Abstract:
:Until primate sperm are exposed to the unique microenvironment of the epididymis, they are not capable of fertilization or vigorous motility. Many of the proteins that contribute to the unique microenvironment of the primate epididymis, and thus to sperm maturation, are dependent on androgens to induce their synthesis and secretion. GnRH antagonists have proved effective in suppressing LH and testosterone synthesis and secretion, and thus in maintaining a state of androgen deprivation or functional hypogonadotropism. We report here the effects of GnRH antagonist-induced androgen-deprivation on the histology of the testicular interstitium and seminiferous epithelium of the adult male chimpanzee. After only 21 days of androgen-deprivation, chimpanzee testicular tissues exhibit specific atrophic changes, including the loss of contact between developing spermatocytes and between Sertoli cells and their developing spermatids, alterations in cell development resulting in missing maturation steps (elongating Sc and structurally complete Sd2 spermatids) and inappropriate cell associations, varying degrees of cytoplasmic degradation in germ cells, Sertoli cells, and Leydig cells, and a tubular lumen obscured by masses of sloughed primary and secondary spermatocytes and what appear histologically to be Sb1 and Sd1 spermatids.
journal_name
Tissue Celljournal_title
Tissue & cellauthors
Smithwick EB,Young LGdoi
10.1054/tice.2000.0164subject
Has Abstractpub_date
2001-06-01 00:00:00pages
262-72issue
3eissn
0040-8166issn
1532-3072pii
S0040816600901642journal_volume
33pub_type
杂志文章相关文献
TISSUE & CELL文献大全abstract::The females of some species of the family Halophilosciidae receive in the course of mating a quantity of sperm considerably redundant with respect to the number of eggs that can be fertilized; this is possible thanks to the peculiar morpho-functional organization that characterizes their genital system and that allows...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2014.05.007
更新日期:2014-08-01 00:00:00
abstract::Sporogony of the sporozoan Theileria parva in the salivary gland of the tick vector of East Coast fever was studied in electron micrographs. The findings differ in several respects from previous interpretations based upon light microscopy. Cytokinesis of the primary sporoblast to form secondary and tertiary sporoblast...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(82)90017-9
更新日期:1982-01-01 00:00:00
abstract::Reptilian epidermis contains two types of keratin, soft (alpha) and hard (beta). The biosynthesis and molecular weight of beta-keratin during differentiation of lizard epidermis have been studied by autoradiography, immunocytochemistry and immunoblotting. Tritiated proline is mainly incorporated into differentiating a...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2004.06.001
更新日期:2004-10-01 00:00:00
abstract::The fine structure of the principal and ancillary metathoracic flight muscle fibres in the adult male of a strepsipteran, Elenchus tenuicornis, is described. Power-producing dorsal longitudinal and dorso-ventral flight muscles show features consistent with myoneural asynchrony: myofibrils are large and discrete and ar...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(84)90072-7
更新日期:1984-01-01 00:00:00
abstract::Lenticles are dome-shaped circles or ovals of cuticle with a dark rim. They occur with a precise segmental arrangement in the larvae and pupae of lycaenid and hesperiid butterflies. In Calpodes ethlius (Lepidoptera, Hesperiidae) each lenticle is secreted by a pair of large polyploid epidermal cells. The dark rim or an...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(84)90048-x
更新日期:1984-01-01 00:00:00
abstract::Annulate lamellae have been found in a primitive neuroectodermal tumor, a metastatic cerebellar tumor, a testicular seminoma, a retinoblastoma and three melanomas. These annulate lamellae are arranged in stacked parallel arrays in the cytoplasm of tumor cells. The number of annulate lamellae observed to comprise a sin...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(79)90014-4
更新日期:1979-01-01 00:00:00
abstract::An intestinal epithelial cell line (IEC-17), undergoing a process of progressive morphological differentiation, was analysed for expression and synthesis of the extracellular matrix glycoproteins, fibronectin (FN) and laminin (LM). FN and LM cell surface expression was detected by immunoelectron microscopy, while intr...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(88)90066-3
