Hormonal regulation of the synthesis of lamellar body phosphatidylglycerol and phosphatidylinositol in fetal lung tissue.

abstract：:Obesity and its associated comorbidities are of major worldwide concern. It is now recognized that there are a number of metabolically distinct pathways of obesity development. The present paper investigates the effect of moderate daily exercise on the underlying mechanisms of one such pathway to obesity, through inte...

journal_title：Endocrinology

authors： Miles JL,Huber K,Thompson NM,Davison M,Breier BH

更新日期：2009-01-01 00:00:00

abstract：:Glucocorticoids and nonsteroidal antiinflammatory drugs (NSAIDs) are widely used for the treatment of inflammatory and immune diseases. Nitric oxide (NO) has a diversity of physiological functions, but its excess production has been implicated in the inflammatory process. The present study was designed to elucidate th...

journal_title：Endocrinology

authors： Katsuyama K,Shichiri M,Kato H,Imai T,Marumo F,Hirata Y

更新日期：1999-05-01 00:00:00

abstract：:Primary functional bovine adrenal cortical cell cultures have been developed to study the factors controlling adrenal cell growth. Cells were prepared by the collagenase technique and maintained in F-12 medium containing fetal calf serum and horse serum. Cells contained abundant lipid as demonstrated by staining with ...

journal_title：Endocrinology

authors： Gospodarowicz D,Ill CR,Hornsby PJ,Gill GN

更新日期：1977-04-01 00:00:00

abstract：:Brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) are present in brain regions regulating LH secretion. Similarities in the molecular structure of these peptides suggest similar physiological function within the brain. This study examined the effects of centrally administered BNP and ANP on LH secre...

journal_title：Endocrinology

authors： Zhang J,Yuen BH,Currie WD,Leung PC

更新日期：1991-08-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF), a pleiotropic cytokine localized within the ovary, alters follicular steroidogenesis. Preovulatory follicles dissected from ovaries of normal cyclic adult rats on the morning of proestrus exhibit steroidogenic and histological signs of atresia after 24 h of culture under the conditio...

journal_title：Endocrinology

authors： Roby KF,Terranova PF

更新日期：1990-05-01 00:00:00

abstract：:The concentration-activity profiles for insulin and insulin-like growth factor I (IGF-I; in the presence of and insulin-like growth factor I (IGF-I; in the presence of hydrocortisone and PRL) have been compared in terms of the accumulation of beta-casein mRNA, total casein synthesis, and alpha-lactalbumin and basal ca...

journal_title：Endocrinology

authors： Prosser CG,Sankaran L,Hennighausen L,Topper YJ

更新日期：1987-04-01 00:00:00

abstract：:The effect of beta-endorphin upon plasma arg8-vasopressin release was studied in vivo in rabbits and in vitro in rat neural lobes. Following intravenous administration of 200 mug/kg synthetic beta-endorphin plasma AVP rose significantly by five minutes after injection and remained elevated for twenty-five minutes comp...

journal_title：Endocrinology

authors： Weitzman RE,Fisher DA,Minick S,Ling N,Guillemin R

更新日期：1977-11-01 00:00:00

abstract：:The purpose of these experiments was to test the hypothesis that estrogen has an anabolic effect on cancellous bone formation in long bones of growing rats. In the present studies, estrogen decreased measurements related to cancellous bone formation, including osteoblast number, fluorochrome-labeled bone perimeter, an...

journal_title：Endocrinology

authors： Westerlind KC,Wakley GK,Evans GL,Turner RT

更新日期：1993-12-01 00:00:00

abstract：:Previous studies established a positive relationship between oocyte competence and follistatin mRNA abundance. Herein, we used the bovine model to test the hypothesis that follistatin plays a functional role in regulation of early embryogenesis. Treatment of early embryos with follistatin during in vitro culture (befo...

journal_title：Endocrinology

authors： Lee KB,Bettegowda A,Wee G,Ireland JJ,Smith GW

更新日期：2009-05-01 00:00:00

abstract：:Neuromedin-N (NN) and neurotensin (NT) were shown recently to be encoded in the same precursor molecule. Colocalization and corelease of ileal NT and NN have not yet been demonstrated and were investigated in the rat using antisera that separately recognized intact NT and NN in ileal extracts. Immunofluorescence label...

journal_title：Endocrinology

authors： Cuber JC,Herrmann C,Kitabgi P,Bosshard A,Bernard C,De Nadai F,Chayvialle JA

