Abstract:
:The effect of beta-endorphin upon plasma arg8-vasopressin release was studied in vivo in rabbits and in vitro in rat neural lobes. Following intravenous administration of 200 mug/kg synthetic beta-endorphin plasma AVP rose significantly by five minutes after injection and remained elevated for twenty-five minutes compared to controls. In contrast beta-endorphin had no significant effect on AVP release from isolated rat neural lobes in vitro. beta-Endorphin stimulates AVP secretion in vivo, but this is not due to a direct action upon the neural lobe.
journal_name
Endocrinologyjournal_title
Endocrinologyauthors
Weitzman RE,Fisher DA,Minick S,Ling N,Guillemin Rdoi
10.1210/endo-101-5-1643subject
Has Abstractpub_date
1977-11-01 00:00:00pages
1643-6issue
5eissn
0013-7227issn
1945-7170journal_volume
101pub_type
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