更新日期:1988-01-01 00:00:00
abstract::Nuclei in the giant polyploid silk gland cells of Calpodes ethlius grow by endomitosis and can develop hundreds of branches during larval life. The shape of the these nuclei is characteristic for each region of the gland. We have found shape to be correlated with arrangement of the nuclear matrix. Scanning electron mi...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(91)90036-s
更新日期:1991-01-01 00:00:00
abstract::The sensory organs on the tarsi of the antenniform first legs of the whip spider Admetus pumilio C. L. Koch (Amblypygi, Arachnida) were examined with the scanning and transmission electron microscope. At least four different types of hair sensilla were found: (1) thick-walled bristles, which have the characteristics o...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(75)90009-9
更新日期:1975-01-01 00:00:00
abstract::A morphological and ultrastructural study was carried out on the spermatophore and spermatodoses of some species of Orthoptera Tettigoniidae. From the results concerning the spermatophore it emerged that this structure has a morphological and ultrastructural organization represented by a dilated ampulla and a peduncle...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040816602000344
更新日期:2002-10-01 00:00:00
abstract::The guppy is a tropical fish that has been used as an experimental model organism in science. It is a species well adapted to the natural environment and that can support adverse environmental conditions, and so, at occasions, its presence can be indicative of environmental disturbances. Moreover, as the liver is very...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2017.12.009
更新日期:2018-02-01 00:00:00
abstract::This study is designed to better understand the function of the Müller cells of the retina through the use of silicon particles that had been injected into the vitreous body of the eye and via an analysis of the number of gap junctions associated with these cells. Following intraocular injection of a silicone oil mixt...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(93)90028-j
更新日期:1993-01-01 00:00:00
abstract::Bovine pulmonary artery endothelial cells in culture were evaluated by phase-contrast and electron microscopy at various times after being irradiated with 137Cs in vitro. Cells irradiated prior to reaching confluency showed vacuolization aand increased numbers of lysosomes beginning at 48 hr after irradiation with 300...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(83)90016-2
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Mesenchymal stem cells (MSCs) are currently the most promising candidates in regenerative medicine. Nonetheless, there are several limitations associated with the MSC tissue source such as infrequent and invasive bone marrow sampling methods. To overcome these limitations, we have procured MSCs from the mens...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2018.09.010
更新日期:2018-12-01 00:00:00
abstract::As a defensive reaction against predators the larvae of Zygaena trifolii Esper. 1783, release highly viscous fluid droplets out of cuticular cavities. The fluid appears on the cuticular surface upon contraction of the irritated segments, with no specialized muscles being involved. Two morphologically different types o...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(85)90093-x
更新日期:1985-01-01 00:00:00
abstract::This report describes a technique which permits a high yield of viable adult cardiac myocytes from the adult newt using enzymatic separation techniques at low temperature and high enzyme concentrations. Observations by light microscopy showed the isolated myocytes to have a distinctively slender morphology which consi...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(87)90049-8
更新日期:1987-01-01 00:00:00
abstract::The Piau boar is a rustic breed of economical importance in Brazil. The duration of spermatogenesis and sperm transit through the epididymis in Piau boars was estimated using intratesticular injections of tritiated thymidine. Animals were sacrificed 1 h, 7 days, 14 days, 21 days, 34 days, and 36 days after injections....
