Alzheimer lesions in the entorhinal region and isocortex in Parkinson's and Alzheimer's diseases.

abstract：:Multiple sclerosis (MS) is an autoimmune and chronic inflammatory disease characterized by plaques, areas of destroyed myelin sheaths in the CNS, which results in multiple disabilities for patients. In addition to demyelinated plaques, pathophysiological studies have shown "shadow plaques" that represent areas of part...

journal_title：Annals of the New York Academy of Sciences

authors： Filipović R,Zecević N

更新日期：2005-06-01 00:00:00

abstract：:Decreased postural stability is observed in most astronauts immediately following spaceflight. Because ataxia may present postflight operational hazards, it is important to determine the incidence of postural instability immediately following landing and the dynamics of recovery of normal postural equilibrium control....

journal_title：Annals of the New York Academy of Sciences

authors： Paloski WH,Reschke MF,Black FO,Doxey DD,Harm DL

更新日期：1992-05-22 00:00:00

abstract：:Image processing in fluid mechanics has become an important quantitative tool for flow analysis. The feasibility of simultaneous measurements of instantaneous velocity and temperature fields, as well as for tracking interfaces, creates a functional tool to describe thermally driven flows accompanied by phase change. T...

journal_title：Annals of the New York Academy of Sciences

authors： Kowalewski TA

更新日期：2002-10-01 00:00:00

abstract：:There is an urgent need for surrogate biomarkers in clinical diagnostics but also preclinical in toxicology of chemicals and efficacy testing of pharmaceuticals. On the background of the emerging fields of systems biology and theranostics, the importance of time scales and the synchronization of complex biological rea...

journal_title：Annals of the New York Academy of Sciences

authors： Schrattenholz A,Soskić V,Groebe K

更新日期：2010-06-01 00:00:00

abstract：:Asbestos contamination of relatively contained environments within structures can occur under many conditions and in association with various activities. Such contamination persists and can potentially expose all structure users. The more significant contamination levels are associated with disturbance of friable asbe...

journal_title：Annals of the New York Academy of Sciences

authors： Sawyer RN

更新日期：1979-01-01 00:00:00

abstract：:The public health implications of reducing or preventing the excess increase in blood pressure and the acquisition of obesity during childhood years are important. Many children with high blood pressure, particularly those who are initially obese or become obese as young adults and those with excess left ventricular m...

journal_title：Annals of the New York Academy of Sciences

authors： Mahoney LT,Lauer RM,Lee J,Clarke WR

更新日期：1991-01-01 00:00:00

abstract：:The role of dopaminergic activity in susceptibility of methamphetamine (MAP) psychosis (flashbacks) to subsequent spontaneous recurrences was studied. Plasma monoamine metabolite levels were assayed in 23 flashbackers, of whom 10 experienced a single flashback, 8 exhibited subsequent flashbacks and 5 with the last epi...

journal_title：Annals of the New York Academy of Sciences

authors： Yui K,Goto K,Ikemoto S

更新日期：2004-10-01 00:00:00

abstract：:We have studied the conductance of molecular films as a function of orientation of the molecules in the film with respect to electrodes. Depending on the angle between the axis of the molecules and the normal to the electrode, the conductance may change by more than an order of magnitude. This is a consequence of the ...

journal_title：Annals of the New York Academy of Sciences

authors： Kornilovitch PE,Bratkovsky AM

更新日期：2002-04-01 00:00:00

abstract：:Replicative senescence is an in vitro biological phenomenon that results the irreversible growth arrest of mammalian cells. In contrast, cellular quiescence is reversible upon the addition of mitogens or replating. Quiescence is associated with the expression of a particular gene family--the growth arrest specific (GA...

journal_title：Annals of the New York Academy of Sciences

authors： Gonos ES

更新日期：1998-06-30 00:00:00

abstract：:Odorant receptors are thought to be critical determinants of olfactory sensory neuron axon targeting and organization. Nonetheless, a systematic characterization of the onset of odorant receptor expression has not yet been done in the main olfactory epithelium. Here, we briefly review our current understanding regardi...

journal_title：Annals of the New York Academy of Sciences

authors： Rodriguez-Gil DJ,Treloar HB,Miller A,Two A,Iwema C,Greer CA

更新日期：2009-07-01 00:00:00

abstract：:Methamphetamine (METH) is a major drug of abuse in the United States. A high dose of METH given to mice and rats causes long-lasting depletion of tyrosine hydroxylase activity, dopamine (DA), and DA-transporter (DAT) binding sites in the striatum. In human METH-abusers, a marked decrease of the DAT in the caudate puta...

