In type 2 diabetes, some glucose-lowering drugs reduce HbA1c more than others; drugs do not differ for mortality.

abstract：BACKGROUND:Adiponectin and resistin are recently discovered adipokines that may provide a molecular link between adiposity and type 2 diabetes. OBJECTIVE:To evaluate whether total and high-molecular-weight adiponectin and resistin are associated with future risk for type 2 diabetes, independent of obesity and other kn...

journal_title：Annals of internal medicine

authors： Heidemann C,Sun Q,van Dam RM,Meigs JB,Zhang C,Tworoger SS,Mantzoros CS,Hu FB

更新日期：2008-09-02 00:00:00

abstract：Background:In 1994, 40% of U.S. gun owners who had recently acquired a firearm did so without a background check. No contemporary estimates exist. Objective:To estimate the proportion of current U.S. gun owners who acquired their most recent firearm without a background check, by time since and manner of acquisition, ...

journal_title：Annals of internal medicine

authors： Miller M,Hepburn L,Azrael D

更新日期：2017-02-21 00:00:00

abstract：:Patients with variant angina refractory to medical therapy pose a difficult management problem. We report two patients with variant angina who had focal spasm in coronary arteries with fixed obstructions of less than 20% of the luminal diameter. Ischemic episodes were accompanied by malignant ventricular arrhythmias a...

journal_title：Annals of internal medicine

authors： Sussman EJ,Goldberg S,Poll DS,MacVaugh H 3rd,Simson MB,Silber SA,Kastor JA

更新日期：1981-06-01 00:00:00

abstract：:Giant cell tumor of bone is a rare, but well-recognized complication of Paget's disease of bone. In contrast, giant cell reparative granuloma (a benign tumor of the jaws occurring primarily in young adults) has never been described in association with Paget's disease. Five patients had giant cell lesions complicating ...

journal_title：Annals of internal medicine

authors： Upchurch KS,Simon LS,Schiller AL,Rosenthal DI,Campion EW,Krane SM

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Longer-term mortality benefit and cost-effectiveness for abdominal aortic aneurysm (AAA) screening are uncertain. OBJECTIVE:To estimate the benefits, in terms of AAA-related and all-cause mortality, and cost-effectiveness of ultrasonography screening for AAA in a group that was invited to screening compared...

journal_title：Annals of internal medicine

authors： Kim LG,P Scott RA,Ashton HA,Thompson SG,Multicentre Aneurysm Screening Study Group.

更新日期：2007-05-15 00:00:00

abstract：:Since 1970, forty-two patients with pulmonary hypertension due to chronic, thromboembolic obstruction of the major pulmonary arteries have had pulmonary thromboendarterectomy at the University of California, San Diego, and the San Diego Veterans Medical Centers. Duration of symptoms before admission averaged 4.4 years...

journal_title：Annals of internal medicine

authors： Moser KM,Daily PO,Peterson K,Dembitsky W,Vapnek JM,Shure D,Utley J,Archibald C

更新日期：1987-10-01 00:00:00

abstract：:Two-dimensional echocardiograms were done during rest and after exercise in 95 patients who subsequently had coronary arteriography. Prior myocardial infarction was present in 36 patients, 35 of whom had wall motion abnormalities. There was no evidence of prior infarction in 59 patients, 44 of whom had coronary diseas...

journal_title：Annals of internal medicine

authors： Armstrong WF,O'Donnell J,Dillon JC,McHenry PL,Morris SN,Feigenbaum H

更新日期：1986-12-01 00:00:00

abstract：:When cytotoxic agents were introduced, their ability to disrupt nucleic acid and protein synthesis led to their effective use for the treatment of neoplastic disease. During the course of this use, however, it became apparent that these agents also suppress the immune system. This usually unwelcome effect was subseque...

journal_title：Annals of internal medicine

authors： Langford CA,Klippel JH,Balow JE,James SP,Sneller MC

更新日期：1998-07-01 00:00:00

abstract：:This article applies major economic concepts, such as supply, demand, monopoly, monopsony, adverse selection, and moral hazard, to central features of U.S. health care. These illustrations help explain some of the principal problems of health policy-high cost and the uninsured-and why solutions are difficult to obtain...

journal_title：Annals of internal medicine

authors： Fuchs VR

更新日期：2015-03-03 00:00:00

abstract：OBJECTIVE:To determine whether self-assessment of purified protein derivative of tuberculin (PPD) skin test reactions, done using a simple two-choice approach, is an effective screening method for tuberculosis. DESIGN:Double-blind comparison between self-assessments and trained professional readings of PPD skin test r...

