Abstract：
:Pregnant rabbits in their first and second "trimesters" of gestation were used in a controlled study to evaluate the teratogenicity of fluorescein sodium. Injections of the drug were given in doses comparable to those planned for human administration. No abortions or defects apparent at birth or as delayed manifestations were evident as a result of the drug therapy.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
McEnerney JK,Wong WP,Peyman GAdoi
10.1016/0002-9394(77)90508-6subject
Has Abstractpub_date
1977-12-01 00:00:00pages
847-50issue
6eissn
0002-9394issn
1879-1891pii
0002-9394(77)90508-6journal_volume
84pub_type
杂志文章abstract：PURPOSE:To determine whether polymorphisms in the Complement Factor H (CFH) gene and the Hemicentin-1 gene at the ARMD1 locus are associated with dry age-related macular degeneration (AMD) in Japanese patients. DESIGN:Clinically relevant laboratory investigation. METHODS:Eighty unrelated Japanese patients with dry AM...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.07.030
更新日期：2006-12-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of transconjunctival Müller muscle recession and graded levator disinsertion for eyelid retraction in patients with thyroid-related orbitopathy (TRO). DESIGN:Retrospective consecutive case series. METHODS:Medical record review of 78 TRO patients (107 eyelids) who underwent surgery for...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.02.034
更新日期：2005-07-01 00:00:00
abstract：PURPOSE:To determine characteristics of peri-dome choroidal deepening (PDCD) surrounding dome-shaped maculas (DSMs) in highly myopic eyes. DESIGN:Observational case series. METHODS:Applying swept-source optical coherence tomography, we examined the posterior pole of highly myopic eyes with DSMs. RESULTS:The study in...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.09.009
更新日期：2017-11-01 00:00:00
abstract：:Eight patients were treated for Pseudomonas endophthalmitis associated with the implantation of contaminated intraocular lenses. All patients showed clinical signs of infection (loss of red reflex, diminished visual acuity, and intraocular lens coagulum) and P. aeruginosa was isolated from vitreous aspirates and unuse...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90569-5
更新日期：1979-11-01 00:00:00
abstract：PURPOSE:To determine if there are variations in regional practice patterns for retinal detachment repair in the United States. DESIGN:Retrospective, noninterventional, cross-sectional study. METHODS:Year 2009 Medicare fee-for-service claims for retinal detachment repair were aggregated in 4 geographic regions and eva...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.11.034
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:To determine photoreceptor oxidative stress and damage in sympathetic ophthalmia (SO). DESIGN:Immunohistologic study. METHODS:Eight formalin-fixed and paraffin-embedded human globes with typical histologic features of SO and five age-matched globes without intraocular inflammation (controls) were retrieved fr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.03.026
更新日期：2008-12-01 00:00:00
abstract：PURPOSE:To examine clinical outcomes in deep anterior lamellar keratoplasty (DALK) for keratoconus using contemporary techniques in a multisurgeon public healthcare setting. DESIGN:Consecutive, retrospective case series. METHODS:Setting: Moorfields Eye Hospital, London, United Kingdom. STUDY POPULATION:Consecutive c...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2019.01.022
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To verify the short-term influence of an orally administered nonsteroidal anti-inflammatory drug on the intraocular pressure (IOP) of primary open-angle glaucoma patients in therapy with a topical prostaglandin analog. DESIGN:Randomized cross-over double-blind study. METHODS:Sixteen adults with primary open-a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2004.11.062
更新日期：2006-02-01 00:00:00
abstract：PURPOSE:To analyze the risk factors, clinical characteristics, management, and treatment outcomes of culture-proven cases of Moraxella keratitis at our center. DESIGN:Retrospective observational case series. METHODS:Thirty-nine culture-proven cases of Moraxella keratitis (39 eyes) diagnosed and treated between Januar...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.08.055
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:To compare the effectiveness of arcuate keratotomy (AK) performed with a femtosecond laser (FSL) or Hanna keratome (Moria, Anthony, France) for correction of postkeratoplasty astigmatism. DESIGN:Prospective, randomized study. METHODS:This clinical study included 20 eyes. Two groups of 10 eyes underwent AK usi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2008.12.017
更新日期：2009-05-01 00:00:00
abstract：PURPOSE:To report a neovascular age-related macular degeneration pattern refractory to ranibizumab. DESIGN:Retrospective, observational case series. METHODS:Between March and May 2009, cases with neovascular age-related macular degeneration refractory to ranibizumab were investigated with indocyanine green angiograph...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.05.035
更新日期：2010-11-01 00:00:00
abstract：PURPOSE:To describe a simplified new technique for repositioning and attaching a suture to the haptic of a displaced posterior chamber intraocular lens (IOL). METHODS:We describe a double-knot technique for repositioning and transscleral suture fixation of a subluxed posterior chamber IOL after penetrating keratoplast...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00244-5
更新日期：1999-11-01 00:00:00
abstract：PURPOSE:To evaluate the retinal toxicity of intravitreal bevacizumab in an animal model. DESIGN:Animal study. METHODS:Bevacizumab was injected into the vitreous of one eye of each of eight Dutch-belted rabbits; the other eye served as a control. Four rabbits received a dose of 1.25 mg/0.05 ml of bevacizumab intravitr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.03.058
更新日期：2006-07-01 00:00:00
abstract：PURPOSE:To determine if a 1-day, 1-eye trial of latanoprost 0.005% was predictive of the 1-month intraocular pressure response in patients with uncontrolled open-angle glaucoma on maximally tolerated medical therapy without latanoprost. METHODS:One eye of 39 consecutive patients was enrolled in prospective trial of la...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(01)01253-3
更新日期：2001-12-01 00:00:00