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(98)80038-4
更新日期:1998-10-01 00:00:00
abstract::Cellular replacement therapy is a potential therapeutic strategy for diabetes. In this study, we investigated the effect of transplantation of induced mouse embryonic stem cells (mESCs) into endoderm and early hepatocyte-like cells in streptozotocin (STZ)-diabetic mice. After embryoid body (EB) formation from mESC, th...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2010.12.002
更新日期:2011-04-01 00:00:00
abstract::Experiments in vitro have shown that 20-hydroxyecdysone (at a concentration of 0.2 and 2 microM and after 12 and 24 hr of incubation) is able to induce the precocious deposition of chorion materials by the follicular epithelium of young oocytes of the cockroach Blattella germanica. Since previous studies had shown tha...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(93)90019-h
更新日期:1993-04-01 00:00:00
abstract::Acute spinal cord injuries (ASCI) are common neural disorders in traumatology medicine. MicroRNA-210 (miR-210) plays a crucial role in cell survival, endothelial cell migration and cell regeneration. This paper is aim to validate the pathophysiological function of miR-210 on ASCI. We built a rat model of ASCI and util...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2019.02.004
更新日期:2019-04-01 00:00:00
abstract::Head and neck cancers are common in several regions of the world and the treatment usually includes radiotherapy. This treatment can generate adverse effects to the salivary flow, with a relationship between the dose and the damage caused. Salivary gland cells are highly permeable to water and therefore, they express ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2018.06.006
更新日期:2018-08-01 00:00:00
abstract::Enzymatically dissociated hamster tracheal epithelial (HTE) cells were cultured on collagen coated Millicell filters. Within 3-5 days after being placed in culture large numbers of ciliated and mucus cells began to appear. By 1 week the HTE cells closely resembled those seen in vivo, i.e. columnar morphology and organ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(87)90019-x
更新日期:1987-01-01 00:00:00
abstract::The skin of hairless descendants of Mexican hairless dogs was investigated lectin-histochemically. Haired dogs were also used for comparative study. In the epidermis of infant pups, lectin staining revealed marked differences between hairless and haired dogs. Griffonia simplicifolia-I (GS-I) bound moderately to the cy...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/0040-8166(94)90080-9
更新日期:1994-02-01 00:00:00
abstract::The seasonal variations in serotonin immunoreactivity and ultrastructure of the secretory rudimentary photoreceptor cells (SRPC) were studied in the pineal organ of the Japanese grass lizard, Takydromus tachydromoides in relation to the environmental temperature. Our results clearly demonstrated that serotonin immunor...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.1999.0054
更新日期:1999-08-01 00:00:00
abstract::The Malpighian tubules of adult flesh fly, Sarcophaga ruficornis consist of principal and stellate cells. The principal cells reveal all the characteristics of transporting epithelia with well developed deep basal membrane infoldings forming a complex of interconnecting labyrinth of canaliculi and luminal microvilli, ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2013.04.002
更新日期:2013-10-01 00:00:00
abstract::The expression and localization of gap junctional proteins connexin (Cx) 26, 32, and 43 was examined in human dental pulp. Dental pulp tissues were obtained from human third molars immediately after extraction. Some pulp tissues were used for cell culture, and the rest for histological observations. Immunostaining for...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(02)00028-9
更新日期:2002-06-01 00:00:00
abstract::Spermatozoa and spermiogenesis of the prithine filistatid spider Wandella orana are described. The spider produces coenospermia, i.e. sperm aggregations that include several single sperm cells commonly surrounded by a secretion sheath. One sectioned coenospermium in W. orana contains at least five spermatozoa. During ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(03)00054-5
更新日期:2003-10-01 00:00:00
abstract::Pyridoxal-5'-phosphate, the active form of vitamin B6, is associated with activities of several enzymes and the treatment of various neurological disorders. Here, we investigated the effects of pyridoxine on the immunoreactivity and protein levels of γ-aminobutyric acid (GABA)-synthesizing and degradation enzymes such...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2019.09.005
更新日期:2019-12-01 00:00:00
abstract::The paired ovaries of young larva of the 3rd instar of Orthezia urticae are filled with numerous germ cell clusters that can be regarded as ovariole anlagen. Germ cells (cystocytes) belonging to one cluster form a rosette, in the centre of which a polyfusome occurs. Staining with rhodamine-phalloidin has revealed that...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(97)80069-9
更新日期:1997-02-01 00:00:00
abstract::We have recently shown that down-regulation of mouse Thy28 (mThy28) protein expression appears to be accompanied by apoptotic processes. Thymocytes from mice contain moderate amounts of mThy28 protein and undergo proliferation, differentiation, or apoptosis during murine thymic maturation. As a first step to examine t...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(03)00073-9
更新日期:2003-12-01 00:00:00