Discontinuation of chemoprophylaxis against Pneumocystis carinii pneumonia in patients with HIV infection. HIV Outpatient Study (HOPS) Investigators.

abstract：:During the early 1990s, the U.S. government addressed the issue of providing universal health care to all its citizens. Although this issue has not been completely resolved, centralization of electronic data and sharing of health care information among insurers and providers have been pursued. The emergence of electro...

journal_title：Annals of internal medicine

authors： Gostin L

更新日期：1997-10-15 00:00:00

abstract：Background:Whether statin type influences hepatocellular carcinoma (HCC) incidence or mortality in chronic hepatitis B or C virus infection is unknown. Objective:To assess the relationship between lipophilic or hydrophilic statin use and HCC incidence and mortality in a nationwide population with viral hepatitis. Des...

journal_title：Annals of internal medicine

authors： Simon TG,Duberg AS,Aleman S,Hagstrom H,Nguyen LH,Khalili H,Chung RT,Ludvigsson JF

更新日期：2019-09-03 00:00:00

abstract：:A retrospective analysis of the course of systemic lupus erythematosus in pregnant patients hospitalized at UCLA during a 15-year period provided important prognostic information. Women with systemic lupus erythematosus became pregnant if renal function was reasonably well preserved. Pregnancy infrequently posed a ser...

journal_title：Annals of internal medicine

authors：

更新日期：1981-05-01 00:00:00

abstract：:Thyroid antibodies were found significantly more often in insulin-dependent diabetics than in their spouses or in non-insulin-dependent diabetics. The poor correlation between presence of thyroid autoimmunity and duration of disease and the significantly increased prevalence of thyroid antibodies in first-degree relat...

journal_title：Annals of internal medicine

authors： Fialkow PJ,Zavala C,Nielsen R

更新日期：1975-08-01 00:00:00

abstract：:We performed immunohistopathologic studies on biopsied lung tissue obtained from two patients with lupus pneumonitis using immunofluorescence, immunoperoxidase, electron microscopy, and acid-microelution. In both patients, immunofluorescence showed granular deposits of IgG, the third component of complement (C3), and ...

journal_title：Annals of internal medicine

authors： Inoue T,Kanayama Y,Ohe A,Kato N,Horiguchi T,Ishii M,Shiota K

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:It has been reported that walnuts reduce serum cholesterol levels in normal young men. OBJECTIVE:To assess the acceptability of walnuts and their effects on serum lipid levels and low-density lipoprotein (LDL) oxidizability in free-living hypercholesterolemic persons. DESIGN:Randomized, crossover feeding t...

journal_title：Annals of internal medicine

authors： Zambón D,Sabaté J,Muñoz S,Campero B,Casals E,Merlos M,Laguna JC,Ros E

更新日期：2000-04-04 00:00:00

abstract：BACKGROUND:The standard diagnostic approach in patients suspected of having pulmonary embolism starts with perfusion-ventilation lung scanning. If the resulting scan is not diagnostic, pulmonary angiography should be done. The use of tests for deep venous thrombosis has been advocated as an adjunct to establishing the ...

journal_title：Annals of internal medicine

authors： Turkstra F,Kuijer PM,van Beek EJ,Brandjes DP,ten Cate JW,Büller HR

更新日期：1997-05-15 00:00:00

abstract：:An investigation of patient care in four hospitals compared levels of resource use between 1964 and 1974 for patients with a primary diagnosis of pneumonia. Results showed a decreased length of stay in all hospitals. Unique patterns of increases and decreases existed in each hospital for the changing use of diagnostic...

journal_title：Annals of internal medicine

authors： Sheeley DR,Sherman H

更新日期：1976-11-01 00:00:00

abstract：:We evaluated the usefulness of computed tomography (CT) brain scanning in alcoholic patients with withdrawal seizures (n = 151) and other neurologic problems (n = 87) and compared the findings of a detailed neurologic examination to the results of CT scanning. In patients with seizures, nearly 50% of CT scans were nor...

journal_title：Annals of internal medicine

authors： Feussner JR,Linfors EW,Blessing CL,Starmer CF

更新日期：1981-04-01 00:00:00

abstract：:To increase the utility of administrative databases, it has been recommended that they include disease-specific, patient-centered outcome measures. This paper reviews practical and theoretical considerations and the critical evidence to support this recommendation. The strengths and weaknesses of the recommended appro...