journal_title：Annals of the New York Academy of Sciences

authors： Itzhak Y,Ali SF

更新日期：2002-06-01 00:00:00

abstract：:tRNA prepared from cells of E. coli B that had been incubated with 0.5% DL-ethionine (Ethio sRNA) was found to accept methyl groups from 14CH3-S-adenosyl-methionine in the enzymatic reaction catalyzed in vitro by tRNA methyl transferases from untreated cells of the same organism. tRNA from cells that were not exposed ...

journal_title：Annals of the New York Academy of Sciences

authors： Wainfan E,Maschio FA

更新日期：1975-08-08 00:00:00

abstract：:Pregnancy rates among adolescents have not decreased over the last 10 years, despite numerous efforts. To solve this important health problem, the major strategy recommended is to encourage contraceptive use among sexually active teenagers. An important means of obtaining this is by promoting methods that are not depe...

journal_title：Annals of the New York Academy of Sciences

authors： Wildemeersch D,Van Kets H,Vrijens M,Delbarge W,Van Trappen Y,Temmerman M,Depypere H,Thiery M

更新日期：1997-06-17 00:00:00

abstract：:Corticosteroids have potent immunosuppressive and anti-inflammatory effects. Although corticosteroids are an important weapon in the clinical arsenal for treating inflammatory episodes, the mechanisms underlying the actions and regulation of endogenous corticosteroids remain obscure. In the late 1980s and early 1990s,...

journal_title：Annals of the New York Academy of Sciences

authors： Harbuz MS,Chover-Gonzalez AJ,Jessop DS

更新日期：2003-05-01 00:00:00

abstract：:The following on proton pump inhibitors (PPIs) and chemoprevention in relation to Barrett's esophagus includes commentaries on 48-h pH monitoring, pH-impedence, bile acid testing, dyspepsia, long/short segment Barrett's esophagus, nonerosive reflux disease (NERD), functional heartburn, dual-release delivery PPIs, imme...

journal_title：Annals of the New York Academy of Sciences

authors： Richter JE,Penagini R,Tenca A,Pohl D,Dvorak K,Goldman A,Savarino E,Zentilin P,Savarino V,Watson JT,Wong RK,Pace F,Casini V,Peura DA,Herzig SJ,Kamiya T,Pelosini I,Scarpignato C,Armstrong D,DeVault KR,Bechi P,Tadd

更新日期：2011-09-01 00:00:00

abstract：:The interleukin (IL)-2 receptor has proved an attractive target for T cell-directed therapies. Agents including monoclonal antibodies, single-chain antibody immunoconjugates, radioimmunoconjugates, and, most recently, ligand fusion toxins have demonstrated activity in vitro and in clinical trials in both hematologic m...

journal_title：Annals of the New York Academy of Sciences

authors： Foss FM

更新日期：2001-09-01 00:00:00

abstract：:This paper presents a system dynamics policy model of nutritional food market transformation, tracing over-time interactions between the nutritional quality of supply, consumer food choice, population health, and governmental policy. Applied to the Canadian context and with body mass index as the primary outcome, we e...

journal_title：Annals of the New York Academy of Sciences

authors： Struben J,Chan D,Dubé L

更新日期：2014-12-01 00:00:00

abstract：:Long-term repopulating hematopoietic stem cells can be separated from cells which provided radioprotection (short-term repopulating cells) on the basis of size. This might be a result of the quiescent nature of long-term repopulating cells. To define the activity of these populations we utilized a dye, PKH26, which in...

journal_title：Annals of the New York Academy of Sciences

authors： Lanzkron SM,Collector MI,Sharkis SJ

更新日期：1999-04-30 00:00:00

abstract：:Mounting evidence indicates increased susceptibility to cell death and increased oxidative damage as common features in neurons from sporadic Alzheimer's disease (AD) patients but also from familial AD (FAD) cases. Autosomal dominant forms of FAD are caused by mutations of the amyloid precursor protein (APP) gene and ...

journal_title：Annals of the New York Academy of Sciences

authors： Eckert A,Marques CA,Keil U,Schüssel K,Müller WE

更新日期：2003-12-01 00:00:00

abstract：:A brief overview of the different techniques used to estimate the probable maximum precipitation (PMP) is presented. As a particular case, the 1-day PMP over Catalonia has been calculated and mapped with a high spatial resolution. For this purpose, the annual maximum daily rainfall series from 145 pluviometric station...