更新日期：1990-03-01 00:00:00

abstract：:The present studies demonstrate that the murine adrenocortical tumor cell line Y-1 releases a digoxin-like immunoreactive material into both serum-supplemented nutrient medium and minimal Krebs-Ringer bicarbonate medium. Release of pregnenolone into minimal medium from these cells was consistently inhibited by additio...

journal_title：Endocrinology

authors： Doris PA,Kilgore MW,Durham D,Alberts D,Stocco DM

更新日期：1989-11-01 00:00:00

abstract：:Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is known about the direct effect of caffeine on normal trophoblast ...

journal_title：Endocrinology

authors： Grant I,Cartwright JE,Lumicisi B,Wallace AE,Whitley GS

更新日期：2012-09-01 00:00:00

abstract：:Previous studies have suggested that the ovary produces a factor that maintains the pituitary in a state of low LHRH responsiveness that must be overcome by the self-priming action of LHRH. To determine the role of inhibin in maintaining low LHRH responsiveness in pituitaries of diestrous female rats, endogenous inhib...

journal_title：Endocrinology

authors： Culler MD

更新日期：1992-03-01 00:00:00

abstract：:It is known that the circadian rhythm in hepatic phosphoenolpyruvate carboxykinase expression (a limiting catalytic step of gluconeogenesis) and hepatic glucose production is maintained by both daily oscillation in autonomic inputs to the liver and night feeding behavior. However, increased glycemia and reduced melato...

journal_title：Endocrinology

authors： Nogueira TC,Lellis-Santos C,Jesus DS,Taneda M,Rodrigues SC,Amaral FG,Lopes AM,Cipolla-Neto J,Bordin S,Anhê GF

更新日期：2011-04-01 00:00:00

abstract：:We previously reported anatomical and functional evidence for a direct, inhibitory neural pathway that regulates testosterone (T) secretion independently of the pituitary. This pathway is activated by the intracerebroventricular (icv) administration of agents that stimulate stress responses, such as IL-1beta, corticot...

journal_title：Endocrinology

authors： Selvage DJ,Parsons L,Rivier C

更新日期：2006-06-01 00:00:00

abstract：:Recent observations suggest a role for interleukin-1 (IL-1), a polypeptide product of macrophage/monocytic cells, in the immune-mediated destruction of pancreatic islet beta-cells observed in type 1 diabetes. In this study, we investigated the effects of IL-1 on both alpha- and beta-cell secretory functions in rat isl...

journal_title：Endocrinology

authors： Rabinovitch A,Pukel C,Baquerizo H

更新日期：1988-06-01 00:00:00

abstract：:The hormonal control of the adipose conversion of 3T3 L1 cells was studied in a chemically defined medium and compared to that under serum-containing conditions. Addition of insulin to a chemically defined medium (Dulbecco's Modified Eagle's Medium-Ham's F-12, 1:1) resulted in a dose-dependent increase in glycero-3-ph...

journal_title：Endocrinology

authors： Hauner H

更新日期：1990-08-01 00:00:00

abstract：:Flavonoids are functional constituents of many fruits and vegetables. Some flavonoids have antidiabetic properties because they improve altered glucose and oxidative metabolisms of diabetic states. Procyanidins are flavonoids with an oligomeric structure, and it has been shown that they can improve the pathological ox...

journal_title：Endocrinology

authors： Pinent M,Blay M,Bladé MC,Salvadó MJ,Arola L,Ardévol A

更新日期：2004-11-01 00:00:00

abstract：:Dopamine D2 receptor agonists are commonly used in the control of PRL-secreting adenomas, and the sensitivity of dopamine agonists during long term therapy is exquisite. However, the molecular mechanisms responsible for the maintenance of this cellular sensitivity to dopamine agonists remain poorly understood. In the ...

journal_title：Endocrinology

authors： Ng GY,Varghese G,Chung HT,Trogadis J,Seeman P,O'Dowd BF,George SR

更新日期：1997-10-01 00:00:00

abstract：:We previously showed that receptor-like protein tyrosine phosphatase (RPTP)-alpha inhibited insulin-increased prolactin gene transcription. Others suggested that RPTPalpha was a key intermediary between integrins and activation of Src. We present evidence that inhibition of insulin-increased prolactin gene transcripti...

journal_title：Endocrinology

authors： Vulin AI,Jacob KK,Stanley FM

更新日期：2005-08-01 00:00:00

abstract：:11beta-hydroxysteroid dehydrogenases (11betaHSDs) catalyze interconversion of 11-hydroxy-glucocorticoids with inactive 11-keto metabolites. In blood vessel walls, loss of 11betaHSD1 is thought to reduce local glucocorticoid concentrations, reducing the progression of atheroma and enhancing angiogenesis. Conversely, on...