journal_title：Annals of internal medicine

authors： Liang MH,Shadick N

更新日期：1997-10-15 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the usefulness and safety of hydroxychloroquine in patients with decompensated, treatment-refractory noninsulin-dependent diabetes mellitus. DESIGN:Prospective, randomized, placebo, double-blind 6-month trial. PATIENTS:Thirty-eight patients with noninsulin-dependent diabetes resistant to c...

journal_title：Annals of internal medicine

authors： Quatraro A,Consoli G,Magno M,Caretta F,Nardozza A,Ceriello A,Giugliano D

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Mounting evidence indicates that subclinical thyroid dysfunction has important clinical effects and prognostic implications, supporting the view that it is not a compensated biochemical change sensu strictu. PURPOSE:To review clinical information on the effects of subclinical thyroid dysfunction on the hear...

journal_title：Annals of internal medicine

authors： Biondi B,Palmieri EA,Lombardi G,Fazio S

更新日期：2002-12-03 00:00:00

abstract：:Tetanus is an expected complication when disasters strike in developing countries, where tetanus immunization coverage is often low or nonexistent. Collapsing structures and swirling debris inflict numerous crush injuries, fractures, and serious wounds. Clostridium tetani infects wounds contaminated with dirt, feces, ...

journal_title：Annals of internal medicine

authors： Afshar M,Raju M,Ansell D,Bleck TP

更新日期：2011-03-01 00:00:00

abstract：:Several trends in medical education affect our supply of future physicians. The number of new physicians has increased so that each year there is an excess of about 6000 over the number of physicians produced per year a decade ago. Increasing numbers of women and members of minority groups are entering the profession ...

journal_title：Annals of internal medicine

authors： Cooper JA

更新日期：1978-11-01 00:00:00

abstract：:The second National Health and Nutrition Examination Survey found that 26% of U.S. adults, or about 34 million people aged 20 to 75 years, are overweight. The survey used a body mass index of 27.8 kg/m2 or greater for men and 27.3 or greater for women to define overweight. Prevalence of overweight increases with advan...

journal_title：Annals of internal medicine

authors： Van Itallie TB

更新日期：1985-12-01 00:00:00

abstract：:Our review focuses on low density lipoprotein (LD lipoprotein) and very low density lipoprotein (VLD lipoprotein) in their roles as transporters of cholesterol and triglyceride and as factors contributing to premature arteriovascular disease. We describe the clinical manifestations of the common, primary hyperlipoprot...

journal_title：Annals of internal medicine

authors： Fisher WR,Truitt DH

更新日期：1976-10-01 00:00:00

abstract：:Thirty-two studies (2889 subjects) that investigated the prevalence of the causes of dementia were critically reviewed. Particular attention was paid to potential and actual reversibility. Although dementia manifests itself primarily in old age (particularly age 75 and older), the mean age of patients for the studies ...

journal_title：Annals of internal medicine

authors： Clarfield AM

更新日期：1988-09-15 00:00:00

abstract：OBJECTIVE:To determine the effects of fluvastatin, a synthetic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, combined with moderate alcohol consumption on lipid profiles and hepatic function in patients with primary hypercholesterolemia. DESIGN:Randomized, placebo-controlled, crossover study. S...

journal_title：Annals of internal medicine

authors： Smit JW,Wijnne HJ,Schobben F,Sitsen A,De Bruin TW,Erkelens DW

更新日期：1995-05-01 00:00:00

abstract：:Arteriohepatic dysplasia (Alagille's syndrome) is presumed to be one of the familial intrahepatic cholestatic syndromes, all of which present with neonatal jaundice or failure to thrive, or both. We report the findings in five patients with this syndrome, four of whom have been followed into adulthood. In addition to ...

journal_title：Annals of internal medicine

authors： Riely CA,Cotlier E,Jensen PS,Klatskin G

更新日期：1979-10-01 00:00:00

abstract：Background:Probiotics, prebiotics, and synbiotics are used increasingly, although the safety and potential harms of these interventions are poorly understood. Purpose:To examine how harms-related information is reported in publications of randomized controlled trials (RCTs) of probiotics, prebiotics, and synbiotics. ...

journal_title：Annals of internal medicine

authors： Bafeta A,Koh M,Riveros C,Ravaud P

更新日期：2018-08-21 00:00:00

abstract：BACKGROUND:The Department of Health and Human Services recently called for public comment on human subjects research protections. OBJECTIVE:To assess variability in reviews across institutional review boards (IRBs) for a multisite, minimal-risk trial of financial incentives for evidence-based hypertension care and to ...

