Nonlinearity of spatial summation in simple cells of areas 17 and 18 of cat visual cortex.

Abstract:

:1. Nonlinearity of spatial summation in areas 17 and 18 of cat visual cortex was compared with the type of spatial nonlinearity that differentiates X and Y cells in the lateral geniculate nucleus (LGN) and retina. The comparisons were made to examine to what extent the information from X and Y cells may remain separated in higher visual centers. 2. Responses of simple cells in areas 17 and 18 were recorded while stationary, optimally oriented sinewave gratings were sinusoidally modulated within the receptive field of the cell. Both the spatial frequency and spatial phase of the stimulus were varied. 3. Y cells in the retina and LGN are defined by the presence of a specific form of spatial nonlinearity. When tested with contrast-modulated sinewave gratings of spatial frequencies about three-fold greater than the optimal, their responses are dominated by a frequency-doubled component. The amplitude of the frequency-doubled component is not dependent on the spatial phase of the stimulus. 4. Many simple cells in the cortex showed a form of spatial nonlinearity similar to the defining nonlinearity found in retinal and geniculate Y cells. A frequency-doubled response dominated at spatial frequencies more than threefold greater than the optimal spatial frequency. When this response was present, it was phase independent. 5. More than 50% of the simple cells in area 18 showed the Y-like spatial nonlinearity. Fewer than 10% of the simple cells in area 17 showed the Y-like spatial nonlinearity. 6. The virtual absence of Y-like nonlinearity in area 17 and its relative abundance in area 18 suggest that the functional separation between the parallel X and Y pathways remains distinct within areas 17 and 18 of cat visual cortex.

journal_name

J Neurophysiol

authors

Ferster D,Jagadeesh B

doi

10.1152/jn.1991.66.5.1667

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

1667-79

issue

5

eissn

0022-3077

issn

1522-1598

journal_volume

66

pub_type

杂志文章
  • alpha7 nicotinic acetylcholine receptors on GABAergic interneurons evoke dendritic and somatic inhibition of hippocampal neurons.

    abstract::GABAergic interneurons in the hippocampus express high levels of alpha7 nicotinic acetylcholine receptors, but because of the diverse roles played by hippocampal interneurons, the impact of activation of these receptors on hippocampal output neurons (i.e., CA1 pyramidal cells) is unclear. Activation of hippocampal int...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00316.2001

    authors: Buhler AV,Dunwiddie TV

    更新日期:2002-01-01 00:00:00

  • Role of neurotransmitter receptors in mediating light-evoked responses in retinal interplexiform cells.

    abstract::Interplexiform (IP) cells are a long-neglected group of retinal neurons the function of which is yet to be determined. Anatomical study indicates that IP cells are located in the inner nuclear layer, juxtaposed with the third-order neurons. However, the synaptic transmission of IP cells in the inner retina is poorly u...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00876.2009

    authors: Jiang Z,Shen W

    更新日期:2010-02-01 00:00:00

  • Mechanisms of pattern generation underlying swimming in Tritonia. IV. Gating of central pattern generator.

    abstract::Swimming behavior in the marine mollusc Tritonia diomedea is episodic, consisting of a series of alternating dorsal and ventral flexions initiated by a brief sensory stimulus. The swim motor pattern is generated by a network formed of four groups of premotor interneurons: cerebral cell 2 (C2), dorsal swim interneurons...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1985.53.2.466

    authors: Getting PA,Dekin MS

    更新日期:1985-02-01 00:00:00

  • Perisaccadic mislocalization of visual targets by head-free gaze shifts: visual or motor?

    abstract::Such perisaccadic mislocalization is maximal in the direction of the saccade and varies systematically with the target-saccade onset delay. We have recently shown that under head-fixed conditions perisaccadic errors do not follow the quantitative predictions of current visuomotor models that explain these mislocalizat...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.90276.2008

    authors: van Wetter SM,van Opstal AJ

    更新日期:2008-10-01 00:00:00

  • Segregated and integrated coding of reward and punishment in the cingulate cortex.

