HLA-B27 and HLA-B51 determination in Tunisian healthy subjects and patients with suspected ankylosing spondylitis and Behçet's disease.

abstract：:Hereditary episodic ataxia (EA) syndromes are rare monogenic disorders that are phenotypically and genetically heterogeneous. The number of identified EA phenotypes is expanding. So far, mutations have been identified in four genes, all coding for membrane proteins including ion channels and transporters. The study of...

journal_title：Annals of the New York Academy of Sciences

authors： Jen JC

更新日期：2008-10-01 00:00:00

abstract：:New aggressive pathogens are responsible for the increasing incidence and difficult management of infections. Modern epidemics such as diabetes are frequently complicated by severe infections with subsequent high morbidity. Diagnosis (essentially early detection of infection) and also management decision making pose c...

journal_title：Annals of the New York Academy of Sciences

authors： Israel O,Keidar Z

更新日期：2011-06-01 00:00:00

abstract：:We compared the expression of target genes of Hedgehog/Patched signaling in ovarian fibromas and ovarian dermoids. We noted that high levels of SHH appear almost regularly, especially in dermoids, usually accompanied by increased expression of SMO. GLI overexpression does not coincide with that of PTCH. Loss of hetero...

journal_title：Annals of the New York Academy of Sciences

authors： Levanat S,Musani V,Komar A,Oreskovic S

更新日期：2004-12-01 00:00:00

abstract：:Bacterial cell division is facilitated by the divisome, a dynamic multiprotein assembly localizing at mid-cell to synthesize the stress-bearing peptidoglycan and to constrict all cell envelope layers. Divisome assembly occurs in two steps and involves multiple interactions between more than 20 essential and accessory ...

journal_title：Annals of the New York Academy of Sciences

authors： Egan AJ,Vollmer W

更新日期：2013-01-01 00:00:00

abstract：:During relapses in relapsing-remitting multiple sclerosis (RRMS), serum soluble HLA class I surface antigen (sHLA-I) levels are reported to either decrease or remain unchanged, whereas serum sHLA-II levels increase. Interferon-beta1b therapy was recently reported to increase serum sHLA-I in RRMS. In the present prospe...

journal_title：Annals of the New York Academy of Sciences

authors： Minagar A,Adamashvilli I,Jaffe SL,Glabus MF,Gonzalez-Toledo E,Kelley RE

更新日期：2005-06-01 00:00:00

abstract：:In conclusion, 5-HT has been shown to contract both circular and longitudinal muscle layers of human terminal ileum. By the use of selective antagonists, the receptors mediating these actions have been identified. In the circular muscle of human small intestine, 5-HT-induced contraction is mediated via a receptor of t...

journal_title：Annals of the New York Academy of Sciences

authors： Borman RA,Burleigh DE

更新日期：1997-05-30 00:00:00

abstract：:The development of an integrated system for the continuous, automated production of pure cell culture derived proteins is discussed. The system comprises a cell culture subunit for the continuous culture of mammalian cells and a purification subunit linked on-line to the cell culture subunit. The cells are compartment...

journal_title：Annals of the New York Academy of Sciences

authors： Grandics P,Szathmary S,Szathmary Z,O'Neill T

更新日期：1991-12-27 00:00:00

abstract：:In the present study, we have utilized the transglutaminase (TGase) enzyme to modify the primary structure of VIP with diaminopropane (DAP) at the level of the Gln16. We have investigated the conformational stability of VIP and VIP-DAP in solution by limited proteolysis experiments. The VIP-DAP appears to be more resi...

journal_title：Annals of the New York Academy of Sciences

authors： Caraglia M,Dicitore A,Giuberti G,Cassese D,Lepretti M,Cartenì M,Abbruzzese A,Stiuso P

更新日期：2006-07-01 00:00:00

abstract：:Regulatory interactions have been shown to occur between all the testicular cell types considered. The paracrine factors mediating these interactions generally influence either cellular growth or differentiation. The regulation of cellular growth is essential in the developing testis and is required for the maintenanc...

journal_title：Annals of the New York Academy of Sciences

authors： Skinner MK,Norton JN,Mullaney BP,Rosselli M,Whaley PD,Anthony CT

更新日期：1991-01-01 00:00:00

abstract：:Mustard gas (sulfur mustard, SM), a highly vesicating chemical warfare agent, was first deployed in warfare in 1917 and recently during the Iraq-Iran war (1980s) and Syrian conflicts (2000s); however, the threat of exposure from stockpiles and old artillery shells still looms large. Whereas research has been long ongo...