journal_title：Annals of internal medicine

authors： Prezant DJ,Kelly KJ,Karwa ML,Kavanagh K

更新日期：1996-08-15 00:00:00

abstract：:In April 1976 the attack rate of chills and fever with or without falls in blood pressure increased in association with cardiac catheterizations. Fevers were associated with coronary angiography and right and left heart catheterizations. Blood cultures were negative, and reactions did not correlate with amounts of con...

journal_title：Annals of internal medicine

authors： Reyes MP,Ganguly S,Fowler M,Brown WJ,Gatmaitan BG,Friedman C,Lerner AM

更新日期：1980-07-01 00:00:00

abstract：:This issue provides a clinical overview of Clostridium difficile infection focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits. Only ACP members and individual subscribers can access the electronic features of In th...

journal_title：Annals of internal medicine

authors： Hessen MT

更新日期：2010-10-05 00:00:00

abstract：OBJECTIVE:To determine in female tennis and squash players the effect of biological age (that is, the starting age of playing relative to the age at menarche) at which tennis or squash playing was started on the difference in bone mineral content between the playing and non-playing arms. DESIGN:Cross-sectional study. ...

journal_title：Annals of internal medicine

authors： Kannus P,Haapasalo H,Sankelo M,Sievänen H,Pasanen M,Heinonen A,Oja P,Vuori I

更新日期：1995-07-01 00:00:00

abstract：:Poststreptococcal acute glomerulonephritis is prototypic of the immunologic glomerulonephritides. It most commonly follows streptococcal infection of the pharynx or skin. The diagnosis is usually not difficult when a nephritic clinical presentation (with such manifestations as hematuria, edema, and hypertension) is as...

journal_title：Annals of internal medicine

authors： Nissenson AR,Baraff LJ,Fine RN,Knutson DW

更新日期：1979-07-01 00:00:00

abstract：:Behavior modification applied to the treatment of obesity has evolved from the environmental control of eating behavior to a broader approach characterized by systematic manipulation of all factors associated with eating and exercise patterns. This approach has shown success in helping obese persons lose modest amount...

journal_title：Annals of internal medicine

authors： Foreyt JP,Goodrick GK

更新日期：1993-10-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the efficacy of the addition of ifosfamide to cisplatin plus etoposide (VIP), or vinblastine (VeIP), in patients with recurrent germ cell tumors. DESIGN:Nonrandomized, prospective phase II trial. SETTING:Tertiary referral university hospital. PATIENTS:Fifty-six of fifty-eight entered pat...

journal_title：Annals of internal medicine

authors： Loehrer PJ Sr,Lauer R,Roth BJ,Williams SD,Kalasinski LA,Einhorn LH

更新日期：1988-10-01 00:00:00

abstract：:After decades of silence, the German Society for Internal Medicine (DGIM) has made considerable efforts to come to terms with its role and actions during the Nazi era (1933 to 1945). This is particularly important because, with more than 27 000 members, the DGIM is the largest medical society in present-day Germany. S...

journal_title：Annals of internal medicine

authors： Hofer HG,Forsbach R,Fölsch UR

更新日期：2020-09-01 00:00:00

abstract：:Past efforts to reverse or limit the effects of acute stroke have been largely unsuccessful, in part because of the inability to evaluate and treat most patients soon after stroke onset. One important factor in the delay of treatment has been the nihilistic attitude of medical personnel, including physicians, toward t...

journal_title：Annals of internal medicine

authors：

更新日期：1995-04-15 00:00:00

abstract：BACKGROUND:Soon, half of all physicians may be married to other physicians (that is, in dual-doctor families). Little is known about how marriage to another physician affects physicians themselves. OBJECTIVE:To learn how physicians in dual-doctor families differ from other physicians in their professional and family l...

journal_title：Annals of internal medicine

authors： Sobecks NW,Justice AC,Hinze S,Chirayath HT,Lasek RJ,Chren MM,Aucott J,Juknialis B,Fortinsky R,Youngner S,Landefeld CS

更新日期：1999-02-16 00:00:00

abstract：OBJECTIVE:To determine the relations among esophageal dysfunction, gastroesophageal reflux, and lung involvement in patients with systemic sclerosis. DESIGN:Retrospective review of esophageal motility, esophageal pH, and pulmonary function data. SETTING:University hospital outpatient clinic and community. PATIENTS:3...

journal_title：Annals of internal medicine

authors： Troshinsky MB,Kane GC,Varga J,Cater JR,Fish JE,Jimenez SA,Castell DO

更新日期：1994-07-01 00:00:00

abstract：:Imaging under loading stress is hypothesized to improve the diagnostic value of magnetic resonancel imaging (MRI) for musculoskeletal conditions. This article reviews 57 studies about MRI under physiologic loading stress performed in an upright or sitting position or under axial loading by using a compression device. ...

