Hypothalamo-pituitary-adrenal axis and chronic immune activation.

abstract：:This chapter considers violence prevention programs in light of aggression and violence directed toward girls and women. More specifically, current violence prevention programs, directed toward young children and/or their caregivers, are discussed with a special consideration for the Adults and Children Together (ACT)...

journal_title：Annals of the New York Academy of Sciences

authors： Guttman M,Mowder B,Yasik A

更新日期：2006-11-01 00:00:00

abstract：:To examine whether treatment with cardiopulmonary bypass (CPB), which causes transient cellular immunity depression, influences tuberculin skin testing (TST) interpretation. The study was also aimed to assess the degree of cellular immunity depression following open heart surgery. Fifteen children from developing coun...

journal_title：Annals of the New York Academy of Sciences

authors： Stein M,Sela-Razon B,Linder I,Somekh E

更新日期：2007-08-01 00:00:00

abstract：:The issues of temporal coding and the temporal organization of activity have aroused a great deal of interest in sensory systems, cortex, thalamus, and hippocampus. Strangely, despite the important timing roles attributed to the cerebellum, little consideration has been given to the organization of activity within the...

journal_title：Annals of the New York Academy of Sciences

authors： Isope P,Dieudonné S,Barbour B

更新日期：2002-12-01 00:00:00

abstract：:Lymphotoxin is a protein with a MW of 45,000 daltons derived from activated lymphocytes that kills target cells nonspecifically. Kinetic studies indicate that there is a lag period of about 4 hours before cytotoxicity becomes apparent, even at high concentrations of lymphotoxin. Therefore, the role of lymphotoxin in c...

journal_title：Annals of the New York Academy of Sciences

authors： Mayer MM,Gately MK,Okamoto M,Shin ML,Willoughby JB

更新日期：1979-01-01 00:00:00

abstract：:We have shown that the medial preoptic area (MPO) in the hypothalamus is a major site where interferon (IFN)-alpha acts to induce suppression of splenic natural killer (NK) cell activity through an activation of sympathetic nervous system (SNS) in rats. Here, we discuss the hypothalamic mechanisms of the cytokine acti...

journal_title：Annals of the New York Academy of Sciences

authors： Katafuchi T,Duan S,Take S,Yoshimura M

更新日期：2009-02-01 00:00:00

abstract：:Most measurement devices for bioimpedance spectroscopy are coupled to the measured object (tissue) via electrodes. At frequencies > 500 kHz, they suffer from artifacts due to stray capacitances between electrode leads as well as between the ground and object. The noninvasive measurement of the brain conductivity is ha...

journal_title：Annals of the New York Academy of Sciences

authors： Scharfetter H,Ninaus W,Puswald B,Petrova GI,Kovachev D,Hutten H

更新日期：1999-04-20 00:00:00

abstract：:To study the role of the LDL receptor pathway for the maintenance of alpha-tocopherol concentrations in tissues of intact animals, we have compared vitamin E levels in plasma and tissues of normal rabbits and WHHL rabbits. WHHL rabbits are deficient in LDL receptor activity. For WHHL rabbits, alpha-tocopherol plasma c...

journal_title：Annals of the New York Academy of Sciences

authors： Cohn W,Kuhn H

更新日期：1989-01-01 00:00:00

abstract：:Deposition of amyloid beta protein in the brain is the major pathological feature of Alzheimer's disease. Amyloid beta protein is generated from beta-amyloid precursor protein by beta-secretase and gamma-secretase. Proteolytic processing of amyloid precursor protein at the beta site by BACE1 is essential to generate a...

journal_title：Annals of the New York Academy of Sciences

authors： Zhou W,Qing H,Tong Y,Song W

更新日期：2004-12-01 00:00:00

abstract：:The formation of bone is a continual process in vertebrate development, initiated during fetal development and persisting in adulthood in the form of remodeling and repair. The remarkable capacity of skeletal tissues to regenerate has led to the hypothesis that the molecular signaling pathways regulating skeletogenesi...

journal_title：Annals of the New York Academy of Sciences

authors： Ferguson CM,Miclau T,Hu D,Alpern E,Helms JA

更新日期：1998-10-23 00:00:00

abstract：:The quantitative analysis of nerve growth dynamics is critical to our understanding of nerve development and regeneration, but only recently has a quantitative framework begun to emerge to help define key objectives and to direct experimental measurements towards achieving this goal. Conceptually, the framework center...