    abstract::Reward and punishment have opposite affective value but are both processed by the cingulate cortex. However, it is unclear whether the positive and negative affective values of monetary reward and punishment are processed by separate or common subregions of the cingulate cortex. We performed a functional magnetic reso...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.90909.2008

    authors: Fujiwara J,Tobler PN,Taira M,Iijima T,Tsutsui K

    更新日期:2009-06-01 00:00:00

  • Development, form, and function of the mouse visual thalamus.

    abstract::The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the exclusive relay of retinal information en route to the visual cortex. Although much of our understanding about dLGN comes from studies done in higher mammals, such as the cat and primate, the mouse as a model organism has moved to the forefront as a t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章,评审

    doi:10.1152/jn.00651.2017

    authors: Guido W

    更新日期:2018-07-01 00:00:00

  • Coincidence detection in pyramidal neurons is tuned by their dendritic branching pattern.

    abstract::Neurons display a variety of complex dendritic morphologies even within the same class. We examined the relationship between dendritic arborization and the coupling between somatic and dendritic action potential (AP) initiation sites in layer 5 (L5) neocortical pyramidal neurons. Coupling was defined as the relative r...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00046.2003

    authors: Schaefer AT,Larkum ME,Sakmann B,Roth A

    更新日期:2003-06-01 00:00:00

  • Modeling neural mechanisms for genesis of respiratory rhythm and pattern. I. Models of respiratory neurons.

    abstract::The general objectives of our research, presented in this series of papers, were to develop a computational model of the brain stem respiratory neural network and to explore possible neural mechanisms that provide the genesis of respiratory oscillations and the specific firing patterns of respiratory neurons. The pres...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.77.4.1994

    authors: Rybak IA,Paton JF,Schwaber JS

    更新日期:1997-04-01 00:00:00

  • Active force perception depends on cerebellar function.

    abstract::Damage to the cerebellum causes characteristic movement abnormalities but is thought to have minimal impact on somatosensory perception. Traditional clinical assessments of patients with cerebellar lesions reveal no perceptual deficits despite the fact that the cerebellum receives substantial somatosensory information...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00983.2011

    authors: Bhanpuri NH,Okamura AM,Bastian AJ

    更新日期:2012-03-01 00:00:00

  • Extra force from asynchronous stimulation of cat soleus muscle results from minimizing the stretch of the common elastic elements.

    abstract::Rack and Westbury showed that low-frequency asynchronous stimulation of a muscle produces greater force compared with synchronous stimulation. This study tested the hypothesis that the difference results from the dynamic stretch of the common elastic elements. In eight anesthetized cats, the soleus was attached to a s...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.01304.2005

    authors: Sandercock TG

    更新日期:2006-09-01 00:00:00

  • Early and late beta-band power reflect audiovisual perception in the McGurk illusion.

    abstract::The McGurk illusion is a prominent example of audiovisual speech perception and the influence that visual stimuli can have on auditory perception. In this illusion, a visual speech stimulus influences the perception of an incongruent auditory stimulus, resulting in a fused novel percept. In this high-density electroen...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00783.2014

    authors: Roa Romero Y,Senkowski D,Keil J

    更新日期:2015-04-01 00:00:00

  • Whisker trimming begun at birth or on postnatal day 12 affects excitatory and inhibitory receptive fields of layer IV barrel neurons.

    abstract::In rats, whisker trimming during development leads to persistent alterations in the function of cortical barrel circuits and to behavioral deficits later in life. Here we examined how whisker trimming begun either at birth (P0) or on postnatal day 12 (P12), around the onset of whisking behavior, affects receptive fiel...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00569.2005

    authors: Shoykhet M,Land PW,Simons DJ

    更新日期:2005-12-01 00:00:00

  • Varying the degree of single-whisker stimulation differentially affects phases of intrinsic signals in rat barrel cortex.

    abstract::Using intrinsic signal optical imaging (ISI), we have shown previously that the point spread of evoked activity in the rat barrel cortex in response to single-whisker stimulation encompasses a surprisingly large area. Given that our typical stimulation consists of five deflections at 5 Hz, the large area of evoked act...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1999.81.2.692

    authors: Polley DB,Chen-Bee CH,Frostig RD

    更新日期:1999-02-01 00:00:00

  • Local tuning biases in mouse primary visual cortex.

