Abstract：
PURPOSE:To verify the short-term influence of an orally administered nonsteroidal anti-inflammatory drug on the intraocular pressure (IOP) of primary open-angle glaucoma patients in therapy with a topical prostaglandin analog. DESIGN:Randomized cross-over double-blind study. METHODS:Sixteen adults with primary open-angle glaucoma, receiving 0.005% latanoprost eyedrops once daily, were treated with a single dose of either 100 mg nimesulide or placebo. IOP was recorded at baseline and at 1, 2, 4, 8, 12, and 24 hours. RESULTS:After nimesulide administration, there was a decrease in IOP (with a fall at the second hour, P<.01) that remained significant 8 hours later (P<.05). At 12 and 24 hours, there were unremarkable IOP differences between the two regimens. CONCLUSIONS:In patients with primary open-angle glaucoma, single-dose nimesulide significantly enhances the latanoprost-induced IOP-lowering effects during the short plasma half-life of this non-steroidal anti-inflammatory drug.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Costagliola C,Parmeggiani F,Caccavale A,Sebastiani Adoi
10.1016/j.ajo.2004.11.062subject
Has Abstractpub_date
2006-02-01 00:00:00pages
379-81issue
2eissn
0002-9394issn
1879-1891pii
S0002-9394(04)01461-8journal_volume
141pub_type
杂志文章,随机对照试验abstract：PURPOSE:To determine whether central corneal thickness (CCT) is a risk factor for visual field loss development among patients diagnosed with preperimetric glaucomatous optic neuropathy (GON). DESIGN:Observational cohort study. METHODS:The study included 98 eyes of 98 patients with GON, with a mean follow-up time of ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00484-7
更新日期：2003-11-01 00:00:00
abstract：PURPOSE:To evaluate outcomes of patients treated with intensive intravitreal therapy and to describe the evolution of quantitative real-time polymerase chain reaction (qPCR) in patients treated for acute retinal necrosis (ARN) syndrome. DESIGN:Retrospective observational case series. METHODS:This study included 25 ey...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2019.08.007
更新日期：2019-12-01 00:00:00
abstract：:We managed three cases of congenital iris stromal cysts and compared them with 22 cases in the published reports to delineate the clinical features of this condition and determine the best treatment. Our first patient, a 5-month-old girl, had injection of a cyst with trichloroacetic acid, but developed a cataract and ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0002-9394(14)71291-7
更新日期：1993-08-15 00:00:00
abstract：PURPOSE:To report the prevalence rates of anisometropia in a school population and determine the relative contribution of refractive power and axial length to the measured anisometropia. DESIGN:Population-based cross-sectional study. METHODS:Autorefraction, keratometry, and ultrasonography studies were made. SETTING...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.10.028
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:To evaluate low- vs high-dose plaque brachytherapy for juxtapapillary choroidal melanoma. DESIGN:Retrospective interventional case series. METHODS:Setting: Single institution. STUDY POPULATION:Forty-seven patients with juxtapapillary choroidal melanoma. INTERVENTION:Iodine-125 plaque brachytherapy. Eyes wer...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.11.008
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:To present a case of choroidal neovascularization associated with sympathetic ophthalmia successfully treated with photocoagulation. DESIGN:Interventional case report. METHODS:A 41-year-old man with a history of penetrating injury right eye, as well as sympathetic ophthalmia left eye, developed a classic chor...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01044-3
更新日期：2001-10-01 00:00:00
abstract：PURPOSE:To measure the changes in optic disk morphology after unilateral disk hemorrhage and to compare the changes between eyes. DESIGN:Observational case series. METHODS:Ten glaucoma patients who had a unilateral disk hemorrhage were enrolled. The baseline measurements obtained by Heidelberg Retina Tomograph (HRT) ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01791-9
更新日期：2002-12-01 00:00:00
abstract：:Holes of the peripheral retina, defined as full-thickness breaks of trophic origin with no associated flap or free operculum, were found in 136 (2.4%) eyes from 2,800 autopsied subjects. Primary retinal holes (those with no indication of a proximal causative lesion and with no lattice degeneration in either eye) occur...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90239-8
更新日期：1978-09-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90364-9
更新日期：1988-09-15 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00709-8
更新日期：2003-12-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71344-3
更新日期：1993-09-15 00:00:00
abstract：PURPOSE:To investigate thermal changes produced by a chandelier fiber probe (CFP). DESIGN:Interventional single case report and laboratory investigation. METHODS:When CFP was used for 25-gauge vitrectomy, an abnormal odor was emitted, and the CFP was instantly removed. To investigate this incident, the thermal change...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.07.049
更新日期：2007-01-01 00:00:00
abstract：:Twenty-two of 23 obligate female carriers in nine families with known X-chromosome-linked retinitis pigmentosa were detected on the basis of abnormal full-field electroretinograms (ERGs). Only 14 of these carriers had fundus findings characteristic of the carrier state. Electroretinograms of carriers were either reduc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90231-9
更新日期：1979-04-01 00:00:00
abstract：PURPOSE:To determine the proper management of congenital dacryocystocele. DESIGN:Retrospective interventional case series. METHODS: SETTINGS:Clinical practice. STUDY POPULATION:Twenty-seven consecutive patients with 29 congenital dacryocystoceles who presented from 1987 through 2006. MAIN OUTCOME MEASURES:The char...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.05.043
更新日期：2006-11-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90126-5
更新日期：1978-12-01 00:00:00