journal_title：Annals of the New York Academy of Sciences

authors： Buettner HM

更新日期：1994-11-30 00:00:00

abstract：:The newborn's immune system grows fast from a small size at birth by exposure primarily to the intestinal microflora normally obtained from the mother at and after birth. While building up its immune system, the infant is supported by the transplacental IgG antibodies, which also contain anti-idiotypic antibodies, pos...

journal_title：Annals of the New York Academy of Sciences

authors： Hanson LA,Korotkova M,Lundin S,Håversen L,Silfverdal SA,Mattsby-Baltzer I,Strandvik B,Telemo E

更新日期：2003-04-01 00:00:00

abstract：:Fifty-eight contributors from 12 European and 2 American sarcoidosis centers have collaborated in a survey to define many questions concerning the use of 67Ga lung scan in sarcoidosis. The new quantitative scoring methods based on digital evaluation seem better in detecting lung activity. In 20.1% of untreated patient...

journal_title：Annals of the New York Academy of Sciences

authors： Rizzato G,Blasi A

更新日期：1986-01-01 00:00:00

abstract：:Gene therapy for beta-globinopathies, particularly beta-thalassemia and sickle cell anemia, hold much promise for the future, as a one time cure for these common and debilitating disorders. Correction of the beta-globinopathies using lentivirus vectors (LV) carrying the beta- or gamma-globin genes and elements of the ...

journal_title：Annals of the New York Academy of Sciences

authors： Perumbeti A,Malik P

更新日期：2010-08-01 00:00:00

abstract：:Left ventricular (LV) wall motion abnormalities reflect regional nonuniform contraction which may be arrhythmogenic. We studied sarcomere mechanics and force development (F) in uniform and nonuniform trabeculae using a model in which half of the muscle can be rendered weak by exposure to low [Ca2+]o. Stretch allowed t...

journal_title：Annals of the New York Academy of Sciences

authors： ter Keurs HE,Diao N,Deis NP

更新日期：2010-02-01 00:00:00

abstract：:Cell doctrine is the foundational paradigm of Euro-American medicine and biology. Even without stepping outside that tradition, one may imagine alternate models of the body such as a fluid model in which cells do not exist or a model wherein cells are described as overlapping fields of molecular organization in space ...

journal_title：Annals of the New York Academy of Sciences

authors： Theise ND

更新日期：2009-08-01 00:00:00

abstract：:A permanent decrease was seen in the prevalence of lice infestation among population of the Ukraine from 1990-2004. The prevalence of lice infestation among children under 14 years of age was 6-27 times more than that in adults. The highest figures were among children 7-14 years old. During all of the observation peri...

journal_title：Annals of the New York Academy of Sciences

authors： Kurhanova I

更新日期：2006-10-01 00:00:00

abstract：:Cochlear implants (CIs) provide impressive speech perception for persons with severe hearing loss, but many CI recipients fail in perceiving speech prosody and music. Successful rehabilitation depends on cortical plasticity in the brain and postoperative measures. The present study evaluates the behavioral and neurolo...

journal_title：Annals of the New York Academy of Sciences

authors： Petersen B,Mortensen MV,Gjedde A,Vuust P

更新日期：2009-07-01 00:00:00

abstract：:Recent studies suggest that the symptoms associated with endometriosis are the result of local peritoneal inflammation. Increased concentrations of activated pelvic macrophages and lymphocytes and the elevated levels of specific cytokines and growth factors reviewed above support this hypothesis. The precise roles of ...

journal_title：Annals of the New York Academy of Sciences

authors： Taylor RN,Ryan IP,Moore ES,Hornung D,Shifren JL,Tseng JF

更新日期：1997-09-26 00:00:00

abstract：:Between 4 and 13% of people with schizophrenia commit suicide and between 25 and 50% make a suicide attempt, a reflection of the devastating toll this syndrome takes on the quality of life, that is, the subjective and objective sense of well-being. Many risk factors for suicide in schizophrenia have been identified, t...

journal_title：Annals of the New York Academy of Sciences

authors： Meltzer HY

更新日期：2001-04-01 00:00:00

abstract：:The understanding and control of embryo implantation represents the major challenge for assisted reproductive technologies. Along with developments in basic research and efforts to optimize embryo quality, the improvement of noninvasive and reliable methods to assess uterine receptivity constitutes an important step t...