    abstract::Neurons in primary visual cortex are selective to the orientation and spatial frequency of sinusoidal gratings. In the classic model of cortical organization, a population of neurons responding to the same region of the visual field but tuned to all possible feature combinations provides a detailed representation of t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00150.2018

    authors: Jimenez LO,Tring E,Trachtenberg JT,Ringach DL

    更新日期:2018-07-01 00:00:00

  • Differential effects of tetanus toxin on inhibitory and excitatory synaptic transmission in mammalian spinal cord neurons in culture: a presynaptic locus of action for tetanus toxin.

    abstract::Tetanus toxin reduces monosynaptic inhibitory and excitatory synaptic transmission in mouse spinal cord neurons in culture. Inhibitory transmission is preferentially reduced by the toxin; however, excitatory transmission is also ultimately reduced and blocked by the concentrations of toxin used in these studies. Recor...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.57.1.121

    authors: Bergey GK,Bigalke H,Nelson PG

    更新日期:1987-01-01 00:00:00

  • Mechanisms for shaping receptive field in monkey area TE.

    abstract::Visual object information is conveyed from V1 to area TE along the ventral visual pathway with increasing receptive field (RF) sizes. The RFs of TE neurons are known to be large, but it is largely unknown how large RFs are shaped along the ventral visual pathway. In this study, we addressed this question in two aspect...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00348.2017

    authors: Obara K,O'Hashi K,Tanifuji M

    更新日期:2017-10-01 00:00:00

  • Neural mechanisms for predictive head movement strategies during sequential gaze shifts.

    abstract::Humans adopt very different head movement strategies for different gaze behaviors, for example, when playing sports versus watching sports on television. Such strategy switching appears to depend on both context and expectation of future gaze positions. Here, we explored the neural mechanisms for such behaviors by tra...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00222.2012

    authors: Monteon JA,Avillac M,Yan X,Wang H,Crawford JD

    更新日期:2012-11-01 00:00:00

  • Case studies in neuroscience: subcortical origins of the frequency-following response.

    abstract::The auditory frequency-following response (FFR) reflects synchronized and phase-locked activity along the auditory pathway in response to sound. Although FFRs were historically thought to reflect subcortical activity, recent evidence suggests an auditory cortex contribution as well. Here we present electrophysiologica...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00112.2019

    authors: White-Schwoch T,Anderson S,Krizman J,Nicol T,Kraus N

    更新日期:2019-08-01 00:00:00

  • Sherlock Holmes and the curious case of the human locomotor central pattern generator.

    abstract::Evidence first described in reduced animal models over 100 years ago led to deductions about the control of locomotion through spinal locomotor central pattern-generating (CPG) networks. These discoveries in nature were contemporaneous with another form of deductive reasoning found in popular culture, that of Arthur C...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章,评审

    doi:10.1152/jn.00554.2017

    authors: Klarner T,Zehr EP

    更新日期:2018-07-01 00:00:00

  • Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity.

    abstract::We have investigated potential mechanisms by which exercise can promote changes in neuronal plasticity via modulation of neurotrophins. Rodents were exposed to voluntary wheel running for 3 or 7 days, and their lumbar spinal cord and soleus muscle were assessed for changes in brain-derived neurotrophic factor (BDNF), ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00152.2002

    authors: Gómez-Pinilla F,Ying Z,Roy RR,Molteni R,Edgerton VR

    更新日期:2002-11-01 00:00:00

  • Global electrosensory oscillations enhance directional responses of midbrain neurons in eigenmannia.

    abstract::Eigenmannia, a genus of weakly electric fish, exhibits a specialized behavior known as the jamming avoidance response (JAR). The JAR results in a categorical difference between Eigenmannia that are in groups of conspecifics and those that are alone. Fish in groups exhibit the JAR behavior and thereby experience ongoin...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00311.2006

    authors: Ramcharitar JU,Tan EW,Fortune ES

    更新日期:2006-11-01 00:00:00

  • Signal transmission in the catfish retina. IV. Transmission to ganglion cells.

    abstract::1. To characterize the temporal dynamic responses of ganglion cells and to define the possible inputs giving rise to their responses in catfish retina, we recorded the ganglion cell responses evoked by 1) a step of light presented in the dark, 2) an incremental and decremental step from a background illumination, and ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.58.6.1307

    authors: Sakai HM,Naka K

    更新日期:1987-12-01 00:00:00

  • Variation in serotonergic inhibition of calcium channel currents in four types of rat sensory neurons differentiated by membrane properties.