journal_title：Annals of the New York Academy of Sciences

authors： Mishra N,Raina K,Agarwal R

更新日期：2020-12-10 00:00:00

abstract：:The levels of cellular glutathione (GSH) and reactive oxygen species (ROS) simultaneously determined by fluorometric measurement, may provide important information on pro-oxidative and antioxidative balance. The dual effect of quercetin antioxidant and pro-oxidant activity was proposed from different studies. Our stud...

journal_title：Annals of the New York Academy of Sciences

authors： Kim GN,Jang HD

更新日期：2009-08-01 00:00:00

abstract：:The innervation of muscles in patients with the post-polio syndrome (PPS) may differ from limb to limb or even within the same limb because of the segmental nature of the initial involvement and the varying degree of subsequent recovery. Consequently, the compensatory effort of the neighboring muscles varies even in t...

journal_title：Annals of the New York Academy of Sciences

authors： Dalakas MC

更新日期：1995-05-25 00:00:00

abstract：:Rehabilitation aims to lessen the physical and cognitive impairments and disabilities of patients with stroke, multiple sclerosis, spinal cord or brain injury, and other neurologic diseases. Conventional approaches beyond compensatory adjustments to disability may be augmented by applying some of the myriad experiment...

journal_title：Annals of the New York Academy of Sciences

authors： Dobkin BH

更新日期：2004-12-01 00:00:00

abstract：:Tight junctions (TJs) regulate paracellular barriers and claudins (Cld) form the backbone of TJ strands. To elucidate the molecular mechanism of claudin polymer formation, TJs were reconstituted by claudin transfection of TJ-free HEK293 cells. Therewith, typical TJ stands can be found at cell-cell contacts. In additio...

journal_title：Annals of the New York Academy of Sciences

authors： Rossa J,Lorenz D,Ringling M,Veshnyakova A,Piontek J

更新日期：2012-06-01 00:00:00

abstract：:This article reviews some of the early work that has been performed to investigate the potential roles of circulating nucleic acids as prediction markers in acute illness and injury. Circulating DNA and RNA concentrations are elevated early in patients with trauma, stroke and ACS, and are generally highest in patients...

journal_title：Annals of the New York Academy of Sciences

authors： Rainer TH,Lam NY

更新日期：2006-09-01 00:00:00

abstract：:The extreme toxicity of organophosphorous-based compounds has been known since the late 1930s. Starting in the mid-1940s, many nations throughout the world have been producing large quantities of organophosphorous (OP) nerve agents. Huge stockpiles of nerve agents have since developed. There are reportedly more than 2...

journal_title：Annals of the New York Academy of Sciences

authors： LeJeune KE,Dravis BC,Yang F,Hetro AD,Doctor BP,Russell AJ

更新日期：1998-12-13 00:00:00

abstract：:Data show that specifically chelating lysosomal redox-active iron can prevent most H(2)O(2)-induced DNA damage. Lysosomes seem to contain the major pool of redox-active labile iron within the cell. Under oxidative stress conditions, this iron may then relocate to the nucleus and play an important role for DNA damage b...

journal_title：Annals of the New York Academy of Sciences

authors： Kurz T,Leake A,von Zglinicki T,Brunk UT

更新日期：2004-06-01 00:00:00

abstract：:Nuclear receptors are transcription factors that are activated by ligands and subsequently bind to regulatory regions in target genes, thereby modulating their expression. Nuclear receptors thus allow the organism to integrate signals coming from the environment and to adapt by modifying the expression levels of relev...

journal_title：Annals of the New York Academy of Sciences

authors： Bocher V,Pineda-Torra I,Fruchart JC,Staels B

更新日期：2002-06-01 00:00:00

abstract：:We conducted an experimental study of the interaction and coalescence of two drops (of the same fluid) or bubbles translating under the action of buoyancy in a cylindrical tube. The close approach of two Newtonian fluid particles of different size in a non-Newtonian continuous phase was examined using image analysis, ...

journal_title：Annals of the New York Academy of Sciences

authors： Al-Matroushi E,Borhan A

更新日期：2009-04-01 00:00:00

abstract：:The treatment of substance use disorders has always been challenging because multiple neurotransmitters mediate addiction. However, with smoking being the leading cause of preventable death and the recent opioid epidemic in the United States, the search for novel solutions becomes more imperative. In this review, we d...

journal_title：Annals of the New York Academy of Sciences

authors： Xu A,Kosten TR

更新日期：2020-03-08 00:00:00

abstract：:Tick burdens cause direct damage to hosts and transmit several disease agents, the majority of which are secreted into feeding lesions through tick salivary glands. Reduced incidence of naturally transmitted tick-borne diseases was recently observed among cattle immunized with tick salivary gland extracts (TSGE). The ...