abstract：:With a recently developed technique for quantifying the geometry of the anterior chamber in optical cross section (slit-lamp photography using the Scheimpflug principle and computer correction for the optical effects of the cornea), we studied the iris contour before and after iridotomy in six patients with narrow ant...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76341-x
更新日期：1990-09-15 00:00:00
abstract：PURPOSE:beta-Adrenergic blocking drugs lower intraocular pressure. The question of whether these drugs also alter, either directly or indirectly, orbital hemodynamics is potentially of great importance for patients with normal-tension glaucoma who may have some degree of reversible vasospasm. METHODS:We compared the e...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(14)72604-2
更新日期：1995-08-01 00:00:00
abstract：PURPOSE:To examine the development and management of glaucoma in patients with ocular chemical burns. DESIGN:Retrospective, observational case series. METHODS:setting: University of Washington Eye Clinics. patient population: Twenty-nine eyes (18 patients) with ocular chemical burns seen between 1997 and 2010 with a ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.03.026
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:To report corneal histopathology associated with keratectasia after laser in situ keratomileusis (LASIK) and to evaluate the thickness of the calculated residual stromal bed in two cases and those in the literature. DESIGN:Interventional case reports. METHODS:Three eyes of two patients developed keratectasia ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01656-2
更新日期：2002-11-01 00:00:00
abstract：PURPOSE:To evaluate posterior subtenon injection of triamcinolone acetonide for refractory diabetic macular edema (DME). DESIGN:Retrospective, interventional, case series. METHODS: SETTING:Clinical practice. PATIENT POPULATION:Patients with persistent clinically significant DME involving the center of the fovea 3 o...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.09.038
更新日期：2005-02-01 00:00:00
abstract：PURPOSE:To report ocular findings in the mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS syndrome) in a family with the A to G 3243 mitochondrial (mt) DNA point mutation. METHODS:Case reports. Ocular findings are described from four family members with the MELAS associated A to G 3243...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00057-4
更新日期：1999-07-01 00:00:00
abstract：PURPOSE:To describe a case of spontaneous retrobulbar hemorrhage in type IV Ehlers-Danlos syndrome, a disorder characterized by vascular fragility and associated severe bleeding problems. METHODS:Observational case report. Spontaneous unilateral retrobulbar hemorrhage in a 22-year-old man with type IV Ehlers-Danlos sy...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01325-3
更新日期：2002-03-01 00:00:00
abstract：PURPOSE:To determine iridocorneal angle changes produced after 2 years of implantable collamer lens (ICL) V4c (STAAR Surgical AG, Nidau, Switzerland) placement by Fourier-domain optical coherence tomography (FD-OCT). DESIGN:Prospective interventional case series. METHODS:In 54 eyes of 27 myopic subjects FD-OCT iridoc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.06.018
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:To estimate point prevalence of uveal melanoma in the patients with germline BAP1 pathogenic variant. DESIGN:Cohort study with risk assessment using Bayesian analysis. METHODS:The point prevalence estimate was obtained by Bayes's rule of reverse conditional probabilities. The probability of uveal melanoma giv...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.12.005
更新日期：2020-12-11 00:00:00
abstract：PURPOSE:To report a case of neonatal orbital ganglioglioma originating from ectopic neural tissue. METHOD:Case report. RESULTS:An African-American male presented at birth with proptosis and expansion of the left orbit. A discrete soft-tissue mass was located inferolateral to the globe, which proved to be a gangliogli...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00288-3
更新日期：2000-01-01 00:00:00
abstract：PURPOSE:To report the association of antiretinal antibodies in patients with bilateral cystoid macular edema and retinitis pigmentosa. METHODS:In a prospective study, 30 consecutive patients with bilateral cystoid macular edema and retinitis pigmentosa were tested for antiretinal antibodies. As control subjects, 30 co...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00446-2
更新日期：1999-05-01 00:00:00
abstract：PURPOSE:To assess the potential effect of intravitreal bevacizumab (IVB) (Avastin) on retinal function and anatomic recovery in eyes with choroidal neovascularization attributable to pathological myopia (mCNV). DESIGN:Retrospective case series. METHODS:setting: Institutional. patient population: Sixty-three eyes of 6...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.07.017
更新日期：2009-01-01 00:00:00
abstract：:In seven eyes of six patients (four men and two women, 55 to 72 years old), with macular edema associated with severe carotid artery stenosis, the ipsilateral carotid obstruction was 90% or more. Concomitant fundus signs, such as midperipheral retinal hemorrhages, retinal arterial narrowing, and neovascularization of ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90071-1
更新日期：1986-10-15 00:00:00
abstract：:We studied the use of human retinal pigment epithelial cells cultured on a collagen support as a potential transplantation therapy to replace diseased or damaged retinal pigment epithelium. Using a transvitreal approach, we transplanted human retinal pigment epithelial cells attached to either a sheet of noncross-link...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73079-x
更新日期：1994-02-15 00:00:00
abstract：PURPOSE:To provide a detailed review of current clinical guidelines for the diagnosis, work-up and treatment of autoimmune retinopathy and to preview briefly possible future therapies. DESIGN:Perspective based on literature review and clinical expertise. METHODS:Interpretation of current literature, relying on the au...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ajo.2013.09.019
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:To report rapidly progressive rhino-orbitocerebral mucormycosis in a 47-year-old woman with both diabetes mellitus and the acquired immunodeficiency syndrome (AIDS). METHOD:Case report including postmortem examination of the eyes, orbit, and brain of a patient with rhino-orbitocerebral mucormycosis, diabetes m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70392-7
更新日期：1996-12-01 00:00:00