journal_title：Annals of internal medicine

authors： Petersen LA,Simpson K,Sorelle R,Urech T,Chitwood SS

更新日期：2012-05-15 00:00:00

abstract：:Four hundred sixty patients and staff from 15 U.S. dialysis centers were surveyed by the immune adherence hemagglutination technique for antibody to hepatitis A antigen (anti-HA). The age-standardized anti-HA prevalence was 42.9% in patients and 42.1% in staff. These rates are almost identical to those of socioeconomi...

journal_title：Annals of internal medicine

authors： Szmuness W,Dienstag JL,Purcell RH,Prince AM,Stevens CE,Levine RW

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Impressive decreases in cardiovascular mortality have been achieved through risk factor reduction and clinical intervention, yet cardiovascular disease remains a leading cause of death nationally. OBJECTIVE:To estimate up-to-date preventable fractions of cardiovascular mortality associated with elimination ...

journal_title：Annals of internal medicine

authors： Patel SA,Winkel M,Ali MK,Narayan KM,Mehta NK

更新日期：2015-08-18 00:00:00

abstract：Background:Little is known about whether insurance expansion affects the location and type of emergency department (ED) use. Understanding these changes can inform state-level decisions about the Medicaid expansion under the Patient Protection and Affordable Care Act (ACA). Objective:To investigate the effect of the 2...

journal_title：Annals of internal medicine

authors： Garthwaite C,Gross T,Notowidigdo M,Graves JA

更新日期：2017-02-07 00:00:00

abstract：BACKGROUND:U.S. HIV treatment guidelines recommend branded once-daily, 1-pill efavirenz-emtricitabine-tenofovir as first-line antiretroviral therapy (ART). With the anticipated approval of generic efavirenz in the United States, a once-daily, 3-pill alternative (generic efavirenz, generic lamivudine, and tenofovir) wil...

journal_title：Annals of internal medicine

authors： Walensky RP,Sax PE,Nakamura YM,Weinstein MC,Pei PP,Freedberg KA,Paltiel AD,Schackman BR

更新日期：2013-01-15 00:00:00

abstract：:Forceful new demands for accountability in medicine are arising from many interested parties. To maintain professional standards, physicians need to establish which demands are desirable and which are not. We adopt a model of stratified accountability that includes three major components: the accountable parties, the ...

journal_title：Annals of internal medicine

authors： Emanuel LL

更新日期：1996-01-15 00:00:00

abstract：:Research on assessing or managing medication adherence applies approaches from observational, interventional, and implementation science that spans many disciplines and demands coherent conceptualization, valid methods, appropriate analyses, and complete and accurate reporting. To ensure such reporting, the European S...

journal_title：Annals of internal medicine

authors： De Geest S,Zullig LL,Dunbar-Jacob J,Helmy R,Hughes DA,Wilson IB,Vrijens B

更新日期：2018-07-03 00:00:00

abstract：OBJECTIVE:To determine the effect of the presence of a patent foramen ovale on the right-to-left shunt in patients with respiratory failure who receive positive end-expiratory pressure (PEEP). DESIGN:Convenience sample with randomized application of PEEP. SETTING:General intensive care unit of a university teaching h...

journal_title：Annals of internal medicine

authors： Cujec B,Polasek P,Mayers I,Johnson D

更新日期：1993-11-01 00:00:00

abstract：STUDY OBJECTIVE:To define the prevalence, severity, type and pathogenesis of osteopenia in idiopathic hemochromatosis. DESIGN:Prospective study conducted over 18 months. SETTING:Tertiary care center. SUBJECTS:Twenty-two men with idiopathic hemochromatosis and 20 age-matched controls. There were 5 hypogonadal patient...

journal_title：Annals of internal medicine

authors： Diamond T,Stiel D,Posen S

更新日期：1989-03-15 00:00:00

abstract：:Population screening for hemochromatosis done by using the transferrin saturation test has been advocated by experts to permit the initiation of therapeutic phlebotomy before the onset of clinical disease. The discovery of a gene associated with hemochromatosis has made DNA testing another option for screening and dia...

journal_title：Annals of internal medicine

authors： Cogswell ME,McDonnell SM,Khoury MJ,Franks AL,Burke W,Brittenham G

更新日期：1998-12-01 00:00:00