journal_title：Annals of internal medicine

authors： Dahabreh IJ,Hadar N,Chung M

更新日期：2011-11-01 00:00:00

abstract：:For over 200 years digitalis compounds have been used to treat atrial fibrillation. The rapid ventricular response to atrial fibrillation is frequently treated with digoxin to produce a controlled heart rate. Digoxin has also been proposed as a treatment for terminating recent-onset atrial fibrillation, for maintainin...

journal_title：Annals of internal medicine

authors： Falk RH,Leavitt JI

更新日期：1991-04-01 00:00:00

abstract：:Active-control noninferiority trials are being performed with increasing frequency when standard placebo-controlled trials are considered unethical. Three attributes are optimally required to establish noninferiority: 1) The treatment under consideration exhibits therapeutic noninferiority to the active control; 2) th...

journal_title：Annals of internal medicine

authors： Kaul S,Diamond GA

更新日期：2006-07-04 00:00:00

abstract：BACKGROUND:HIV-infected patients with sustained immunologic improvement from antiretroviral therapy may be able to discontinue chemoprophylaxis against Pneumocystis carinii pneumonia (PCP). OBJECTIVE:To compare PCP incidence in HIV-infected patients who had sustained CD4+ lymphocyte counts greater than 200 cells/mm3 a...

journal_title：Annals of internal medicine

authors： Yangco BG,Von Bargen JC,Moorman AC,Holmberg SD

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Travelers' diarrhea causes substantial morbidity and postinfectious irritable bowel syndrome. OBJECTIVE:To evaluate nonabsorbable rifaximin for prevention of travelers' diarrhea. DESIGN:Randomized, double-blind, placebo-controlled clinical trial. SETTING:Guadalajara, Mexico. PARTICIPANTS:U.S. students. ...

journal_title：Annals of internal medicine

authors： DuPont HL,Jiang ZD,Okhuysen PC,Ericsson CD,de la Cabada FJ,Ke S,DuPont MW,Martinez-Sandoval F

更新日期：2005-05-17 00:00:00

abstract：:The U.S. Food and Drug Administration (FDA) Amendments Act of 2007 mandated that the FDA develop a system for using automated health care data to identify risks of marketed drugs and other medical products. The Observational Medical Outcomes Partnership is a public-private partnership among the FDA, academia, data own...

journal_title：Annals of internal medicine

authors： Stang PE,Ryan PB,Racoosin JA,Overhage JM,Hartzema AG,Reich C,Welebob E,Scarnecchia T,Woodcock J

更新日期：2010-11-02 00:00:00

abstract：OBJECTIVE:To evaluate the 6-month change in cardiovascular (coronary heart disease) risk as a function of diet and drug therapy for mild hypertension. DESIGN:Collaborative randomized, controlled clinical trial to assess the efficacy of alternative regimens in treating mild hypertension. SETTING:Three university-based...

journal_title：Annals of internal medicine

authors： Oberman A,Wassertheil-Smoller S,Langford HG,Blaufox MD,Davis BR,Blaszkowski T,Zimbaldi N,Hawkins CM

更新日期：1990-01-15 00:00:00

abstract：BACKGROUND:ClinicalTrials.gov requires reporting of result summaries for many drug and device trials. PURPOSE:To evaluate the consistency of reporting of trials that are registered in the ClinicalTrials.gov results database and published in the literature. DATA SOURCES:ClinicalTrials.gov results database and matched ...

journal_title：Annals of internal medicine

authors： Hartung DM,Zarin DA,Guise JM,McDonagh M,Paynter R,Helfand M

更新日期：2014-04-01 00:00:00

abstract：:A 20-year follow-up evaluation of young men with fixed and reproducible orthostatic proteinuria showed no evidence of progressive renal disease. Follow-up information was obtained on 43 of the original 64 patients and detailed information was secured on 36. All had normal renal function and only six patients continued...

journal_title：Annals of internal medicine

authors： Springberg PD,Garrett LE Jr,Thompson AL Jr,Collins NF,Lordon RE,Robinson RR

更新日期：1982-10-01 00:00:00

abstract：Background:Central line-associated bloodstream infection (CLABSI) remains prevalent in hospitals in the United States. Objective:To evaluate the impact of a multimodal intervention in hospitals with elevated rates of health care-associated infection. Design:Pre-post observational evaluation of a prospective, national...

journal_title：Annals of internal medicine

authors： Patel PK,Greene MT,Jones K,Rolle AJ,Ratz D,Snyder A,Saint S,Chopra V

更新日期：2019-10-01 00:00:00