journal_title：Annals of the New York Academy of Sciences

authors： Jittapalapong S,Phichitrasilp T,Chanphao H,Rerkamnuychoke W,Stich RW

更新日期：2008-12-01 00:00:00

abstract：:Human mesenchymal stem cells (hMSCs) from bone marrow are a source of osteoblast progenitors in vivo, and under appropriate conditions they differentiate into osteoblasts ex vivo. The cells provide a convenient cell culture model for the study of osteogenic tissue repair in an experimentally accessible system. Recent ...

journal_title：Annals of the New York Academy of Sciences

authors： Gregory CA,Gunn WG,Reyes E,Smolarz AJ,Munoz J,Spees JL,Prockop DJ

更新日期：2005-05-01 00:00:00

abstract：:The article gives an overview on worldwide efforts to eliminate chemical weapons and facilities for their production in the context of the implementation of the 1997 Chemical Weapons Convention (CWC). It highlights the objectives of the Organisation for the Prohibition of Chemical Weapons (OPCW), the international age...

journal_title：Annals of the New York Academy of Sciences

authors： Trapp R

更新日期：2006-09-01 00:00:00

abstract：:Stationary-phase mutation (a subset of which was previously called adaptive mutation) occurs in apparently nondividing, stationary-phase cells exposed to a nonlethal genetic selection. In one experimental system, stationary-phase reversion of an Escherichia coli F'-borne lac frameshift mutation occurs by a novel molec...

journal_title：Annals of the New York Academy of Sciences

authors： Lombardo MJ,Torkelson J,Bull HJ,McKenzie GJ,Rosenberg SM

更新日期：1999-05-18 00:00:00

abstract：:A mouse strain lacking SMP30 can be regarded as a strain showing ultimate decrease of the SMP30 molecule. After three months of age, SMP30-KO mice had an increased mortality rate, compared with the SMP30-WT mice, all of which remained alive. Electron microscopic observation of the hepatocytes from 12-month-old SMP30-K...

journal_title：Annals of the New York Academy of Sciences

authors： Maruyama N,Ishigami A,Kuramoto M,Handa S,Kubo S,Imasawa T,Seyama K,Shimosawa T,Kasahara Y

更新日期：2004-06-01 00:00:00

abstract：:Cytokines are powerful mediators of biologic responses in the CNS and may contribute to cellular injury in pathophysiologic states. In order to better understand the actions of cytokines in the intact mammalian CNS, a transgenic approach was employed that targeted the expression of different cytokines to astrocytes in...

journal_title：Annals of the New York Academy of Sciences

authors： Campbell IL

更新日期：1998-05-01 00:00:00

abstract：:Sarcopenia is the involuntary loss of skeletal muscle mass and strength that occurs with aging, resulting in physical frailty. One potential explanation for sarcopenia is the failure of muscle to regenerate after damage, some of which may be due to changes in the function of satellite cells. Recent studies have identi...

journal_title：Annals of the New York Academy of Sciences

authors： Machida S,Narusawa M

更新日期：2006-05-01 00:00:00

abstract：:Clostridium difficile infection, also known as C. difficile-associated diarrhea (CDAD), is the most common cause of nosocomial diarrhea, typically initiated by the use of broad-spectrum antibiotics that disrupt gut flora, thereby allowing C. difficile to proliferate. It is an increasing cause of morbidity and mortalit...

journal_title：Annals of the New York Academy of Sciences

authors： Sears P,Ichikawa Y,Ruiz N,Gorbach S

更新日期：2013-07-01 00:00:00

abstract：:The discovery of cell-free nucleic acids in plasma has opened up new possibilities for noninvasive clinical diagnosis. We demonstrate the presence of cell-free fetal RNA in maternal plasma, indicating that plasma fetal RNA might be used as a marker for noninvasive prenatal diagnosis. ...

journal_title：Annals of the New York Academy of Sciences

authors： Poon LL,Leung TN,Lau TK,Lo YM

更新日期：2001-09-01 00:00:00

abstract：:The impact of climate change on biodiversity is now evident, with the direct impacts of changing temperature and rainfall patterns and increases in the magnitude and frequency of extreme events on species distribution, populations, and overall ecosystem function being increasingly publicized. Changes in the climate sy...

journal_title：Annals of the New York Academy of Sciences

authors： Maxwell SL,Venter O,Jones KR,Watson JE

更新日期：2015-10-01 00:00:00