    abstract::1. Rat dorsal root ganglion (DRG) cell bodies were screened according to action potential (AP) duration, capsaicin sensitivity, expression of IH, IA, and N-, L-, and T-type Ca2+ channel currents. AP duration was measured at half of total amplitude at a membrane potential of -60 mV. Sensitivity to capsaicin was defined...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1995.74.5.1870

    authors: Cardenas CG,Del Mar LP,Scroggs RS

    更新日期:1995-11-01 00:00:00

  • L-arginine via nitric oxide is an inhibitory feedback modulator of Aplysia feeding.

    abstract::An increase in L-arginine hemolymph concentration acts as a postingestion signal inhibiting Aplysia feeding. At physiological concentrations (a 10-μM increase over background), the inhibitory effect of L-arginine is too weak to block feeding in hungry animals. However, a 10-μM increase in L-arginine concentration acts...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00827.2010

    authors: Miller N,Saada R,Markovich S,Hurwitz I,Susswein AJ

    更新日期:2011-04-01 00:00:00

  • Neural responses elicited by stimuli associated with masking of low-frequency, monaural tonal signals by noise.

    abstract::The responses of low-frequency, primary-like neurons of the ventral cochlear nucleus were measured as a function of signal-to-noise ratio for gated tonal signals and noise maskers that were varied in bandwidth and duration. For a given signal-to-noise ratio, each of the maskers is known to produce the same amount of m...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1983.50.6.1516

    authors: Langford TL

    更新日期:1983-12-01 00:00:00

  • Spatiotemporal distribution of location and object effects in reach-to-grasp kinematics.

    abstract::In reaching to grasp an object, the arm transports the hand to the intended location as the hand shapes to grasp the object. Prior studies that tracked arm endpoint and grip aperture have shown that reaching and grasping, while proceeding in parallel, are interdependent to some degree. Other studies of reaching and gr...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.00686.2015

    authors: Rouse AG,Schieber MH

    更新日期:2015-12-01 00:00:00

  • Central peptidergic neurons regulate gut motility in Aplysia.

    abstract::1. The small cardioactive peptides (SCPs) are potent modulatory neuropeptides in Aplysia. Buccal ganglia neurons B1 and B2 are the largest neurons that exhibit SCP-like immunoreactivity. High-pressure liquid chromatography (HPLC)-bioassay and in vivo radiolabeling procedures confirm that these neurons contain and synt...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.5.1613

    authors: Lloyd PE,Kupfermann I,Weiss KR

    更新日期:1988-05-01 00:00:00

  • Natural groupings of primate spinothalamic neurons based on cutaneous stimulation. Physiological and anatomical features.

    abstract::1. Two hundred and twenty-one spinothalamic tract (STT) neurons in the lumbar spinal cord of anesthetized monkeys were studied. The majority of the recordings were in laminae IV-VI. Thirteen of these neurons were intracellularly injected with horseradish peroxidase and histologically reconstructed. 2. A standard serie...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.3.833

    authors: Surmeier DJ,Honda CN,Willis WD Jr

    更新日期:1988-03-01 00:00:00

  • Modulatory actions of serotonin, norepinephrine, dopamine, and acetylcholine in spinal cord deep dorsal horn neurons.

    abstract::The deep dorsal horn represents a major site for the integration of spinal sensory information. The bulbospinal monoamine transmitters, released from serotonergic, noradrenergic, and dopaminergic systems, exert modulatory control over spinal sensory systems as does acetylcholine, an intrinsic spinal cord biogenic amin...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.2001.86.5.2183

    authors: Garraway SM,Hochman S

    更新日期:2001-11-01 00:00:00

  • Mechanisms of onset responses in octopus cells of the cochlear nucleus: implications of a model.

    abstract::The octopus cells of the posteroventral cochlear nucleus receive inputs from auditory-nerve fibers and form one of the major ascending auditory pathways. They respond to acoustic and electrical stimulation transiently and are believed to carry temporal information in the precise timing of their action potentials. The ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1997.78.2.872

    authors: Cai Y,Walsh EJ,McGee J

    更新日期:1997-08-01 00:00:00