Abstract：
:2-Cys peroxiredoxins (PRDX) are novel antioxidant enzymes that eliminate the hydrogen peroxide in cells to protect the cellular components from reactive oxygen species. To evaluate whether 2-Cys PRDX family plays a role in human ciliary body, the expression of PRDX I, II and III on normal human ciliary body was investigated. Three normal human ciliary body tissues obtained from three donor eyeballs were examined by an immunohistochemistry using light microscopy and fluorescent microscopy with antibodies directed against the PRDX I, II and III. In the normal human ciliary body, PRDX I, II and III were immunolocalized to the non-pigmented epithelial cells and ciliary muscle fibers. It suggests that 2-Cys PRDXs may have physiological functions to protect cells in human ciliary body.
journal_name
Tissue Celljournal_title
Tissue & cellauthors
Hong S,Kim CY,Lee JH,Seong GJdoi
10.1016/j.tice.2007.06.003subject
Has Abstractpub_date
2007-10-01 00:00:00pages
365-8issue
5eissn
0040-8166issn
1532-3072pii
S0040-8166(07)00055-9journal_volume
39pub_type
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