journal_title：Annals of the New York Academy of Sciences

authors： Casas MC,Rodríguez R,Nieto R,Redaño A

更新日期：2008-12-01 00:00:00

abstract：:Adaptive co-evolution of mammals and bacteria has led to the establishment of complex commensal communities on mucosal surfaces. In spite of having available a wealth of immune-sensing and effector mechanisms capable of triggering inflammation in response to microbial intrusion, mucosal immune cells establish an intim...

journal_title：Annals of the New York Academy of Sciences

authors： Cerutti A,Cols M,Gentile M,Cassis L,Barra CM,He B,Puga I,Chen K

更新日期：2011-11-01 00:00:00

abstract：:The aim of this retrospective study is to assess the frequency of HLA-B27 and HLA-B51 in healthy subjects from the center of Tunisia and to investigate their usefulness in the diagnosis of ankylosing spondylitis (AS) and Behçet's disease (BD), respectively. Microlymphocytotoxicity test was used to perform serologic HL...

journal_title：Annals of the New York Academy of Sciences

authors： Sakly N,Boumiza R,Zrour-Hassen S,Hamzaoui A,Ben Yahia S,Amara H,Khairallah M,Mahjoub S,Bergaoui N,Ghedira I

更新日期：2009-09-01 00:00:00

abstract：:Evidence gathered to date from topographic data, geophysical data, well logs, and drill-core samples indicates that the buried Chicxulub basin, the source crater for the approximately 65 Ma Cretaceous-Tertiary (K/T) boundary deposits, is approximately 300 km in diameter. A prominent topographic ridge and a ring of gra...

journal_title：Annals of the New York Academy of Sciences

authors： Sharpton VL,Marin LE

更新日期：1997-05-30 00:00:00

abstract：:Although very few measurements have appeared in the open literature and there seems to be a controversy about the existence of the NDR phenomenon in molecules, the prospects of building such systems have attracted significant attention. In the work reported in this paper we used a model based on DFT calculations of th...

journal_title：Annals of the New York Academy of Sciences

authors： Simón-Manso Y,Gonzalez C,Mujica V,Aray Y,Marquez M

更新日期：2003-12-01 00:00:00

abstract：:Vestibular stimulation by head accelerations always involves multisensory activation of the vestibular, somatosensory, and visual systems. Over the past few years, galvanic vestibular stimulation (GVS) has become increasingly popular for testing vestibular function for clinical and research purposes. Although GVS prov...

journal_title：Annals of the New York Academy of Sciences

authors： Jahn K,Naessl A,Strupp M,Schneider E,Brandt T,Dieterich M

更新日期：2003-10-01 00:00:00

abstract：:Judicious selection of new animal models for the study of basic aging processes must combine feasibility and good use of the comparative method with evidence of antiaging adaptations, like the ability to combat oxidative damage to cells and tissues. A number of vertebrate species already in use or being developed as n...

journal_title：Annals of the New York Academy of Sciences

authors： Holmes DJ

更新日期：2004-06-01 00:00:00

abstract：:The following study describes the basic demography of colorectal cancer patients and characteristics of the disease seen at a regional tertiary care cancer hospital. The study highlights the influence of gender and age on the occurrence of this malignancy in patients in Pakistan. In general, this population shares man...

journal_title：Annals of the New York Academy of Sciences

authors： Anwar N,Badar F,Yusuf MA

更新日期：2008-09-01 00:00:00

abstract：:Nitric oxide (NO) has been implicated as a mediator of vasodilation and neurotransmission in the mammalian cochlea. This is demonstrated by the presence of nitric oxide synthase (NOS) and nitric oxide (NO) in the blood vessels and the organ of Corti in the cochlea. It is not certain if the neurons in the spiral gangli...

journal_title：Annals of the New York Academy of Sciences

authors： Ruan RS

更新日期：2002-05-01 00:00:00

abstract：:Bacteria can exhibit high levels of resistance to one or more environmental stresses such as temperature, osmolarity, radiation, pH, starvation, as well as resistance to noxious chemicals and antibiotics. Yet evolution has not optimized stress resistance in all bacteria to all stresses. Even within a species like Esch...

journal_title：Annals of the New York Academy of Sciences

authors： Ferenci T,Spira B

更新日期：2007-10-01 00:00:00

abstract：:We studied the role of the peptide substance P, signaling through the neurokinin-1 (NK-1) receptor, on methamphetamine-induced loss of dopamine transporter sites, a well-documented marker of toxicity in the striatum of the mouse brain, because this peptide is under dynamic regulation by the neurotransmitter dopamine. ...

journal_title：Annals of the New York Academy of Sciences

authors： Yu J,Allison S,Ibrahim D,Cadet JL,Angulo JA

更新日期：2002-06-01 00:00:00