronary vasoconstriction in humans and to assess the relation between cocaine-induced coronary vasoconstriction and the blood concentration of cocaine and its main metabolites. DESIGN:Randomized, double-blind, controlled clinical trial. SETTING:Card...

journal_title：Annals of internal medicine

authors： Brogan WC 3rd,Lange RA,Glamann DB,Hillis LD

更新日期：1992-04-01 00:00:00

abstract：:We treated 50 patients who ingested packets of cocaine and developed a protocol for conservative medical management. Of the 50 patients, only 3 required emergency surgery. Surgery was precipitated by signs and symptoms of bowel obstruction in all cases. Six patients chose elective surgery. The rest of the patients pas...

journal_title：Annals of internal medicine

authors： Caruana DS,Weinbach B,Goerg D,Gardner LB

更新日期：1984-01-01 00:00:00

abstract：:Given the low mortality and morbidity of the severe acute respiratory syndrome (SARS) compared with other public health scourges, is the attention devoted to it misdirected? The SARS experience has provided at least 4 enduring lessons. First, by providing a test of the capacity of each part of the public health system...

journal_title：Annals of internal medicine

authors： Emanuel EJ

更新日期：2003-10-07 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of intravenous adenosine in terminating acute episodes of paroxysmal supraventricular tachycardia. DESIGN:Two prospective, double-blind, randomized, placebo-controlled trials to evaluate dose response in patients receiving adenosine and to compare the effects of adenosine wi...

journal_title：Annals of internal medicine

authors： DiMarco JP,Miles W,Akhtar M,Milstein S,Sharma AD,Platia E,McGovern B,Scheinman MM,Govier WC

更新日期：1990-07-15 00:00:00

abstract：:A cohort of both active and retired older cotton textile workers was examined prospectively over a 6-year period to establish the nature and extent of chronic lung disease. Respiratory symptoms and lung function were studied in these workers and in a group of similarly aged controls. The cotton textile workers had hig...

journal_title：Annals of internal medicine

authors： Beck GJ,Schachter EN,Maunder LR,Schilling RS

更新日期：1982-11-01 00:00:00