abstract：:We reviewed the results of vitreous surgery in 12 eyes of 12 patients with tractional macular detachment from Toxocara canis. We performed a vitrectomy and membrane peeling in all eyes, with additional scleral buckling in four eyes. After a minimum of six months' follow-up, ten of the 12 eyes (83%) had complete retina...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73253-2
更新日期：1989-07-15 00:00:00
abstract：PURPOSE:To document and study the relationship between perimetric sensitivity and retinal thickness at the foveal and parafoveal points in eyes with macular edema associated with branch retinal vein occlusion. METHODS:A prospective study was performed using the central 10-2 Humphrey perimetry program and optical coher...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00722-4
更新日期：2001-01-01 00:00:00
abstract：:A 32-year-old woman developed bilateral blindness along with severe preeclampsia of pregnancy. Ophthalmoscopic examination disclosed chalky-white optic disks with only minimal changes in the retinal vasculature. After caesarean section, the preeclampsia improved, and complete return of visual acuity occurred during a ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74914-1
更新日期：1980-09-01 00:00:00
abstract：:To evaluate the ability of the Friedmann visual field analyzer to determine visual threshold and the depth of visual field defects, we correlated the visual threshold determined kinetically (Goldmann perimeter) with the static threshold (Friedmann analyzer) in various parts of the central field. We found the following...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(83)90390-2
更新日期：1983-05-01 00:00:00
abstract：:Patients with presumed ocular histoplasmosis syndrome were typed for HLA-A, B, C, and DR antigens. It was found that 21 (81%) of 26 of the presumed ocular histoplasmosis syndrome patients with disciform macular scarring and 8 (62%) of 13 of the presumed ocular histoplasmosis syndrome patients with peripheral atrophic ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1980-01-01 00:00:00
abstract：PURPOSE:To determine the natural history of asymptomatic, clinical rhegmatogenous retinal detachment. DESIGN:Single observer, prospective, consecutive, observational case series. METHODS:Consecutive patients were included who were referred to the author's clinical practice with rhegmatogenous retinal detachment exten...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.01.014
更新日期：2005-05-01 00:00:00
abstract：PURPOSE:To analyze the features of retinal detachment (RD) occurring after cataract surgery performed by Kelman phacoemulsification (KPE) and to identify any potential correlations between KPE intraoperative complications and the features of RD (incidence apart) as well as the final visual outcome. DESIGN:Intervention...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01347-8
更新日期：2002-05-01 00:00:00
abstract：PURPOSE:A defect in the visual field is one of the serious complications of macular hole surgery. We investigated the relationship between the occurrence of visual field defect and the location of infusion cannula and air pressure during fluid-air exchange. METHODS:We studied 100 eyes from 90 patients with macular hol...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00597-3
更新日期：2000-11-01 00:00:00
abstract：PURPOSE:To report a model of choroidal neovascularization feeder vessels that reconciles current histologic, angiographic, and clinical data, and to report experimental studies that investigate the potential of indocyanine-green-dye-enhanced photocoagulation to improve feeder-vessel treatment. METHODS:A model of choro...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00411-0
更新日期：2000-04-01 00:00:00
abstract：:Bilateral homonymous hemianopia occurred in 15 patients seen during a four-year period. Persons with this visual deficit had similarly shaped visual field defects on corresponding sides of the vertical midline for each eye, equal visual acuity which is generally normal, and normal pupil and fundus examinations. The mo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90303-3
更新日期：1978-10-01 00:00:00
abstract：:Two patients with massive epithelium-lined inclusion cysts of the orbit became symptomatic five and 16 years after scleral buckling. Each patient described diplopia and displacement of the previously treated eye. An orbitotomy in the first patient disclosed a loculated epithelium-lined inclusion cyst that extended pos...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76169-0
更新日期：1992-04-15 00:00:00
abstract：:Eight aniridic patients with bilateral corneal scarring, vascularization, or edema underwent corneal transplantation in one or both eyes (11 eyes). Follow-up ranged from eight months to 5 1/2 years (average, three years). Six of 11 eyes (55%) had at least a two-line improvement in visual acuity and eight of 11 (73%) h...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73581-0
更新日期：1993-03-15 00:00:00
abstract：:Nerve fiber counts of 16 normal human optic nerves from subjects aged 3.5 to 82 years showed a significant effect of age (P = .0207). The delay between death or enucleation and fixation also significantly affected the result (P = .0078). The mean (+/- S.E.M.) count for the 16 nerves was 1,244,005 +/- 20,033 fibers, gi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90509-9
更新日期：1984-06-01 00:00:00
abstract：PURPOSE:To report a novel mutation of the CYP1B1 gene in a Japanese patient with primary infantile glaucoma. METHODS:DNA was extracted from leukocytes of six unrelated patients with primary infantile glaucoma. The coding regions of the CYP1B1 gene were amplified by polymerase chain reaction, examined by agarose gel se...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00143-9
更新日期：1999-09-01 00:00:00
abstract：PURPOSE:To evaluate the impact of cataract surgery on subfoveal choroidal thickness and central retinal thickness in the elderly. DESIGN:Prospective observational case series. METHODS:This cohort study included 29 eyes of 29 patients with senile cataract, but no previous ocular surgery or other ocular abnormality. Al...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.05.016
更新日期：2014-09-01 00:00:00