journal_title：Endocrinology

authors： Dover AR,Hadoke PW,Macdonald LJ,Miller E,Newby DE,Walker BR

更新日期：2007-01-01 00:00:00

abstract：:To elucidate the metabolic fate and possible role of androgens and their derivatives during primate fetal development, aromatase (AROM), 5 alpha-reductase (5 alpha R), and androgen receptor (AR; cytosolic) levels were assessed in the brain, heart (HRT), lung (LNG), and skeletal muscle (MUS) of fetal rhesus monkeys. An...

journal_title：Endocrinology

authors： Sholl SA,Goy RW,Kim KL

更新日期：1989-02-01 00:00:00

abstract：:A rare 20K isoform of GH-V (here abbreviated as GHv) was discovered in 1998. To date, only 1 research article has characterized this isoform in vivo, observing that GHv treatment in male high-fat fed rats had several GH-like activities, but unlike GH lacked diabetogenic and lactogenic activities and failed to increase...

journal_title：Endocrinology

authors： List EO,Berryman DE,Basu R,Buchman M,Funk K,Kulkarni P,Duran-Ortiz S,Qian Y,Jensen EA,Young JA,Yildirim G,Yakar S,Kopchick JJ

更新日期：2020-08-01 00:00:00

abstract：:Kisspeptin-neurokinin B-dynorphin (KNDy) cells of the hypothalamus are a key component in the neuroendocrine regulation of GnRH secretion. Evidence in sheep and other species suggests that dynorphin released by KNDy cells inhibits pulsatile GnRH secretion by acting upon κ-opioid receptors (KOR). However, the precise a...

journal_title：Endocrinology

authors： Weems PW,Witty CF,Amstalden M,Coolen LM,Goodman RL,Lehman MN

更新日期：2016-06-01 00:00:00

abstract：:Rat sexual maturation is preceded by a reduction of the interpulse interval (IPI) of GnRH neurosecretion. This work aims at studying disruption of that neuroendocrine event in females after early exposure to a very low dose of bisphenol A (BPA), a ubiquitous endocrine disrupting chemical. Female rats were exposed to v...

journal_title：Endocrinology

authors： Franssen D,Gérard A,Hennuy B,Donneau AF,Bourguignon JP,Parent AS

更新日期：2016-05-01 00:00:00

abstract：:A study was conducted to determine the influence of conditions known to alter ACTH secretion on prolactin release by the pituitary. Dexamethasone or 0.9% NaCl was injected subcutaneously into intact male rats 4 hr before a 2-min ether stress. Other rats were submitted to the ether stress 2 weeks following adrenalectom...

journal_title：Endocrinology

authors： Harms PG,Langlier P,McCann SM

更新日期：1975-02-01 00:00:00

abstract：:In the mouse, there is a large family of paralogous genes closely related to PRL. The objective of this report was to investigate the organization of the mouse PRL gene family locus. PRL family genes reside on chromosome 13 of the mouse genome. The PRL gene family members were localized to a series of overlapping bact...

journal_title：Endocrinology

authors： Wiemers DO,Shao LJ,Ain R,Dai G,Soares MJ

更新日期：2003-01-01 00:00:00

abstract：:The effects of undernutrition on the timing of puberty and regulation of LH secretion by the inhibitory and stimulatory feedback action of estradiol were examined in female sheep. The first experiment determined that maintenance of low BW (ca., 20 kg, four lambs) between 10 and 45 weeks of age prevented initiation of ...

journal_title：Endocrinology

authors： Foster DL,Olster DH

更新日期：1985-01-01 00:00:00

abstract：:Osteoclast precursors reach sites of osteoclast formation and remodelling via the vasculature and are therefore destined to encounter endothelium before migrating to the bone surface. Here we investigated the hypothesis that endothelium may be involved in the regulation of osteoclast precursor recruitment to sites of ...

journal_title：Endocrinology

authors： McGowan NW,Walker EJ,Macpherson H,Ralston SH,Helfrich MH

更新日期：2001-04-01 00:00:00

abstract：:The influence of sex hormones on the immune response to foreign antigens as well as self-antigens is now recognized. In this study, we investigated the influence of gender and sex hormones on the development of antibodies to double-stranded DNA in nonautoimmune C57BL/6J mice. Immunoglobulin G (IgG) anti-dsDNA antibodi...

journal_title：Endocrinology

authors： Verthelyi D,Ahmed SA

更新日期：1994-12-01 00:00:00