journal_title：Annals of the New York Academy of Sciences

authors： Fanchin R

更新日期：2001-09-01 00:00:00

abstract：:A nonparametric method, isotonic regression, is proposed for analyzing a dose-response relationship and for assessing a threshold value. There are several advantages of this method compared to parametric models. No specific form of the relationship (type of model and use of the covariates) is required. The only assump...

journal_title：Annals of the New York Academy of Sciences

authors： Ulm K

更新日期：1999-01-01 00:00:00

abstract：:Until now, neoadjuvant therapy plus surgical resection of the primary tumor and potential metastatic lymph nodes (LNs) has been the current optimal treatment for locally advanced thoracic esophageal cancer (EC). LN metastasis is one of the most negative prognostic factors for thoracic esophageal squamous cell carcinom...

journal_title：Annals of the New York Academy of Sciences

authors： Wang Z,Mao Y,Gao S,Li Y,Tan L,Daiko H,Liu S,Chen C,Koyanagi K,He J

更新日期：2020-12-01 00:00:00

abstract：:We have used site-directed mutagenesis to investigate the contributions of widely distributed residues in the thymosin beta-4 (Tbeta4) sequence to the formation and stability of the actin-Tbeta4 complex. Equilibrium and kinetic studies of actin binding were performed by monitoring the change in fluorescence of an N-io...

journal_title：Annals of the New York Academy of Sciences

authors： Au JK,De La Cruz EM,Safer D

更新日期：2007-09-01 00:00:00

abstract：:On occasion, emerging scientific fields intersect and great discoveries result. In the last decade, the discovery of regulatory T cells (T(reg)) in immunity has revolutionized our understanding of how the immune system is controlled. Intersecting the rapidly emerging field of T(reg) function, has been the discovery th...

journal_title：Annals of the New York Academy of Sciences

authors： Pino-Lagos K,Benson MJ,Noelle RJ

更新日期：2008-11-01 00:00:00

abstract：:Peroxisomes are capable of oxidizing a variety of substrates including (poly)unsaturated enoyl-CoA esters. The beta-oxidation of unsaturated enoyl-CoA esters in peroxisomes, and also in mitochondria, is not just chain-shortening but also involves the metabolizing of pre-existing carbon-to-carbon double bonds. In addit...

journal_title：Annals of the New York Academy of Sciences

authors： Hiltunen JK,Filppula SA,Koivuranta KT,Siivari K,Qin YM,Häyrinen HM

更新日期：1996-12-27 00:00:00

abstract：:The osteoclast (OCL) is derived from the cells in monocyte-macrophage lineage. The earliest identifiable OCL precursor is the granulocyte-macrophage colony-forming unit (CFU-GM), which gives rise to granulocytes, monocytes, and OCL. CFU-GM-derived cells then differentiate to committed OCL precursors, which are post-mi...

journal_title：Annals of the New York Academy of Sciences

authors： Roodman GD

更新日期：2006-04-01 00:00:00

abstract：:During the annual Ramazzini Days, the Mayor of Carpi confers the Ramazzini Award on scientists deemed by the Collegium Ramazzini to have made outstanding contributions to furthering the aims of Bernardino Ramazzini in safeguarding public health. Dr. Lorenzo Tomatis was the Ramazzini Award recipient in 2005, and the pr...

journal_title：Annals of the New York Academy of Sciences

authors： Tomatis L

更新日期：2006-09-01 00:00:00

abstract：:In this paper, we consider minimizing the action functional as a method for numerically discovering periodic solutions to the n-body problem. With this method, we can find a large number of choreographies and other more general solutions. We show that most of the solutions found, including all but one of the choreogra...

journal_title：Annals of the New York Academy of Sciences

authors： Vanderbei RJ

更新日期：2004-05-01 00:00:00

abstract：:Since the late sixties, several new antifungal drugs have become available. Initially, they were all intended for topical use, and, consequently, animal and human pharmacology always primarily aimed at confirming therapeutic efficacy. With the new tendency for the development of orally active antifungal drugs, human a...

journal_title：Annals of the New York Academy of Sciences

authors： Cauwenbergh G,Van Cutsem J

更新日期：1988-01-01 00:00:00

abstract：:Most research on reading skill acquisition in deaf individuals has been conducted from the perspective of a hearing child learning to read. This approach may limit our understanding of how a deaf child approaches the task of learning to read and successfully acquires reading skills. An alternative approach is to consi...

journal_title：Annals of the New York Academy of Sciences

authors： Dye MW,Hauser PC,Bavelier D

更新日期：2008-12-01 00:00:00